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Abbreviation : SD
Long Form : Sprague-Dawley
No. Year Title Co-occurring Abbreviation
2020 4-Nonylphenol and 4-tert-octylphenol induce anxiety-related behaviors through alternation of 5-HT receptors and transporters in the prefrontal cortex. 5-HT1A, 5-HT2A, 5-HT2C, EPM, MAOA, NP, OFT, OP, SERT, VAMT-2
2020 A combination of Semen Cuscutae and Fructus Lycii improves testicular cell proliferation and inhibits their apoptosis in rats with spermatogenic dysfunction by regulating the SCF/c-kit--PI3K--Bcl-2 pathway. FSH, GTW, H&E, LH, PRL, qRT-PCR, SC-FL
2020 Antibiotic Treatment Does Not Ameliorate the Metabolic Changes in Rats Presenting Dysbiosis After Consuming a High Fructose Diet. BP, TG
2020 Astragaloside IV alleviates ischemia reperfusion-induced apoptosis by inhibiting the activation of key factors in death receptor pathway and mitochondrial pathway. AS-IV, Cyto C
2020 Berberine decreases insulin resistance in a PCOS rats by improving GLUT4: Dual regulation of the PI3K/AKT and MAPK pathways. GLUT4, HOMA-IR, ISI, PCOS
2020 CB1 receptor antagonist rimonabant protects against chronic intermittent hypoxia-induced bone metabolism disorder and destruction in rats. CB1R, CIH, ECS, HE, IH, NC, OSA, Ri
2020 CGA restrains the apoptosis of Abeta25-35-induced hippocampal neurons. AD, CGA, ERS, GSH-Px, LDH, MDA, MMP, SOD, WB
2020 Ciprofibrate attenuates airway remodeling in cigarette smoke-exposed rats. ASM, CMap, COPD, CS
2020 Comparison of the inhibitory effect of ketoconazole, voriconazole, fluconazole, and itraconazole on the pharmacokinetics of bosentan and its corresponding active metabolite hydroxy bosentan in rats. BOS, OHBOS
10  2020 Decreased mesolimbicdopaminergic signaling underlies the waning of maternal caregiving across the postpartum period in rats. DA, LE, NA, VTA
11  2020 Ectopic osteogenesis by type I collagen loaded with a novel synthesized PTH-related peptide-1 in vivo. PTH
12  2020 Effect of rosiglitazone on myocardial injury in septic rats through NF-kappaB pathway. ELISA, EMSA, LDH, mRNA, NF-kappaB, qRT-PCR, TNF-alpha, TUNEL
13  2020 Epigenetic modification of H3K4 and oxidative stress are involved in MC-LR-induced apoptosis in testicular cells of SD rats. MC-LR, MTA, NAC, ROS
14  2020 Foodomics Revealed the Effects of Extract Methods on the Composition and Nutrition of Peanut Oil. CCA, GC-MS, LC-MS
15  2020 Four-week intravenous repeated dose toxicity study of vitacamphorae injection in rats. NOAEL, VCP
16  2020 Genome-wide transcriptional analysis of Aristolochia manshuriensis induced gastric carcinoma. AMK-10, CTL
17  2020 HMGB1 upregulates NF-kB by inhibiting IKB-alpha and associates with diabetic retinopathy. DM, DR, HMGB1, HREC, sh
18  2020 In Vitro and in Vivo Anti-Hyperglycemic Activities of Taxifolin and Its Derivatives Isolated from Pigmented Rice (Oryzae sativa L. cv. Superhongmi). CCC
19  2020 Influence of the pore size and porosity of selective laser melted Ti6Al4V ELI porous scaffold on cell proliferation, osteogenesis and bone ingrowth. ALP, BMP-2, COL1, OCN, OPN, rBM-MSCs, SLM
20  2020 Inhibition of microRNA-327 ameliorates ischemia/reperfusion injury-induced cardiomyocytes apoptosis through targeting apoptosis repressor with caspase recruitment domain. ARC, MI/RI, miRNAs
21  2020 Intake and preference for dried bonito dashi in male Sprague-Dawley rats and C57BL/6 N mice. ---
22  2020 Microglia polarization of hippocampus is involved in the mechanism of Apelin-13 ameliorating chronic water immersion restraint stress-induced depression-like behavior in rats. CWIRS
23  2020 MicroRNA-29b-3p aggravates 1,2-dichloroethane-induced brain edema by targeting aquaporin 4 in Sprague-Dawley rats and CD-1 mice. 1,2-DCE, AQP4, miR-29b
24  2020 miR-181b-5p inhibits endothelial-mesenchymal transition in monocrotaline-induced pulmonary arterial hypertension by targeting endocan and TGFBR1. EndMT, I-EndMT, MCT, PAH, rPAECs
25  2020 Noncanonical Mechanisms for Direct Bone Marrow Generating Ang II (Angiotensin II) Predominate in CD68 Positive Myeloid Lineage Cells. ACE, BM
26  2020 Pb exposure induces an imbalance of excitatory and inhibitory synaptic transmission in cultured rat hippocampal neurons. DIV, GABAAR
27  2020 Preparation of ursolic acid-phospholipid complex by solvent-assisted grinding method to improve dissolution and oral bioavailability. DSC, PXRD, SEM, TEM, UA, UA-PC
28  2020 Promotion of Wound Healing and Prevention of Frostbite Injury in Rat Skin by Exopolysaccharide from the Arctic Marine Bacterium Polaribacter sp. SM1127. EPSs, HDFs
29  2020 Quinazolinone derivative BNUA-3 ameliorated [NDEA+2-AAF]-induced liver carcinogenesis in SD rats by modulating AhR-CYP1B1-Nrf2-Keap1 pathway. AhR
30  2020 Recombinant OX40 attenuates neuronal apoptosis through OX40-OX40L/PI3K/AKT signaling pathway following subarachnoid hemorrhage in rats. EBI, i.c.v, ReOX40, SAH, siRNA
31  2020 Renal sympathetic nerve activity regulates cardiovascular energy expenditure in rats fed high salt. DSS, RSNA
32  2020 Repression of microRNA-21 inhibits retinal vascular endothelial cell growth and angiogenesis via PTEN dependent-PI3K/Akt/VEGF signaling pathway in diabetic retinopathy. DR, miR-21, PTEN, RVEC, VEGF
33  2020 Retardation of Preputial Wound Healing in Rats with Hypospadias Induced by Flutamide. alpha-SM actin, STAT3, TGF-beta1
34  2020 Secreted Monocyte miR-27a, via Mesenteric Arterial Mas Receptor-eNOS Pathway, Causes Hypertension. BP, eNOS, EVs
35  2020 Simvastatin alleviated diabetes mellitus-induced erectile dysfunction in rats by enhancing AMPK pathway-induced autophagy. CN, CSMCs, DMED, STZ
36  2020 Systems pharmacology-based study of Tanreqing injection in airway mucus hypersecretion. IL, LPS, MH, TNF-alpha, TRQ
37  2020 The effects of triptolide on the cellular activity of cryopreserved rat sciatic nerves and nerve regeneration after allotransplantation. DMEM, NGF
38  2020 The expression of miR-125b in Nrf2-silenced A549 cells exposed to hyperoxia and its relationship with apoptosis. BPD, miR-125b, Nrf2, qRT-PCR, siRNA
39  2020 The seed of Litchi chinensis fraction ameliorates hippocampal neuronal injury in an Abeta25-35-induced Alzheimer's disease rat model via the AKT/GSK-3beta pathway. AD, SLF
40  2020 The therapeutic effects of Stauntonia hexaphylla in benign prostate hyperplasia are mediated by the regulation of androgen receptors and 5alpha-reductase type 2. ARs, BPH, DHT, IHC, PCNA, PSA
41  2020 The Underlying Mechanisms of Curcumin Inhibition of Hyperglycemia and Hyperlipidemia in Rats Fed a High-Fat Diet Combined With STZ Treatment. AST, FBG, HDL-C, LDL-C, MDA, SOD, STZ, TC, TG
42  2020 Thermogelling chitosan-based polymers for the treatment of oral mucosa ulcers. CS-g-PNIPAAM, CS-g-PNIPAAM-g-PAM
43  2020 Transplantation of microencapsulated olfactory ensheathing cells inhibits the P2X2 receptor over-expression mediated neuropathic pain in the L4-5 spinal cord segment. CCI, MC-OECs, MWT, NPP, OECs, P2X2R
44  2020 Tsantan Sumtang attenuated chronic hypoxia-induced right ventricular structure remodeling and fibrosis by equilibrating local ACE-AngII-AT1R/ACE2-Ang1-7-Mas axis in rat. ACE, ACE2, Ang 1-7, Ang II, AT1R, CPA, ELISA, HE, HPAH, HR, Mas, mPAP, PSR, RV, RVHI, RVSP, TL
45  2020 TUDCA Ameliorates Liver Injury Via Activation of SIRT1-FXR Signaling in a Rat Hemorrhagic Shock Model. BA, HS, SIRT1, TUDCA
46  2020 Two thalidomide analogs induce persistent estrous behavior and inhibit uterus contractility in rats: The central role of cAMP. AC, cAMP, i.c.v, MAPK, PKA, Tha
47  2020 Urolithin B improves cardiac function and reduces susceptibility to ventricular arrhythmias in rats after myocardial infarction. BNP, MI, PBS, UB
48  2020 [The Establishment of a Three-color Flow Cytometry Approach for the Scoring of Micronucleated Reticulocytes in Rat Bone Marrow]. COL, CP, EMS, ENU, FITC, MNRETs, PE, RETs
49  2019 1H NMR toxicometabolomics following cisplatin-induced nephrotoxicity in male rats. CP, i.p, OPLS-DA, PCA
50  2019 3-Aminobenzamide protects against cerebral artery injury and inflammation in rats with intracranial aneurysms. 3-AB, HE, IA
51  2019 68Ga-Glutathione radio-complex as a new diagnostic probe for targeting colon cancer in rats. 68Ga, DMH
52  2019 A 90-day subchronic toxicology screen of genetically modified rice Lac-3 and its effects on the gut microbiota in Sprague-Dawley rats. GM, hLF, LF
53  2019 A Causal Relationship in Spinal Cord Injury Rat Model Between Microglia Activation and EGFR/MAPK Detected by Overexpression of MicroRNA-325-3p. EGFR, IL-1beta, LPS, MAPK, SCI, TNF-alpha
54  2019 A novel approach based on metabolomics coupled with network pharmacology to explain the effect mechanisms of Danggui Buxue Tang in anaemia. AA, BD, DBT, PC, PPI
55  2019 A novel approach to devise the therapy for ventricular fibrillation by epicardial delivery of lidocaine using active hydraulic ventricular attaching support system: An experimental study in rats. ANOVA, ECG, EI, VF
56  2019 A novel bionic in vitro bioelectronic tongue based on cardiomyocytes and microelectrode array for bitter and umami detection. BioETs, ETs, MEAs, PCA
57  2019 A novel immunodeficient rat model supports human lung cancer xenografts. CRISPR, PDX
58  2019 A novel manganese chelated macromolecular MRI contrast agent based on O-carboxymethyl chitosan derivatives. CMCS, Mn, MRI
59  2019 A novel methodology for rat aortic pulse wave velocity assessment by Doppler ultrasound: validation against invasive measurements. hfPWVE, cfPWVE, PWV
60  2019 A Novel Technology for Free Flap Monitoring: Pilot Study of a Wireless, Biodegradable Sensor. ---
61  2019 A scrutiny of circulating microRNA biomarkers for drug-induced tubular and glomerular injury in rats. AKI, BUN, Cre
62  2019 A study on regulatory mechanism of miR-223 in ulcerative colitis through PI3K/Akt-mTOR signaling pathway. ELISA, IL-1beta, miR, mTOR, p-Akt, PI3K, qPCR, TUNEL, UC
63  2019 A Systematic Study of Vascular Distribution Characteristics and Axis Design of Various Flap Types. ---
64  2019 A Traditional Clinic Chinese Medicine Prescription Qu-Zhuo-Tong-Bi (QZTB) Alleviates Gouty Arthritis in Model Rats. ELISA, MSU, QZTB
65  2019 Abnormal expression of HSP70 may contribute to PCOS pathology. CRP, DHEA, ELISA, FSH, HSP, IL, LH, PCOS, TNF
66  2019 Addition of the Aldose Reductase Inhibitor Benzofuroxane Derivative BF-5m to Prolonged and Moderate Exercise Training Enhanced Protection of the Rat Heart From Type-1 Diabetes. LVEF, MnSOD, SERCA2
67  2019 Adiponectin improves isoflurane-induced cognitive dysfunction in elderly rats via inhibiting p38-MAPK signal pathway in hippocampus. MAPK, RT-PCR
68  2019 AdipoRon prevents l-thyroxine or isoproterenol-induced cardiac hypertrophy through regulating the AMPK-related pathway. BW, HW, ISO, LV
69  2019 Aerobic Exercise Ameliorates Myocardial Inflammation, Fibrosis and Apoptosis in High-Fat-Diet Rats by Inhibiting P2X7 Purinergic Receptors. HE, HFD, P2X7R, PA
70  2019 Age-dependent differences on neurochemistry and behavior in rats raised with low and high levels of maternal care. LG
71  2019 AICAR, an AMPK activator, protects against cisplatin-induced acute kidney injury through the JAK/STAT/SOCS pathway. AICAR, AKI, AMPK, BUN
72  2019 Alamandine protects rat from myocardial ischemia-reperfusion injury by activating JNK and inhibiting NF-kappaB. IRI, IRI group, JNK, NF-kappaB, Sham group
73  2019 Alleviation of impaired reactivity in the corpus cavernosum of STZ-diabetic rats by slow-release H2S donor GYY4137. CC, NO, PE
74  2019 Alleviation of sepsis‑induced cardiac dysfunction by overexpression of Sestrin2 is associated with inhibition of p‑S6K and activation of the p‑AMPK pathway. cTnT, LPS, MDA
75  2019 Allicin disrupts cardiac Cav1.2 channels via trafficking. CMs
76  2019 Alphalipoic Acid Prevents Oxidative Stress and Peripheral Neuropathy in Nab-Paclitaxel-Treated Rats through the Nrf2 Signalling Pathway. alpha-LA, DRG, MDA, nab-PTX, PTX, SOD
77  2019 Alteration in behavior of rat after chronic exposure to acetamiprid. nAChR
78  2019 Ameliorative Effects of Probiotic Lactobacillus paracasei NL41 on Insulin Sensitivity, Oxidative Stress, and Beta-Cell Function in a Type 2 Diabetes Mellitus Rat Model. HFD/STZ, T2DM
79  2019 An alternating polarity switching assay for quantification of oxycodone and topiramate: An application of LC-MS/MS method in support to PK/PD study in rodents. MRM
80  2019 Analysis of haemodynamics and angiogenic response to ischaemia in the obese type 2 diabetic model Spontaneously Diabetic Torii Leprfa (SDT fatty) rats. PAD, SDT fatty
81  2019 Andrographolide enhances hippocampal BDNF signaling and suppresses neuronal apoptosis, astroglial activation, neuroinflammation, and spatial memory deficits in a rat model of chronic cerebral hypoperfusion. 2VO, BDNF, caspase-3, CCH, GFAP, HE, IL-1beta, TNF-alpha
82  2019 Angiotensin-(1-12)/chymase axis modulates cardiomyocyte L-type calcium currents in rats expressing human angiotensinogen. Ang II, ICa-L, RAS
83  2019 Anti-Inflammatory Effects of Step Electrical Stimulation on Complete Freund's Adjuvant (CFA) Induced Rheumatoid Arthritis Rats. CFA, COX-2, IL-6, SES, TNF-alpha
84  2019 Anti-Inflammatory Response and Muscarinic Cholinergic Regulation during the Laxative Effect of Asparagus cochinchinensis in Loperamide-Induced Constipation of SD Rats. AChE, Lop, MLC, SPA
85  2019 Anti-renal fibrosis effect of asperulosidic acid via TGF-beta1/smad2/smad3 and NF-kappaB signaling pathways in a rat model of unilateral ureteral obstruction. alpha-SMA, ASPA, ECM, IFN-gamma, IL-1beta, MCP-1, NF-kappaB, TGF-beta1, TNF-alpha, UA, Upro, UUO
86  2019 Artesunate induces mitochondria-mediated apoptosis of human retinoblastoma cells by upregulating Kruppel-like factor 6. ART, ERG, FFA, KLF6, OCT, Rb
87  2019 Assessment of Biopharmaceutical Performance of Supersaturating Formulations of Carbamazepine in Rats Using Physiologically Based Pharmacokinetic Modeling. CBZ, PBPK, SDDS
88  2019 Assessment of mulberry leaf as a potential feed supplement for animal feeding in P.R. China. BW
89  2019 Astragaloside IV combating liver cirrhosis through the PI3K/Akt/mTOR signaling pathway. ALT, AS-IV, AST, CMC, ELISA, IL, mTOR, PI3K, TNF-alpha
90  2019 Astragaloside IV protects against diabetic nephropathy via activating eNOS in streptozotocin diabetes-induced rats. AS-IV, BUN, DN, eNOS, HE, HG, HRGECs, NO, PAS, SCr, STZ
91  2019 Astragaloside IV protects against hyperglycemia-induced vascular endothelial dysfunction by inhibiting oxidative stress and Calpain-1 activation. AS-IV, ED, STZ
92  2019 Atorvastatin improves the cardiac function of rats after acute myocardial infarction through ERK1/2 pathway. AMI, ATV, ECG, ERK, HE, LVWI, MRI, mRNA, PCR, TUNEL
93  2019 Behavioral Diversity Across Classic Rodent Models Is Sex-Dependent. CS, PTSD, SFS
94  2019 Bilobetin induces kidney injury by influencing cGMP-mediated AQP-2 trafficking and podocyte cell cycle arrest. AQP2, GB
95  2019 Biodegradability and Safety Study of LifeMesh™, a Novel Self-adhesive Mesh, in Sprague-Dawley Rats. BPP
96  2019 Brain functions and unusual beta-amyloid accumulation in the hypertensive white matter lesions of rats. APP, BACE1, ELISA, H and E, RHRSP, WML
97  2019 Brain region-specific effects of long-term caloric restriction on redox balance of the aging rat. AL, CR
98  2019 Celastrol inhibits microglial pyroptosis and attenuates inflammatory reaction in acute spinal cord injury rats. LPS, SCI
99  2019 Celecoxib Protects Hyperoxia-Induced Lung Injury via NF-kappaB and AQP1. AQP, BDP
100  2019 Changes and Significance of SYP and GAP-43 Expression in the Hippocampus of CIH Rats. CIH, CON, GAP-43, SYP