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Abbreviation : PLB
Long Form : Plumbagin
No. Year Title Co-occurring Abbreviation
2020 NADPH: Quinone oxidoreductase 1 (NQO1) mediated anti-cancer effects of plumbagin in endocrine resistant MCF7 breast cancer cells. NQO1
2020 Plumbagin attenuated oxygen-glucose deprivation/reoxygenation-induced injury in human SH-SY5Y cells by inhibiting NOX4-derived ROS-activated NLRP3 inflammasome. 4-HNE, MDA, NOX4, OGDR, ROS
2020 Plumbagin Enhances the Anticancer Efficacy of Cisplatin by Increasing Intracellular ROS in Human Tongue Squamous Cell Carcinoma. ROS, TSCC
2020 Plumbagin inhibited AKT signaling pathway in HER-2 overexpressed-endocrine resistant breast cancer cells. ER, NCOA3, p-AKT
2020 Up and down-regulation of mRNA in the cytotoxicity and genotoxicity of Plumbagin in HepG2/C3A. ---
2019 Molecular pathways related to the control of proliferation and cell death in 786-O cells treated with plumbagin. ---
2019 Plumbagin induces paraptosis in cancer cells by disrupting the sulfhydryl homeostasis and proteasomal function. ER
2019 Plumbagin inhibits cancer stem-like cells, angiogenesis and suppresses cell proliferation and invasion by targeting Wnt/beta-catenin pathway in endocrine resistant breast cancer. CSLCs, EMT, FGF-2
2018 Current development in novel drug delivery systems of bioactive molecule plumbagin. ---
10  2018 Inhibitory Effects of Plumbagin on Retinal Pigment Epithelial Cell Epithelial-Mesenchymal Transition In Vitro and In Vivo. EMT, ERG, MMPs, OCT, PVR, RPE
11  2018 Plumbagin induces RPE cell cycle arrest and apoptosis via p38 MARK and PI3K/AKT/mTOR signaling pathways in PVR. p38 MAPK, PI3K
12  2018 Plumbagin inhibits the proliferation of nasopharyngeal carcinoma 6-10B cells by upregulation of reactive oxygen species. ---
13  2018 Plumbagin Triggers ER Stress-Mediated Apoptosis in Prostate Cancer Cells via Induction of ROS. PCa, ROS
14  2018 Plumbagin-mediating GLUT1 suppresses the growth of human tongue squamous cell carcinoma. TSCC
15  2017 Targeting thioredoxin reductase by plumbagin contributes to inducing apoptosis of HL-60cells. ---
16  2017 The naphthoquinone plumbagin suppresses ADP-induced rat platelet aggregation through P2Y1-PLC signaling pathway. ---
17  2016 Plumbagin Enhances Tamoxifen Sensitivity and Inhibits Tumor Invasion in Endocrine Resistant Breast Cancer through EMT Regulation. EMT
18  2015 Induction of apoptosis and autophagy via sirtuin1- and PI3K/Akt/mTOR-mediated pathways by plumbagin in human prostate cancer cells. AMPK, MAPK, mTOR, PI3K, ROS, SIRT1
19  2015 Plumbagin elicits differential proteomic responses mainly involving cell cycle, apoptosis, autophagy, and epithelial-to-mesenchymal transition pathways in human prostate cancer PC-3 and DU145 cells. EMT, SILAC
20  2015 Plumbagin induces cell cycle arrest and autophagy and suppresses epithelial to mesenchymal transition involving PI3K/Akt/mTOR-mediated pathway in human pancreatic cancer cells. p38 MAPK, PI3K
21  2015 Plumbagin-silver nanoparticle formulations enhance the cellular uptake of plumbagin and its antiproliferative activities. ---
22  2014 Plumbagin induces apoptotic and autophagic cell death through inhibition of the PI3K/Akt/mTOR pathway in human non-small cell lung cancer cells. ---
23  2012 Plumbagin reverses proliferation and resistance to apoptosis in experimental PAH. IL, NFAT, PAH, PASMC, PCNA, ROCK, STAT
24  2010 Plumbagin-induced apoptosis in lymphocytes is mediated through increased reactive oxygen species production, upregulation of Fas, and activation of the caspase cascade. Con A, DNFB, LPS, NAC, ROS, SEB
25  2001 Mutagenicity of nitric oxide-releasing compounds in Escherichia coli: effect of superoxide generation and evidence for two mutagenic mechanisms. DEA/NO, NO, SPER/NO