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Abbreviation : SD
Long Form : Sprague-Dawley rats
No. Year Title Co-occurring Abbreviation
2019 Plant-Derived Oleanolic Acid (OA) Ameliorates Risk Factors of Cardiovascular Diseases in a Diet-Induced Pre-Diabetic Rat Model: Effects on Selected Cardiovascular Risk Factors. CRP, IL-6, MAP, Met, NC, OA, OA, PC, TGs, TNF-alpha
2019 [Effects of endurance exercise on synaptic plasticity in cerebral cortex of aged rats and related regulatory mechanism]. AMPKalpha1, BDNF, CaMK IIalpha, HE, mTOR, SOD, SPF, SYN1
2018 Colonic indole, gut bacteria metabolite of tryptophan, increases portal blood pressure in rats. ABP, PBF, PBP, PH, SD-PH
2018 Combined Antihypertensive Effect of Paeoniflorin Enriched Extract and Metoprolol in Spontaneously Hypertensive Rats. BP, eNOS, MP, RE, SHR
2018 Urinary Level of Liver-Type Fatty Acid Binding Protein Reflects the Degree of Tubulointerstitial Damage in Polycystic Kidney Disease. L-FABP, PKD
2018 [Efficacy of compound Dendrobium on PI3K/AKT/eNOS signaling pathway in hypertensive rats induced by "dietary disorders"]. AI, eNOS, ET-1, HDL, HE, ICAM-1, LDL-C, NO, TG
2016 Genetic predisposition and early life experience interact to determine glutamate transporter (GLT1) and solute carrier family 12 member 5 (KCC2) levels in rat hippocampus. ADHD, SHR, WKY
2016 Liguzinediol protects against cardiac fibrosis in rats in vivo and in vitro. DOX, HE, MMPs, TIMPs
2016 Long-term trihexyphenidyl exposure alters neuroimmune response and inflammation in aging rat: relevance to age and Alzheimer's disease. AC, AD, MHC, MWM, NS, PD, qRT-PCR, THP
10  2014 Nicotine-stimulated release of [3H]norepinephrine is reduced in the hippocampus of an animal model of attention-deficit/hyperactivity disorder, the spontaneously hypertensive rat. ADHD, SHR, WKY
11  2014 Relaxin does not improve Angiotensin II-induced target-organ damage. Ang, dTGR
12  2013 Comparing effects of carbohydrate (CHO) blockers and trivalent chromium on CHO-induced insulin resistance and elevated blood pressure in rats. BP, CBs, CHO, CHO, Cr, IR, SBP
13  2013 Evidence for reduced tonic levels of GABA in the hippocampus of an animal model of ADHD, the spontaneously hypertensive rat. ADHD, GABA, SHR, WKY
14  2013 Lower doses of isoflurane treatment has no beneficial effects in a rat model of intracerebral hemorrhage. ICH
15  2012 Evidence that renal arginine transport is impaired in spontaneously hypertensive rats. NO, SHR
16  2012 Fraction SX of maitake mushroom favorably influences blood glucose levels and blood pressure in streptozotocin-induced diabetic rats. ACE, BP, BW, i.p, LNAME, NO, SBP, STZ
17  2011 High dose astaxanthin lowers blood pressure and increases insulin sensitivity in rats: are these effects interdependent? Asta, BP, NO, RAS
18  2011 Subdose of fasudil suppresses myocardial fibrosis in aldosterone-salt-treated uninephrectomized rats. ANP, BNP, MYPT1, TGF-beta1
19  2010 Anxiety-related behaviour of low brain angiotensinogen transgenic rats in the canopy test. SAP, TGR
20  2010 Immunosuppression with an interleukin-2 fusion protein leads to improved LV function in experimental ischemic cardiomyopathy. CHF, IL-2, LAD, LV, LVP, MI
21  2010 Influence of gel and powdered formulations of coenzyme Q10 on metabolic parameters in rats. CoQ10, SBP
22  2010 Maitake mushroom extracts ameliorate progressive hypertension and other chronic metabolic perturbations in aging female rats. RAS, SBP
23  2010 Nuclear orphan receptor Nor-1 contributes to depressive behavior in the Wistar-Kyoto rat model of depression. DMI, FST, GR, Nor-1, PEI, shRNA, WKY
24  2010 Preserved memory capacities in aged Lou/C/Jall rats. NMDAR
25  2010 Which is the most suitable and effective route of administration for mesenchymal stem cell-based immunomodulation therapy in experimental kidney transplantation: endovenous or arterial? ACR, EGFP, MSC
26  2009 Decrease in the kainate-induced wet dog shake behavior in genetically epilepsy-prone rats: possible involvement of an impaired synaptic transmission to the 5-HT(2A) receptor. WDS
27  2009 Endogenous cardiotonic steroids and differential patterns of sodium pump inhibition in NaCl-loaded salt-sensitive and normotensive rats. ANP, cGMP, DS, MBG, SBP
28  2009 Variability in the occurrence of nitric oxide synthase immunoreactivity in different populations of rat sympathetic preganglionic neurons. AM, CAA, ChAT, IML, NOS, SHR, SPN, WKY
29  2008 Blood pressure lowering effects of niacin-bound chromium(III) (NBC) in sucrose-fed rats: renin-angiotensin system. ACE, NBC, RAS, SBP
30  2008 Clinical and pathological findings in experimental brucellosis in pregnant rats. CFU
31  2008 SB 234551 selective ET(A) receptor antagonism: perfusion/diffusion MRI used to define treatable stroke model, time to treatment and mechanism of protection. DWI, Gd, MCAO, PWI, ROI, SHR
32  2007 Development of hyperfibrinogenemia in spontaneously hypertensive and hyperlipidemic rats: a potentially useful animal model as a complication of hypertension and hyperlipidemia. HLR, SHHR, SHR, WKY
33  2007 Effects of pioglitazone on increases in visceral fat accumulation and oxidative stress in spontaneously hypertensive hyperlipidemic rats fed a high-fat diet and sucrose solution. CAT, Cu,Zn-SOD, GPx, HFDS, LPO, NEFA, SHHR
34  2007 [Effects of omapatrilat on endothelin-1-induced proliferation and synthesis of cardiac fibroblasts]. CFs, FCM, NO, OMA
35  2006 Altered expression of BK channel beta1 subunit in vascular tissues from spontaneously hypertensive rats. BP, SHR, WKY
36  2006 Dynamic expression of the angiotensin II type 2 receptor and duodenal mucosal alkaline secretion in the Sprague-Dawley rat. AT2R, DMAS
37  2005 Effects of genistein on the expression of hepatic genes in two rat strains (Sprague-Dawley and Wistar). apoA-I, EE, GEN, IGFBP-1
38  2005 Enhancement of the coagulation system in spontaneously hypertensive and hyperlipidemic rats. ATIII, SHHR
39  2005 Impaired cardiac and sympathetic autonomic control in rats differing in acetylcholine receptor sensitivity. AChR, BRS, HRV
40  2005 The effect of non-insulin dependent diabetes mellitus on uncontrolled hemorrhage in a rodent model. CHV, DM, GL, HR, Lac, MAP, ZDF
41  2004 Observations on experimental marginal periodontitis in rats. ABC, CEJ
42  2004 Resistance to ischemic acute renal failure in the Brown Norway rat: a new model to study cytoprotection. ARF
43  2004 Sleep-related sympathovagal imbalance in SHR. HF, LF, RR, SHR, WKY
44  2004 The expression and activity of renal nitric oxide synthase and circulating nitric oxide in polycystic kidney disease rats. cNOS, iNOS, NO, PKD
45  2003 Entacapone protects from angiotensin II-induced inflammation and renal injury. Ang II, COMT, dTGR, ICAM-1, RT-PCR
46  2003 Extent and timeliness of tissue repair determines the dose-related hepatotoxicity of chloroform. BUN, GC, PBPK, SDH
47  2002 Angiotensin II subtype 1 (AT1) receptors contribute to ischemic contracture and regulate chemomechanical energy transduction in isolated transgenic rat (alphaMHC-hAT1)594-17 hearts. AT1, CF, IRB, LVDP
48  2002 Does hypertension alone lead to cognitive decline in spontaneously hypertensive rats? SHR, WKY, WM
49  2002 Increased carotid wall elastic modulus and fibronectin in aldosterone-salt-treated rats: effects of eplerenone. ALDO, EPL, MCSA
50  2002 Prevention of hypertension, hyperglycemia and vascular oxidative stress by aspirin treatment in chronically glucose-fed rats. GPx, SBP, SOD
51  2002 Regulation of cardiac bradykinin B1- and B2-receptor mRNA in experimental ischemic, diabetic, and pressure-overload-induced cardiomyopathy. AB, B1R, B2R, BKR, DM, LAD, LEVDP, LV, LVH, MI, RPA, STZ
52  2002 Suppression of dextran sulfate sodium-induced colitis in kininogen-deficient rats and non-peptide B2 receptor antagonist-treated rats. BN-Ka, BN-Ki, DSS, EC, UC
53  2002 Ventilatory phenotypes among four strains of adult rats. BN, FHH
54  2001 Cardiovascular actions of chicken-meat extract in normo- and hypertensive rats. SHR, WKY
55  2001 Hypercholesterolemia alters endotoxin-induced endothelial cell adhesion molecule expression. CAM, HC, mAb
56  2001 Increased intimal hyperplasia after carotid endarterectomy in spontaneously hypertensive rats. CEA, SHR
57  2000 Proximal tubule Na transporter responses are the same during acute and chronic hypertension. DPP-IV, NaPi2, NHE3, NKA, PT, SHR, YSD, YSHR
58  1999 Contractility and endothelium-dependent relaxation of resistance vessels in polycystic kidney disease rats. ACh, ADPKD, HSPRD, L-NAME, NA, PKD
59  1999 Endothelial dysfunction in the aorta of transgenic rats harboring the mouse Ren-2 gene. AII, ET-1, NE, NO
60  1999 Resetting of exaggerated tubuloglomerular feedback activity in acutely volume-expanded young SHR. SFP, SHR, TGF, VE, WKY
61  1998 Effects of quinapril, losartan and hydralazine on cardiac hypertrophy and beta-adrenergic neuroeffector mechanisms in transgenic (mREN2)27 rats. ACE, mREN2, NPY
62  1998 Redistribution of Na+/H+ exchanger isoform NHE3 in proximal tubules induced by acute and chronic hypertension. GH, NHE, SHR
63  1998 Transgenic hypertensive rats show a reduced angiotensin II induced [Ca2+]i response in glomerular mesangial cells. Ang II, MC, SHR, WKY
64  1997 Angiotensin II mediates cell hypertrophy in vascular smooth muscle cultures from hypertensive Ren-2 transgenic rats by an amiloride- and furosemide-sensitive mechanism. AII, TGR, VSMC
65  1997 Paramedian reticular nucleus may be unrelated to the development of hypertension in spontaneously hypertensive rats. PRN, SABP, SHR, WKY
66  1997 Urinary kallikrein in Dahl-Iwai salt-sensitive and -resistant rats. SR, SS
67  1996 High-salt diet upregulates kininogen and downregulates tissue kallikrein expression in Dahl-SS and SHR rats. Dahl SS, SHR
68  1996 Lack of contribution of circulatory kinin elevated by captopril to induce hypotension in normotensive and hypertensive rats. BK, HR, MBP
69  1995 Cell-free thymic extract from hypertensive rats induces hypertension in normotensive rats. SHR, WKYs
70  1995 Differential antiarrhythmic potency of adenosine in normotensive and spontaneously hypertensive rats. SHR, VF, WKY
71  1995 Does low frequency power of arterial blood pressure reflect sympathetic tone? ABP, SHR, SpNA, TGR, WKY
72  1995 Increased dietary NaCl intake influences lens transport properties in Sprague-Dawley rats. DR, DS, PDt
73  1995 Increasing development of pepsinogen-altered pyloric glands and adenocarcinoma in glandular stomach of analbuminemic rats. MNNG, NAR, PAPG
74  1995 [The variable number of tandem repeats in the renin gene of rats and possible significance in hypertension]. PCR, SHR, VNTR, WKY
75  1994 A new restriction fragment length polymorphism in the first intron of the spontaneously hypertensive rat renin gene. RFLP, SHR, WKY
76  1994 Analbuminemia does not significantly influence hepatocarcinogenesis on comparing F344 rats and a congenic line carrying the analbuminemic mutation. 2-AAF, DEN, HPN
77  1994 Early lead challenge and subsequent hypertension in Sprague-Dawley rats. BW, HT, SBP
78  1994 In vivo study of angiotensin II tachyphylaxis in freely moving normo- and hypertensive rats. DOCA, LRAS, MAP, SHR
79  1994 Inferior colliculus neuronal membrane and synaptic properties in genetically epilepsy-prone rats. GEPR, ICd
80  1993 A new model to evaluate the hypertensive response to noxious stimuli in the anesthetized, spontaneously hypertensive rat. SHR
81  1993 Comparison of hepatocyte phenotypes at the glutathione transferase and albumin loci in Sprague-Dawley and Nagase analbuminemic rats and F1 progeny after initiation and promotion. AHF, DMBA, NA, PB, PGST
82  1992 Both peripheral chylomicron catabolism and hepatic uptake of remnants are defective in nephrosis. CM, HN, TG
83  1992 Early breakdown of dendritic bundles in the retrosplenial granular cortex of hypertensive rats: prevention by antihypertensive therapy. Rg, SHR
84  1992 Impaired learning and memory in mature spontaneously hypertensive rats. SHR
85  1992 Nuclear DNA content and nucleation patterns in rat cardiac myocytes from different models of cardiac hypertrophy. AC, MI, PS, SHR
86  1992 Plasma IgG pool is not defended from urinary loss in nephrotic syndrome. HN, IgG, NAR
87  1992 [Studies on caries of Ishibashi rat--III. Experimental caries in Ishibashi rat]. ISR
88  1988 Serum lipids in spontaneously hypertensive rats and Sprague-Dawley rats fed menhaden oil. BP, Chol, CO, HDL-chol, LDL-chol, MO, SHR, TG
89  1987 Reversal of ischemic liver failure by intrasplenic liver cell transplantation. ---
90  1986 Cytoplasmic free [Ca2+] is not increased in the platelets of deoxycorticosterone-salt and spontaneously hypertensive rats. DOC, SHR, WKY
91  1986 Different susceptibilities to cerebral infarction in spontaneously hypertensive (SHR) and normotensive Sprague-Dawley rats. MCA, SHR
92  1985 Loss of accommodation in sympathetic neurons from spontaneously hypertensive rats. SHR, WKY
93  1985 Low susceptibility of analbuminemic rats to induction of bladder cancer by N-[4-(5-nitro-2-furyl)-2-thiazolyl]formamide. FANFT
94  1984 Lipogenesis from U14C lactate in obese Zucker rat hepatocytes. Effect of albumin-bound oleate. ---
95  1984 Role of arginine vasopressin in blood pressure control in young rats. AVP, DI, MAP
96  1983 Hypersensitivity of spontaneously hypertensive rats to heat and ether before the onset of high blood pressure. SHR
97  1983 The role of vasopressin in the maintenance of cardiovascular function during early endotoxin shock. ---
98  1983 [Passive enhancement of allogeneic rat kidney transplants with antibodies against nylon-adhering splenic lymphocytes]. ---
99  1981 Hypersensitivity of spontaneously hypertensive rats (SHR) to heat, ether, and immobilization. SHR