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Abbreviation : RTX
Long Form : resiniferatoxin
No. Year Title Co-occurring Abbreviation
2020 Cardiac TRPV1 afferent signaling promotes arrhythmogenic ventricular remodeling after myocardial infarction. MI, SGNs, TRPV1, VAs
2020 Involvement of TRPV1 and the efficacy of alpha-spinasterol on experimental fibromyalgia symptoms in mice. Imax, s.c, TRPV1
2020 Perineural application of resiniferatoxin on uninjured L3 and L4 nerves completely alleviates thermal and mechanical hypersensitivity following L5 nerve injury in rats. DRG
2020 Ultra-low doses of the transient receptor potential vanilloid 1 agonist, resiniferatoxin, prevents vomiting evoked by diverse emetogens in the least shrew (Cryptotis parva). Delta-THC, SERCA, TRPV1
2019 A sensitive bioanalytical method for quantitative determination of resiniferatoxin in rat plasma using ultra-high performance liquid chromatography coupled to tandem mass spectrometry and its application in pharmacokinetic study. MRM, TRPV1
2019 Cardiac Afferent Denervation Abolishes Ganglionated Plexi and Sympathetic Responses to Apnea: Implications for Atrial Fibrillation. AF, GP, TRPV1
2019 Conserved allosteric pathways for activation of TRPV3 revealed through engineering vanilloid-sensitivity. ---
2019 Deep Sequencing Identification of Differentially Expressed miRNAs in the Spinal Cord of Resiniferatoxin-Treated Rats in Response to Electroacupuncture. EA
2019 Distribution, Morphological Characterization, and Resiniferatoxin-Susceptibility of Sensory Neurons That Innervate Rat Perirenal Adipose Tissue. DRG, PrAT, TRPV1
10  2019 Effects of early intravesical administration of resiniferatoxin to spinal cord-injured rats in neurogenic detrusor overactivity. NDO, TRPV1
11  2019 Effects of the combination of vibegron and imidafenacin on bladder function in urethane-anesthetized rats. ---
12  2019 Electroacupuncture decreases Netrin-1-induced myelinated afferent fiber sprouting and neuropathic pain through mu-opioid receptors. beta-FNA, CTB, EA, nor-BNI, PHN
13  2019 Estrogenic, Antiestrogenic and Antiproliferative Activities of Euphorbia bicolor (Euphorbiaceae) Latex Extracts and Its Phytochemicals. ---
14  2019 Focal selective chemo-ablation of spinal cardiac afferent nerve by resiniferatoxin protects the heart from pressure overload-induced hypertrophy. CSNAs, TAC, TRPV1
15  2019 Lactobacillus reuteri DSM 17938 Protects against Gastric Damage Induced by Ethanol Administration in Mice: Role of TRPV1/Substance P Axis. MDA, SP, TRPV1
16  2019 Selective chemical ablation of transient receptor potential vanilloid 1 expressing neurons in the left stellate ganglion protects against ischemia-induced ventricular arrhythmias in dogs. AMI, APD, APDA, BVR, ERP, HRV, LSG, NE, NGF, Tp-Te, VAs, VFT
17  2019 Symmetry transitions during gating of the TRPV2 ion channel in lipid membranes. cryo-EM, TRPV2
18  2019 Transient Receptor Potential Vanilloid 1 Modulates Central Inflammation in Multiple Sclerosis. 5-IRTX, CSF, IL, MS, SNP, TNF, TRPV1
19  2019 Treatment with methyl-beta-cyclodextrin prevents mechanical allodynia in resiniferatoxin neuropathy in a mouse model. MbetaC, PAP, TRPV1
20  2019 TRPV1 (Transient Receptor Potential Vanilloid 1) Cardiac Spinal Afferents Contribute to Hypertension in Spontaneous Hypertensive Rat. BP, SHRs, TRPV1
21  2018 Cardiac vanilloid receptor-1 afferent depletion enhances stellate ganglion neuronal activity and efferent sympathetic response to cardiac stress. RVP, SGNs, VR1
22  2018 Conformational plasticity in the selectivity filter of the TRPV2 ion channel. TRPV
23  2018 Distinct TrkA and Ret modulated negative and positive neuropathic behaviors in a mouse model of resiniferatoxin-induced small fiber neuropathy. 4-MC, ATF3, DRG
24  2018 Downregulation of adenosine and adenosine A1 receptor contributes to neuropathic pain in resiniferatoxin neuropathy. A1Rs, DRG, i.t, PAP, TRPV1
25  2018 Effect of Tetrodotoxin Pellets in a Rat Model of Postherpetic Neuralgia. PHN, TTX
26  2018 Establishing a Mouse Model of a Pure Small Fiber Neuropathy with the Ultrapotent Agonist of Transient Receptor Potential Vanilloid Type 1. DM, IENF, TRPV1
27  2018 Expression of functional TRPV1 receptor in primary culture of canine keratinocytes. 5-I-RTX, TRPV1
28  2018 Long-term pain relief in canine osteoarthritis by a single intra-articular injection of resiniferatoxin, a potent TRPV1 agonist. ---
29  2018 Neuropeptides SP and CGRP Underlie the Electrical Properties of Acupoints. CGRP, EBD, SP
30  2018 Pain control through selective chemo-axotomy of centrally projecting TRPV1+ sensory neurons. TRPV1
31  2018 Regulatory role of capsaicin-sensitive peptidergic sensory nerves in the proteoglycan-induced autoimmune arthritis model of the mouse. PGIA
32  2018 Selective ablation of TRPV1 by intrathecal injection of resiniferatoxin in rats increases renal sympathoexcitatory responses and salt sensitivity. MAP, TRPV1
33  2018 Target engagement and histopathology of neuraxial resiniferatoxin in dog. DRGs, i.c, SPIR
34  2018 Tumor necrosis factor-alpha mediated pain hypersensitivity through Ret receptor in resiniferatoxin neuropathy. SFN, TNF-alpha, TNFR1
35  2018 [Stimulating Frequency-dependent Analgesic Effect of Electroacupuncture via Down-regulating Expression of VEGF in Dorsal Horns of Lumbar Spinal Cord in Post Herpetic Neuralgia Rats]. DHs, EA, PHN, PT, qPCR, VEGF
36  2017 Antiallodynic effect of intrathecal resiniferatoxin on neuropathic pain model of chronic constriction injury. CCI, DRG, PRE, TRPV1
37  2017 Chronic stress-induced mechanical hyperalgesia is controlled by capsaicin-sensitive neurones in the mouse. CRS
38  2017 Effects of small-fiber neuropathy induced by resiniferatoxin on skin healing and axonal regrowth after burn. ---
39  2017 Inhibitory effects of retigabine, a Kv7 channel activator, on mechanosensitive primary bladder afferent activities and nociceptive behaviors in rats. RBCs, SAAs
40  2017 Intraluminal Administration of Resiniferatoxin Protects against Clostridium difficile Toxin A-Induced Colitis. ---
41  2017 Intrathecal Resiniferatoxin Modulates TRPV1 in DRG Neurons and Reduces TNF-Induced Pain-Related Behavior. TRPV1
42  2017 Intravesical treatment for interstitial cystitis/painful bladder syndrome: a network meta-analysis. BCG, BoNTA, CS, GRA, IC/PBS, PPS
43  2017 Local Resiniferatoxin Induces Long-Lasting Analgesia in a Rat Model of Full Thickness Thermal Injury. TRPV1
44  2017 Molecular Surgery Concept from Bench to Bedside: A Focus on TRPV1+ Pain-Sensing Neurons. ---
45  2017 Novel Radiolabeled Vanilloid with Enhanced Specificity for Human Transient Receptor Potential Vanilloid 1 (TRPV1). TRPV1
46  2017 Participation of central GABAA receptors in the trigeminal processing of mechanical allodynia in rats. GABAA, IL-1beta
47  2017 Role of peripheral and central TRPV1 receptors in facial heat hyperalgesia in streptozotocin-induced diabetic rats. ---
48  2017 Supraspinal-selective TRPV1 desensitization induced by intracerebroventricular treatment with resiniferatoxin. i.c.v, TRPV1
49  2017 The Influence of Resiniferatoxin (RTX) and Tetrodotoxin (TTX) on the Distribution, Relative Frequency, and Chemical Coding of Noradrenergic and Cholinergic Nerve Fibers Supplying the Porcine Urinary Bladder Wall. CGRP, NF, TTX, VIP
50  2017 Therapeutic Effects of Resiniferatoxin Related with Immunological Responses for Intestinal Inflammation in Trichinellosis. GC
51  2016 Activated Glia Increased the Level of Proinflammatory Cytokines in a Resiniferatoxin-Induced Neuropathic Pain Rat Model. NR2B
52  2016 Capsaicin-Sensitive Sensory Nerves Mediate the Cellular and Microvascular Effects of H2S via TRPA1 Receptor Activation and Neuropeptide Release. AITC, TRG
53  2016 Characterization of muscarinic and P2X receptors in the urothelium and detrusor muscle of the rat bladder. CYP
54  2016 Detailed Analysis of the Binding Mode of Vanilloids to Transient Receptor Potential Vanilloid Type I (TRPV1) by a Mutational and Computational Study. TRPV1
55  2016 Engineering vanilloid-sensitivity into the rat TRPV2 channel. ---
56  2016 EXPRESS: NGF-trkA signaling modulates the analgesic effects of prostatic acid phosphatase in resiniferatoxin-induced neuropathy. 4-MC, ATF3, NGF, PAP
57  2016 Netrin-1 Contributes to Myelinated Afferent Fiber Sprouting and Neuropathic Pain. DCC
58  2016 Resiniferatoxin: The Evolution of the "Molecular Scalpel" for Chronic Pain Relief. TRPV1
59  2016 Role of capsaicin-sensitive nerves and tachykinins in mast cell tryptase-induced inflammation of murine knees. MCT, NKA, SP, TRPV1
60  2016 The effect of intra-articular vanilloid receptor agonists on pain behavior measures in a murine model of acute monoarthritis. CAP, DWB, EPS, IA
61  2016 The Effect of Treatment with Resiniferatoxin and Capsaicin on Dynamic Weight Bearing Measures and Evoked Pain Responses in a Chronic Inflammatory Arthritis Murine Model. ADWB, CAP, CFA, EPS, IA
62  2016 The effects of intra-articular resiniferatoxin on monosodium iodoacetate-induced osteoarthritic pain in rats. CGRP, OA, TRPV1
63  2016 The influence of resiniferatoxin on the chemical coding of caudal mesenteric ganglion neurons supplying the urinary bladder in the pig. CaMG, CB, FB, GAL, nNOS, NPY, SOM, TH, VIP
64  2016 The preventive effect of resiniferatoxin on the development of cold hypersensitivity induced by spinal nerve ligation: involvement of TRPM8. DRG, SNL, TRP, TRPA, TRPM
65  2016 The Role of C Fibers in Spinal Microglia Induction and Possible Relation with TRPV3 Expression During Chronic Inflammatory Arthritis in Rats. CFA, FKN, TRPV1
66  2016 TRPV1 is crucial for proinflammatory STAT3 signaling and thermoregulation-associated pathways in the brain during inflammation. CVOs, i.c.v, LPS, STAT3, TRPV1
67  2016 TRPV1: A Target for Rational Drug Design. TRPV1
68  2016 TRPV4 mediates afferent pathways in the urinary bladder. A spinal c-fos study showing TRPV1 related adaptations in the TRPV4 knockout mouse. LPS, TRPV4
69  2016 Understanding TRPV1 activation by ligands: Insights from the binding modes of capsaicin and resiniferatoxin. CAPS, TRPV1
70  2016 Vanilloid Receptor 1 Agonists, Capsaicin and Resiniferatoxin, Enhance MHC Class I-restricted Viral Antigen Presentation in Virus-infected Dendritic Cells. BMDCs, CP, DCs, VR1
71  2015 Capsaicin-sensitive sensory nerves exert complex regulatory functions in the serum-transfer mouse model of autoimmune arthritis. MMP, MPO
72  2015 CT-guided injection of a TRPV1 agonist around dorsal root ganglia decreases pain transmission in swine. CT, DRG
73  2015 Evidence for Novel Pharmacological Sensitivities of Transient Receptor Potential (TRP) Channels in Schistosoma mansoni. PZQ, TRP
74  2015 Expression and functionality of TRPV1 receptor in human MCF-7 and canine CF.41 cells. 5-I-RTX, CMT, TRPV1
75  2015 Genesis of anxiety, depression, and ongoing abdominal discomfort in ulcerative colitis-like colon inflammation. CPP, DRG, DSS, TRPV1
76  2015 Influence of urethane-anesthesia on the effect of resiniferatoxin treatment on bladder function in rats with spinal cord injury. LUT, NVCs, SCI
77  2015 Intrathecal resiniferatoxin in a dog model: efficacy in bone cancer pain. TRPV1
78  2015 Mechanisms inducing autonomic dysreflexia during urinary bladder distention in rats with spinal cord injury. NGF, SCI, SI
79  2015 Open-loop characteristics of the arterial baroreflex after blockade of unmyelinated baroreceptors with resiniferatoxin. AP, BRP, SNA
80  2015 Pelvic organ cross-sensitization to enhance bladder and urethral pain behaviors in rats with experimental colitis. BPS/IC, DRG, IBS, MPO, TNBS, TRPV1
81  2015 Role of the outer pore domain in transient receptor potential vanilloid 1 dynamic permeability to large cations. NMDG, TRPV1
82  2015 The effect of clonidine pretreatment on epidural resiniferatoxin in a neuropathic pain rat model. ---
83  2015 The influence of intravesical administration of resiniferatoxin (RTX) on the chemical coding of sympathetic chain ganglia (SChG) neurons supplying the porcine urinary bladder. nNOS, NPY, SChG, SOM, VIP
84  2014 A reversible functional sensory neuropathy model. CGRP, DRG, IENFs, SP
85  2014 Activation of the TRPV1 cation channel contributes to stress-induced astrocyte migration. CAP, CPZ, IRTX, TRPV1
86  2014 Additive antiemetic efficacy of low-doses of the cannabinoid CB(1/2) receptor agonist Delta(9)-THC with ultralow-doses of the vanilloid TRPV1 receptor agonist resiniferatoxin in the least shrew (Cryptotis parva). i.p, s.c
87  2014 Depressive behavior in the forced swim test can be induced by TRPV1 receptor activity and is dependent on NMDA receptors. TRPV1
88  2014 Differential regulation of peripheral IL-1beta-induced mechanical allodynia and thermal hyperalgesia in rats. AMPA, CGRP, IL, IRTX, NF200, NMDA, NR1, PKA, PKC, TRPV1
89  2014 Intraganglionar resiniferatoxin prevents orofacial inflammatory and neuropathic hyperalgesia. TRPV1
90  2014 Nociception and inflammatory hyperalgesia evaluated in rodents using infrared laser stimulation after Trpv1 gene knockout or resiniferatoxin lesion. ---
91  2014 Plasma somatostatin-like immunoreactivity increases in the plasma of septic patients and rats with systemic inflammatory reaction: experimental evidence for its sensory origin and protective role. c-SOM, CLP, SIRS, SST-LI
92  2014 Pro-inflammatory cytokines in paraventricular nucleus mediate the cardiac sympathetic afferent reflex in hypertension. AIC, Ang, BK, CSAR, IL, MAP, PIC, RSNA, SHR, TNF, WKY
93  2014 Resiniferatoxin induces death of bladder cancer cells associated with mitochondrial dysfunction and reduces tumor growth in a xenograft mouse model. BC
94  2014 Use of vanilloids in urologic disorders. IC/PBS, NGB, OAB
95  2013 Anatomical and functional characterization of a duodeno-pancreatic neural reflex that can induce acute pancreatitis. CHEM, DRG, TRPA1
96  2013 Antidiuretic effect of antimuscarinic agents in rat model depends on C-fibre afferent nerves in the bladder. ADH, ALD, ANP, BNP
97  2013 Astrocytic TRPV1 ion channels detect blood-borne signals in the sensory circumventricular organs of adult mouse brains. AP, CVOs, MnPO, OVLT, SFO, Sol, TRPV1
98  2013 Effect of herpes simplex virus vector-mediated interleukin-4 gene therapy on bladder overactivity and nociception. HSV, IL-4
99  2013 Effects of herpes simplex virus vector-mediated enkephalin gene therapy on bladder overactivity and nociception. hPPE, HSV, IL
100  2013 Electroacupuncture improves thermal and mechanical sensitivities in a rat model of postherpetic neuralgia. CTB, EA, PHN