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Abbreviation : PI4,5P2
Long Form : phosphatidylinositol 4,5-bisphosphate
No. Year Title Co-occurring Abbreviation
2022 Crucial Players for Inter-Organelle Communication: PI5P4Ks and Their Lipid Product PI-4,5-P2 Come to the Surface. PI5P4Ks
2021 Discovery and Characterization of the Potent and Highly Selective 1,7-Naphthyridine-Based Inhibitors BAY-091 and BAY-297 of the Kinase PIP4K2A. PI5P
2021 PIP5KIγ90-generated phosphatidylinositol-4,5-bisphosphate promotes the uptake of Staphylococcus aureus by host cells. PIP5KIgamma
2021 Properties of FDA-approved small molecule phosphatidylinositol 3-kinase inhibitors prescribed for the treatment of malignancies. Ala-Pro-Glu, GPCRs, PI 3-kinase, PIP3
2020 A role for alpha-Synuclein in axon growth and its implications in corticostriatal glutamatergic plasticity in Parkinson's disease. PD, WMTs
2020 Distribution and localization of phosphatidylinositol 5-phosphate, 4-kinase alpha and beta in the brain. ---
2020 Phosphatidylinositol 4,5-bisphosphate in the Control of Membrane Trafficking. ---
2019 OSBP-related protein 2 (ORP2): Unraveling its functions in cellular lipid/carbohydrate metabolism, signaling and F-actin regulation. LDs, LTPs, ORP2, OSBP, PM, TG
2019 Transient Gene Expression as a Tool to Monitor and Manipulate the Levels of Acidic Phospholipids in Plant Cells. PA, PI4P, PS
10  2018 Phosphatidylinositol 4-phosphate is a major source of GPCR-stimulated phosphoinositide production. DAG, GPCRs, IP, PI4P, PKD, PLC, PM
11  2018 Phosphoinositide 3-kinase pathways and autophagy require phosphatidylinositol phosphate kinases. PIPKs
12  2018 The phosphorylation status of PIP5K1C at serine 448 can be predictive for invasive ductal carcinoma of the breast. PIP5K1C
13  2017 Exocyst subunit SEC3A marks the germination site and is essential for pollen germination in Arabidopsis thaliana. ---
14  2015 IQGAP1 is a phosphoinositide effector and kinase scaffold. PIPKI
15  2015 Phosphorylation regulates the Star-PAP-PIPKIalpha interaction and directs specificity toward mRNA targets. PAP
16  2013 Plant phosphoinositide-dependent phospholipases C: variations around a canonical theme. DAG, PA, PI-PLC
17  2012 Divalent cation-induced cluster formation by polyphosphoinositides in model membranes. FCS, PPIs, SP-FRET
18  2012 Plasma membrane proteins Slm1 and Slm2 mediate activation of the AGC kinase Ypk1 by TORC2 and sphingolipids in S. cerevisiae. PM, TORC2
19  2010 Type I gamma phosphatidylinositol phosphate kinase modulates invasion and proliferation and its expression correlates with poor prognosis in breast cancer. EGFR
20  2007 A conspicuous connection: structure defines function for the phosphatidylinositol-phosphate kinase family. PIP
21  2007 Phosphorothiolate analogues of phosphatidylinositols as assay substrates for phospholipase C. PI-PLC
22  2003 Essential Ca(2+)-independent role of the group IVA cytosolic phospholipase A(2) C2 domain for interfacial activity. GIVAPLA2, PIPns
23  2000 Characterization of phosphatidylinositol, phosphatidylinositol-4-phosphate, and phosphatidylinositol-4,5-bisphosphate by electrospray ionization tandem mass spectrometry: a mechanistic study. CAD, PI, PI4P, PIP
24  1999 Polyphosphoinositides inhibit the interaction of vinculin with actin filaments. ---
25  1999 Wortmannin, an inhibitor of phosphatidylinositol kinases, blocks the MgATP-dependent recovery of Kir6.2/SUR2A channels. ---
26  1998 A phosphatidylinositol 4-kinase pleckstrin homology domain that binds phosphatidylinositol 4-monophosphate. PH, PI, PI-4-P
27  1997 SHIP, a new player in cytokine-induced signalling. 5PTase, I-1,3,4,5-P4, I-1,4,5-P3, PI-3,4,5-P3
28  1994 Phosphatidylinositol 3-kinase binds to alpha-actinin through the p85 subunit. PI 3-kinase
29  1991 The effect of ischaemia and reperfusion on sarcolemmal inositol phospholipid and cytosolic inositol phosphate metabolism in the isolated perfused rat heart. PI, PI4P
30  1989 PDGF-dependent tyrosine phosphorylation stimulates production of novel polyphosphoinositides in intact cells. PDGF, PI, PI-3,4-P2, PI-3-P, PI4P, SMC
31  1988 Alpha 1-adrenoceptor-mediated phosphoinositide breakdown and inotropic response in rat left ventricular papillary muscles. ---
32  1985 Evidence for a Ca2+-independent hydrolysis of phosphatidylinositol 4,5-bisphosphate in neuron-like cell line NG108-15 cells. ---
33  1985 Phosphoinositide interconversion in thrombin-stimulated human platelets. PI, PI4P
34  1984 Bradykinin-induced rapid breakdown of phosphatidylinositol 4,5-bisphosphate in neuroblastoma X glioma hybrid NG108-15 cells. ---
35  1984 Hydrolysis of polyphosphoinositides by purified sheep seminal vesicle phospholipase C enzymes. PI, PI4P, PLC