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Abbreviation : SOX2
Long Form : SRY-box 2
No. Year Title Co-occurring Abbreviation
2020 Coagulation factor 2 thrombin receptor promotes malignancy in glioma under SOX2 regulation. EMT, F2R, GSEA
2020 Establishment and Characterization of a Stromal Cell Line Derived From a Patient With Thoracic Endometriosis. TE
2020 Newborn transient patterned hyperpigmentation and anophthalmia. ---
2020 SMARCA4/BRG1-Deficient Non-Small Cell Lung Carcinomas: A Case Series and Review of the Literature. ALK, BRG1, EGFR, Hep Par 1, NSCLCs, ROS1, SALL4, TTF-1
2020 Study of the protective effect on damaged intestinal epithelial cells of rat multilineage-differentiating stress-enduring (Muse) cells. BM-MSCs, Caco-2, IEC-6, IFN-gamma, IL-6, Muse, SSEA-1, SSEA-3, TGF-beta
2020 VDR-SOX2 signaling promotes colorectal cancer stemness and malignancy in an acidic microenvironment. ATAC-seq, ChIP, CRC, PPARD, VDR
2019 Betulinic acid inhibits stemness and EMT of pancreatic cancer cells via activation of AMPK signaling. AMPK, BA, CSCs, EMT, OCT4
2019 Biological analysis of flexor tendon repair-failure stump tissue: A potential recycling of tissue for tendon regeneration. IGF, MMPs, OCT4, PDGF, Scx, TDSCs, TNMD, VEGF
2019 Crosstalk between BMP and Notch Induces Sox2 in Cerebral Endothelial Cells. ALK, AVMs, BMP, EC
10  2019 Differential expression of claudin‑4, occludin, SOX2 and proliferating cell nuclear antigen between basaloid squamous cell carcinoma and squamous cell carcinoma. BSCCs, PCNA, SCC
11  2019 Effect of overexpression of Oct4 and Sox2 genes on the biological and oncological characteristics of gastric cancer cells. OCT4
12  2019 Effects of ten-eleven translocation 1 (Tet1) on DNA methylation and gene expression in chicken primordial germ cells. 5hmC, 5mC, Cav-1, DAZL, PGCs, Piwi1, Tet1
13  2019 Elevated endothelial Sox2 causes lumen disruption and cerebral arteriovenous malformations. AVMs, ECs, EndMTs, JMJD5
14  2019 Endometrial Cancer Stem Cells: Role, Characterization and Therapeutic Implications. ALDH, BMI1, EC, eCSC, NANOG, Wnt
15  2019 Establishment and Characterization of a Stromal Cell Line Derived From a Patient With Thoracic Endometriosis. TE
16  2019 Long Noncoding RNA LBCS Inhibits Self-Renewal and Chemoresistance of Bladder Cancer Stem Cells through Epigenetic Silencing of SOX2. BCSCs, EZH2, hnRNP K, lnc-LBCS
17  2019 Long noncoding RNAs sustain high expression levels of exogenous octamer-binding protein 4 by sponging regulatory microRNAs during cellular reprogramming. ceRNAs, circRNAs, iPSCs, KLF4, lincRNAs, lncRNAs, MEFs, miRNAs, OCT4
18  2019 MELK inhibition targets cancer stem cells through downregulation of SOX2 expression in head and neck cancer cells. CSCs, HNSCC, MELK, TFs
19  2019 Morphologic and histopathologic change of sodium iodate-induced retinal degeneration in adult rats. CRALBP, GS, PAX6, PCNA, RPE
20  2019 The Landscape of Actionable Molecular Alterations in Immunomarker-Defined Large-Cell Carcinoma of the Lung. ALK, FGFR1, LCC, PIK3CA, STK11
21  2018 beta-Catenin maintains lung epithelial progenitors after lung specification. FGF, GI, KRAS, NKX2-1, SOX9, TRAP
22  2018 LSD1 demethylase and the methyl-binding protein PHF20L1 prevent SET7 methyltransferase-dependent proteolysis of the stem-cell protein SOX2. Lys-119, PHF20L1
23  2018 The transcription factor NKX2-3 mediates p21 expression and ectodysplasin-A signaling in the enamel knot for cusp formation in tooth development. BMP, EDA
24  2018 Transcriptional repressor GATA binding 1-mediated repression of SRY-box 2 expression suppresses cancer stem cell functions and tumor initiation. CSCs, TRPS1
25  2018 Upregulation of stem cell markers ALDH1A1 and OCT4 as potential biomarkers for the early detection of cervical carcinoma. ALDH1A1, CIN, HPV, NANOG, PCR, RT-qPCR, SCC, Twist1
26  2017 Effect of SOX2 on odontoblast differentiation of dental pulp stem cells. DPSCs, DSPP
27  2017 Lineage tracing of epithelial cells in developing teeth reveals two strategies for building signaling centers. EK, IK
28  2017 Loss of SRY-box2 (SOX2) expression and its impact on survival of patients with oesophageal adenocarcinoma. HR, OAC
29  2016 Quantitative proteomics identify DAB2 as a cardiac developmental regulator that inhibits WNT/beta-catenin signaling. Cas9, CPCs, CRISPR, Dab2, DKK1, GATA4, hESCs, MYH6
30  2015 Inhibitor of DNA Binding 4 (ID4) is highly expressed in human melanoma tissues and may function to restrict normal differentiation of melanoma cells. CSCs, ID4
31  2014 Loss of miR-638 in vitro promotes cell invasion and a mesenchymal-like transition by influencing SOX2 expression in colorectal carcinoma cells. CRC, qRT-PCR
32  2011 Breast cancer cells produce tenascin C as a metastatic niche component to colonize the lungs. LGR5, MSI1, NANOG, STAT5, TN-C
33  2011 In vitro cardiomyogenic potential of human amniotic fluid stem cells. 5-AZA-dC, hAFS, NRCs, TPA
34  2010 Examination of SOX2 in variable ocular conditions identifies a recurrent deletion in microphthalmia and lack of mutations in other phenotypes. A/M
35  2010 Mutations in the LHX2 gene are not a frequent cause of micro/anophthalmia. GDF6, LHX2, OTX2, RAX