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Abbreviation : RPPA
Long Form : reverse phase protein array
No. Year Title Co-occurring Abbreviation
2020 CCNE1 and BRD4 co-amplification in high-grade serous ovarian cancer is associated with poor clinical outcomes. BRD4, CCNE1, HGSOC, IHC, TMA
2020 Cisplatin in Combination with MDM2 Inhibition Downregulates Rad51 Recombinase in a Bimodal Manner to Inhibit Homologous Recombination and Augment Tumor Cell Kill. HR, IPA
2020 Combination of PI3K and MEK inhibitors yields durable remission in PDX models of PIK3CA-mutated metaplastic breast cancers. MBC, NGS, PDXs, TNBCs
2020 Differential Targeting of Gr-MDSCs, T Cells and Prostate Cancer Cells by Dactolisib and Dasatinib. CRPC, Gr-MDSCs, ICB
2020 Discovering Therapeutic Protein Targets for Bladder Cancer Using Proteomic Data Analysis. ACVRL1, CDH2, EGFR, GO, HSP60, iTRAQ, KDR, PANTHER, TFRC
2020 Identification and clinical impact of potentially actionable somatic oncogenic mutations in solid tumor samples. ---
2020 Protein tyrosine phosphatase 4A3 (PTP4A3/PRL-3) drives migration and progression of T-cell acute lymphoblastic leukemia in vitro and in vivo. GSEA, shRNA, T-ALL
2020 Quantification of Biomarker Proteins Using Reverse-Phase Protein Arrays. ---
2020 Quantification of biomarkers for beef meat qualities using a combination of Parallel Reaction Monitoring- and antibody-based proteomics. PRM
10  2020 Sirtuin 1 regulates mitochondrial function and immune homeostasis in respiratory syncytial virus infected dendritic cells. BMDC, OCR, ROS, RSV, SIRT1
11  2020 The high protein expression of FOXO3, but not that of FOXO1, is associated with markers of good prognosis. DDR
12  2020 The impact of ultraviolet- and infrared-based laser microdissection technology on phosphoprotein detection in the laser microdissection-reverse phase protein array workflow. IR LCM, UV LMD
13  2020 TP53/miR-34a-associated signaling targets SERPINE1 expression in human pancreatic cancer. BBR, PDAC
14  2020 Utility of a Reverse Phase Protein Array to Evaluate Multiple Biomarkers in Diffuse Large B-Cell Lymphoma. DLBCL, IHC, ROC
15  2020 Verteporfin induced SUMOylation of YAP1 in endometrial cancer. EC, IPA, TEAD
16  2019 A Bayesian random partition model for sequential refinement and coagulation. ---
17  2019 A CTC-Cluster-Specific Signature Derived from OMICS Analysis of Patient-Derived Xenograft Tumors Predicts Outcomes in Basal-Like Breast Cancer. ACC1, BC, CTCcl, EMT, FC, FDR, IHC, NES, TNBC PDX
18  2019 Analytical Platforms 3: Processing Samples via the RPPA Pipeline to Generate Large-Scale Data for Clinical Studies. ---
19  2019 Antibody Screening. ---
20  2019 Antitumor effect of insulin-like growth factor-1 receptor inhibition in head and neck squamous cell carcinoma. HER3, HNSCC, IGF1R, OC, TKIs
21  2019 CGRRF1, a growth suppressor, regulates EGFR ubiquitination in breast cancer. qRT-PCR
22  2019 Clusterin enhances AKT2-mediated motility of normal and cancer prostate cells through a PTEN and PHLPP1 circuit. CLU, PC3, PI3K, PNT1A, PTEN
23  2019 Combining the "Sibling Technologies" of Laser Capture Microdissection and Reverse Phase Protein Microarrays. LCM
24  2019 Comprehensive analysis of Reverse Phase Protein Array data reveals characteristic unique proteomic signatures for glioblastoma subtypes. ECM, GBM
25  2019 Discovery and Therapeutic Exploitation of Mechanisms of Resistance to MET Inhibitors in Glioblastoma. GBM
26  2019 Drug Screening Platforms and RPPA. ---
27  2019 Fast approximate inference for variable selection in Dirichlet process mixtures, with an application to pan-cancer proteomics. BMA, BMS, DP, SUGS
28  2019 Generation of Raw RPPA Data and Their Conversion to Analysis-Ready Data. ---
29  2019 High OGT activity is essential for MYC-driven proliferation of prostate cancer cells. ChIP, HCF-1, OGT, SE, Seq
30  2019 High Precision RPPA: Concept, Features, and Application Performance of the Integrated Zeptosens Platform. ---
31  2019 Identification and validation of a prognostic proteomic signature for cervical cancer. ICC, RSF, SAAs
32  2019 Implementing Reverse Phase Protein Array Profiling as a Sensitive Method for the Early Pre-Clinical Detection of Off-Target Toxicities Associated with Sunitinib Malate. TKI
33  2019 LGALS3 is connected to CD74 in a previously unknown protein network that is associated with poor survival in patients with AML. AML
34  2019 Mauritian Endemic Medicinal Plant Extracts Induce G2/M Phase Cell Cycle Arrest and Growth Inhibition of Oesophageal Squamous Cell Carcinoma in Vitro. AMPK, GC-MS
35  2019 MicroRNA-509-3p inhibits cellular migration, invasion, and proliferation, and sensitizes osteosarcoma to cisplatin. OS
36  2019 O-GlcNAc Transferase Inhibition Differentially Affects Breast Cancer Subtypes. Hes1, OGT, TNBC
37  2019 Phase II trial of AKT inhibitor MK-2206 in patients with advanced breast cancer who have tumors with PIK3CA or AKT mutations, and/or PTEN loss/PTEN mutation. ORR, PBMC, PRP
38  2019 Reconstruction of Different Modes of WNT Dependent Protein Networks from Time Series Protein Quantification. ---
39  2019 Reproducibility and Crossplatform Validation of Reverse-Phase Protein Array Data. ---
40  2019 RPPAs for Cell Subpopulation Analysis. CoLA, DTPs
41  2019 Solid Pin Protein Array Printing Platforms. ---
42  2019 Super-Enhancer-Associated LncRNA UCA1 Interacts Directly with AMOT to Activate YAP Target Genes in Epithelial Ovarian Cancer. Amot, iRAP, lncRNAs, UCA1
43  2019 Suppression of Nuclear Factor-kappaB by Glucocorticoid Receptor Blocks Estrogen-Induced Apoptosis in Estrogen-Deprived Breast Cancer Cells. FADS1, GR, IRE1alpha, LTED, NF-kappaB, PERK
44  2019 Targeting cyclin-dependent kinase 9 by a novel inhibitor enhances radiosensitization and identifies Axl as a novel downstream target in esophageal adenocarcinoma. CDK9, PDX
45  2019 The kinase inhibitor SI113 induces autophagy and synergizes with quinacrine in hindering the growth of human glioblastoma multiforme cells. GBM
46  2019 Topological integration of RPPA proteomic data with multi-omics data for survival prediction in breast cancer via pathway activity inference. iDRW, RWR
47  2019 Tyrosine Threonine Kinase Inhibition Eliminates Lung Cancers by Augmenting Apoptosis and Polyploidy. ---
48  2019 UCHL1 loss alters the cell-cycle in metastatic pancreatic neuroendocrine tumors. PNET, UCHL1
49  2019 Using Reverse Phase Protein Array (RPPA) to Identify and Target Adaptive Resistance. ---
50  2019 Utility of Reverse-Phase Protein Array for Refining Precision Oncology. ---
51  2018 BCL2 Regulation according to Molecular Subtype of Breast Cancer by Analysis of The Cancer Genome Atlas Database. Bcl-2, HER2
52  2018 Beef tenderness and intramuscular fat proteomic biomarkers: muscle type effect. ALDH1A1, ALDOA, CRYAB, ENO3, FHL1, LT, MyHC-IIX, RA, SM, ST, TB, TPI1
53  2018 CHK1-targeted therapy to deplete DNA replication-stressed, p53-deficient, hyperdiploid colorectal cancer stem cells. ATM, Chk, CRC, CRC-SCs, CSCs, RS
54  2018 Credentialing Individual Samples for Proteogenomic Analysis. PMC
55  2018 E-cadherin loss induces targetable autocrine activation of growth factor signalling in lobular breast cancer. GFR, ILC, PI3K
56  2018 EB-3D a novel choline kinase inhibitor induces deregulation of the AMPK-mTOR pathway and apoptosis in leukemia T-cells. ChoKalpha1, T-ALL
57  2018 Enteral Arg-Gln Dipeptide Administration Increases Retinal Docosahexaenoic Acid and Neuroprotectin D1 in a Murine Model of Retinopathy of Prematurity. Arg-Glu, DHA, LCPUFA, OIR, ROP
58  2018 Frequent HPV-independent p16/INK4A overexpression in head and neck cancer. HNSCC, HPV
59  2018 Global proteomics profiling improves drug sensitivity prediction: results from a multi-omics, pan-cancer modeling approach. MS
60  2018 Histone Modification Patterns Using RPPA-Based Profiling Predict Outcome in Acute Myeloid Leukemia Patients. AML, HMP
61  2018 Induction ofnerve growth factor byphorbol 12-myristate 13-acetate is dependent upon the mitogen activated protein kinase pathway. NGF, PMA
62  2018 Integrative proteomic and transcriptomic analysis provides evidence for TrkB (NTRK2) as a therapeutic target in combination with tyrosine kinase inhibitors for non-small cell lung cancer. ACA, SCC
63  2018 Nephronectin mediates p38 MAPK-induced cell viability via its integrin-binding enhancer motif. ECM, MAPK, Npnt
64  2018 Network proteomics of human dermal wound healing. ---
65  2018 Phosphoproteomic analysis reveals Smad protein family activation following Rift Valley fever virus infection. IL1R2, RVFV
66  2018 PI3K: A master regulator of brain metastasis-promoting macrophages/microglia. CNS, OS
67  2018 Preclinical evaluation and reverse phase protein Array-based profiling of PI3K and MEK inhibitors in endometrial carcinoma in vitro. EC, PI3K
68  2018 Proteomic Profiling of Iron-Treated Ovarian Cells Identifies AKT Activation that Modulates the CLEAR Network. CLEAR, IPA, MITF, TFEB
69  2018 RAD50 Expression Is Associated with Poor Clinical Outcomes after Radiotherapy for Resected Non-small Cell Lung Cancer. NSCLC, TMA
70  2018 Renal cancer: new models and approach for personalizing therapy. ccRCC
71  2018 Reverse Phase Protein array for the quantification and validation of protein biomarkers of beef qualities: The case of meat color from Charolais breed. FHL1, TRIM72
72  2018 Reverse phase protein arrays for the identification/validation of biomarkers of beef texture and their use for early classification of carcasses. FHL1, TRIM72
73  2018 Ribociclib, a Cdk4/Cdk6 kinase inhibitor, enhances glucocorticoid sensitivity in B-acute lymphoblastic leukemia (B-All). B-ALL, BALL, GR
74  2018 Role of MSC-derived galectin 3 in the AML microenvironment. AML, ITGB3, MSC
75  2018 RPPAware: A software suite to preprocess, analyze and visualize reverse phase protein array data. ---
76  2018 The impact on high-grade serous ovarian cancer of obesity and lipid metabolism-related gene expression patterns: the underestimated driving force affecting prognosis. HGOSC, ICGC
77  2018 Use of dual mTOR inhibitor MLN0128 against everolimus-resistant breast cancer. RAD-R
78  2017 5-Aminolevulinic Acid Guided Sampling of Glioblastoma Microenvironments Identifies Pro-Survival Signaling at Infiltrative Margins. GBM, TMEs
79  2017 A Population of Heterogeneous Breast Cancer Patient-Derived Xenografts Demonstrate Broad Activity of PARP Inhibitor in BRCA1/2 Wild-Type Tumors. PDX, TNBC
80  2017 A preclinical evaluation of the MEK inhibitor refametinib in HER2-positive breast cancer cell lines including those with acquired resistance to trastuzumab or lapatinib. MEKi, PI3Ki
81  2017 Akt Activation Mediates Acquired Resistance to Fibroblast Growth Factor Receptor Inhibitor BGJ398. ---
82  2017 Cathepsin G Is Expressed by Acute Lymphoblastic Leukemia and Is a Potential Immunotherapeutic Target. ALL, AML, CG
83  2017 Characterization of patient-derived tumor xenografts (PDXs) as models for estrogen receptor positive (ER+HER2- and ER+HER2+) breast cancers. PDXs
84  2017 Clustering and Network Analysis of Reverse Phase Protein Array Data. ---
85  2017 Colony Lysate Arrays for Proteomic Profiling of Drug-Tolerant Persisters of Cancer Cell. CoLA, DTPs
86  2017 Defining the Na+/H+ exchanger NHE1 interactome in triple-negative breast cancer cells. ---
87  2017 Effects of low dose ionizing radiation on DNA damage-caused pathways by reverse-phase protein array and Bayesian networks. AT, ATM, DNA, DST, IR, PPIs
88  2017 Enrichment of PI3K-AKT-mTOR Pathway Activation in Hepatic Metastases from Breast Cancer. ---
89  2017 Explore, Visualize, and Analyze Functional Cancer Proteomic Data Using the Cancer Proteome Atlas. ---
90  2017 Expression of Iron-Related Proteins Differentiate Non-Cancerous and Cancerous Breast Tumors. BMP6, CD74, ELISA, FPN, FTH, FTL, HMGB1, INHA, MyD88, STAT3, STAT5, TFRC
91  2017 FUSION-Guided Hypothesis Development Leads to the Identification of N⁶,N⁶-Dimethyladenosine, a Marine-Derived AKT Pathway Inhibitor. FUSION
92  2017 How may targeted proteomics complement genomic data in breast cancer? BC, MS
93  2017 Increased MAPK1/3 Phosphorylation in Luminal Breast Cancer Related with PIK3CA Hotspot Mutations and Prognosis. LNN, TMA
94  2017 Low expression of ASH2L protein correlates with a favorable outcome in acute myeloid leukemia. FLT3, MLL
95  2017 Multifaceted Role of BTLA in the Control of CD8+ T-cell Fate after Antigen Encounter. BTLA, PDX, TIL
96  2017 Multiple-response regression analysis links magnetic resonance imaging features to de-regulated protein expression and pathway activity in lower grade glioma. LGGs
97  2017 Novel biomarkers of nasopharyngeal carcinoma metastasis risk identified by reverse phase protein array based tumor profiling with consideration of plasma Epstein-Barr virus DNA load. EBV, NPC
98  2017 Overcoming intratumoural heterogeneity for reproducible molecular risk stratification: a case study in advanced kidney cancer. HR, ITH, mccRCC, NEAT
99  2017 Protein Arrays III: Reverse-Phase Protein Arrays. CSA, NIR
100  2017 Protein network construction using reverse phase protein array data. ---