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Abbreviation : SOST
Long Form : sclerostin
No. Year Title Co-occurring Abbreviation
2020 A Review of the Potential Application of Osteocyte-Related Biomarkers, Fibroblast Growth Factor-23, Sclerostin, and Dickkopf-1 in Predicting Osteoporosis and Fractures. BTMs, DKK1, FGF23
2020 BMP-induced Atoh8 attenuates osteoclastogenesis by suppressing Runx2 transcriptional activity and reducing the Rankl/Opg expression ratio in osteoblasts. Atoh8, BMP, OPG
2020 Can we enhance osteoporotic metaphyseal fracture healing through enhancing ultrastructural and functional changes of osteocytes in cortical bone with low-magnitude high-frequency vibration? BMD, DMP1, FGF23, LCN, LMHFV, MAR
2020 CCN1/Cyr61 is required in osteoblasts for responsiveness to the anabolic activity of PTH. PTH, PTH1R
2020 Circulating Osteocyte-Related Biomarkers (vitamin D, sclerostin, dickkopf-1), hepcidin, and oxidative stress markers in early breast cancer: their impact in disease progression and outcome. BC, DKK1
2020 Dentin Sialophosphoprotein Deletion Leads to Femoral Head Cartilage Attenuation and Subchondral Bone Ill-mineralization. DMP1, DSPP, TRAP, VEGF, WT
2020 Different Effects of Fluoride Exposure on the Three Major Bone Cell Types. BMSCs, TRACP
2020 Effect of fluoride on osteocyte-driven osteoclastic differentiation. OPG, PTH, RANKL
2020 Effects of 1-year anti-TNF-alpha therapies on bone mineral density and bone biomarkers in rheumatoid arthritis and ankylosing spondylitis. AS, BMD, CathK, CRP, CZP, DKK1, ETN, PTH, RA, sRANKL, TNF
10  2020 Effects of mild hyperbaric oxygen on osteoporosis induced by hindlimb unloading in rats. ---
11  2020 Establishment of in vitro three-dimensional cementocyte differentiation scaffolds to study orthodontic root resorption. OPG, RANKL
12  2020 Fibroblast-secreted trophic factors contribute with ECM remodeling stimulus and upmodulate osteocyte gene markers in osteoblasts. DMP1, ECM, MMP-9, OPG, RANKL, RECK
13  2020 Fructus Ligustri Lucidi preserves bone quality through induction of canonical Wnt/beta-catenin signaling pathway in ovariectomized rats. DKK1, FLL, GSK3beta
14  2020 In-depth proteomics approach reveals novel biomarkers of cardiac remodelling after myocardial infarction: An exploratory analysis. GDF15, LVEDVI, LVEF, MCP-3, MI, MK, uPA
15  2020 Interactions between Sclerostin and Glycosaminoglycans. GAG, rh, rm, SPR
16  2020 lncRNA MEG3 Suppresses the Progression of Ankylosis Spondylitis by Regulating the Let-7i/SOST Axis. AS, lncRNA, MEG3, qRT-PCR, RIP, WB
17  2020 Maxillary suture expansion: A mouse model to explore the molecular effects of mechanically-induced bone remodeling. ALP, Bmp-2, Col1a1, CTSK, DMP1, micro-CT, Mmp9 and 13, OCN, OPG, qPCR, RANK, RME
18  2020 Molecular Basis for Craniofacial Phenotypes Caused by Sclerostin Deletion. CT
19  2020 Osteoblast-Based Therapy-A New Approach for Bone Repair in Osteoporosis: Pre-Clinical Setting. BALP, BM-MSCs, BSP, OM, OPG, Osx, RANKL
20  2020 Sclerostin inhibits Wnt signaling through tandem interaction with two LRP6 ectodomains. LRP6
21  2020 Serum levels of leptin, osteopontin, and sclerostin in patients with and without knee osteoarthritis. KL, KOA, OPN
22  2020 Suppression of tooth movement-induced sclerostin expression using beta-adrenergic receptor blockers. beta-AR, RANKL, SHR
23  2020 The effects of decontamination methods of dental implant surface on cytokine expression analysis in the reconstructive surgical treatment of peri-implantitis. CAL, DF, IL, OPG, PICF, RST, VEGF
24  2020 The Effects of Sclerostin on the Immune System. ---
25  2020 Tissue-specific mesenchymal stem cell-dependent osteogenesis in highly porous chitosan-based bone analogs. AD-MSCs, ALP, BM-MSCs, BMP-4, Col I, MSCs, OCN, WJ-MSCs
26  2020 TRPV4 calcium influx controls sclerostin protein loss independent of purinergic calcium oscillations. NOX2
27  2019 Bone Matrix Levels of Dickkopf and Sclerostin are Positively Correlated with Bone Mass and Strength in Postmenopausal Osteoporosis. BMD, DKK1, Dkks
28  2019 Changes in Human Foetal Osteoblasts Exposed to the Random Positioning Machine and Bone Construct Tissue Engineering. ACTB, BMP2, COL1A1, ECM, FN1, IL-1beta, LAMA1, MCS, OC, OPG, OPN, RPM, s-g, SOX9, TNF-1alpha, VIM
29  2019 Deficiency of stress-associated gene Nupr1 increases bone volume by attenuating differentiation of osteoclasts and enhancing differentiation of osteoblasts. NUPR1
30  2019 Differences in Osteoimmunological Biomarkers Predictive of Psoriatic Arthritis among a Large Italian Cohort of Psoriatic Patients. AUC, CHI3L1, DKK1, MMPs, RANK-L, TIMPs
31  2019 Differential expression of periostin, sclerostin, receptor activator of nuclear factor-kappaB, and receptor activator of nuclear factor-kappaB ligand genes in severe chronic periodontitis. PCR, POSTN, RANK, RANKL
32  2019 Effects of different training modalities on phosphate homeostasis and local vitamin D metabolism in rat bone. CYP24, DMP1, FGF23, MEPE, PET, PHEX, PTH, VDR
33  2019 Evaluation of serum fibroblast growth factor-23 in patients with axial spondyloarthritis and its association with sclerostin, inflammation, and spinal damage. AS, axSpA, CRP, ESR, FGF23, HC, mSASSS
34  2019 Induction of Lrp5 HBM-causing mutations in Cathepsin-K expressing cells alters bone metabolism. DKK1, HBM, LRP5, NTG
35  2019 Isolation and characterization of a human cementocyte-like cell line, HCY-23. DMP1, Pi
36  2019 Low Serum Levels of DKK2 Predict Incident Low-Impact Fracture in Older Women. CRFs, DKK1, SFRP1
37  2019 Metformin protects bone mass in ultra-high-molecular-weight polyethylene particle-induced osteolysis by regulating osteocyte secretion. DKK1, OPG, RANKL
38  2019 Methylation of bone SOST impairs SP7, RUNX2, and ERalpha transactivation in patients with postmenopausal osteoporosis. ERalpha
39  2019 microRNA-96 promotes osteoblast differentiation and bone formation in ankylosing spondylitis mice through activating the Wnt signaling pathway by binding to SOST. ALP, AS, miR-96, miRNAs
40  2019 Primary Human Osteocyte Networks in Pure and Modified Collagen Gels. ALPL, DMP1, MEPE, PDPN, PHEX
41  2019 Relaxin 2 carried by magnetically directed liposomes accelerates rat midpalatal suture expansion and subsequent new bone formation. MPS, OF, POSTN, RLN
42  2019 Rheumatoid arthritis in remission : Decreased myostatin and increased serum levels of periostin. CRT, DKK1, FSTN, ICF, MSTN, PSTN, RA, TUG
43  2019 Sclerostin and WNT-5a gingival protein levels in chronic periodontitis and health. GCF
44  2019 Systemic investigation of bone and muscle abnormalities in dystrophin/utrophin double knockout mice during postnatal development and the mechanisms. RANKL, WT
45  2019 The Effects of Tocotrienol on Bone Peptides in a Rat Model of Osteoporosis Induced by Metabolic Syndrome: The Possible Communication between Bone Cells. DKK1, FGF23, HCHF, MetS, OPG, PTH, sRANKL
46  2019 The Influence of Pro-Inflammatory Factors on Sclerostin and Dickkopf-1 Production in Human Dental Pulp Cells Under Hypoxic Conditions. Dkk, DPC, IL, L-MIM, TGF, TNF
47  2019 The role of sclerostin and dickkopf-1 in oral tissues - A review from the perspective of the dental disciplines. Dkk
48  2019 Wnt Antagonists in Hematopoietic and Immune Cell Fate: Implications for Osteoporosis Therapies. HIF, Sostdc1, VHL
49  2019 [Effect of sclerostin on the functions and related mechanisms of cementoblasts under mechanical stress]. ALP, BMP, BSP, OCN, OPG, RANKL
50  2019 [Effects of bergapten on damages of osteocytes MLO-Y4 induced by TCP wear particles and its mechanism]. AFT4, BP, CHOP, DMP1, eIF2alpha, FGF23, GRP78, p-eIF2alpha, p-PERK, PERK, TCP
51  2018 Antagonists of Wnt/beta-catenin signalling in the periodontitis associated with type 2 diabetes and smoking. CP, Dkk, DM
52  2018 Bone metabolism in patients with anorexia nervosa and amenorrhoea. DXA
53  2018 Bone Morphogenetic Protein 2 Coordinates Early Tooth Mineralization. AMBN, Col1a1, DKK1, DSP, DSPP
54  2018 Conditional Deletion of Sost in MSC-Derived Lineages Identifies Specific Cell-Type Contributions to Bone Mass and B-Cell Development. BV/TV, HBM
55  2018 Do hypoxia and L-mimosine modulate sclerostin and dickkopf-1 production in human dental pulp-derived cells? Insights from monolayer, spheroid and tooth slice cultures. DKK1, DPC, L-MIM
56  2018 Estrogen Promotes Mandibular Condylar Fibrocartilage Chondrogenesis and Inhibits Degeneration via Estrogen Receptor Alpha in Female Mice. A2M, ERalpha, Pi15, TMJ-DD
57  2018 Improvement of bone defect healing in rats via mesenchymal stem cell supernatant. ALP, AMSC, BCA, BMP-2, BMSCs, CTX, MSCs, OCN, SD, TRACP, UMSC
58  2018 Osteocytic oxygen sensing controls bone mass through epigenetic regulation of sclerostin. PHD
59  2018 Paracrine and endocrine actions of bone-the functions of secretory proteins from osteoblasts, osteocytes, and osteoclasts. LCN2, OCN
60  2018 Parathyroid hormone(1-34) and its analogs differentially modulate osteoblastic Rankl expression via PKA/SIK2/SIK3 and PP1/PP2A-CRTC3 signaling. ABL, CREB, CRTC3, PKA, PTHR1, SIKs
61  2018 Sclerostin and Antisclerostin Antibody Serum Levels Predict the Presence of Axial Spondyloarthritis in Patients with Inflammatory Bowel Disease. anti-SOST-IgG, AS, IBD
62  2018 Sclerostin vaccination mitigates estrogen deficiency induction of bone mass loss and microstructure deterioration. ---
63  2018 Serum sclerostin and irisin as predictive markers for atherosclerosis in Egyptian type II diabetic female patients: A case control study. CVDs
64  2018 Serum Sclerostin Levels in Adults With Osteogenesis Imperfecta: Comparison With Normal Individuals and Response to Teriparatide Therapy. OI, vBMD
65  2018 SOST Gene Inhibits Osteogenesis from Adipose-Derived Mesenchymal Stem Cells by Inducing Th17 Cell Differentiation. ADSCs, Th17
66  2018 SOST, an LNGFR target, inhibits the osteogenic differentiation of rat ectomesenchymal stem cells. E12.5d, EMSCs, LNGFR
67  2018 SOST/Sclerostin Improves Posttraumatic Osteoarthritis and Inhibits MMP2/3 Expression After Injury. ACL, OA, PTOA, SOSTTG, WT
68  2018 The Lysosomal Protein Arylsulfatase B Is a Key Enzyme Involved in Skeletal Turnover. ARSB, CTSK, ERT, MPS VI
69  2018 The skeletal cell-derived molecule sclerostin drives bone marrow adipogenesis. BM, BMAT, MSC
70  2018 [TCP wear particles causes injury of periprosthetic osteocytes in the mouse calvaria]. 3-MA, BMD, BVF, DMP1, LC3, TCP, TCP
71  2017 Accelerated development of instability-induced osteoarthritis in transgenic mice overexpressing SOST. DMM, DXA, OA, Tg, WT
72  2017 Changes in expression of Wnt signaling pathway inhibitors dickkopf-1 and sclerostin before and after total joint arthroplasty. DKK1, OA, TJA
73  2017 Co-expression of DKK-1 and Sclerostin in Subchondral Bone of the Proximal Femoral Heads from Osteoarthritic Hips. OA
74  2017 Connecting Bone and Fat: The Potential Role for Sclerostin. MSCs
75  2017 Correlation of blood bone turnover biomarkers and Wnt signaling antagonists with AS, DISH, OPLL, and OYL. AS, DISH, DKK1, OPG, OPLL, OSC, OYL, SFRP1
76  2017 Differential involvement of Wnt signaling in Bmp regulation of cancellous versus periosteal bone growth. BMP
77  2017 Endothelin signaling regulates mineralization and posttranscriptionally regulates SOST in TMOb cells via miR 126-3p. DKK1, ECE-1, EDNRA, ET-1, IGF-1, TMOb
78  2017 Heterozygous deletion of both sclerostin (Sost) and connexin43 (Gja1) genes in mice is not sufficient to impair cortical bone modeling. Cx43
79  2017 Intermittent compressive stress regulates Notch target gene expression via transforming growth factor-beta signaling in murine pre-osteoblast cell line. TGF
80  2017 LRP5: From bedside to bench to bone. LRP5
81  2017 Multiple modes of Lrp4 function in modulation of Wnt/beta-catenin signaling during tooth development. ---
82  2017 Myostatin inhibits osteoblastic differentiation by suppressing osteocyte-derived exosomal microRNA-218: A novel mechanism in muscle-bone communication. miRNA
83  2017 Notch Signaling Participates in TGF-beta-Induced SOST Expression Under Intermittent Compressive Stress. hPDLs, TGF-beta
84  2017 PTH [1-34]-induced alterations predispose the mandibular condylar cartilage to mineralization. MCC, micro-CT
85  2017 Sequencing and bioinformatics analysis of the differentially expressed genes in herniated discs with or without calcification. CTSG, DEFA4, DEGs, GO, KEGG, PRTN3, RT-qPCR, WIF1
86  2017 Sost Deficiency does not Alter Bone's Lacunar or Vascular Porosity in Mice. KO, WT
87  2017 The Protective Effect of Chrysanthemum indicum Extract against Ankylosing Spondylitis in Mouse Models. AS, CAT, DKK1, GSH-Px, NF-kappaB, SOD
88  2017 The rs3736228 polymorphism in the LRP5 gene is associated with calcaneal ultrasound parameter but not with body composition in a cohort of young Caucasian adults. LRP5, QUS, SNPs
89  2017 Wnt Signaling Pathway Inhibitor Sclerostin Inhibits Angiotensin II-Induced Aortic Aneurysm and Atherosclerosis. AA
90  2017 Wnt-beta-catenin signaling pathway inhibition by sclerostin may protect against degradation in healthy but not osteoarthritic cartilage. OA
91  2016 Antagonizing miR-218-5p attenuates Wnt signaling and reduces metastatic bone disease of triple negative breast cancer cells. ---
92  2016 Critical roles of periostin in the process of orthodontic tooth movement. OTM, PDL, TRAP, WT
93  2016 Decreased Plasma Levels of Sclerostin But Not Dickkopf-1 are Associated with an Increased Prevalence of Osteoporotic Fracture and Lower Bone Mineral Density in Postmenopausal Korean Women. BMD, DKK1, OF
94  2016 Differential osteogenicity of multiple donor-derived human mesenchymal stem cells and osteoblasts in monolayer, scaffold-based 3D culture and in vivo. DMP1, hMSCs, OPG, PTHrP, RANKL, rhBMP-7
95  2016 Distinct Gene Expression Patterns Defining Human Osteoblasts' Response to BMP2 Treatment: Is the Therapeutic Success All a Matter of Timing? Alk6, BAMBI, BMPs, NOG, RANKL, RGMb
96  2016 Genetics of osteoporosis: searching for candidate genes for bone fragility. CTSK, GWAS
97  2016 Glucagon-like peptide-1(GLP-1) receptor agonists: potential to reduce fracture risk in diabetic patients? BMSCs, GLP-1, GLP-1RA, LRP, OPG, RANK, RANKL
98  2016 Idiopathic Acquired Osteosclerosis in a Middle-Aged Woman With Systemic Lupus Erythematosus. 25OHD, ALP, BMD, DKK1, DPA, DXA, eGFR, MMP-3, OCN, OPG, P1NP, PTH, RANKL, SLE
99  2016 Increased Dickkopf-1 in Recent-onset Rheumatoid Arthritis is a New Biomarker of Structural Severity. Data from the ESPOIR Cohort. DKK1, RA
100  2016 Lipoprotein receptor-related protein 6 is required for parathyroid hormone-induced Sost suppression. HDACs, LRP6, LRP6-KO, MEF2, PTH