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[Related PubMed/MEDLINE] Total Number of Papers: 40
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Abbreviation |
: PXR |
Long Form |
: pregnane xenobiotic receptor |
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No. |
Year |
Title |
Co-occurring Abbreviation |
1 |
2021 |
Designing Out PXR Activity on Drug Discovery Projects: A Review of Structure-Based Methods, Empirical and Computational Approaches. |
--- |
2 |
2021 |
In Vivo Induction of P-Glycoprotein Function can be Measured with [18F]MC225 and PET. |
BBB, P-gp, PET, VT |
3 |
2021 |
Polychlorinated biphenyls altered gut microbiome in CAR and PXR knockout mice exhibiting toxicant-associated steatohepatitis. |
CAR, NAFLD, PCBs |
4 |
2020 |
Effect of P-glycoprotein (P-gp) Inducers on Exposure of P-gp Substrates: Review of Clinical Drug-Drug Interaction Studies. |
CAR, CYP450, DDIs, P-gp, PK |
5 |
2020 |
Smallest Maximum Intramolecular Distance: A Novel Method to Mitigate Pregnane Xenobiotic Receptor Activation. |
SMID |
6 |
2019 |
A comprehensive evaluation of anti-diabetic drugs on nuclear receptor PXR platform. |
DDIs, DMD |
7 |
2018 |
Cytochrome P450 3A Induction Predicts P-glycoprotein Induction; Part 1: Establishing Induction Relationships Using Ascending Dose Rifampin. |
BCRP, OATP, P-gp |
8 |
2018 |
Stable cellular models of nuclear receptor PXR for high-throughput evaluation of small molecules. |
--- |
9 |
2017 |
Heterodimerization of Retinoid X Receptor with Xenobiotic Receptor partners occurs in the cytoplasmic compartment: Mechanistic insights of events in living cells. |
CAR, NLS, RXR |
10 |
2017 |
Influence of a critical single nucleotide polymorphism on nuclear receptor PXR-promoter function. |
EMSA, IBD |
11 |
2016 |
A comprehensive analysis and functional characterization of naturally occurring non-synonymous variants of nuclear receptor PXR. |
CYP450 |
12 |
2016 |
Nuclear receptors and nonalcoholic fatty liver disease. |
CAR, FXR, LXR, NAFLD, PPARs, RXR |
13 |
2015 |
EFFECT OF PREGNANE XENOBIOTIC RECEPTOR ACTIVATION ON INFLAMMATORY BOWEL DISEASE TREATED WITH RIFAXIMIN. |
IBD |
14 |
2015 |
Identification and interplay of sequence specific DNA binding proteins involved in regulation of human Pregnane and Xenobiotic Receptor gene. |
CE, hnRNP K |
15 |
2015 |
Transcription regulation of nuclear receptor PXR: Role of SUMO-1 modification and NDSM in receptor function. |
--- |
16 |
2014 |
Cytochrome P450 enzyme mediated herbal drug interactions (Part 1). |
--- |
17 |
2014 |
Human receptor activation by aroclor 1260, a polychlorinated biphenyl mixture. |
AhR, CAR, FXR, NAFLD, PCBs, PPARs |
18 |
2014 |
Involvement of pregnane xenobiotic receptor in mating-induced allopregnanolone formation in the midbrain and hippocampus and brain-derived neurotrophic factor in the hippocampus among female rats. |
AS-ODNs, BDNF |
19 |
2014 |
Novel receptor targets for production and action of allopregnanolone in the central nervous system: a focus on pregnane xenobiotic receptor. |
VTA |
20 |
2014 |
Role of pregnane xenobiotic receptor in the midbrain ventral tegmental area for estradiol- and 3alpha,5alpha-THP-facilitated lordosis of female rats. |
VTA |
21 |
2014 |
The pregnane xenobiotic receptor, a prominent liver factor, has actions in the midbrain for neurosteroid synthesis and behavioral/neural plasticity of female rats. |
3alpha,5alpha-THP, AS-ODNs, TSPO, VTA |
22 |
2013 |
High-throughput evaluation method for drug association with pregnane X receptor (PXR) using differential scanning fluorometry. |
DSC, DSF |
23 |
2013 |
Motivated behaviors and levels of 3alpha,5alpha-THP in the midbrain are attenuated by knocking down expression of pregnane xenobiotic receptor in the midbrain ventral tegmental area of proestrous rats. |
AS-ODNs, DHP, VTA |
24 |
2013 |
Pregnane xenobiotic receptors and membrane progestin receptors: role in neurosteroid-mediated motivated behaviours. |
mPRs, VTA |
25 |
2012 |
Effects and Mechanisms of 3alpha,5alpha,-THP on Emotion, Motivation, and Reward Functions Involving Pregnane Xenobiotic Receptor. |
VTA |
26 |
2012 |
Pregnane xenobiotic receptor in cancer pathogenesis and therapeutic response. |
--- |
27 |
2012 |
Sulforaphane is not an effective antagonist of the human pregnane X-receptor in vivo. |
SFN |
28 |
2010 |
Cross-talk between androgen receptor and pregnane and xenobiotic receptor reveals existence of a novel modulatory action of anti-androgenic drugs. |
AR, NRs |
29 |
2010 |
Endocrine disruptors provoke differential modulatory responses on androgen receptor and pregnane and xenobiotic receptor: potential implications in metabolic disorders. |
AR, EDs |
30 |
2010 |
Evaluation of liver and thyroid toxicity in Sprague-Dawley rats after exposure to polybrominated diphenyl ether BDE-209. |
CAR, PBDE, PND |
31 |
2009 |
Association of pregnane X receptor with multidrug resistance-related protein 3 and its role in human colon cancer chemoresistance. |
mRNA, MRP3 |
32 |
2009 |
Constitutive androstane receptor mediates the induction of drug metabolism in mouse models of type 1 diabetes. |
CAR, PGC |
33 |
2008 |
ABC transporters, cytochromes P450 and their main transcription factors: expression at the human blood-brain barrier. |
ABC, AhR, BBB, BCRP, CAR, NG2 |
34 |
2008 |
Dexamethasone increases expression and activity of multidrug resistance transporters at the rat blood-brain barrier. |
GR, MDR |
35 |
2008 |
Nutritional calcium modulates colonic expression of vitamin D receptor and pregnane X receptor target genes. |
CYP3A11, SXR |
36 |
2007 |
(Far) Outside the box: genomic approach to acute porphyria. |
CAR, GH, GR, HNF-4, PGC-1alpha |
37 |
2007 |
Expression levels and activation of a PXR variant are directly related to drug resistance in osteosarcoma cell lines. |
BFC, PCR |
38 |
2006 |
Induction of human UDP-glucuronosyltransferase 1A1 by cortisol-GR. |
GR |
39 |
2005 |
Pregnane and Xenobiotic Receptor (PXR/SXR) resides predominantly in the nuclear compartment of the interphase cell and associates with the condensed chromosomes during mitosis. |
--- |
40 |
2005 |
Purification of full-length human pregnane and xenobiotic receptor: polyclonal antibody preparation for immunological characterization. |
--- |
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