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Abbreviation : PP
Long Form : protein phosphatase
No. Year Title Co-occurring Abbreviation
2019 Age-Dependent Protein Expression of Serine/Threonine Phosphatases and Their Inhibitors in the Human Cardiac Atrium. ACE, AT1, NYHA
2019 Blockade of AMPA Receptor Regulates Mitochondrial Dynamics by Modulating ERK1/2 and PP1/PP2A-Mediated DRP1-S616 Phosphorylations in the Normal Rat Hippocampus. AMPAR, Drp1, JNK, NMDAR, p38 MAPK
2019 Blocking Tyr265 nitration of protein phosphatase 2A attenuates nitrosative stress-induced endothelial dysfunction in renal microvessels. EndMT, TAT, Tyr
2019 Perampanel Affects Up-Stream Regulatory Signaling Pathways of GluA1 Phosphorylation in Normal and Epileptic Rats. JNK, PKA, PKC
2019 Protein Phosphatase 2A Regulates Cardiac Na+ Channels. ---
2019 Proteomic analysis of the hepatotoxicity of Microcystis aeruginosa in adult zebrafish (Danio rerio) and its potential mechanisms. MCs
2018 Caffeic acid phenethyl ester down-regulates claudin-2 expression at the transcriptional and post-translational levels and enhances chemosensitivity to doxorubicin in lung adenocarcinoma A549 cells. CAPE
2018 Changes in potassium channel modulation may underlie afterhyperpolarization plasticity in oxytocin neurons during late pregnancy. AHPs, CK2, ImAHP, OA, OT, TBB
2018 ERalpha36 gene silencing promotes tau protein phosphorylation, inhibits cell proliferation, and induces apoptosis in human neuroblastoma SH-SY5Y cells. Bax, Bcl, CCK, ER, GSK, MEK, mTOR, p-tau, PCNA
10  2018 Invivo assessment of the hepatotoxicity of a new Nostoc isolate from the Nile River: Nostoc sp. strain NRI. MCs, WHO
11  2018 Membrane-Initiated Estrogen Receptor Signaling Mediates Metabolic Homeostasis via Central Activation of Protein Phosphatase 2A. ER
12  2018 Neuroprotective Effect of Protein Phosphatase 2A/Tristetraprolin Following Subarachnoid Hemorrhage in Rats. EBI, IL, SAH, si, TNF, TTP
13  2018 PINK1 suppresses alpha-synuclein-induced neuronal injury: a novel mechanism in protein phosphatase 2A activation. alpha-Syn, PD, PINK, PTEN
14  2018 PP2A negatively regulates the hypertrophic response by dephosphorylating HDAC2 S394 in the heart. HDAC
15  2018 Protein Phosphatase 1 dephosphorylates TDP-43 and suppresses its function in tau exon 10 inclusion. TDP-43
16  2018 Spinal protein phosphatase 1 constrains respiratory plasticity after sustained hypoxia. pLTF, PPs
17  2018 Subthalamic nucleus deep brain stimulation protects neurons by activating autophagy via PP2A inactivation in a rat model of Parkinson's disease. Bcl, DBS, PD, STN
18  2018 The role of dual‑specificity phosphatase 1 and protein phosphatase1 in beta2‑adrenergic receptor‑mediated inhibition of extracellular signal regulated kinase 1/2 in triple negative breast cancer cell lines. DUSP, ERK, si
19  2017 How Protein Kinase A Activates Canonical Tyrosine Kinase Signaling Pathways To Promote Granulosa Cell Differentiation. DUSP, FSH, GC, IGF-1R, IRS-1, MAPK/ERK, MKP, PI3K, PKA, RTKs
20  2017 Overexpression of betaCaMKII impairs behavioral flexibility and NMDAR-dependent long-term depression in the dentate gyrus. AMPAR, CaMKII, DG, GSK3beta, LTD, MPP, NM, NMDAR, Tg
21  2017 Protein phosphatase 2A regulation of markers of extracellular matrix remodelling in hepatocellular carcinoma cells: functional consequences for tumour invasion. MMP, OA
22  2017 Protein phosphatase 2C is responsible for VP-induced dephosphorylation of AQP2 serine 261. AQP2, VP
23  2017 Toward Neuroproteomics in Biological Psychiatry: A Systems Approach Unravels Okadaic Acid-Induced Alterations in the Neuronal Phosphoproteome. OA
24  2016 A proteomic study on liver impairment in rat pups induced by maternal microcystin-LR exposure. GD8, MCs, PD15, ROS
25  2016 Endotoxin Tolerance Inhibits Lyn and c-Src Phosphorylation and Association with Toll-Like Receptor 4 but Increases Expression and Activity of Protein Phosphatases. LPS, MKP, NF, PTP, PTPN, TLR
26  2016 Mechanism of Oxidative Stress and Synapse Dysfunction in the Pathogenesis of Alzheimer's Disease: Understanding the Therapeutics Strategies. AD, CaMKII, CREB, ERK, MAPK, NMDA
27  2016 Synthesis of Highly Selective Submicromolar Microcystin-Based Inhibitors of Protein Phosphatase (PP)2A over PP1. MC
28  2016 Theophylline Represses IL-8 Secretion from Airway Smooth Muscle Cells Independently of Phosphodiesterase Inhibition. Novel Role as a Protein Phosphatase 2A Activator. ASM, MAPK, PDE
29  2015 Alpha-synuclein overexpression negatively regulates insulin receptor substrate 1 by activating mTORC1/S6K1 signaling. alpha-Syn, IRS, mTOR, S6K
30  2015 Black Soybean Seed Coat Extract Prevents Hydrogen Peroxide-Mediated Cell Death via Extracellular Signal-Related Kinase Signalling in HepG2 Cells. BE, HPO
31  2015 Counteracting Protein Kinase Activity in the Heart: The Multiple Roles of Protein Phosphatases. PKs
32  2015 eIF2alpha-Independent Inhibition of TNF-alpha-Triggered NF-kappaB Activation by Salubrinal. eIF2alpha, IL, NF-kappaB, siRNA, TGF, TNF
33  2015 Histone Deacetylase 3 and 4 Complex Stimulates the Transcriptional Activity of the Mineralocorticoid Receptor. HDACs, MR, PKA
34  2015 Identification of kinases, phosphatases, and phosphorylation sites in human and porcine spermatozoa. CaMK, CK, CREB, MAPK, PKA, PKB, PKC
35  2015 Inhibition of protein kinase (PK) Cdelta attenuates methamphetamine-induced dopaminergic toxicity via upregulation of phosphorylation of tyrosine hydroxylase at Ser40 by modulation of protein phosphatase 2A and PKA. ASO, MA, PK, TH
36  2015 Micro(mi) RNA-34a targets protein phosphatase (PP)1gamma to regulate DNA damage tolerance. ATM, DDR, IR, mi, PP1gamma, UTR
37  2015 Naringin attenuates the cytotoxicity of hepatotoxin microcystin-LR by the curious mechanisms to OATP1B1- and OATP1B3-expressing cells. ROS
38  2015 Nodularin-triggered apoptosis and hyperphosphorylation of signaling proteins in cultured rat hepatocytes. NOD
39  2015 Overexpression of protein phosphatase 2A in a murine model of chronic myocardial infarction leads to increased adverse remodeling but restores the regulation of beta-catenin by glycogen synthase kinase 3beta. PP2A, WT
40  2015 Pathologic Regulation of Collagen I by an Aberrant Protein Phosphatase 2A/Histone Deacetylase C4/MicroRNA-29 Signal Axis in Idiopathic Pulmonary Fibrosis Fibroblasts. HDA, IPF, miR
41  2015 Phosphatase PP4 Negatively Regulates Type I IFN Production and Antiviral Innate Immunity by Dephosphorylating and Deactivating TBK1. TBK1
42  2015 PP6 controls T cell development and homeostasis by negatively regulating distal TCR signaling. ---
43  2015 Rapid detection of protein phosphatase activity using Zn(II)-coordinated gold nanosensors based on His-tagged phosphopeptides. NTA, PP1, PP2A
44  2015 Restricted protein phosphatase 2A targeting by Merkel cell polyomavirus small T antigen. LSD, MCV, MS, PP2A, ST, SV40
45  2015 Stimulation of the cardiac myocyte Na+-K+ pump due to reversal of its constitutive oxidative inhibition. Ip, sGC
46  2015 Suggested Involvement of PP1/PP2A Activity and De Novo Gene Expression in Anhydrobiotic Survival in a Tardigrade, Hypsibius dujardini, by Chemical Genetic Approach. ---
47  2014 A STRESS-RESPONSIVE NAC1-regulated protein phosphatase gene rice protein phosphatase18 modulates drought and oxidative stress tolerance through abscisic acid-independent reactive oxygen species scavenging in rice. ABA, ROS, SNAC1
48  2014 beta(2)-Adrenergic and M(2)-muscarinic receptors decrease basal t-tubular L-type Ca2+ channel activity and suppress ventricular contractility in heart failure. DPCPX, SS, TT
49  2014 Effects of light and the regulatory B-subunit composition of protein phosphatase 2A on the susceptibility of Arabidopsis thaliana to aphid (Myzus persicae) infestation. ---
50  2014 Okadaic acid blocks the effects of 5-aza-2-deoxycytidine on consolidation, acquisition and retrieval of morphine-induced place preference in rats. 5-Aza, mCPP, OA, PL
51  2014 Protein phosphatase complex PP5/PPP2R3C dephosphorylates P-glycoprotein/ABCB1 and down-regulates the expression and function. P-gp
52  2014 Sarcoplasmic reticulum Ca2+ cycling protein phosphorylation in a physiologic Ca2+ milieu unleashes a high-power, rhythmic Ca2+ clock in ventricular myocytes: relevance to arrhythmias and bio-pacemaker design. PDE, PLB, RyR, SANC, SR, VM
53  2014 Termination mechanism of CREB-dependent activation of COX-2 expression in early phase of adipogenesis. CRE, PG, PKA
54  2014 TGF-beta1 protection against Abeta1-42-induced neuroinflammation and neurodegeneration in rats. AD, APP, i.c.v, TGF, Th
55  2014 Threonine-290 regulates nuclear translocation of the human pregnane X receptor through its phosphorylation/dephosphorylation by Ca2+/calmodulin-dependent protein kinase II and protein phosphatase 1. CaMKII, hPXR, siRNA
56  2014 Tributyltin induces a G2/M cell cycle arrest in human amniotic cells via PP2A inhibition-mediated inactivation of the ERK1/2 cascades. TBT
57  2013 Comparative toxicological study of the novel protein phosphatase inhibitor 19-Epi-okadaic acid in primary cultures of rat cerebellar cells. OKA
58  2013 Development of a colorimetric and a fluorescence phosphatase-inhibitor assay suitable for drug discovery approaches. HTS
59  2013 Inhibition of PP2A and the consequent activation of JNK/c-Jun are involved in tributyltin-induced apoptosis in human amnionic cells. MAPKs, TBT
60  2013 Role of serine-threonine phosphoprotein phosphatases in smooth muscle contractility. MLC20, MPs, MYPT1
61  2013 Zinc induces protein phosphatase 2A inactivation and tau hyperphosphorylation through Src dependent PP2A (tyrosine 307) phosphorylation. AD
62  2012 Activation of AMP-activated protein kinase stimulates Na+,K+-ATPase activity in skeletal muscle cells. AICAR, AMPK, PME-1
63  2012 Adenosine-mediated inhibition of 5'-AMP-activated protein kinase and p38 mitogen-activated protein kinase during reperfusion enhances recovery of left ventricular mechanical function. ADO, AMPK, GI, LV, PFK-2
64  2012 Bi-directional regulation of CaMKIIalpha phosphorylation at Thr286 by NMDA receptors in cultured cortical neurons. NMDA, NR2A, NR2B
65  2012 Bioaccumulation, oxidative stress and HSP70 expression in Cyprinus carpio L. exposed to microcystin-LR under laboratory conditions. GST, MC-LR, MDA
66  2012 Caveolae compartmentalise beta2-adrenoceptor signals by curtailing cAMP production and maintaining phosphatase activity in the sarcoplasmic reticulum of the adult ventricular myocyte. ARs, MBCD, p-PLB, PDE, PI3K
67  2012 Chronic receptor-mediated activation of Gi/o proteins alters basal t-tubular and sarcolemmal L-type Ca⁺ channel activity through phosphatases in heart failure. PTX, SS, TT
68  2012 Cytokines alter glucocorticoid receptor phosphorylation in airway cells: role of phosphatases. ASMCs, CSI, GCs, GR, Ser211
69  2012 Different signaling mechanisms are involved in the norepinephrine-stimulated TORC1 and TORC2 nuclear translocation in rat pinealocytes. NE, TORC
70  2012 Direct interactions of ABA-insensitive(ABI)-clade protein phosphatase(PP)2Cs with calcium-dependent protein kinases and ABA response element-binding bZIPs may contribute to turning off ABA response. ABA, ABI, bZIP
71  2012 Enriched environment prevents cognitive impairment and tau hyperphosphorylation after chronic cerebral hypoperfusion. AD, CaMKII, CCH, EE, GSK-3beta, VaD
72  2012 Human and rat hepatocyte toxicity and protein phosphatase 1 and 2A inhibitory activity of naturally occurring desmethyl-microcystins and nodularins. MCs, NOD
73  2012 Identification and characterization of protein phosphatase 2C activation by ceramide. ---
74  2012 Increased phosphorylation of tau and synaptic protein loss in the aged transgenic mice expressing familiar Alzheimer's disease-linked presenilin 1 mutation. AD, CDK, GSK, PS1, PSD, WTs
75  2012 Interaction of protein phosphatase 1delta with nucleophosmin in human osteoblastic cells. ---
76  2012 Involvement of CaM kinase II in the impairment of endothelial function and eNOS activity in aortas of Type 2 diabetic rats. CA, GK, PPI2
77  2012 Lentivirus-mediated silencing of I2PP2A through RNA interference attenuates trichloroethylene-induced cytotoxicity in human hepatic L-02 cells. I2PP2A, RNAi, TCE
78  2012 MARCKS dephosphorylation is involved in bradykinin-induced neurite outgrowth in neuroblastoma SH-SY5Y cells. BK, CNS, GST, MARCKS, PDBu, PKC, PLC, ROCK
79  2012 Oxidative stress response in zebrafish (Danio rerio) gill experimentally exposed to subchronic microcystin-LR. LPO, MC-LR
80  2012 PICOT increases cardiac contractility by inhibiting PKCzeta activity. AAV, PKC, PLB, Tn
81  2012 Pravastatin normalizes ET-1-induced contraction in the aorta of type 2 diabetic OLETF rats by suppressing the KSR1/ERK complex. ET, KSR, LETO, OLETF
82  2012 Protein phosphatase 1 is involved in IL-2-induced IL-5 and IL-13 expression in human T cells. IL-2R
83  2011 Antifungal activity of tautomycin and related compounds against Sclerotinia sclerotiorum. PDA
84  2011 Development of a colorimetric inhibition assay for microcystin-LR detection: comparison of the sensitivity of different protein phosphatases. MC-LR, WHO
85  2011 Interaction of Mrp2 with radixin causes reversible canalicular Mrp2 localization induced by intracellular redox status. GSH-EE, MRP2, nPKC, p-radixin, PKA, t-BHP
86  2011 Melatonin ameliorates Alzheimer-like pathological changes and spatial memory retention impairment induced by calyculin A. ---
87  2011 Melatonin reduces the impairment of axonal transport and axonopathy induced by calyculin A. CA
88  2011 Modulation of calcium-dependent inactivation of L-type Ca2+ channels via beta-adrenergic signaling in thalamocortical relay neurons. AKAP, beta-AR, HVA, PKA, TC
89  2011 Protein phosphatase 2A affects myofilament contractility in non-failing but not in failing human myocardium. NF
90  2011 Protein phosphatases: possible bisphosphonate binding sites mediating stimulation of osteoblast proliferation. BP, NaF, PTP
91  2011 Synthesis and characterization of pseudocantharidins, novel phosphatase modulators that promote the inclusion of exon 7 into the SMN (survival of motoneuron) pre-mRNA. ---
92  2010 Acetyl-L-carnitine attenuates okadaic acid induced tau hyperphosphorylation and spatial memory impairment in rats. AD, ALCAR, OA
93  2010 Alterations in GluR2 AMPA receptor phosphorylation at serine 880 following group I metabotropic glutamate receptor stimulation in the rat dorsal striatum. AMPA, CaMK, JNK, mGluRs, NMDA, PKC, PLC
94  2010 CaMKII phosphorylates serine 10 of p27 and confers apoptosis resistance to HeLa cells. DN-PP6
95  2010 Functional characterization of TtnD and TtnF, unveiling new insights into tautomycetin biosynthesis. TTN
96  2010 Gossypol exerts its cytotoxic effect on HL-60 leukemic cell line via decreasing activity of protein phosphatase 2A and interacting with human telomerase reverse transcriptase activity. hTERT
97  2010 Increment of activated serine/threonine protein phosphatase in brain membrane fraction synchronized with antinociceptive effect of morphine in mice. OA
98  2010 Investigation of microcystin congener-dependent uptake into primary murine neurons. MCs, mOatp1b2
99  2010 Nuclear export and centrosome targeting of the protein phosphatase 2A subunit B56alpha: role of B56alpha in nuclear export of the catalytic subunit. FRAP, NES
100  2010 Phenylbutyric acid prevents rats from electroconvulsion-induced memory deficit with alterations of memory-related proteins and tau hyperphosphorylation. CREB, ECS, GSK-3beta, PBA, PERK, PSD95