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[Related PubMed/MEDLINE]
Total Number of Papers: 285
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| Abbreviation |
: PGC1alpha |
| Long Form |
: proliferator-activated receptor gamma coactivator 1-alpha |
|
| No. |
Year |
Title |
Co-occurring Abbreviation |
| 1 |
2021 |
"Cell Membrane Theory of Senescence" and the Role of Bioactive Lipids in Aging, and Aging Associated Diseases and Their Therapeutic Implications. |
AA, ALA, DGLA, GLA, LA, LXA4, PGE2, PLA2, PUFAs |
| 2 |
2021 |
Bariatric surgery can acutely modulate ER-stress and inflammation on subcutaneous adipose tissue in non-diabetic patients with obesity. |
AMPK, BMI, CALR, EIF2AK3, ERS, GCN2, MCP-1, Nrf2, RYGB, TNF-alpha |
| 3 |
2021 |
Effect of the protein hydrolysate of rice syrup meal on the endurance exercise performance of BALB/c mice. |
BCAAs, CON, pAMPK, RL |
| 4 |
2021 |
Inflammation-Induced Protein Unfolding in Airway Smooth Muscle Triggers a Homeostatic Response in Mitochondria. |
ASM, Drp1, ER, Mfn2, mtUPR, PINK1, pIRE1alpha, PTEN, ROS, TNF-alpha |
| 5 |
2021 |
L-Arabinose suppresses gluconeogenesis through modulating AMP-activated protein kinase in metabolic disorder mice. |
ACC, AMPK, FOXO1, G6Pase, HFHSD, HSD, PEPCK |
| 6 |
2021 |
Recovery From Repeat Mild Traumatic Brain Injury in Adolescent Rats Is Dependent on Pre-injury Activity State. |
BDNF, mTBI, rTBI |
| 7 |
2021 |
Sex-based differences after a single bout of exercise on PGC1α isoforms in skeletal muscle: A pilot study. |
EDL, HSP60, IL-6, MHC |
| 8 |
2020 |
A Class I Histone Deacetylase Inhibitor Attenuates Insulin Resistance and Inflammation in Palmitate-Treated C2C12 Myotubes and Muscle of HF/HFr Diet Mice. |
EHHADH, HDAC, HF, HFr, MCAD, PA, PPARalpha, TG |
| 9 |
2020 |
Andrographolide modulates HNF4alpha activity imparting on hepatic metabolism. |
AP, apoB, G6PC, HNF4alpha, MTP, PLA2G12B, VLDL |
| 10 |
2020 |
Antiepileptic Drug-Activated Constitutive Androstane Receptor Inhibits Peroxisome Proliferator-Activated Receptor alpha and Peroxisome Proliferator-Activated Receptor gamma Coactivator 1alpha-Dependent Gene Expression to Increase Blood Triglyceride Levels. |
CAR, PPARalpha |
| 11 |
2020 |
BST204, a Rg3 and Rh2 Enriched Ginseng Extract, Upregulates Myotube Formation and Mitochondrial Function in TNF-alpha-Induced Atrophic Myotubes. |
ROS, TNF-alpha |
| 12 |
2020 |
Cardiopulmonary Bypass Suppresses Forkhead Box O3 and Downstream Autophagy in the Diabetic Human Heart. |
CPB, mTOR, ULK1 |
| 13 |
2020 |
Cerebral Mitochondrial Function and Cognitive Performance during Aging: A Longitudinal Study in NMRI Mice. |
CAT, creb-1, GAP43, NRF-1, SOD2, SYP1 |
| 14 |
2020 |
Cold-Pressed Nigella Sativa Oil Standardized to 3% Thymoquinone Potentiates Omega-3 Protection against Obesity-Induced Oxidative Stress, Inflammation, and Markers of Insulin Resistance Accompanied with Conversion of White to Beige Fat in Mice. |
ACC, AMPK, FGF21, HFD, HO-1, IRbeta, Mfn2, PRDM16, SIRT1, TQ, TWIST2, UCP1, WAT |
| 15 |
2020 |
Complex Mitochondrial Dysfunction Induced by TPP+-Gentisic Acid and Mitochondrial Translation Inhibition by Doxycycline Evokes Synergistic Lethality in Breast Cancer Cells. |
alpha-KGDHC, BC, DMKG, ETC, mAsp |
| 16 |
2020 |
Effect of quercetin on nonshivering thermogenesis of brown adipose tissue in high-fat diet-induced obese mice. |
ADRB3, AMPK, BAT, CIDEA, HFD, MAPK, mtTFA, RWAT, UCP1, WAT |
| 17 |
2020 |
Effects of PGC1α on myocardial ischemia reperfusion injury and the underlying mechanisms. |
ChIP, HIF-1alpha, MitoSOX, TTC |
| 18 |
2020 |
Exercise Training-Induced PPARβ Increases PGC-1α Protein Stability and Improves Insulin-Induced Glucose Uptake in Rodent Muscles. |
CS, Cyto C, Ext, GLUT4, NUO, PPARbeta |
| 19 |
2020 |
Farnesol induces mitochondrial/peroxisomal biogenesis and thermogenesis by enhancing the AMPK signaling pathway in vivo and in vitro. |
AMPKalpha, ATGL, HSL, OCR, OXPHOS, PRDM16, UCP1 |
| 20 |
2020 |
H3K27me3-mediated PGC1alpha gene silencing promotes melanoma invasion through WNT5A and YAP. |
TCF12 |
| 21 |
2020 |
Herbal Combination of Phyllostachys pubescens and Scutellaria baicalensis Inhibits Adipogenesis and Promotes Browning via AMPK Activation in 3T3-L1 Adipocytes. |
AMPK, aP2, FAS, p-ACC, PPARgamma, PRDM16, SREBP-1c, UCP, UPLC |
| 22 |
2020 |
Impact of neural stem cell-derived extracellular vesicles on mitochondrial dysfunction, sirtuin 1 level, and synaptic deficits in Alzheimer's disease. |
AD, EVs, Fis1, GAP43, MAP2, NRF1 and 2, NSC, PSD-95, SIRT1, SYP, Tg |
| 23 |
2020 |
Impairment of mitochondrial dynamics involved in iron oxide nanoparticle-induced dysfunction of dendritic cells was alleviated by autophagy inhibitor 3-methyladenine. |
3-MA, CCR7, DCs, PEG-Fe3 O4 |
| 24 |
2020 |
IRF1-mediated downregulation of PGC1alpha contributes to cardiorenal syndrome type 4. |
CKD, CRS4, HP, IRF-1 |
| 25 |
2020 |
Klotho ameliorates diabetic nephropathy via LKB1-AMPK-PGC1α-mediated renal mitochondrial protection. |
AMPK, DN, HG, rKL, ROS |
| 26 |
2020 |
Macrophage MSR1 promotes BMSC osteogenic differentiation and M2-like polarization by activating PI3K/AKT/GSK3beta/beta-catenin pathway. |
BMDMs, BMSC, IO, KO, MSR1, WT |
| 27 |
2020 |
Mangiferin induces the expression of a thermogenic signature via AMPK signaling during brown-adipocyte differentiation. |
CIDEA, COX-2, cox7A, Dio2, MF, NRF-1, PPARalpha and gamma, PRDM16, SIRT1 |
| 28 |
2020 |
Melatonin improves mitochondrial biogenesis through the AMPK/PGC1α pathway to attenuate ischemia/reperfusion-induced myocardial damage. |
AMPK |
| 29 |
2020 |
Meta-analyses of the association between the PPARGC1A Gly482Ser polymorphism and athletic performance. |
--- |
| 30 |
2020 |
Methylglyoxal-Dependent Glycative Stress and Deregulation of SIRT1 Functional Network in the Ovary of PCOS Mice. |
AGEs, AMPK, DHEA, MG, mtTFA, PCOS, RAGEs, SIRT1, SOD2, TOMM20 |
| 31 |
2020 |
PGC1alpha suppresses kidney cancer progression by inhibiting collagen-induced SNAIL expression. |
DDR1, RCC |
| 32 |
2020 |
PGC1α protects against hepatic steatosis and insulin resistance via enhancing IL10-mediated anti-inflammatory response. |
HFD |
| 33 |
2020 |
Phosphodiesterase Inhibitors for Alzheimer's Disease: A Systematic Review of Clinical Trials and Epidemiology with a Mechanistic Rationale. |
AD, cAMP, cGMP, CREB, PKA, PKG |
| 34 |
2020 |
Possible role of garlic oil in ameliorating renal injury after liver ischemia/reperfusion in rats. |
ATG7, HO1, I/R, TAC |
| 35 |
2020 |
PPARγ/PGC1α signaling as a potential therapeutic target for mitochondrial biogenesis in neurodegenerative disorders. |
AD, HD, PD, PON2, PPARgamma, UCP2 |
| 36 |
2020 |
Proteomic analysis of mitochondrial biogenesis in cardiomyocytes differentiated from human induced pluripotent stem cells. |
BCAA, CMs, FAO, hiPSC-CMs, IPA, IR, NRVMs, OXPHOS, TCA |
| 37 |
2020 |
Pyruvate dehydrogenase kinase 1 interferes with glucose metabolism reprogramming and mitochondrial quality control to aggravate stress damage in cancer. |
DCA, PDK1 |
| 38 |
2020 |
Sildenafil for the Treatment of Alzheimer's Disease: A Systematic Review. |
AD, cAMP, cGMP, PDE2, PDE5 |
| 39 |
2020 |
Silencing of peroxisome proliferator-activated receptor-alpha alleviates myocardial injury in diabetic cardiomyopathy by downregulating 3-hydroxy-3-methylglutaryl-coenzyme A synthase 2 expression. |
ANP, BNP, DCM, HMGCS2, MMP, NRF, PPARalpha, ROS, TGF-beta1 |
| 40 |
2020 |
Sirt1-PPARS Cross-Talk in Complex Metabolic Diseases and Inherited Disorders of the One Carbon Metabolism. |
DT2, PI3K, Sirt1 |
| 41 |
2020 |
Soy isoflavones improve the oxidative stress induced hypothalamic inflammation and apoptosis in high fat diet-induced obese male mice through PGC1-alpha pathway. |
--- |
| 42 |
2020 |
Stimulation of brown adipose tissue by polyphenols in extra virgin olive oil. |
AMPK, EVOO, SIRT1 |
| 43 |
2020 |
Targeting Energy Pathways in Kidney Disease: The Roles of Sirtuins, AMPK, and PGC1α. |
AMPK |
| 44 |
2020 |
The effect of 12-week resistance exercise training on serum levels of cellular aging process parameters in elderly men. |
RT, SIRT1, SIRT3, SIRT6 |
| 45 |
2020 |
The effect of alpha-lipoic acid supplementation and electrical isotonic contraction on anthropometric parameters, body composition and angiogenesis factor, sirtunin-1 and peroxisome proliferator-activated receptor-gamma coactivator-1alpha in obese people under a weight loss regime: A study protocol for a randomized controlled clinical trial. |
--- |
| 46 |
2020 |
The effects of curcumin supplementation on oxidative stress, Sirtuin-1 and peroxisome proliferator activated receptor γ coactivator 1α gene expression in polycystic ovarian syndrome (PCOS) patients: A randomized placebo-controlled clinical trial. |
GPx, PCOS, SIRT1, SOD |
| 47 |
2020 |
The inhibition of eIF5A hypusination by GC7, a preconditioning protocol to prevent brain death-induced renal injuries in a preclinical porcine kidney transplantation model. |
BD |
| 48 |
2020 |
The PGC1α/NRF1-MPC1 axis suppresses tumor progression and enhances the sensitivity to sorafenib/doxorubicin treatment in hepatocellular carcinoma. |
HCC, MPC1, NRF-1, ROS |
| 49 |
2020 |
Time-Restricted Feeding Improves Body Weight Gain, Lipid Profiles, and Atherogenic Indices in Cafeteria-Diet-Fed Rats: Role of Browning of Inguinal White Adipose Tissue. |
AC, AIP, CAF, CRI, iWAT, NC, TC, TG, TRF, UCP1 |
| 50 |
2020 |
Transcription factor EB and TFE3: new metabolic coordinators mediating adaptive responses to exercise in skeletal muscle? |
TFEB |
| 51 |
2020 |
Unripe Rubus coreanus Miquel Extract Containing Ellagic Acid Promotes Lipolysis and Thermogenesis In Vitro and In Vivo. |
ATGL, CPT1, eWAT, HFD, ingWAT, p-HSL, PLIN1, PPARalpha, UCP1 |
| 52 |
2019 |
Alpha lipoic acid protects against dexamethasone-induced metabolic abnormalities via APPL1 and PGC-1 alpha up regulation. |
ALA, GCs, IRS-1, PI3K |
| 53 |
2019 |
Black Raspberry (Rubus coreanus Miquel) Promotes Browning of Preadipocytes and Inguinal White Adipose Tissue in Cold-Induced Mice. |
BRWE, DM, EA, hMSCs, iWAT, PRDM16, TBX1, UCP1, WAT |
| 54 |
2019 |
Bronchial thermoplasty decreases airway remodelling by blocking epithelium-derived heat shock protein-60 secretion and protein arginine methyltransferase-1 in fibroblasts. |
BALF, BT, Epi.S, HSP60, PRMT1 |
| 55 |
2019 |
Cardioprotective Heme Oxygenase-1-PGC1alpha Signaling in Epicardial Fat Attenuates Cardiovascular Risk in Humans as in Obese Mice. |
HO-1, LV |
| 56 |
2019 |
Dual peroxisome-proliferator-activated-receptor-alpha/gamma activation inhibits SIRT1-PGC1alpha axis and causes cardiac dysfunction. |
PPAR, SIRT1 |
| 57 |
2019 |
Effect of PGC1-beta ablation on myonuclear organisation. |
EDL, MND, PGC-1beta, WT |
| 58 |
2019 |
Eicosapentaenoic Acid Reduces Adiposity, Glucose Intolerance and Increases Oxygen Consumption Independently of Uncoupling Protein 1. |
BAT, EPA, HF, KO, mtDNA, nucDNA, UCP1, WT |
| 59 |
2019 |
ETHE1 overexpression promotes SIRT1 and PGC1alpha mediated aerobic glycolysis, oxidative phosphorylation, mitochondrial biogenesis and colorectal cancer. |
AMP, AMPKp, CRC, ETHE1, FAP, PDE, SIRT1 |
| 60 |
2019 |
First High-Resolution Crystal Structures of the Glucocorticoid Receptor Ligand-Binding Domain-Peroxisome Proliferator-Activated gamma Coactivator 1-alpha Complex with Endogenous and Synthetic Glucocorticoids. |
DEX, GR, HCY, LBD, NR |
| 61 |
2019 |
FXR activation alleviates tacrolimus-induced post-transplant diabetes mellitus by regulating renal gluconeogenesis and glucose uptake. |
FOXO1, FXR, GLUT2, PEPCK, PTDM |
| 62 |
2019 |
Ginsenoside Rg3 upregulates myotube formation and mitochondrial function, thereby protecting myotube atrophy induced by tumor necrosis factor-alpha. |
MHC, MMP, NRF-1, TNF-alpha |
| 63 |
2019 |
GLP‑1 improves palmitate‑induced insulin resistance in human skeletal muscle via SIRT1 activity. |
cAMP, GLUT4, HSMMs, PKA, siRNA, SIRT1 |
| 64 |
2019 |
High released lactate by epicardial fat from coronary artery disease patients is reduced by dapagliflozin treatment. |
CAD, EAT, SAT |
| 65 |
2019 |
Human Ovarian Cancer Tissue Exhibits Increase of Mitochondrial Biogenesis and Cristae Remodeling. |
mtDNA, OC, OPA1, PCA, PHB2, SIRT3 |
| 66 |
2019 |
IgE Downregulates PTEN through MicroRNA-21-5p and Stimulates Airway Smooth Muscle Cell Remodeling. |
ASMC, IgE, PI3K, PPAR-gamma, PTEN, STAT3 |
| 67 |
2019 |
Influence of pre-pregnancy body mass index (p-BMI) and gestational weight gain (GWG) on DNA methylation and protein expression of obesogenic genes in umbilical vein. |
GNPDA2, GWG, LEPR, MS-HRM, pBMI |
| 68 |
2019 |
Investigation of mitochondrial DNA copy number in patients with major depressive disorder. |
D-loop, MDD, mtDNA |
| 69 |
2019 |
Jiang Gui Fang activated interscapular brown adipose tissue and induced epididymal white adipose tissue browning through the PPARgamma/SIRT1-PGC1alpha pathway. |
eWAT, HSL, IBAT, JG, KM, PPARgamma, SIRT1, UCP1 |
| 70 |
2019 |
Metabolic regulation of exercise-induced angiogenesis. |
ECs, ERRgamma, SIRT1, VEGF |
| 71 |
2019 |
MicroRNA-10a Impairs Liver Metabolism in Hepatitis C Virus-Related Cirrhosis Through Deregulation of the Circadian Clock Gene Brain and Muscle Aryl Hydrocarbon Receptor Nuclear Translocator-Like 1. |
Bmal1, CHC, FASN, LRH1, miRNAs, mTOR, RORA, S6K, SREBP |
| 72 |
2019 |
miR-23b-3p suppressing PGC1α promotes proliferation through reprogramming metabolism in osteosarcoma. |
OS, OXPHOS |
| 73 |
2019 |
Molecular Characterization of Peroxisome Proliferator-Activated Receptor-Gamma Coactivator-1alpha (PGC1alpha) and Its Role in Mitochondrial Biogenesis in Blunt Snout Bream (Megalobrama amblycephala). |
siRNA |
| 74 |
2019 |
Musclin, A Myokine Induced by Aerobic Exercise, Retards Muscle Atrophy During Cancer Cachexia in Mice. |
AREG, caFoxO3, FGF18, KO, NPPB, Npr3, TA |
| 75 |
2019 |
Noggin depletion in adipocytes promotes obesity in mice. |
BMPs, UCP1 |
| 76 |
2019 |
Perivascular adipose tissue-derived stromal cells contribute to vascular remodeling during aging. |
hPVASCs, PVAT |
| 77 |
2019 |
PGC1alpha downregulation and glycolytic phenotype in thyroid cancer. |
--- |
| 78 |
2019 |
PGC1alpha Inhibits Polyamine Synthesis to Suppress Prostate Cancer Aggressiveness. |
ODC1 |
| 79 |
2019 |
Protection against HEMA-Induced Mitochondrial Injury In Vitro by Nrf2 Activation. |
hDPCs, HEMA, HO-1, NRF-1, Nrf2, tBHQ |
| 80 |
2019 |
Pterostilbene reverses palmitic acid mediated insulin resistance in HepG2 cells by reducing oxidative stress and triglyceride accumulation. |
CREB, G6Pase, IR, JNK, NOX3, PA, PC, PEPCK, PTS, ROS |
| 81 |
2019 |
Renoprotective effects of brown adipose tissue activation in diabetic mice. |
AMPK, BAT, DKD, FGF, miRNA, SIRT1, STZ |
| 82 |
2019 |
SIRT3-Dependent Mitochondrial Dynamics Remodeling Contributes to Oxidative Stress-Induced Melanocyte Degeneration in Vitiligo. |
ChIP, Co-IP, OPA1, SIRT3 |
| 83 |
2019 |
Sparc, an EPS-induced gene, modulates the extracellular matrix and mitochondrial function via ILK/AMPK pathways in C2C12 cells. |
AMPK, ECM, EPS, GSK-3ss, ILK, p-AMPK, p-GSK-3ss, SPARC |
| 84 |
2019 |
Taking KLF9 to "Cort" for crimes against metabolism. |
GCs, KLF9 |
| 85 |
2019 |
Testosterone Deficiency Caused by Castration Modulates Mitochondrial Biogenesis Through the AR/PGC1alpha/TFAM Pathway. |
AR, mtDNA |
| 86 |
2019 |
TFEB-driven lysosomal biogenesis is pivotal for PGC1α-dependent renal stress resistance. |
TFEB |
| 87 |
2019 |
The effect of apelin-13 on pancreatic islet beta cell mass and myocardial fatty acid and glucose metabolism of experimental type 2 diabetic rats. |
PPAR |
| 88 |
2019 |
The osteogenic effect of liraglutide involves enhanced mitochondrial biogenesis in osteoblasts. |
AdipoR1, AMPK, GLP1R, LIRA, P1NP |
| 89 |
2019 |
TIGAR regulates mitochondrial functions through SIRT1-PGC1alpha pathway and translocation of TIGAR into mitochondria in skeletal muscle. |
KO, SIRT1, TIGAR, WT |
| 90 |
2019 |
TLR4 signaling modulation of PGC1-alpha mediated mitochondrial biogenesis in the LPS-Chronic mild stress model: Effect of fluoxetine and pentoxiyfylline. |
AD, FLX, LPS, PTX, TLR4 |
| 91 |
2019 |
[FGF21 inhibits lipid accumulation and inflammation induced by palmitate in human hepatocytes via SIRT1 pathway]. |
CAT, FGF21, IL-6, MDA, OCR, ROS, SOD2, TNF-alpha |
| 92 |
2018 |
A Novel Tetramethylpyrazine Derivative Protects Against Glutamate-Induced Cytotoxicity Through PGC1alpha/Nrf2 and PI3K/Akt Signaling Pathways. |
CGNs, HO-1, Nrf2, p-Akt, p-PI3K |
| 93 |
2018 |
A Screen Using iPSC-Derived Hepatocytes Reveals NAD+ as a Potential Treatment for mtDNA Depletion Syndrome. |
iPSCs, MTDPS3, NAD, RRM2B |
| 94 |
2018 |
Acetylation of PGC1alpha by Histone Deacetylase 1 Downregulation Is Implicated in Radiation-Induced Senescence of Brain Endothelial Cells. |
HDAC1 |
| 95 |
2018 |
Bovine lactoferrin promotes energy expenditure via the cAMP-PKA signaling pathway in human reprogrammed brown adipocytes. |
bLF, cAMP, CREB, LF, LRP1, RAP, UCP1 |
| 96 |
2018 |
Chronic Exercise Improves Mitochondrial Function and Insulin Sensitivity in Brown Adipose Tissue. |
BAT, CPT II, Drp1, ET, IGF-1R, IR, L-OPA1, Mfn1, NRF-1, p-IRS-1, S-OPA1, SIRT1, UCP |
| 97 |
2018 |
Cycling CD4+ T cells in HIV-infected immune nonresponders have mitochondrial dysfunction. |
INR, TFAM |
| 98 |
2018 |
delta-Tocopherol promotes thermogenic gene expression via PGC-1alpha upregulation in 3T3-L1 cells. |
MAPK, UCP1 |
| 99 |
2018 |
Dietary ursolic acid improves health span and life span in male Drosophila melanogaster. |
srl, UA |
| 100 |
2018 |
Dihydromyricetin Ameliorates Nonalcoholic Fatty Liver Disease by Improving Mitochondrial Respiratory Capacity and Redox Homeostasis Through Modulation of SIRT3 Signaling. |
AMPK, DHM, ERRalpha, HFD, NAFLD, SIRT3KO |
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