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Abbreviation : PHB2
Long Form : prohibitin 2
No. Year Title Co-occurring Abbreviation
2020 Bax inhibitor 1 preserves mitochondrial homeostasis in acute kidney injury through promoting mitochondrial retention of PHB2. AKI, BI1, IRI
2020 Interaction between PHB2 and Enterovirus A71 VP1 Induces Autophagy and Affects EV-A71 Infection. EV-A71, HFMD
2020 Involvement of prohibitin 1 and prohibitin 2 upregulation in cBSA-induced podocyte cytotoxicity. cBSA, IHC, MN, PHB1
2020 Prohibitin 2 deficiency impairs cardiac fatty acid oxidation and causes heart failure. CPT1b, FAO
2020 Prohibitin 2/PHB2 in Parkin-Mediated Mitophagy: A Potential Therapeutic Target for Non-Small Cell Lung Carcinoma. MMP, NSCLC, TEM
2019 Biophysical characterization of the breast cancer-related BIG3-PHB2 interaction: Effect of non-conserved loop region of BIG3 on the structure and the interaction. BIG3
2019 Human Ovarian Cancer Tissue Exhibits Increase of Mitochondrial Biogenesis and Cristae Remodeling. mtDNA, OC, OPA1, PCA, PGC1alpha, SIRT3
2019 Mitoquinone attenuates blood-brain barrier disruption through Nrf2/PHB2/OPA1 pathway after subarachnoid hemorrhage in rats. EBI, MitoQ, Nrf2, OPA1, SAH, siRNA
2019 Prohibitin (PHB) expression is associated with aggressiveness in DLBCL and flavagline-mediated inhibition of cytoplasmic PHB functions induces anti-tumor effects. ABC, DLBCLs, EFS, GCB, IHC, PHB, PHB1
10  2019 Prohibitin 2-mediated mitophagy attenuates renal tubular epithelial cells injury by regulating mitochondrial dysfunction and NLRP3 inflammasome activation. ---
11  2019 Prohibitins: A Critical Role in Mitochondrial Functions and Implication in Diseases. PHB1
12  2018 Lamprey Prohibitin2 Arrest G2/M Phase Transition of HeLa Cells through Down-regulating Expression and Phosphorylation Level of Cell Cycle Proteins. qRT-PCR
13  2018 LncRNA-CARl in a rat model of myocardial infarction. Bax, Bcl-2, CCK-8, HE, lncRNA-CARL, MI
14  2018 PHB2 interacts with LC3 and SQSTM1 is required for bile acids-induced mitophagy in cholestatic liver. BA, SQSTM1
15  2018 Prohibitin 2 localizes in nucleolus to regulate ribosomal RNA transcription and facilitate cell proliferation in RD cells. rDNA, RMS
16  2018 Prohibitin-2 is a novel regulator of p21WAF1/CIP1 induced by depletion of gamma-glutamylcyclotransferase. GGCT
17  2018 Prohibitin-2 negatively regulates AKT2 expression to promote prostate cancer cell migration. AKT2, PCa
18  2018 Small-molecule screening yields a compound that inhibits the cancer-associated transcription factor Hes1 via the PHB2 chaperone. Hes1, TLE1
19  2018 TDP-43 interacts with mitochondrial proteins critical for mitophagy and mitochondrial dynamics. ALS/MND, CCCP, FTLD, Mfn2, TDP-43, TEM, VDAC1
20  2018 The novel long noncoding RNA LOC283070 is involved in the transition of LNCaP cells into androgen-independent cells via its interaction with PHB2. AR, lncRNA, MTT, qRT-PCR, RIP
21  2017 Molecular characterization and function of the Prohibitin2 gene inLitopenaeus vannamei responses to Vibrio alginolyticus. ---
22  2017 Olfactory bulb neuroproteomics reveals a chronological perturbation of survival routes and a disruption of prohibitin complex during Alzheimer's disease progression. AD, APP, FTLD, OB, PKC, PSP
23  2017 Overexpression of sphingosine-1-phosphate lyase protects insulin-secreting cells against cytokine toxicity. Bad, BiP, CHOP, ER, S1P
24  2017 Prohibitin 2 Is an Inner Mitochondrial Membrane Mitophagy Receptor. LIR
25  2016 Abundance of specific mRNA transcripts impacts hatching success in European eel, Anguilla anguilla L. cpt1, IGF2, pigf5
26  2016 Prohibitin-2 Depletion Unravels Extra-Mitochondrial Functions at the Kidney Filtration Barrier. SPFH
27  2015 BIG3 Inhibits the Estrogen-Dependent Nuclear Translocation of PHB2 via Multiple Karyopherin-Alpha Proteins in Breast Cancer Cells. BIG3, ERalpha, KPNA
28  2015 Differential binding of prohibitin-2 to estrogen receptor alpha and to drug-resistant ERalpha mutants. ERalpha, WT
29  2015 Identification and characterisation of the anti-oxidative stress properties of the lamprey prohibitin 2 gene. ADR, CHL, rLm-PHB2
30  2015 Inhibition of insulin/IGF-1 receptor signaling protects from mitochondria-mediated kidney failure. S6RP
31  2015 Prohibitin 2: At a communications crossroads. PHB1, PHBs
32  2015 Prohibitin-2 gene reveals sex-related differences in the salmon louse Caligus rogercresseyi. bp, ORF, SNPs
33  2015 The Interferon-Inducible Mouse Apolipoprotein L9 and Prohibitins Cooperate to Restrict Theiler's Virus Replication. Apol9b, ISG, MuHV-4, phb1, TMEV, VSV
34  2014 Effect of all-trans retinoic acid treatment on prohibitin and renin-angiotensin-aldosterone system expression in hypoxia-induced renal tubular epithelial cell injury. ATRA, PHB, PHB1, RTEC
35  2014 Expression of PHB2 in rat brain cortex following traumatic brain injury. CNS, TBI
36  2014 Prohibitin 2 regulates the proliferation and lineage-specific differentiation of mouse embryonic stem cells in mitochondria. ES
37  2014 Prohibitin-2 promotes hepatocellular carcinoma malignancy progression in hypoxia based on a label-free quantitative proteomics strategy. HCC
38  2014 Xanthohumol suppresses oestrogen-signalling in breast cancer through the inhibition of BIG3-PHB2 interactions. ERalpha, XN
39  2013 Co-immunoprecipitation-based identification of putative BAX INHIBITOR-1-interacting proteins involved in cell death regulation and plant-powdery mildew interactions. AAL, AHA1, BI-1, Co-IP, CYP83A1, ER, FRET, GFP, VHA-A
40  2013 Prohibitin-2 binding modulates insulin-like growth factor-binding protein-6 (IGFBP-6)-induced rhabdomyosarcoma cell migration. IGF, IGFBP-6, RMS
41  2012 Casein kinase 1 proteomics reveal prohibitin 2 function in molecular clock. ---
42  2012 Mitochondrial dysfunction and adipogenic reduction by prohibitin silencing in 3T3-L1 cells. PHB1, PHBs
43  2011 CaMK IV phosphorylates prohibitin 2 and regulates prohibitin 2-mediated repression of MEF2 transcription. CaMK IV
44  2011 Mitochondrial prohibitins and septin 9 are implicated in the onset of rat hepatocarcinogenesis. PHB, SEPT9
45  2011 Sphingosine-1-phosphate produced by sphingosine kinase 2 in mitochondria interacts with prohibitin 2 to regulate complex IV assembly and respiration. S1P, SphK2
46  2010 Prohibitins are required for cancer cell proliferation and adhesion. PHB1
47  2009 Prohibitins and the functional compartmentalization of mitochondrial membranes. PHB1
48  2007 Microarray-based analysis of fish egg quality after natural or controlled ovulation. APOC1
49  2007 PHB2 protects sister-chromatid cohesion in mitosis. RNAi
50  2006 Mitochondrial functions and estrogen receptor-dependent nuclear translocation of pleiotropic human prohibitin 2. ---
51  2004 Akt binds prohibitin 2 and relieves its repression of MyoD and muscle differentiation. ---