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Abbreviation : PS
Long Form : pantothenate synthetase
No. Year Title Co-occurring Abbreviation
2018 A highly active pantothenate synthetase from Corynebacterium glutamicum enables the production of D-pantothenic acid with high productivity. ---
2018 Alanine mutation of the catalytic sites of Pantothenate Synthetase causes distinct conformational changes in the ATP binding region. FEL, MD, PCA
2018 Modular Enzymatic Cascade Synthesis of Vitamin B5 and Its Derivatives. ADC, GAD, MAL
2017 Design, synthesis, molecular-docking and antimycobacterial evaluation of some novel 1,2,3-triazolyl xanthenones. 4a-h
2016 Confirmation of a Protein-Protein Interaction in the Pantothenate Biosynthetic Pathway by Using Sortase-Mediated Labelling. ---
2016 Design, synthesis and biological evaluation of imidazo[2,1-b]thiazole and benzo[d]imidazo[2,1-b]thiazole derivatives as Mycobacterium tuberculosis pantothenate synthetase inhibitors. Mtb
2016 Synthesis, in vitro antimycobacterial evaluation and docking studies of some new 5,6,7,8-tetrahydropyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4(3H)-one schiff bases. MDR, Mtb, TB, XDR
2015 Design of Novel Mycobacterium tuberculosis Pantothenate Synthetase Inhibitors: Virtual Screening, Synthesis and In Vitro Biological Activities. Mtb
2014 Development of novel tetrahydrothieno[2,3-c]pyridine-3-carboxamide based Mycobacterium tuberculosis pantothenate synthetase inhibitors: molecular hybridization from known antimycobacterial leads. Mtb
10  2014 Identification and development of 2-methylimidazo[1,2-a]pyridine-3-carboxamides as Mycobacterium tuberculosis pantothenate synthetase inhibitors. Mtb
11  2013 Development of 3-phenyl-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine derivatives as novel Mycobacterium tuberculosis pantothenate synthetase inhibitors. 6ac, Mtb
12  2013 The crystal structure of a novel phosphopantothenate synthetase from the hyperthermophilic archaea, Thermococcus onnurineus NA1. CoA, PanK, PoK, PPS
13  2011 A comparison of the dynamics of pantothenate synthetase from M. tuberculosis and E. coli: computational studies. MTB PS
14  2009 Pantoate kinase and phosphopantothenate synthetase, two novel enzymes necessary for CoA biosynthesis in the Archaea. CoA, PanK, PoK, PPS
15  2008 5-tert-butyl-N-pyrazol-4-yl-4,5,6,7-tetrahydrobenzo[d]isoxazole-3-carboxamide derivatives as novel potent inhibitors of Mycobacterium tuberculosis pantothenate synthetase: initiating a quest for new antitubercular drugs. ---
16  2008 A novel isoform of pantothenate synthetase in the Archaea. ---
17  2008 Towards engineering increased pantothenate (vitamin B(5)) levels in plants. ADC, KPHMT, KPR
18  2007 A novel inhibitor of Mycobacterium tuberculosis pantothenate synthetase. ACP, ATP, CoA
19  2006 Crystal structure of the pantothenate synthetase from Mycobacterium tuberculosis, snapshots of the enzyme in action. ---
20  2003 Crystal structures of a pantothenate synthetase from M. tuberculosis and its complexes with substrates and a reaction intermediate. ---