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Abbreviation : RXR
Long Form : retinoid X receptor
No. Year Title Co-occurring Abbreviation
2020 A Small Molecule, UAB126, Reverses Diet-Induced Obesity and its Associated Metabolic Disorders. ---
2020 Agonist binding directs dynamic competition among nuclear receptors for heterodimerization with retinoid X receptor. NRs, PPARgamma, RARalpha, VDR
2020 All-trans retinoic acid reduces the transcriptional regulation of intestinal sodium-dependent phosphate co-transporter gene (Npt2b). ATRA, C/EBP, Pi, RAR, VAD
2020 Bexarotene promotes microglia/macrophages - Specific brain - Derived Neurotrophic factor expression and axon sprouting after traumatic brain injury. BDA, BDNF, CCI, GAP43, MBP, PPARgamma, TBI
2020 Brain Cleanup as a Potential Target for Poststroke Recovery: The Role of RXR (Retinoic X Receptor) in Phagocytes. ---
2020 Classical pathways of gene regulation by retinoids. RA, RAR, RARE
2020 Combination of peroxisome proliferator-activated receptor gamma and retinoid X receptor agonists induces sodium/iodide symporter expression and inhibits cell growth of human thyroid cancer cells. PPARgamma, RFS
2020 Combinations of LXR and RXR agonists induce triglyceride accumulation in human HepaRG cells in a synergistic manner. LXR, NR
2020 Discovery and SAR of Natural-Product-Inspired RXR Agonists with Heterodimer Selectivity to PPARdelta-RXR. PPAR
10  2020 Dissecting myogenin-mediated retinoid X receptor signaling in myogenic differentiation. ---
11  2020 Distinguishing mode of action of compounds inducing craniofacial malformations in zebrafish embryos to support dose-response modeling in combined exposures. AhR, HDAC, MOA, PPARalpha, RA, RAR
12  2020 Dystrobrevin alpha gene is a direct target of the vitamin D receptor in muscle. DAPC, DTNA, VD3, VDR, VDRE
13  2020 Expression of retinoid receptors in hand eczema. OHSI, qRT-PCR, RAR
14  2020 Favorable outcomes in folliculotropic mycosis fungoides after multimodality treatment in a single-institution. FMF, MF, OS, RAR
15  2020 Functional characterization of retinoid X receptor with an emphasis on the mediation of organotin poisoning in the Pacific oyster (Crassostrea gigas). CgRXR, TBT, TPT
16  2020 Identification and Integrated Analysis of MicroRNA and mRNA Expression Profiles During Agonistic Behavior in Chinese Mitten Crab (Eriocheir sinensis) Using a Deep Sequencing Approach. DEGs, DEMs, KEGG, miRNAs, mRNAs, RAS, TG
17  2020 l-Thyroxin and the Nonclassical Thyroid Hormone TETRAC Are Potent Activators of PPARgamma. PPARgamma, THs
18  2020 Mass spectrometry-based iTRAQ analysis of serum markers in patients with pancreatic cancer. APAF-1, GO, IPA, PC, TGF-beta1
19  2020 Molecular determinants of MED1 interaction with the DNA bound VDR-RXR heterodimer. VDR
20  2020 Nuclear Receptors as Potential Therapeutic Targets for Myeloid Leukemia. APL, ATRA, NR, PPAR, RAR, VDR
21  2020 Of Retinoids and Organotins: The Evolution of the Retinoid X Receptor in Metazoa. 9-cis RA, NRs, TBT
22  2020 Ordered structure-forming properties of the intrinsically disordered AB region of hRXRgamma and its ability to promote liquid-liquid phase separation. AB_hRXG, IDPs, LLPS, NR, PMG-like
23  2020 PPAR-gamma, RXR, VDR, and COX-2 Expressions in gingival tissue samples of healthy individuals, periodontitis and peri-implantitis patients. COX, GI, PI, PPAR, PPD, VDR
24  2020 Retinoid X receptor agonists attenuates cardiomyopathy in streptozotocin-induced type 1 diabetes through LKB1-dependent anti-fibrosis effects. 9-cis-RA, Bex, BW, CFs, DCM, HG, LKB1, p70S6K, SD, siRNA, STZ, TGF-beta
25  2020 Retinoid X receptor modulates olfactory attraction through Galpha signaling in the migratory locusts. DETs, DopR1, GPCR, OctalphaR1, RA, raldh1, RNAi
26  2020 Simultaneous Mapping of Molecular Proximity and Comobility Reveals Agonist-Enhanced Dimerization and DNA Binding of Nuclear Receptors. FRET, RAR, SPIM
27  2020 The Echinodermata PPAR: Functional characterization and exploitation by the model lipid homeostasis regulator tributyltin. ACSL, LBD, PPAR, TBT
28  2020 The exploration of new therapeutic targets for HPV-negative head and neck squamous cell cancer through the construction of a ceRNA network and immune microenvironment analysis. ceRNAs, HNSCC, HPV, lncRNAs, miRNAs, mRNAs, NRP, VEGF
29  2020 The Novel Role of PPAR Alpha in the Brain: Promising Target in Therapy of Alzheimer's Disease and Other Neurodegenerative Disorders. AD, APP, PGC-1alpha, PPAR-alpha, PPREs
30  2020 The protective effects of bexarotene against advanced glycation end-product (AGE)-induced degradation of articular extracellular matrix (ECM). AGE, ECM, MMPs, OA
31  2020 The retinoid X receptor: a nuclear receptor that modulates the sleep-wake cycle in rats. ---
32  2020 The rhythm of hormones in genes. GR, GRE, HSP
34  2020 Triterpenes from Poria cocos are revealed as potential retinoid X receptor selective agonists based on cell and in silico evidence. APL, HTA, PA, PPAC
35  2020 Unraveling the Hierarchy of cis and trans Factors That Determine the DNA Binding by Peroxisome Proliferator-Activated Receptor gamma. ChIP-seq, DR1, LDTFs, PPARgamma
36  2019 3H-Imidazo[4,5-b]pyridine-6-carboxylic acid derivatives as rexinoids with reduced teratogenicity. 8, CATF-PMN
37  2019 A partial agonist for retinoid X receptor mitigates experimental colitis. BMDMs, DHA, IBD, Nur77, PPARdelta
38  2019 A review of the molecular design and biological activities of RXR agonists. NRs
39  2019 A revisited version of the apo structure of the ligand-binding domain of the human nuclear receptor retinoic X receptor alpha. LBD, NRs
40  2019 Activation of retinoid X receptor by bexarotene attenuates neuroinflammation via PPARgamma/SIRT6/FoxO3a pathway after subarachnoid hemorrhage in rats. p-FoxO3a, SAH, SIRT6
41  2019 Activation of RXR by bexarotene inhibits inflammatory conditions in human rheumatoid arthritis fibroblast‑like synoviocytes. FLS, IL, MMP, RA
42  2019 Adapalene suppressed the proliferation of melanoma cells by S-phase arrest and subsequent apoptosis via induction of DNA damage. ATRA, RAR
43  2019 All-trans retinoic acid suppresses bone morphogenetic protein 4 in mouse diabetic nephropathy through a unique retinoic acid response element. ATRA, BMP4, DN, RARalpha, RAREs
44  2019 Alternative retinoid X receptor (RXR) ligands. NRs, RXRs
45  2019 Anti-inflammatory effects of naturally occurring retinoid X receptor agonists isolated from Sophora tonkinensis Gagnep. via retinoid X receptor/liver X receptor heterodimers. AD, ATF3, IL, LXR, mRNA, NF-kappaB
46  2019 Assessing Autophagy During Retinoid Treatment of Breast Cancer Cells. APL, ATRA, RAR
47  2019 Assessing the endocrine disrupting potentials and genotoxicity in environmental samples from Taiwanese rivers. PAHs
48  2019 Carbamazepine disrupts molting hormone signaling and inhibits molting and growth of Eriocheir sinensis at environmentally relevant concentrations. 20-HE, CBZ, CHH, EcR, MI, MIH, TBM
49  2019 Causal associations of autoimmune thyroiditis and papillary thyroid carcinoma: mRNA expression of selected nuclear receptors and other molecular targets. AIT, PR, PTC, TR
50  2019 Comprehensive study of nuclear receptor DNA binding provides a revised framework for understanding receptor specificity. NRs, PBMs
51  2019 Dual conformation of the ligand induces the partial agonistic activity of retinoid X receptor alpha (RXRalpha). CBt-PMN, hRXRalpha, RXRalpha
52  2019 Dynamic enhancers control skeletal muscle identity and reprogramming. ERR, JUN, MEF, Pgc1a, SIX
53  2019 Effects of 9-cis-retinoic acid on the proliferation and apoptosis of cutaneous T-cell lymphoma cells. 9-cis-RA, CTCL, RAR
54  2019 Exposure to the RXR Agonist SR11237 in Early Life Causes Disturbed Skeletal Morphogenesis in a Rat Model. EO, micro-CT
55  2019 Expression and role of peroxisome proliferator-activated receptors in the porcine early placenta trophoblast. PG, PPARs
56  2019 Farnesoid X receptor represses matrix metalloproteinase 7 expression, revealing this regulatory axis as a promising therapeutic target in colon cancer. FXR, MMP7
57  2019 Fluorine-18 (18F)-labeled retinoid x receptor (RXR) partial agonist whose tissue transferability is affected by other RXR ligands. CTCL, PET
58  2019 Gene regulation analysis of the effects of evodiamine on tongue squamous cell carcinoma. EVO, IL, TSCC
59  2019 Hemodynamics-Based Strategy of Using Retinoic Acid Receptor and Retinoid X Receptor Agonists to Induce MicroRNA-10a and Inhibit Atherosclerotic Lesion. AMR-10a, ECs, miR, OS, PreR-10a, PS, RAR, RARE
60  2019 Identification of Macrophage Genotype and Key Biological Pathways in Circulating Angiogenic Cell Transcriptome. CAC, CAC, FXR, LXR, TAM
61  2019 Interplay of Protein Disorder in Retinoic Acid Receptor Heterodimer and Its Corepressor Regulates Gene Expression. RAR
62  2019 Limited Chemical Structural Diversity Found to Modulate Thyroid Hormone Receptor in the Tox21 Chemical Library. TRs
63  2019 Marginal Vitamin A Deficiency Affects the Expression Levels and Localization of Retinoic Acid Receptor and Retinoid X Receptor in Rats Meibomian Gland. MVAD, P4w, RAR, VAN
64  2019 Measurement of the agonistic activities of monohydroxylated polychlorinated biphenyls at the retinoid X and retinoic acid receptors using recombinant yeast cells. PCBs, RAR
65  2019 Methods to Assess Activity and Potency of Rexinoids Using Rapid Luciferase-Based Assays: A Case Study with NEt-TMN. Bex, RAR, RxRE
66  2019 Methods to Generate an Array of Novel Rexinoids by SAR on a Potent Retinoid X Receptor Agonist: A Case Study with NEt-TMN. Bex, FDA, RAR, SAR
67  2019 Molecular Mechanism of Cancer Susceptibility Associated with Fok1 Single Nucleotide Polymorphism of VDR in Relation to Breast Cancer SNPs, VDR
68  2019 Multispecies study: low-dose tributyltin impairs ovarian theca cell cholesterol homeostasis through the RXR pathway in five mammalian species including humans. TBT
69  2019 Neuroprotective effect of naturally occurring RXR agonists isolated from Sophora tonkinensis Gagnep. on amyloid-beta-induced cytotoxicity in PC12 cells. ABCA1, AD, LXR
70  2019 Novel insights into the combined effect of triorganotin compounds and all-trans retinoic acid on expression of selected proteins associated with tumor progression in breast cancer cell line MDA-MB-231: Proteomic approach. ATRA, RAR
71  2019 Porcine interleukin-6 enhances the expression of CYP2C33 through a constitutive androstane receptor/retinoid X receptor-mediated pathway. CAR, IL
72  2019 Regulation of RXR-RAR Heterodimers by RXR- and RAR-Specific Ligands and Their Combinations. RAR
73  2019 Retinoid receptor-based signaling plays a role in voltage-dependent inhibition of invertebrate voltage-gated Ca2+ channels. RAR, VGCCs
74  2019 Retinoid X receptor-mediated neuroprotection via CYP19 upregulation and subsequent increases in estradiol synthesis. OGD
75  2019 Role of RXRbeta in platelet function and arterial thrombosis. 9cRA, MA, MK, WT
76  2019 Self-Assembly Of Retinoid Nanoparticles For Melanoma Therapy. ATRA, HDAC, RAR, RHA, TEM
77  2019 Sex-regulated gene dosage effect of PPARalpha on synaptic plasticity. AMPA, PPARalpha
78  2019 Steroids from the Deep-Sea-Derived Fungus Penicillium granulatum MCCC 3A00475 Induced Apoptosis via Retinoid X Receptor (RXR)-alpha Pathway. PARP
79  2019 Testing Novel Pyrimidinyl Rexinoids: A New Paradigm for Evaluating Rexinoids for Cancer Prevention. Bex, LG268, py, SREBP
80  2019 Therapeutic modulation of retinoid X receptors - SAR and therapeutic potential of RXR ligands and recent patents. ---
81  2019 Tributyltin Affects Retinoid X Receptor-Mediated Lipid Metabolism in the Marine Rotifer Brachionus koreanus. LC10, PUFAs, SFAs, TBT
82  2019 Vitamin D and testosterone co-ordinately modulate intracellular zinc levels and energy metabolism in prostate cancer cells. 9-cis RA, AR, PCa, PPARalpha, TPP, VDR
83  2019 [Role of pregnane X receptor (PXR) in endobiotic metabolism]. PXR
84  2019 [The regulation of retinoid X receptor-mediated oxidative stress pathway in rat pulmonary ischemia/reperfusion injury]. I/R, Nrf2, PIRI, SD
85  2018 All-Trans Retinoic Acid Enhances Matrix Metalloproteinase 2 Expression and Secretion in Human Myeloid Leukemia THP-1 Cells. ATRA, MMP-2, RAR, RAS
86  2018 Bexarotene - a novel modulator of AURKA and the primary cilium in VHL-deficient cells. AURKA, HTS, RCC, VHL
87  2018 Bexarotene, a Selective RXRalpha Agonist, Reverses Hypotension Associated with Inflammation and Tissue Injury in a Rat Model of Septic Shock. HR, iNOS, LDH, LPS, MAP, MPO, PPARs
88  2018 Bisphenol A (BPA) modulates the expression of endocrine and stress response genes in the freshwater snail Physa acuta. BPA, EDC, ER, ERR, GST
89  2018 Computer-Assisted Discovery of Retinoid X Receptor Modulating Natural Products and Isofunctional Mimetics. NPs
90  2018 Conservation of DNA and ligand binding properties of retinoid X receptor from the placozoan Trichoplax adhaerens to human. PBMs
91  2018 Design, Synthesis, and Characterization of Globular Orphan Nuclear Receptor Regulator with Biological Activity in Soft Tissue Sarcoma. ---
92  2018 Dietary vitamin D3 supplementation protects laying hens against lipopolysaccharide-induced immunological stress. FSH, iNOS, LH, LPS, NF-kappaB, pIgR, VD3
93  2018 Disruption of Nuclear Receptor Signaling Alters Triphenyl Phosphate-Induced Cardiotoxicity in Zebrafish Embryos. hpf, TPHP
94  2018 Effects of Organotins on Crustaceans: Update and Perspectives. CHH, OTs, TBT
95  2018 Examination of VDR/RXR/DRIP205 Interaction, Intranuclear Localization, and DNA Binding in Ras-Transformed Keratinocytes and Its Implication for Designing Optimal Vitamin D Therapy in Cancer. hRXRalpha, MAPK, VDR
96  2018 Extensive and functional overlap of the STAT6 and RXR cistromes in the active enhancer repertoire of human CD14+ monocyte derived differentiating macrophages. IFN, IL
97  2018 Fucosterol Causes Small Changes in Lipid Storage and Brassicasterol Affects some Markers of Lipid Metabolism in Atlantic Salmon Hepatocytes. ---
98  2018 Heme oxygenase-1 protects airway epithelium against apoptosis by targeting the proinflammatory NLRP3-RXR axis in asthma. HO-1, IL, NLRP3, pAECs
99  2018 HX600, a synthetic agonist for RXR-Nurr1 heterodimer complex, prevents ischemia-induced neuronal damage. lysoPCs, NR4A
100  2018 Identification of influential proteins in the classical retinoic acid signaling pathway. GSA, RA, RAR