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Abbreviation : PPARalpha
Long Form : proliferator-activated receptor alpha
No. Year Title Co-occurring Abbreviation
2022 2,4-dichlorophenol exposure induces lipid accumulation and reactive oxygen species formation in zebrafish embryos. 2,4-DCP, ACC, GPx, ROS
2021 Echinacoside improves diabetic liver injury by regulating the AMPK/SIRT1 signaling pathway in db/db mice. CPT1A, ECH, FBG, PGC-1alpha
2021 FXR, a Key Regulator of Lipid Metabolism, Is Inhibited by ER Stress-Mediated Activation of JNK and p38 MAPK in Large Yellow Croakers (Larimichthys crocea) Fed High Fat Diets. ER, FXR, HNF-1alpha, SREBP1
2020 Keratocytes promote corneal neovascularization through VEGFr3 induced by PPARalpha-inhibition. CNV, qRT-PCR, WB
2020 MiR-9-5p protects from kidney fibrosis by metabolic reprogramming. BPs, FAO, miRNAs, OXPHOS, PGC-1alpha, RNA-Seq, TGF-beta1, UUO
2020 Perfluorooctanoic acid (PFOA), perfluorooctane sulfonic acid (PFOS), and perfluorononanoic acid (PFNA) increase triglyceride levels and decrease cholesterogenic gene expression in human HepaRG liver cells. GSEA, PFASs, PFNA, PFOA, PFOS
2020 PPARalpha-Dependent Modulation by Metformin of the Expression of OCT-2 and MATE-1 in the Kidney of Mice. ---
2020 Radix Polygoni Multiflori and Its Main Component Emodin Attenuate Non-Alcoholic Fatty Liver Disease in Zebrafish by Regulation of AMPK Signaling Pathway. ACOX1, AMPKalpha, CPT-1a, IR, NAFLD, NEFA, PI3K, RPMP, TC, TG
2019 Astragaloside IV Alleviates the Myocardial Damage Induced by Lipopolysaccharide via the Toll-Like Receptor 4 (TLR4)/Nuclear Factor kappa B (NF-kappaB)/Proliferator-Activated Receptor alpha (PPARalpha) Signaling Pathway. AMP, AS-IV, ATP, FFA, IL-1ss, IL-6, LPS, NF-kappaB, TLR4, TNF-alpha
10  2018 Coordination Among Lipid Droplets, Peroxisomes, and Mitochondria Regulates Energy Expenditure Through the CIDE-ATGL-PPARalpha Pathway in Adipocytes. ATGL, BAT, LD, WAT
11  2018 Delphinidin Ameliorates Hepatic Triglyceride Accumulation in Human HepG2 Cells, but Not in Diet-Induced Obese Mice. AMPK, Dp, HFHC, LKB1, mRNA, NAFLD, SIRT1
12  2018 Methyl dehydroabietate counters high fat diet-induced insulin resistance and hepatic steatosis by modulating peroxisome proliferator-activated receptor signaling in mice. HFD, mDA
13  2017 Acetaminophen-Induced Liver Injury Alters the Acyl Ethanolamine-Based Anti-Inflammatory Signaling System in Liver. NAE, OEA
14  2016 Free Fatty Acids Increase Intracellular Lipid Accumulation and Oxidative Stress by Modulating PPARalpha and SREBP-1c in L-02 Cells. FFA, NAFLD, SREBP-1c
15  2016 Increased fatty acid beta-oxidation as a possible mechanism for fat-reducing effect of betaine in broilers. CPT I, FAS, HADH, HMGR, LDL-C, mRNA, NEFA, TC, TG
16  2016 Rice Koji Extract Enhances Lipid Metabolism through Proliferator-Activated Receptor Alpha (PPARalpha) Activation in Mouse Liver. HODEs, LIA, OA, RKE
17  2015 Evaluation of PPARalpha activation by known blueberry constituents. BBX
18  2015 Role of peroxisome proliferator-activated receptor alpha in the expression of hepatic fatty acid oxidation-related genes in chickens. ACO, CPT1a, HAD, mRNA
19  2014 PPARalpha gene polymorphisms modulate the association between physical activity and cardiometabolic risk. CMR
20  2012 Ulcerative colitis impairs the acylethanolamide-based anti-inflammatory system reversal by 5-aminosalicylic acid and glucocorticoids. 5-ASA, NAE, UC
21  2007 Expression of hepatic UDP-glucuronosyltransferase 1A1 and 1A6 correlated with increased expression of the nuclear constitutive androstane receptor and peroxisome proliferator-activated receptor alpha in male rats fed a high-fat and high-sucrose diet. CAR, MRP, OATP, UGT
22  2001 Replication of the wild type and a natural hepatitis B virus nucleocapsid promoter variant is differentially regulated by nuclear hormone receptors in cell culture. HBV, HNF-4, RXRalpha
23  1994 Structure of the mouse peroxisome proliferator activated receptor alpha gene. ---