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Abbreviation : SOS1
Long Form : Son of sevenless homolog 1
No. Year Title Co-occurring Abbreviation
2020 SOS1 Gain-of-Function Variants in Dilated Cardiomyopathy. CDC25, DCM, PR
2019 Enhanced expression of son of sevenless homolog 1 is predictive of poor prognosis in uveal malignant melanoma patients. UM
2019 KRAS and EGFR Amplifications Mediate Resistance to Rociletinib and Osimertinib in Acquired Afatinib-Resistant NSCLC Harboring Exon 19 Deletion/T790M in EGFR. Grb2, TKI
2018 Discovery and Structure-Based Optimization of Benzimidazole-Derived Activators of SOS1-Mediated Nucleotide Exchange on RAS. ---
2018 Discovery of Aminopiperidine Indoles That Activate the Guanine Nucleotide Exchange Factor SOS1 and Modulate RAS Signaling. GEF, MAPK-ERK, SAR
2018 Discovery of Quinazolines That Activate SOS1-Mediated Nucleotide Exchange on RAS. GEF, MAPK/ERK
2018 Protein X-ray crystallography of the 14-3-3zeta/SOS1 complex. ---
2018 Structural characterization of 14-3-3zeta in complex with the human Son of sevenless homolog 1 (SOS1). PPI
2018 [Research progress on pathophysiological function of SOS1 protein]. ---
10  2017 Identification and functional analysis of the risk microRNAs associated with cerebral low-grade glioma prognosis. GO, H-PGDS, LGGs, miR, miRNA, NRAS, PPI, SGMS1, VDR
11  2016 Identification of Potential Novel Biomarkers and Signaling Pathways Related to Otitis Media Induced by Diesel Exhaust Particles Using Transcriptomic Analysis in an In Vivo System. CD4, CHRM1, DEPs, EPO, ESR1, IFNA1, OM, PAHs
12  2016 MiR-20b Displays Tumor-Suppressor Functions in Papillary Thyroid Carcinoma by Regulating the MAPK/ERK Signaling Pathway. ERK2, MAPK/ERK, miRNAs, PTC
13  2015 miR-146a and miR-370 coordinate enterovirus 71-induced cell apoptosis through targeting SOS1 and GADD45beta. EV71, GADD45beta, MiRNAs, mRNAs
14  2014 Bufalin-inhibited migration and invasion in human osteosarcoma U-2 OS cells is carried out by suppression of the matrix metalloproteinase-2, ERK, and JNK signaling pathways. Grb2, MAPKs
15  2014 Genome-wide expression analysis of hereditary hyperplastic gingivitis in silver foxes (Vulpes vulpes) using canine microarrays. HGF, HHG
16  2014 Sequence analysis of the Ras-MAPK pathway genes SOS1, EGFR & GRB2 in silver foxes (Vulpes vulpes): candidate genes for hereditary hyperplastic gingivitis. EGFR, GRB2, HGF, HHG
17  2013 Quercetin inhibits migration and invasion of SAS human oral cancer cells through inhibition of NF-kappaB and matrix metalloproteinase-2/-9 signaling pathways. COX-2, FAK, Grb2, iNOS, MEKK3, MMP, NF-kappaB, PI3K, PKC, RAS, RhoA, ROCK1, uPA, VEGF
18  2012 RSK phosphorylates SOS1 creating 14-3-3-docking sites and negatively regulating MAPK activation. MAPK
19  2011 Gallic acid suppresses the migration and invasion of PC-3 human prostate cancer cells via inhibition of matrix metalloproteinase-2 and -9 signaling pathways. FAK, GA, Grb2, JNK, MMP-2, NF-kappaB, PI3K, PKC, TIMP1
20  2009 Enhanced expression of SOS1 is detected in prostate cancer epithelial cells from African-American men. AA, EA