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[Related PubMed/MEDLINE] Total Number of Papers: 377
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Abbreviation |
: SGK1 |
Long Form |
: serum- and glucocorticoid-inducible kinase 1 |
|
No. |
Year |
Title |
Co-occurring Abbreviation |
1 |
2020 |
Acute Hyperglycemia Aggravates Lung Injury via Activation of the SGK1-NKCC1 Pathway. |
ALI, AM, SPAK |
2 |
2020 |
Anti-invasive effect and pharmacological mechanism of genistein against colorectal cancer. |
CRC, lncRNA, TGF-beta1 |
3 |
2020 |
Behavioral effects of SGK1 knockout in VTA and dopamine neurons. |
DA, KO, VTA |
4 |
2020 |
Bisphenol A-induced mechanistic impairment of decidualization. |
BPA, Egr-1, eNOS, ER, NO, PR |
5 |
2020 |
CASZ1b is a novel transcriptional corepressor of mineralocorticoid receptor. |
ENaCalpha, MR |
6 |
2020 |
Circular RNA circ_0007142 regulates cell proliferation, apoptosis, migration and invasion via miR-455-5p/SGK1 axis in colorectal cancer. |
circ_0007142, CRC, miR-455-5p |
7 |
2020 |
Clinical characteristics of colorectal cancer patients and anti-neoplasm activity of genistein. |
Bcl-2, CRC, Erk1, LDH, TUNEL |
8 |
2020 |
Combination therapy with mTOR kinase inhibitor and dasatinib as a novel therapeutic strategy for vestibular schwannoma. |
MN, NF2, SCs, VS |
9 |
2020 |
Discovery of a novel rhein-SAHA hybrid as a multi-targeted anti-glioblastoma drug. |
CNS, GBM, HDAC, SAHA |
10 |
2020 |
Genome-wide integration of microRNA and transcriptomic profiles of differentiating human alveolar epithelial cells. |
AT1, hAT2, miRNAs |
11 |
2020 |
Glucocorticoid induces human beta cell dysfunction by involving riborepressor GAS5 LincRNA. |
DM, GC, HREM |
12 |
2020 |
Glucocorticoid receptor and serum- and glucocorticoid-induced kinase-1 in esophageal adenocarcinoma and adjacent Barrett's esophagus. |
BE, EAC, GR |
13 |
2020 |
Glucocorticoids and serum- and glucocorticoid-inducible kinase 1 are potent regulators of CFTR in the native intestine: implications for stress-induced diarrhea. |
cAMP, cGMP, DEXA, GC, Nedd4-2, PI3K |
14 |
2020 |
GR, Sgk1, and NDRG1 in esophageal squamous cell carcinoma: their correlation with therapeutic outcome of neoadjuvant chemotherapy. |
DFS, ESCC, GC, NAC, NDRG1, OS |
15 |
2020 |
Hippocampal overexpression of SGK1 ameliorates spatial memory, rescues Abeta pathology and actin cytoskeleton polymerization in middle-aged APP/PS1 mice. |
AD, oSGK1 |
16 |
2020 |
Knockdown of SGK1 alleviates the IL-1beta-induced chondrocyte anabolic and catabolic imbalance by activating FoxO1-mediated autophagy in human chondrocytes. |
FOXO1, IL-1beta, OA |
17 |
2020 |
Low Circulating Levels of GR, FKBP5, and SGK1 in Medicated Patients With Depression Are Not Altered by Electroconvulsive Therapy. |
ECT, GC, GR |
18 |
2020 |
Monocyte Chemotactic Protein-1 Regulates Proliferation and Contractility of Human Bladder Smooth Muscle Cells Under Hydrostatic Pressure. |
hBSMCs, HP, MCP-1, MCPIP1, PBOO, rhMCP-1, ROS |
19 |
2020 |
PO-322 exerts potent immunosuppressive effects in vitro and in vivo by selectively inhibiting SGK1 activity. |
DTH |
20 |
2020 |
Role of SGK1 in the Osteogenic Transdifferentiation and Calcification of Vascular Smooth Muscle Cells Promoted by Hyperglycemic Conditions. |
AGEs, VSMCs |
21 |
2020 |
Salt Sensing by Serum/Glucocorticoid-Regulated Kinase 1 Promotes Th17-like Inflammatory Adaptation of Foxp3+ Regulatory T Cells. |
HS, Treg |
22 |
2020 |
Serum- and glucocorticoid-induced kinase 1, a new therapeutic target for autophagy modulation in chronic diseases. |
--- |
23 |
2020 |
Serum- and glucocorticoid-inducible kinase 1 activity reduces dendritic spines in dorsal hippocampus. |
--- |
24 |
2020 |
Serum- and Glucocorticoid-inducible Kinase 1 is Essential for Osteoclastogenesis and Promotes Breast Cancer Bone Metastasis. |
--- |
25 |
2020 |
SGK1 activation exacerbates diet-induced obesity, metabolic syndrome and hypertension. |
MetS |
26 |
2020 |
SGK1 mediates the hypotonic protective effect against H2O2-induced apoptosis of rat basilar artery smooth muscle cells by inhibiting the FOXO3a/Bim signaling pathway. |
BASMCs, Bim, FOXO3a, MMP, VRCCs |
27 |
2020 |
Significance of glucocorticoid signaling in triple-negative breast cancer patients: a newly revealed interaction with androgen signaling. |
11beta-HSD, DEX, DHT, GCs, GR, AR, TNBC |
28 |
2020 |
Sodium butyrate ameliorates deoxycorticosterone acetate/salt-induced hypertension and renal damage by inhibiting the MR/SGK1 pathway. |
DOCA, MR, SD |
29 |
2020 |
Targeting SGK1 enhances the efficacy of radiotherapy in locally advanced rectal cancer. |
ATF3, IHC, LARC, non-pCR, RT |
30 |
2020 |
TCRP1 induces tamoxifen resistance by promoting the activation of SGK1 in MCF‑7 cells. |
ER, PDK1, TCRP1 |
31 |
2020 |
The Emerging Role of SGK1 (Serum- and Glucocorticoid-Regulated Kinase 1) in Major Depressive Disorder: Hypothesis and Mechanisms. |
BDNF, HPA, MDD, VEGF |
32 |
2020 |
The functional duality of SGK1 in the regulation of hyperglycemia. |
--- |
33 |
2020 |
The prospect of serum and glucocorticoid-inducible kinase 1 (SGK1) in cancer therapy: a rising star. |
mTOR, PI3K |
34 |
2020 |
Transcriptome sequencing identifies genes associated with invasion of ovarian cancer. |
AKT3, ANGPT2, CD19, CSF3, DEGs, FGF-1, FGF18, ITGA11, ITGA2, ITGB4, ITGB8, LAMA3, MYB, PCK2, PGF, PIK3AP1, SYK, TLR4, TP53 |
35 |
2020 |
Upregulation of serum and glucocorticoid-regulated kinase 1 exacerbates brain injury and neurological deficits after cardiac arrest. |
ACA, CA |
36 |
2020 |
Urethral meatus stricture BOO stimulates bladder smooth muscle cell proliferation and pyroptosis via IL‑1beta and the SGK1‑NFAT2 signaling pathway. |
BOO, MBSMC |
37 |
2020 |
Virtual Screening Approach to Identify High-Affinity Inhibitors of Serum and Glucocorticoid-Regulated Kinase 1 among Bioactive Natural Products: Combined Molecular Docking and Simulation Studies. |
ADMET |
38 |
2019 |
Acupuncture Inhibits the Increase in Alpha-Synuclein by Modulating SGK1 in an MPTP Induced Parkinsonism Mouse Model. |
MPTP, PD, SN |
39 |
2019 |
Administration of dexamethasone disrupts endometrial receptivity by alteration of expression of miRNA 223, 200a, LIF, Muc1, SGK1, and ENaC via the ERK1/2-mTOR pathway. |
ENaC, LIF, mTOR |
40 |
2019 |
Association of SGK1 Polymorphisms With Susceptibility to Coronary Heart Disease in Chinese Han Patients With Comorbid Depression. |
CHD, CI, OR, PCR-LDR, PHQ-9, SNPs |
41 |
2019 |
Celastrol suppresses experimental autoimmune encephalomyelitis via MAPK/SGK1-regulated mediators of autoimmune pathology. |
BDNF, EAE, MAPK, MOG, MS, Th17, Treg |
42 |
2019 |
Comprehensive analysis of microRNA-messenger RNA regulatory network in gemcitabine-resistant bladder cancer cells. |
DEGs, miRNAs, PPI, qRT-PCR |
43 |
2019 |
Computational insights into the active structure of SGK1 and its implication for ligand design. |
--- |
44 |
2019 |
Effects of the Ethanol Extract of Dipterocarpus alatus Leaf on the Unpredictable Chronic Mild Stress-Induced Depression in ICR Mice and Its Possible Mechanism of Action. |
BDNF, CREB, FST, HPA, MAO, TST, UCMS |
45 |
2019 |
Glucocorticoid stimulation increases cardiac contractility by SGK1-dependent SOCE-activation in rat cardiac myocytes. |
Ca, DEX, GC, SOCE |
46 |
2019 |
Impact of Zn2+ on ABC Transporter Function in Intact Isolated Rat Brain Microvessels, Human Brain Capillary Endothelial Cells, and in Rat in Vivo. |
BBB, BCRP, ETB, MRP2, mTOR, NOS, P-gp, PI3K, PKC, Zn |
47 |
2019 |
In Preclinical Model of Ovarian Cancer, the SGK1 Inhibitor SI113 Counteracts the Development of Paclitaxel Resistance and Restores Drug Sensitivity. |
Sp1 |
48 |
2019 |
Insulin ameliorates pulmonary edema through the upregulation of epithelial sodium channel via the PI3K/SGK1 pathway in mice with lipopolysaccharide‑induced lung injury. |
ALI, ENaC, LPS, PI3K, siRNA |
49 |
2019 |
Intracarotid cold saline infusion contributes to neuroprotection in MCAO‑induced ischemic stroke in rats via serum and glucocorticoid‑regulated kinase 1. |
ICSI, IOD, MCAO |
50 |
2019 |
Investigation of the underling mechanism of ketamine for antidepressant effects in treatment-refractory affective disorders via molecular profile analysis. |
Dcaf12l1, DEGs, KLF2, Plin4, PPIs |
51 |
2019 |
Jixuepaidu Tang-1 inhibits epithelial-mesenchymal transition and alleviates renal damage in DN mice through suppressing long non-coding RNA LOC498759. |
DN, EMT, HG, lnRNAs, TGF-beta1 |
52 |
2019 |
Leonurine promotes neurite outgrowth and neurotrophic activity by modulating the GR/SGK1 signaling pathway in cultured PC12 cells. |
Bcl-2, BDNF, GR, NT-3 |
53 |
2019 |
Lovastatin attenuates hypertension induced by renal tubule-specific knockout of ATP-binding cassette transporter A1, by inhibiting epithelial sodium channels. |
CCD, ENaC, Nedd4-2 |
54 |
2019 |
p38MAPK/SGK1 signaling regulates macrophage polarization in experimental autoimmune encephalomyelitis. |
AAV, EAE, MAPK, MS |
55 |
2019 |
Perfluorooctanoic acid induces migration and invasion and inhibits apoptosis through the PI3K/AKT signaling pathway in human rhabdomyosarcoma cells. |
CDK, PFOA, PI3K, RMS |
56 |
2019 |
Postnatal gene expression of airway epithelial sodium transporters associated with birth stress in humans. |
AQP, ENaC |
57 |
2019 |
Quantitative proteomic analyses of dynamic signalling events in cortical neurons undergoing excitotoxic cell death. |
Akt, Cdk5, CK2, GSK-3, iGluRs, JNK, MEK, Rock |
58 |
2019 |
Radiation-induced glucocorticoid receptor promotes CD44+ prostate cancer stem cell growth through activation of SGK1-Wnt/beta-catenin signaling. |
CSC, GR, PCa |
59 |
2019 |
Rosiglitazone promotes ENaC-mediated alveolar fluid clearance in acute lung injury through the PPARgamma/SGK1 signaling pathway. |
AFC, ALI, ARDS, BALF, ENaC, LPS, PPARgamma |
60 |
2019 |
SGK1 Attenuates Oxidative Stress-Induced Renal Tubular Epithelial Cell Injury by Regulating Mitochondrial Function. |
ATP, ROS |
61 |
2019 |
SGK1 Mediates Hypoxic Pulmonary Hypertension through Promoting Macrophage Infiltration and Activation. |
PAH, RVHI, RVSP |
62 |
2019 |
SGK1 protein expression is a prognostic factor of lung adenocarcinoma that regulates cell proliferation and survival. |
--- |
63 |
2019 |
SGK1-dependent stimulation of vascular smooth muscle cell osteo-/chondrogenic transdifferentiation by interleukin-18. |
ALPL, HAoSMCs, IL-18, VSMCs |
64 |
2019 |
Small nucleolar RNA host gene 1 promotes development and progression of colorectal cancer through negative regulation of miR-137. |
CRC, FCM, RISC, SNHG1 |
65 |
2019 |
Spinal Serum- and Glucocorticoid-Regulated Kinase 1 (SGK1) Signaling Contributes to Morphine-Induced Analgesic Tolerance in Rats. |
NF-kappaB, NMDARs |
66 |
2019 |
Targeting of SGK1 by miR-576-3p Inhibits Lung Adenocarcinoma Migration and Invasion. |
NDRG1 |
67 |
2019 |
The GCs-SGK1-ATP Signaling Pathway in Spinal Astrocytes Underlied Presurgical Anxiety-Induced Postsurgical Hyperalgesia. |
ATP, FC, RU486, SPS |
68 |
2019 |
Trichostatin A blocks aldosterone-induced Na+ transport and control of serum- and glucocorticoid-inducible kinase 1 in cortical collecting duct cells. |
CCD, ENaC |
69 |
2018 |
A Large-Scale RNAi Screen Identifies SGK1 as a Key Survival Kinase for GBM Stem Cells. |
GBM, GBM-SC |
70 |
2018 |
Aldosterone, SGK1, and ion channels in the kidney. |
ASDN, MR |
71 |
2018 |
Could Sodium Chloride be an Environmental Trigger for Immune-Mediated Diseases? An Overview of the Experimental and Clinical Evidence. |
ACPA, CD, IL-23R, IMDs, MS, RA, Th |
72 |
2018 |
Decreased expression of serum- and glucocorticoid-inducible kinase 1 (SGK1) promotes alpha-synuclein increase related with down-regulation of dopaminergic cell in the Substantia Nigra of chronic MPTP-induced Parkinsonism mice and in SH-SY5Y cells. |
alpha-syn, MPTP, PD, SN |
73 |
2018 |
Environmentally relevant levels of bisphenol A affect uterine decidualization and embryo implantation through the estrogen receptor/serum and glucocorticoid-regulated kinase 1/epithelial sodium ion channel alpha-subunit pathway in a mouse model. |
BPA, ENaCalpha |
74 |
2018 |
Increased intracellular Cl- concentration promotes ongoing inflammation in airway epithelium. |
CFTR, LPS, NF-kappaB |
75 |
2018 |
Inflammation in Salt-Sensitive Hypertension and Renal Damage. |
BP, DCs, IFN-gamma, IL-17a, TNF-alpha |
76 |
2018 |
Inhibitors of the proteasome stimulate the epithelial sodium channel (ENaC) through SGK1 and mimic the effect of aldosterone. |
ASDN, ENaC |
77 |
2018 |
Knockdown of Long Non-Coding RNA XIST Inhibited Doxorubicin Resistance in Colorectal Cancer by Upregulation of miR-124 and Downregulation of SGK1. |
CRC, DOX, GST-pi, P-gp, XIST |
78 |
2018 |
Knockdown of the long non-coding RNA HOTTIP inhibits colorectal cancer cell proliferation and migration and induces apoptosis by targeting SGK1. |
CRC, lncRNA |
79 |
2018 |
Mechanisms Underpinning Adaptations in Placental Calcium Transport in Normal Mice and Those With Fetal Growth Restriction. |
FGR, LvH, PTHrP, WT, WTL |
80 |
2018 |
N-Myc Downstream-Regulated Gene 1 Restricts Hepatitis C Virus Propagation by Regulating Lipid Droplet Biogenesis and Viral Assembly. |
HCV, NDRG1 |
81 |
2018 |
Na+ /H+ exchanger 3 blockade ameliorates type 2 diabetes mellitus via inhibition of sodium-glucose co-transporter 1-mediated glucose absorption in the small intestine. |
BBM, NHE3, SGLT1, T2DM |
82 |
2018 |
Regulation of Kv1.4 potassium channels by PKC and AMPK kinases. |
AMPK, MDCK, PI3K, PKC |
83 |
2018 |
Role of PKB/SGK-dependent phosphorylation of GSK-3alpha/beta in vascular calcification during cholecalciferol overload in mice. |
ALPL, GSK-3, gsk-3KI, PAI-1, PKB |
84 |
2018 |
Salt, inflammatory joint disease, and autoimmunity. |
--- |
85 |
2018 |
Serum and glucocorticoid-regulated kinase 1 (SGK1) is a predictor of poor prognosis in non-small cell lung cancer, and its dynamic pattern following treatment with SGK1 inhibitor and gamma-ray irradiation was elucidated. |
--- |
86 |
2018 |
Serum- and glucocorticoid-inducible kinase 1 and the response to cell stress. |
AP-1, CREB, FOXO3a, mTOR, NCC, NF-kappaB, PDK1, PI3K |
87 |
2018 |
Serum-glucocorticoid-regulated kinase 1 contributes to mechanical stretch-induced inflammatory responses in cardiac fibroblasts. |
NF-kappaB, WT |
88 |
2018 |
Serum/glucocorticoid-regulated kinase 1 as a novel transcriptional target of bone morphogenetic protein-ALK1 receptor signaling in vascular endothelial cells. |
BMP9 |
89 |
2018 |
SGK1 Governs the Reciprocal Development of Th17 and Regulatory T Cells. |
--- |
90 |
2018 |
SGK1 induces vascular smooth muscle cell calcification through NF-kappaB signaling. |
CKD, VSMCs |
91 |
2018 |
SGK1 Inhibits Autophagy in Murine Muscle Tissue. |
LC3 |
92 |
2018 |
SGK1 inhibits PM2.5-induced apoptosis and oxidative stress in human lung alveolar epithelial A549 cells. |
PM2.5, ROS |
93 |
2018 |
SGK1-FoxO1 Signaling Pathway Mediates Th17/Treg Imbalance and Target Organ Inflammation in Angiotensin II-Induced Hypertension. |
Ang II, FOXO1, TNF-alpha |
94 |
2018 |
SGK1/FOXO3 Signaling in Hypothalamic POMC Neurons Mediates Glucocorticoid-Increased Adiposity. |
alpha-MSH, DEX, POMC |
95 |
2018 |
The Disease-modifying Drug Candidate, SAK3 Improves Cognitive Impairment and Inhibits Amyloid beta Deposition in App Knock-in Mice. |
AD |
96 |
2018 |
The phosphorylation site T613 in the beta-subunit of rat epithelial Na+ channel (ENaC) modulates channel inhibition by Nedd4-2. |
ENaC, ERK |
97 |
2017 |
Akt3 inhibits adipogenesis and protects from diet-induced obesity via WNK1/SGK1 signaling. |
--- |
98 |
2017 |
Akt3 kinase suppresses pinocytosis of low-density lipoprotein by macrophages via a novel WNK/SGK1/Cdc42 protein pathway. |
--- |
99 |
2017 |
Aldosterone Modulates the Association between NCC and ENaC. |
ALDO, ENaC |
100 |
2017 |
Aldosterone signaling regulates the over-expression of claudin-4 and -8 at the distal nephron from type 1 diabetic rats. |
ALD, HSP72, KIM-1, SPL, STZ, TJ, WT1 |
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