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Abbreviation : RXRs
Long Form : retinoid X receptors
No. Year Title Co-occurring Abbreviation
2022 Modulation of Rxrα Expression in Mononuclear Phagocytes Impacts on Cardiac Remodeling after Ischemia-Reperfusion Injury. MI
2022 Retinoid X Receptor: Cellular and Biochemical Roles of Nuclear Receptor with a Focus on Neuropathological Involvement. ---
2022 Retinoid-X receptor agonists increase thyroid hormone competence in lower jaw remodeling of pre-metamorphic Xenopus laevis tadpoles. NRs, TH, TRs
2022 Rexinoids Modulate Effector T Cell Expression of Mucosal Homing Markers CCR9 and α4β7 Integrin and Direct Their Migration In Vitro. ATRA, RARs
2022 The rexinoid V-125 reduces tumor growth in preclinical models of breast and lung cancer. ---
2022 The Sin3A/MAD1 Complex, through Its PAH2 Domain, Acts as a Second Repressor of Retinoic Acid Receptor Beta Expression in Breast Cancer Cells. RARs, SMI
2021 GYY4137 Regulates Extracellular Matrix Turnover in the Diabetic Kidney by Modulating Retinoid X Receptor Signaling. DN, ECM, MCs, PAI-1, PPARgamma, RARs
2021 Molting process revealed by the detailed expression profiles of RXR1/RXR2 and mining the associated genes in a spider mite, Panonychus citri. EcR
2021 Overview of all-trans-retinoic acid (ATRA) and its analogues: Structures, activities, and mechanisms in acute promyelocytic leukaemia. APL, ATRA, RARs
10  2021 Retinoids Decrease Soluble MICA Concentration by Inhibiting the Enzymatic Activity of ADAM9 and ADAM10. HCC, MICA, NK, RARs, sMICA
11  2021 Role of Retinoid X Receptors (RXRs) and dietary vitamin A in Alzheimer's disease: Evidence from clinicopathological and preclinical studies. AD, MCI, RA, RARbeta, ROS, RXRgamma, VitA
12  2021 Structural Insights into the Interaction of the Intrinsically Disordered Co-activator TIF2 with Retinoic Acid Receptor Heterodimer (RXR/RAR). LBD, NR, RARs
13  2021 The Interactions of Insulin and Vitamin A Signaling Systems for the Regulation of Hepatic Glucose and Lipid Metabolism. RA, RARs, VA
14  2021 The multi-faceted role of retinoid X receptor in cardiovascular diseases. FAs, NRs
15  2021 The role of the retinoid receptor, RAR/RXR heterodimer, in liver physiology. RARs
16  2021 The RXR Agonist MSU42011 Is Effective for the Treatment of Preclinical HER2+ Breast Cancer and Kras-Driven Lung Cancer. ---
17  2021 Thyroid hormone and thyroid hormone nuclear receptors: History and present state of art. TRs
18  2021 Vitamin A5/X controls stress-adaptation and prevents depressive-like behaviors in a mouse model of chronic stress. 9CDHRA
19  2020 Computational determination of human PPARG gene: SNPs and prediction of their effect on protein functions of diabetic patients. PPARG
20  2020 Design of synthetic retinoids. RARs
21  2020 Discovery of a "Gatekeeper" Antagonist that Blocks Entry Pathway to Retinoid X Receptors (RXRs) without Allosteric Ligand Inhibition in Permissive RXR Heterodimers. LBD, LBP, RXR
22  2020 DNA recognition by retinoic acid nuclear receptors. DBDs, ESI-MS, ITC, RARs
23  2020 Fluorescence properties of retinoid X receptor antagonist NEt-SB. ---
24  2020 In utero exposure to phenanthrene induces hepatic steatosis in F1 adult female mice. PAHs, PHE
25  2020 Long-term exposure to phenanthrene at environmental-level induces intestinal dysbiosis and disrupted hepatic lipid metabolism in mice. FMT, LXRbeta, PAHs, PHE, PPARs
26  2020 Natural and synthetic retinoid X receptor ligands and their role in selected nuclear receptor action. CAR, FXR, LXRs, PPARs, PXR, TRs
27  2020 Natural ligands of RXR receptors. HTS, NR
28  2020 Nuclear receptors: Lipid and hormone sensors with essential roles in the control of cancer development. AR, ER, GR, LXRs, NRs, PPARs, RARs, TR
29  2020 Repurposing a novel anti-cancer RXR agonist to attenuate murine acute GVHD and maintain graft-versus-leukemia responses. GVHD, NR
30  2020 Structural basis for DNA recognition and allosteric control of the retinoic acid receptors RAR-RXR. RAREs, RARs
31  2020 VHL enhances 9-cis-retinoic acid treatment by down-regulating retinoid X receptor alpha in renal cell carcinomas. RCC, VHL
32  2019 A Novel Biphenyl-based Chemotype of Retinoid X Receptor Ligands Enables Subtype and Heterodimer Preferences. ---
33  2019 A retinoid X receptor partial agonist attenuates pulmonary emphysema and airway inflammation. BAL, CSE, CXCL5, IFN, KC, MMP-9, NR, PPE, TIMP-1, VEGF
34  2019 Alternative retinoid X receptor (RXR) ligands. NRs, RXR
35  2019 Competitive Binding Assay with an Umbelliferone-Based Fluorescent Rexinoid for Retinoid X Receptor Ligand Screening. ---
36  2019 Computer-Assisted Discovery and Structural Optimization of a Novel Retinoid X Receptor Agonist Chemotype. ---
37  2019 Genomic and non-genomic pathways are both crucial for peak induction of neurite outgrowth by retinoids. RA, RARs
38  2019 Ligand Design for Modulation of RXR Functions. ant, HTS, NR
39  2019 Molecular docking, dynamics, and pharmacology studies on bexarotene as an agonist of ligand-activated transcription factors, retinoid X receptors. ---
40  2019 Recent insights on the role and regulation of retinoic acid signaling during epicardial development. RAR
41  2019 Regulation of cellular senescence by retinoid X receptors and their partners. SASP
42  2019 Retinoid X receptor agonist LG100268 modulates the immune microenvironment in preclinical breast cancer models. LG268
43  2019 Retinoid x receptor modulation protects against ER stress response and rescues glaucoma phenotypes in adult mice. sRXRms
44  2019 Tuning Nuclear Receptor Selectivity of Wy14,643 towards Selective Retinoid X Receptor Modulation. PPARs
45  2018 A novel gene expression analytics-based approach to structure aided design of rexinoids for development as next-generation cancer therapeutics. CTCL
46  2018 Bexarotene cannot reduce amyloid beta plaques through inhibition of production of amyloid beta peptides: in silico and in vitro study. APOE4, PPARgamma
47  2018 Bexarotene Modulates Retinoid-X-Receptor Expression and Is Protective Against Neurotoxic Endoplasmic Reticulum Stress Response and Apoptotic Pathway Activation. ---
48  2018 DHA upregulates FADS2 expression in primary cortical astrocytes exposed to vitamin A. ALA, DHA, PA, PPARs, VA
49  2018 Effects of thyroid hormone disruption on the ontogenetic expression of thyroid hormone signaling genes in developing zebrafish (Danio rerio). DIOs, NCOAs, NCORs, PTU, THs
50  2018 In silico molecular interaction of bisphenol analogues with human nuclear receptors reveals their stronger affinity vs. classical bisphenol A. BPA, PPARs
51  2018 Modulation of RXR-DNA complex assembly by DNA context. DR1, NMR
52  2018 Prenatal Exposure to Benzophenone-3 Impairs Autophagy, Disrupts RXRs/PPARgamma Signaling, and Alters Epigenetic and Post-Translational Statuses in Brain Neurons. BP-3, PPARgamma
53  2018 Retinoic acid receptor agonist as monotherapy for early-stage mycosis fungoides: does it work? CR, MF, OR, RARs
54  2018 RXR Ligands Modulate Thyroid Hormone Signaling Competence in Young Xenopus laevis Tadpoles. Bex, TBT, TH, TREs, TRs
55  2018 Scaffold hopping from synthetic RXR modulators by virtual screening and de novo design. ---
56  2017 A multi-tiered, in vivo, quantitative assay suite for environmental disruptors of thyroid hormone signaling. BDE-47, NF, pf, TBBPA, TH, TRs
57  2017 Disturbed Vitamin A Metabolism in Non-Alcoholic Fatty Liver Disease (NAFLD). HSCs, NAFLD, NASH, PNPLA3I148M, RARs, RBP4
58  2017 Effect of a retinoid X receptor partial agonist on airway inflammation and hyperresponsiveness in a murine model of asthma. AHR, BAL, LXRs, NR, OVA, PAS, PPARs, RARs, VDRs
59  2017 Ligand Dependent Switch from RXR Homo- to RXR-NURR1 Heterodimerization. AF-2, NURR1
60  2017 Liver X receptor agonist treatment significantly affects phenotype and transcriptome of APOE3 and APOE4 Abca1 haplo-deficient mice. ABCA1, APOE, LXRs
61  2017 Retinoids Regulate Adipogenesis Involving the TGFbeta/SMAD and Wnt/beta-Catenin Pathways in Human Bone Marrow Mesenchymal Stem Cells. hBMSCs, PPARgamma, RARs, shRNA, TGF-beta
62  2017 RXR heterodimers orchestrate transcriptional control of neurogenesis and cell fate specification. LXR, NR, RAR
63  2017 The multi-faceted role of retinoid X receptor in bone remodeling. NR
64  2016 An Endogenous Mammalian Retinoid X Receptor Ligand, At Last! ---
65  2016 Decreased Expression of Retinoid X Receptors During Human and Azoxymethane-induced Colorectal Carcinogenesis in the Rat. AOM
66  2016 Effect of LXR/RXR agonism on brain and CSF Abeta40 levels in rats. AD, APOE, CSF, LXRs
67  2016 EPA/DHA and Vitamin A Supplementation Improves Spatial Memory and Alleviates the Age-related Decrease in Hippocampal RXRgamma and Kinase Expression in Rats. DHA, EPA, RARs
68  2016 Natural and Structure-based RXR Ligand Scaffolds and Their Functions. NR
69  2016 Preclinical PET Neuroimaging of [11C]Bexarotene. PET
70  2016 Recent Progress in the Design and Discovery of RXR Modulators Targeting Alternate Binding Sites of the Receptor. ---
71  2016 Retinoid X Receptor Ligands with Anti-Type 2 Diabetic Activity. PPARgamma
72  2016 Retinoids and rexinoids in cancer prevention: from laboratory to clinic. RARs
73  2016 Solution Behavior of the Intrinsically Disordered N-Terminal Domain of Retinoid X Receptor alpha in the Context of the Full-Length Protein. NTD
74  2016 The combined effects of all-trans-retinoic acid and docosahexaenoic acid on the induction of apoptosis in human breast cancer MCF-7 cells. ATRA, DHA, RARs
75  2016 Treatment with retinoid X receptor agonist IRX4204 ameliorates experimental autoimmune encephalomyelitis. EAE, iTreg, Th
76  2015 9-cis-13,14-Dihydroretinoic Acid Is an Endogenous Retinoid Acting as RXR Ligand in Mice. 9CDHRA
77  2015 Bexarotene-Activated Retinoid X Receptors Regulate Neuronal Differentiation and Dendritic Complexity. APOE, ES
78  2015 Cloning, mRNA expression and transcriptional regulation of five retinoid X receptor subtypes in yellow catfish Pelteobagrus fulvidraco by insulin. Pf-rxr
79  2015 Danqi Pill regulates lipid metabolism disorder induced by myocardial ischemia through FATP-CPTI pathway. apoB, CPT I, DQP, EF, FATP, HMGCR, LDL, MI, PPARalpha, TG
80  2015 Docking simulations suggest that all-trans retinoic acid could bind to retinoid X receptors. 9cRA, ATRA, RARs
81  2015 Elevated Farnesoid XReceptor (FXR) and Retinoid XReceptors (RXRs) expression is associated with less tumor aggressiveness and favourable prognosis in patients with pancreatic adenocarcinoma. FXR
82  2015 Identification of Bexarotene as a PPARgamma Antagonist with HDX. CTCL, HDX, NRs, PPARgamma
83  2015 Inhibition of lipopolysaccharide-induced gene expression by liver X receptor ligands in macrophages involves interference with early growth response factor 1. COX-2, LXRs, mPGES-1
84  2015 Involvement of Different networks in mammary gland involution after the pregnancy/lactation cycle: Implications in breast cancer. NF-kappaB, RARs, TGF-beta
85  2015 Modulating Intrafollicular Hormonal Milieu in Controlled Ovarian Stimulation: Insights From PPAR Expression in Human Granulosa Cells. COS, GCs, PPARs
86  2015 Molecular cloning and expression analysis of the retinoid X receptor (RXR) gene in golden pompano Trachinotus ovatus fed Artemia nauplii with different enrichments. dph, RXR
87  2015 Molecular Signaling Mechanisms of Natural and Synthetic Retinoids for Inhibition of Pathogenesis in Alzheimer's Disease. AD, RARs
88  2015 Pituitary specific retinoid-X receptor ligand interactions with thyroid hormone receptor signaling revealed by high throughput reporter and endogenous gene responses. Luc, TH, TR
89  2015 Protein Kinase C Is Involved in the Induction of ATP-Binding Cassette Transporter A1 Expression by Liver X Receptor/Retinoid X Receptor Agonist in Human Macrophages. 9cRA, ABCA1, AP-1, JNK, LXRs, PI3K, PKC
90  2015 Protein Kinase C Is Involved in the Induction of ATP-Binding Cassette Transporter A1 Expression by Liver X Receptor/Retinoid X Receptor Agonist in Human Macrophages. 9cRA, ABCA1, AP-1, JNK, LXRs, PI3K, PKC
91  2015 Retinoid X receptors orchestrate osteoclast differentiation and postnatal bone remodeling. LXR, MAFB, SREBP-1c
92  2015 Selective ligand activity at Nur/retinoid X receptor complexes revealed by dimer-specific bioluminescence resonance energy transfer-based sensors. BRET, CoA, Luc, NRs, PCA, YFP
93  2015 Structural basis of natural promoter recognition by the retinoid X nuclear receptor. DBD, DR1
94  2015 The Continuing Failure of Bexarotene in Alzheimer's Disease Mice. AD, APOE, BEXA
95  2015 Transcriptional Factors Mediating Retinoic Acid Signals in the Control of Energy Metabolism. RA, RARs, VA
96  2015 TSLP expression in the skin is mediated via RARgamma-RXR pathways. AD, ATRA, RARs, VDR
97  2014 A RXR ligand 6-OH-11-O-hydroxyphenanthrene with antitumour properties enhances (-)-epigallocatechin-3-gallate activity in three human breast carcinoma cell lines. EGCG, FOXO3a
98  2014 Architecture of DNA Bound RAR heterodimers. RA, RARs
99  2014 Development of yeast reporter assay for screening specific ligands of retinoic acid and retinoid X receptor subtypes. RARs
100  2014 Diarylamines incorporating hexahydrophenalene or octahydrobenzoheptalene as retinoid X receptor (RXR)-specific agonists. RARs, RXR