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Abbreviation : PHB1
Long Form : prohibitin 1
No. Year Title Co-occurring Abbreviation
2020 HDAC6 promotes sepsis development by impairing PHB1-mediated mitochondrial respiratory chain function. CLP, HDAC6
2020 Involvement of prohibitin 1 and prohibitin 2 upregulation in cBSA-induced podocyte cytotoxicity. cBSA, IHC, MN, PHB2
2020 Mitochondrial dysfunction during loss of prohibitin 1 triggers Paneth cell defects and ileitis. IBD
2020 Molecular characterization of prohibitins and their differential responses to WSSV infection in hemocyte subpopulations of Fenneropenaeus chinensis. IFA, pAbs
2020 Prohibitin 1 (PHB1) controls growth and development and regulates proliferation and apoptosis in Schistosoma japonicum. ---
2020 Prohibitin 1 interacts with signal transducer and activator of transcription 3 in T-helper 17 cells. IL, STAT3, Th17
2020 Regulatory effects of Prohibitin 1 on proliferation and apoptosis of pulmonary arterial smooth muscle cells in monocrotaline-induced PAH rats. HE, PAH, PASMCs, PCNA, RV, RVSP
2020 The Synthetic Small Molecule FL3 Combats Intestinal Tumorigenesis via Axin1-Mediated Inhibition of Wnt/beta-Catenin Signaling. ---
2019 FoxM1 Induced Paclitaxel Resistance via Activation of the FoxM1/PHB1/RAF-MEK-ERK Pathway and Enhancement of the ABCA2 Transporter. ---
10  2019 Glucose starvation-induced oxidative stress causes mitochondrial dysfunction and apoptosis via Prohibitin 1 upregulation in human breast cancer cells. Drp1, GS, MMP, NAC, OCR, TNBCs
11  2019 Long-Term Feeding of Soy Protein Attenuates Choline Deficient-Induced Adverse Effects in Wild Type Mice and Prohibitin 1 Deficient Mice Response More Sensitively. CDD, NAFLD, SPD
12  2019 LPLUNC1 stabilises PHB1 by counteracting TRIM21-mediated ubiquitination to inhibit NF-kappaB activity in nasopharyngeal carcinoma. LPLUNC1, NPC
13  2019 Prohibitin (PHB) expression is associated with aggressiveness in DLBCL and flavagline-mediated inhibition of cytoplasmic PHB functions induces anti-tumor effects. ABC, DLBCLs, EFS, GCB, IHC, PHB, PHB2
14  2019 Prohibitins: A Critical Role in Mitochondrial Functions and Implication in Diseases. PHB2
15  2019 The mitochondrial chaperone Prohibitin 1 negatively regulates interleukin-8 in human liver cancers. HCC, IL-8, JNK
16  2018 Prohibitin 1 Acts As a Negative Regulator of Wingless/Integrated-Beta-Catenin Signaling in Murine Liver and Human Liver Cancer Cells. GSK-3, HCC, IGF2, KO, mRNA, Wnt
17  2017 MicroRNA-195 acts as an anti-proliferative miRNA in human melanoma cells by targeting Prohibitin 1. ---
18  2017 Multifunctional Envelope-Type siRNA Delivery Nanoparticle Platform for Prostate Cancer Therapy. NP, PCa, PSMA, RNAi, siRNA
19  2017 Prohibitin 1 suppresses liver cancer tumorigenesis in mice and human hepatocellular and cholangiocarcinoma cells. CCA, HCC, MATalpha1
20  2017 Targeting prohibitins with chemical ligands inhibits KRAS-mediated lung tumours. EGF, NSCLCs
21  2017 [Effects of exhaustive exercise on the expression of PHB1 and the function of mitochondria in rats]. RCR, ROS, ST3, ST4
22  2016 Prohibitin 1 Regulates the H19-Igf2 Axis and Proliferation in Hepatocytes. CTCF, HCC, ICR, IGF2
23  2016 The protective role of protein L-isoaspartyl (D-aspartate) O-methyltransferase for maintenance of mitochondrial morphology in A549 cell. COPD, D-Asp, D-aspartate, IPF
24  2015 A Novel Class of Small Molecule Compounds that Inhibit Hepatitis C Virus Infection by Targeting the Prohibitin-CRaf Pathway. HCV, Roc-A
25  2015 Activation of a novel c-Myc-miR27-prohibitin 1 circuitry in cholestatic liver injury inhibits glutathione synthesis in mice. ARE, BDL, LCA, Nrf2
26  2015 F-box protein 7 mutations promote protein aggregation in mitochondria and inhibit mitophagy. FBXO7, PD, WT
27  2015 Histone deacetylase 4 promotes cholestatic liver injury in the absence of prohibitin-1. HDAC4
28  2015 Identification of prohibitin 1 as a potential prognostic biomarker in human pancreatic carcinoma using modified aqueous two-phase partition system combined with 2D-MALDI-TOF-TOF-MS/MS. MALDI, TOF
29  2015 Long-circulating siRNA nanoparticles for validating Prohibitin1-targeted non-small cell lung cancer treatment. lipid-PEG, NP, NSCLC, RNAi, siRNA
30  2015 miR-361-regulated prohibitin inhibits mitochondrial fission and apoptosis and protects heart from ischemia injury. MI
31  2015 Prohibitin 1 gene delivery promotes functional recovery in rats with spinal cord injury. PI3K, SCI
32  2014 Characterization of PHB1 and its role in mitochondrial maturation and yolk platelet degradation during development of Artemia embryos. ---
33  2014 Effect of all-trans retinoic acid treatment on prohibitin and renin-angiotensin-aldosterone system expression in hypoxia-induced renal tubular epithelial cell injury. ATRA, PHB, PHB2, RTEC
34  2014 Hybrid lipid-polymer nanoparticles for sustained siRNA delivery and gene silencing. NP, RNAi, siRNA
35  2014 Interaction of delta-like 1 homolog (Drosophila) with prohibitins and its impact on tumor cell clonogenicity. ---
36  2013 A role for prohibitin in mast cell activation: location matters. IgE
37  2013 Differential expression and subcellular localization of Prohibitin 1 are related to tumorigenesis and progression of non-small cell lung cancer. NSCLC
38  2013 Nuclear accumulation of prohibitin 1 in osteoarthritic chondrocytes down-regulates PITX1 expression. OA, RT-PCR
39  2012 Mitochondrial dysfunction and adipogenic reduction by prohibitin silencing in 3T3-L1 cells. PHB2, PHBs
40  2011 Marine natural product aurilide activates the OPA1-mediated apoptosis by binding to prohibitin. OPA1
41  2011 The role and therapeutic potential of prohibitin in disease. ---
42  2010 Liver-specific deletion of prohibitin 1 results in spontaneous liver injury, fibrosis, and hepatocellular carcinoma in mice. HCC, KO, MAT1A
43  2010 Prohibitins are required for cancer cell proliferation and adhesion. PHB2
44  2010 Rescue of paclitaxel sensitivity by repression of Prohibitin1 in drug-resistant cancer cells. ---
45  2009 Prohibitins and the functional compartmentalization of mitochondrial membranes. PHB2
46  2009 Severe acute respiratory syndrome coronavirus nonstructural protein 2 interacts with a host protein complex involved in mitochondrial biogenesis and intracellular signaling. nsp's, SARS-CoV
47  2008 Prohibitin-1 maintains the angiogenic capacity of endothelial cells by regulating mitochondrial function and senescence. ---
48  2003 Functional proteomics of nonalcoholic steatohepatitis: mitochondrial proteins as targets of S-adenosylmethionine. AdoMet