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Abbreviation : PS
Long Form : peak shortening
No. Year Title Co-occurring Abbreviation
2015 17-beta estradiol attenuates ovariectomy-induced changes in cardiomyocyte contractile function via activation of AMP-activated protein kinase. AMPK, KD, TPS, TR90
2015 alpha,beta-Unsaturated aldehyde pollutant acrolein suppresses cardiomyocyte contractile function: Role of TRPV1 and oxidative stress. FFI, ROS, TPS, TR90
2015 The Modulation of Cardiac Contractile Function by the Pharmacological and Toxicological Effects of Urocortin2. aSvg-30, PKA, PLN, Ucn2
2014 Ablation of Akt2 protects against lipopolysaccharide-induced cardiac dysfunction: role of Akt ubiquitination E3 ligase TRAF6. LPS, TRAF6
2014 alpha,beta-Unsaturated aldehyde crotonaldehyde triggers cardiomyocyte contractile dysfunction: role of TRPV1 and mitochondrial function. FFI, ROS, TPS, TR90
2014 Alpha1 catalytic subunit of AMPK modulates contractile function of cardiomyocytes through phosphorylation of troponin I. ACC, TR90
2014 Inhibition of protein kinase C betaII isoform ameliorates methylglyoxal advanced glycation endproduct-induced cardiomyocyte contractile dysfunction. AGE, MG-AGE, PKC, TPS, TR90
2013 Inhibition of DNA methylation attenuates low-dose cadmium-induced cardiac contractile and intracellular Ca(2+) anomalies. 5-Aza, FS, TR90
2013 Inhibition of protein kinase C betaII isoform rescues glucose toxicity-induced cardiomyocyte contractile dysfunction: role of mitochondria. PKC, TPS, TR90
10  2013 Tauroursodeoxycholic acid mitigates high fat diet-induced cardiomyocyte contractile and intracellular Ca2+ anomalies. ER, IPGTT, JNK, TEM, TUDCA
11  2012 Ca+2/calmodulin-dependent protein kinase mediates glucose toxicity-induced cardiomyocyte contractile dysfunction. CaM, TPS
12  2012 Chronic social stress induces cardiomyocyte contractile dysfunction and intracellular Ca2+ derangement in rats. SD, SERCA2a, SOD1, TPS, VBS
13  2012 Short-term lenalidomide (Revlimid) administration ameliorates cardiomyocyte contractile dysfunction in ob/ob obese mice. ER, ERK, FasL, IL-6, TNF-alpha
14  2012 The effect of ligustrazine on L-type calcium current, calcium transient and contractility in rabbit ventricular myocytes. ISO
15  2011 Azelnidipine prevents cardiac dysfunction in streptozotocin-diabetic rats by reducing intracellular calcium accumulation, oxidative stress and apoptosis. AZL, CCB, i.p, MnSOD, STZ, TPS
16  2011 Deficiency of insulin-like growth factor 1 reduces vulnerability to chronic alcohol intake-induced cardiomyocyte mechanical dysfunction: role of AMPK. AMPK, JNK, LID
17  2011 [Cardiac metallothionein overexpression improves cardiac contractile function and attenuates oxidative stress in lipopolysaccharide-treated mice]. FFI, LPS, MT, TPS
18  2010 Anthrax lethal toxin suppresses murine cardiomyocyte contractile function and intracellular Ca2+ handling via a NADPH oxidase-dependent mechanism. TPS
19  2010 Caspase-3 knock-down reverses contractile dysfunction induced by sepsis in adult rat ventricular myocytes. ARVMs, C-3 siRNA, NA
20  2010 Interaction between age and obesity on cardiomyocyte contractile function: role of leptin and stress signaling. TPS
21  2010 Macrophage migration inhibitory factor deficiency augments cardiac dysfunction in Type 1 diabetic murine cardiomyocytes. ACC, AMPK, MIF, MIF-KO, WT
22  2009 Adiponectin improves cardiomyocyte contractile function in db/db diabetic obese mice. ER, JNK
23  2009 Advanced glycation endproduct (AGE) accumulation and AGE receptor (RAGE) up-regulation contribute to the onset of diabetic cardiomyopathy. AGE, LVDP, MG-AGE, MMP, RAGE, TPS
24  2009 Cardiomyocyte contractile dysfunction in the APPswe/PS1dE9 mouse model of Alzheimer's disease. ER, TPS, TR, WT
25  2009 Contractile response of norepinephrine is modulated by caspase-3 in adult rat ventricular myocytes isolated from septic rat heart. ARVM, NE
26  2009 Creatine kinase inhibitor iodoacetamide antagonizes calcium-stimulated inotropy in cardiomyocytes. ---
27  2009 Neuronostatin inhibits cardiac contractile function via a protein kinase A- and JNK-dependent mechanism in murine hearts. JNK, LVDP, TPS
28  2009 The protease inhibitor UCF-101 ameliorates streptozotocin-induced mouse cardiomyocyte contractile dysfunction in vitro: role of AMP-activated protein kinase. AMPK, ERK, GSK-3beta, JNK, SERCA2a, STZ, XIAP
29  2008 Amidization of doxorubicin alleviates doxorubicin-induced contractile dysfunction and reduced survival in murine cardiomyocytes. THPA, TMSA, TPS
30  2008 Deficiency of insulin-like growth factor 1 reduces sensitivity to aging-associated cardiomyocyte dysfunction. AMPK, IGF-1, LID, mTOR, TPS
31  2008 IGF-I alleviates diabetes-induced RhoA activation, eNOS uncoupling, and myocardial dysfunction. DHFR, eNOS, FVB, L-NAME, NO, TR90
32  2007 Cardiac overexpression of antioxidant catalase attenuates aging-induced cardiomyocyte relaxation dysfunction. AGE, HWD, MHC, PLB, SERCA2a, TPS90, TR90
33  2007 Cardiac-specific overexpression of catalase prolongs lifespan and attenuates ageing-induced cardiomyocyte contractile dysfunction and protein damage. ---
34  2007 Cardiac-specific overexpression of insulin-like growth factor 1 attenuates aging-associated cardiac diastolic contractile dysfunction and protein damage. endo, IGF-1, SERCA2a
35  2007 Catalase alleviates cardiomyocyte dysfunction in diabetes: role of Akt, Forkhead transcriptional factor and silent information regulator 2. GSK-3beta, SIRT2, TPS
36  2007 Chromium (D-phenylalanine)3 improves obesity-induced cardiac contractile defect in ob/ob mice. d-phe, TR90
37  2007 Dietary interaction of high fat and marginal copper deficiency on cardiac contractile function. PLB
38  2007 Influence of gender on oxidative stress, lipid peroxidation, protein damage and apoptosis in hearts and brains from spontaneously hypertensive rats. MDA, SHR, TPS, TR90, WKY
39  2007 Insulin-like growth factor I deficiency prolongs survival and antagonizes paraquat-induced cardiomyocyte dysfunction: role of oxidative stress. LID
40  2007 Interaction between high-fat diet and alcohol dehydrogenase on ethanol-elicited cardiac depression in murine myocytes. ADH, FVB, TR90
41  2006 Cardiac contractile dysfunction in Lep/Lep obesity is accompanied by NADPH oxidase activation, oxidative modification of sarco(endo)plasmic reticulum Ca2+-ATPase and myosin heavy chain isozyme switch. endo, MHC
42  2006 Cardiac overexpression of catalase rescues cardiac contractile dysfunction induced by insulin resistance: Role of oxidative stress, protein carbonyl formation and insulin sensitivity. endo, eNOS, HWD, PPARgamma, PTP1B, ROS, TPS, TR90
43  2006 Cardiac overexpression of metallothionein attenuates chronic alcohol intake-induced cardiomyocyte contractile dysfunction. FFI, SERCA2a, TR90
44  2006 Cardiac overexpression of metallothionein rescues chronic alcohol intake-induced cardiomyocyte dysfunction: role of Akt, mammalian target of rapamycin and ribosomal p70s6 kinase. mTOR, p70S6K, TPS
45  2006 Characterization of cardiomyocyte excitation-contraction coupling in the FVB/N-C57BL/6 intercrossed "chocolate" brown mice. TPS
46  2006 Gender disparity of streptozotocin-induced intrinsic contractile dysfunction in murine ventricular myocytes: role of chronic activation of Akt. SR, STZ
47  2006 High-dose benfotiamine rescues cardiomyocyte contractile dysfunction in streptozotocin-induced diabetes mellitus. AGE, SR, STZ, TR90
48  2006 High-fat diet-induced juvenile obesity leads to cardiomyocyte dysfunction and upregulation of Foxo3a transcription factor independent of lipotoxicity and apoptosis. NOS, Sir2, TPS, TR90
49  2006 Intermedin (adrenomedullin-2) enhances cardiac contractile function via a protein kinase C- and protein kinase A-dependent pathway in murine ventricular myocytes. CGRP, IMD
50  2006 Intracerebral hemorrhage elicits aberration in cardiomyocyte contractile function and intracellular Ca2+ transients. FFI, HIF-1alpha, IkappaB, TPS, TR90
51  2006 Leptin-induced suppression of cardiomyocyte contraction is amplified by ceramide. TPS, TR90
52  2006 Metallothionein alleviates cardiac dysfunction in streptozotocin-induced diabetes: role of Ca2+ cycling proteins, NADPH oxidase, poly(ADP-Ribose) polymerase and myosin heavy chain isozyme. MHC, MT, PARP, STZ, TPS
53  2006 Metallothionein antagonizes aging-induced cardiac contractile dysfunction: role of PTP1B, insulin receptor tyrosine phosphorylation and Akt. MT, PTP1B, TPS
54  2006 Paradoxical effects of ginkgolide B on cardiomyocyte contractile function in normal and high-glucose environments. HG, PLB, SERCA2a, TPS, TR90
55  2006 Sex difference in cardiomyocyte function in normal and metallothionein transgenic mice: the effect of diabetes mellitus. TR90
56  2005 Aging induces cardiac diastolic dysfunction, oxidative stress, accumulation of advanced glycation endproducts and protein modification. AGEs, TPS, TR90
57  2005 Bigendothelin-1 via p38-MAPK-dependent mechanism regulates adult rat ventricular myocyte contractility in sepsis. ARVM, p38 MAPK
58  2005 Doxorubicin induces cardiomyocyte dysfunction via a p38 MAP kinase-dependent oxidative stress mechanism. ROS, TPS
59  2005 Inhibition of PI-3 kinase/Akt/mTOR, but not calcineurin signaling, reverses insulin-like growth factor I-induced protection against glucose toxicity in cardiomyocyte contractile function. mTOR, TR90
60  2005 Inhibition of sarco(endo)plasmic reticulum Ca2+-ATPase differentially regulates contractile function in cardiac myocytes from normotensive and spontaneously hypertensive rats: role of Ca2+ regulatory proteins. CPA, endo, FFI, PLB, SHR, TPS, TR90, WKY
61  2005 Interaction between tumor necrosis factor-alpha and leptin-induced inhibition of cardiac contractile function in isolated ventricular myocytes. TNF-alpha, TPS
62  2005 Metallothionein alleviates cardiac contractile dysfunction induced by insulin resistance: role of Akt phosphorylation, PTB1B, PPARgamma and c-Jun. DeltaFFI
63  2004 Comparison of cardiac contractile and intracellular Ca2+ response between estrogen and phytoestrogen alpha-zearalanol in ventricular myocytes. TPS, TR90, ZAL
64  2004 Depressed contractile function and adrenergic responsiveness of cardiac myocytes in an experimental model of Parkinson disease, the MPTP-treated mouse. MPTP, SR, TPS, TR90
65  2004 Inhibition of cardiac myocyte contraction by 4-hydroxy-trans-2-nonenal. HNE
66  2004 Korean anti-inflammatory compound allergina enhances cardiac contractile function in isolated ventricular cardiomyocytes. TPS, TR90
67  2004 Phytoestrogenic isoflavones daidzein and genistein reduce glucose-toxicity-induced cardiac contractile dysfunction in ventricular myocytes. TPS, TR90
68  2004 Streptozotocin directly impairs cardiac contractile function in isolated ventricular myocytes via a p38 map kinase-dependent oxidative stress mechanism. STZ, TPS, TR90
69  2004 The cyclooxygenase-2 product prostaglandin E2 modulates cardiac contractile function in adult rat ventricular cardiomyocytes. TPS
70  2004 The oxygen radical generator pyrogallol impairs cardiomyocyte contractile function via a superoxide and p38 MAP kinase-dependent pathway: protection by anisodamine and tetramethylpyrazine. MAP, TMP, TPS
71  2004 Transgenic overexpression of insulin-like growth factor I prevents streptozotocin-induced cardiac contractile dysfunction and beta-adrenergic response in ventricular myocytes. IGF-I, STZ, TPS, TR90
72  2003 Acute exposure of ceramide enhances cardiac contractile function in isolated ventricular myocytes. CAPP, E-C, NO, PI, PKC
73  2003 AT1 blockade prevents glucose-induced cardiac dysfunction in ventricular myocytes: role of the AT1 receptor and NADPH oxidase. Ang, AT1, JAK2, TR90
74  2003 High glucose induces cardiac insulin-like growth factor I resistance in ventricular myocytes: role of Akt and ERK activation. TPS
75  2003 Impact of estrogen replacement on ventricular myocyte contractile function and protein kinase B/Akt activation. p-Akt, PLB, SERCA2a, sham
76  2003 Impaired cardiac function and IGF-I response in myocytes from calmodulin-diabetic mice: role of Akt and RhoA. PLB
77  2003 Influence of gender on intrinsic contractile properties of isolated ventricular myocytes from calmodulin-induced diabetic transgenic mice. TPS, TR90
78  2003 Influence of hypertension on cardiac contractile response of human erythrocyte-derived depressing factor in ventricular myocytes. EDDF, l-NAME, SHR, TPS, WKY
79  2003 Insulin resistance induces hyperleptinemia, cardiac contractile dysfunction but not cardiac leptin resistance in ventricular myocytes. TPS
80  2003 Iso-S-petasin, a hypotensive sesquiterpene from Petasites formosanus, depresses cardiac contraction and intracellular Ca2+ transients in adult rat ventricular myocytes. ---
81  2003 Japanese herbal medicine Toki-shakuyaku-san (TJ-23) enhances cardiac contractile function in isolated ventricular cardiomyocytes. TPS
82  2003 Paradoxical effects of pyruvate on cardiac contractile function under normal and high glucose in ventricular myocytes. HG, NG, TPS
83  2003 Tetramethylpyrazine elicits disparate responses in cardiac contraction and intracellular Ca(2+) transients in isolated adult rat ventricular myocytes. NOS, TMP, TPS
84  2002 Abrogated leptin-induced cardiac contractile response in ventricular myocytes under spontaneous hypertension: role of Jak/STAT pathway. JAK/STAT, L-NAME, MAP, NOS, SHR, WKY
85  2002 alpha2-Heremans Schmid glycoprotein, a putative inhibitor of tyrosine kinase, prevents glucose toxicity associated with cardiomyocyte dysfunction. TPS
86  2002 Anisodamine inhibits cardiac contraction and intracellular Ca(2+) transients in isolated adult rat ventricular myocytes. NOS, TPS
87  2002 Cardiac contractile function is enhanced in isolated ventricular myocytes from growth hormone transgenic mice. GH, TPS
88  2002 Ceramide attenuates high glucose-induced cardiac contractile abnormalities in cultured adult rat ventricular myocytes. FFI, PDMP, TPS, TR90
89  2002 Comparison of cardiac excitation-contraction coupling in isolated ventricular myocytes between rat and mouse. SD, TPS
90  2002 IGF-I attenuates diabetes-induced cardiac contractile dysfunction in ventricular myocytes. IGF-I, PLB, STZ, TPS
91  2002 Impaired cardiac excitation-contraction coupling in ventricular myocytes from Ames dwarf mice with IGF-I deficiency. CLs, E-C, GH, IGF-I, TPS
92  2002 Modulation of myocardial function by pyruvate. AT, tHR
93  2002 Prediabetic insulin resistance is not permissive to the development of cardiac resistance to insulin-like growth factor I in ventricular myocytes. ---
94  2002 Sepsis-induced depressed contractile function of isolated ventricular myocytes is due to altered calcium transient properties. TPS, TR90
95  2001 Characterization of contractile function in diabetic hypertensive cardiomyopathy in adult rat ventricular myocytes. SHR, STZ, TPS, TR90, WKY
96  2001 Ginsenosides Rb1 and Re decrease cardiac contraction in adult rat ventricular myocytes: role of nitric oxide. NOS, TPS, TR90
97  2001 Influence of ovariectomy on ventricular myocyte contraction in simulated diabetes. HG, NOS, SHAM, TR90
98  2001 Isolated ventricular myocytes from copper-deficient rat hearts exhibit enhanced contractile function. TPS, TR90
99  2001 Loss of cardiac contractile response to tetrahydropapaveroline with advanced age and hypertension. PTD, THP, TPT/TPS
100  2001 Prenatal ethanol exposure alters ventricular myocyte contractile function in the offspring of rats: influence of maternal Mg2+ supplementation. FAS, TR90