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Abbreviation : SQLE
Long Form : squalene epoxidase
No. Year Title Co-occurring Abbreviation
2019 A chemical biology screen identifies a vulnerability of neuroendocrine cancer cells to SQLE inhibition. ---
2019 Myclobutanil developmental toxicity, bioconcentration and sex specific response in cholesterol in zebrafish (Denio rerio). BCF, DHCR24, DHCR7, FDFT1, HMGCRa, hph, IDI1, MYC
2019 Non-nucleoside reverse transcriptase inhibitor efavirenz activates PXR to induce hypercholesterolemia and hepatic steatosis. PXR
2019 OSBPL2 deficiency upregulate SQLE expression increasing intracellular cholesterol and cholesteryl ester by AMPK/SP1 and SREBF2 signalling pathway. OSBPL2, SP1, SREBF2
2019 Squalene epoxidase promotes the proliferation and metastasis of lung squamous cell carcinoma cells though extracellular signal-regulated kinase signaling. ERK, SCC
2019 Structure and inhibition mechanism of the catalytic domain of human squalene epoxidase. ---
2019 Terbinafine-resistant strain of Trichophyton interdigitale strain isolated from a tinea pedis patient. ITZ, MIC, TRF
2019 The shape of human squalene epoxidase expands the arsenal against cancer. ---
2019 [Extensive tinea corporis due to aterbinafine-resistant Trichophyton mentagrophytes isolate of the Indian genotype in ayoung infant from Bahrain in Germany]. ITS
10  2018 Correlation of In Vitro Susceptibility Based on MICs and Squalene Epoxidase Mutations with Clinical Response to Terbinafine in Patients with Tinea Corporis/Cruris. ITR, ITS, OD, TRB
11  2018 High terbinafine resistance in Trichophyton interdigitale isolates in Delhi, India harbouring mutations in the squalene epoxidase gene. ---
12  2018 Phenolic Compounds from Belamcanda chinensis Seeds. GC, HMGCR, LDLR
13  2018 RNA Sequencing-Based Whole-Transcriptome Analysis of Friesian Cattle Fed with Grape Pomace-Supplemented Diet. FDFT-1, GPO, LDLR, MSMO, NSDHL, SC5D
14  2018 Squalene epoxidase drives NAFLD-induced hepatocellular carcinoma and is a pharmaceutical target. DNMT3A, HCC, NAFLD
15  2018 The cancer-associated microprotein CASIMO1 controls cell proliferation and interacts with squalene epoxidase modulating lipid droplet formation. CASIMO1, lncRNAs, sORF
16  2017 SQLE induces epithelial-to-mesenchymal transition by regulating of miR-133b in esophageal squamous cell carcinoma. EMT, ESCC
17  2017 Squalene epoxidase plays a critical role in determining pig meat quality by regulating adipogenesis, myogenesis, and ROS scavengers. SNPs
18  2017 Terbinafine Resistance of Trichophyton Clinical Isolates Caused by Specific Point Mutations in the Squalene Epoxidase Gene. ---
19  2016 A MARCH6 and IDOL E3 Ubiquitin Ligase Circuit Uncouples Cholesterol Synthesis from Lipoprotein Uptake in Hepatocytes. HMGCR, LDLR, SREBP
20  2015 Squalene epoxidase (SQLE) promotes the growth and migration of the hepatocellular carcinoma cells. HCC
21  2014 Dexamethasone acutely down-regulates genes involved in steroidogenesis in stallion testes. ACTN4, DHCR24, GSTA3, LHCGR, NFKBIA
22  2014 Exposure to high levels of glucose increases the expression levels of genes involved in cholesterol biosynthesis in rat islets. DHCR7, Idi1
23  2014 Expression and significance of squalene epoxidase in squamous lung cancerous tissues and pericarcinoma tissues. ---
24  2013 Ductal carcinoma of the prostate shows a different immunophenotype from high grade acinar cancer. AC, AR, DC, ERA and ERB
25  2012 Roles of 7-ketocholesterol on the homeostasis of intracellular cholesterol level. ---
26  2011 Potential role of nonstatin cholesterol lowering agents. HMGR, OSC
27  2010 Congenic and bioinformatics analyses resolved a major-effect Fob3b QTL on mouse Chr 15 into two closely linked loci. ADI, QTL
28  2006 Changes in hepatic gene expression associated with the hypocholesterolaemic activity of royal jelly. LDLR, RJ, SREB
29  2005 Microarray gene expression analysis of the Fob3b obesity QTL identifies positional candidate gene Sqle and perturbed cholesterol and glycolysis pathways. QTL
30  2004 Hepatic gene expression profiles in a long-term high-fat diet-induced obesity mouse model. ACOX1, Acs2, FASN, GSTs, HFD, HSPs, LFD
31  2002 Chromosomal localization of genes involved in biosynthesis, metabolism or transport of cholesterol in the rat. Abca7, Fdft1, LCAT, MVK, PLTP, RH, SCP-2, StAR