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Abbreviation : PG
Long Form : plakoglobin
No. Year Title Co-occurring Abbreviation
2019 Endocytosis of IgG, Desmoglein 1, and Plakoglobin in Pemphigus Foliaceus Patient Skin. Dsg1, PF
2018 Plakoglobin localization to the cell border restores desmosome function in cells lacking 14-3-3gamma. PG-EGFP-f
2017 Adrenergic Signaling Strengthens Cardiac Myocyte Cohesion. ---
2017 Loss of desmoglein 2 promotes tumorigenic behavior in pancreatic cancer cells. Dsc2, Dsg2
2017 Modification of cysteine 457 in plakoglobin modulates the proliferation and migration of colorectal cancer cells by altering binding to E-cadherin/catenins. CRC, WT
2016 The physical interaction of p53 and plakoglobin is necessary for their synergistic inhibition of migration and invasion. WT
2015 Expression of desmosomal proteins in acantholytic squamous cell carcinoma of the skin. DP 1, DSC1, DSC2, Dsc3, Dsg1, Dsg3, PKP1, SCC
2015 Plakoglobin expression in fibroblasts and its role in idiopathic pulmonary fibrosis. IPF
2014 Plakoglobin but not desmoplakin regulates keratinocyte cohesion via modulation of p38MAPK signaling. DP, p38 MAPK
10  2013 Plakoglobin as a regulator of desmocollin gene expression. Dscs, EDA, EDAR, Lef1
11  2012 Analysis of a Jup hypomorphic allele reveals a critical threshold for postnatal viability. ARVC
12  2012 Loss of cadherin-binding proteins beta-catenin and plakoglobin in the heart leads to gap junction remodeling and arrhythmogenesis. ARVC, Cx43, DKO, ICD, SCD
13  2012 The desmosomal armadillo protein plakoglobin regulates prostate cancer cell adhesion and motility through vitronectin-dependent Src signaling. ECM, VN
14  2011 E-cadherin and plakoglobin recruit plakophilin3 to the cell border to initiate desmosome assembly. PKP3
15  2011 Mechanistic insights into arrhythmogenic right ventricular cardiomyopathy caused by desmocollin-2 mutations. ARVC, ID
16  2011 Molecular genetics and pathogenesis of arrhythmogenic right ventricular cardiomyopathy: a disease of cardiac stem cells. ARVC, DSC2, DSG2
17  2011 Nuclear plakoglobin is essential for differentiation of cardiac progenitor cells to adipocytes in arrhythmogenic right ventricular cardiomyopathy. ARVC, CPCs
18  2010 Homozygous mutations in the 5' region of the JUP gene result in cutaneous disease but normal heart development in children. IF
19  2010 Plakoglobin regulates cell motility through Rho- and fibronectin-dependent Src signaling. ECM, FN
20  2008 P120 catenin is associated with desmogleins when desmosomes are assembled in high-Ca2+ medium but not when disassembled in low-Ca2+ medium in DJM-1 cells. Dsg, E-cad, p120ctn
21  2008 Plakoglobin is required for effective intermediate filament anchorage to desmosomes. ---
22  2008 The most widespread desmosomal cadherin, desmoglein 2, is a novel target of caspase 3-mediated apoptotic machinery. Dsg, STS
23  2007 Keratinocyte transcriptional regulation of the human c-Myc promoter occurs via a novel Lef/Tcf binding element distinct from neoplastic cells. TBE
24  2007 Modulation of the oncogenic potential of beta-catenin by the subcellular distribution of plakoglobin. ---
25  2007 Plakoglobin deficiency protects keratinocytes from apoptosis. ---
26  2007 Plakoglobin-dependent disruption of the desmosomal plaque in pemphigus vulgaris. PV
27  2006 Pemphigus vulgaris identifies plakoglobin as key suppressor of c-Myc in the skin. Dsg, PV
28  2005 Mechanisms of plakoglobin-dependent adhesion: desmosome-specific functions in assembly and regulation by epidermal growth factor receptor. EGF
29  2005 Plakoglobin suppresses keratinocyte motility through both cell-cell adhesion-dependent and -independent mechanisms. ---
30  2004 Coordinated expression of desmoglein 1 and desmocollin 1 regulates intercellular adhesion. DSC1, Dsg1, NHEK
31  2003 De novo formation of desmosomes in cultured cells upon transfection of genes encoding specific desmosomal components. AJ, DP, PP2
32  2001 Molecular cloning of a functional promoter of the human plakoglobin gene. ---
33  2001 Rescuing desmoplakin function in extra-embryonic ectoderm reveals the importance of this protein in embryonic heart, neuroepithelium, skin and vasculature. DP, IF
34  2001 Tyrosine-phosphorylated plakoglobin is associated with desmogleins but not desmoplakin after epidermal growth factor receptor activation. EGF, EGFR
35  2000 Extracellularly truncated desmoglein 1 compromises desmosomes in MDCK cells. DP, Dsc, Dsg, PPs
36  1999 Down-regulation of desmosomal molecules in oral and pharyngeal squamous cell carcinomas as a marker for tumour growth and distant metastasis. DP, SCC
37  1998 Defining the interactions between intermediate filaments and desmosomes. DP, Dsc1a, Dsg1, IFs, PP1
38  1997 Inhibition of junction assembly in cultured epithelial cells by hepatocyte growth factor/scatter factor is concomitant with increased stability and altered phosphorylation of the soluble junctional molecules. CSF-1, HGF/SF, MDCK
39  1996 [Expression of plakoglobin in bronchial carcinomas: incidence and significance for disease outcome]. mAb, NSCLC
40  1995 Plakoglobin: kinetics of synthesis, phosphorylation, stability, and interactions with desmoglein and E-cadherin. MDCK