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Abbreviation : STAT5
Long Form : signal transducer and activator of transcription 5
No. Year Title Co-occurring Abbreviation
2020 A Mixture of Humulus japonicus Increases Longitudinal Bone Growth Rate in Sprague Dawley Rats. BrdU, IGF-I, IGFBP-3, JAK2, MH, SD
2020 Acute Plasmodium berghei Mouse Infection Elicits Perturbed Erythropoiesis With Features That Overlap With Anemia of Chronic Disease. EPO
2020 Aurora kinase inhibitor restrains STAT5-activated leukemic cell proliferation by inducing mitochondrial impairment. AML, ATP, cS5, ROS
2020 c-FLIP is crucial for IL-7/IL-15-dependent NKp46+ ILC development and protection from intestinal inflammation in mice. c-FLIP, cNK, IL, ILC
2020 Emodin Inhibits Resistance to Imatinib by Downregulation of Bcr-Abl and STAT5 and Allosteric Inhibition in Chronic Myeloid Leukemia Cells. Bcr-Abl, CML, PARP
2020 Endoplasmic reticulum stress induces growth retardation by inhibiting growth hormone IGF-I axis. ELISA, ER, GH, JAK2, TM
2020 Erythropoietin induces miRNA-210 by JAK2/STAT5 signaling in PBMCs of End-stage Renal Disease patients. EPO, ERI, ESAs, HC, HD, JAK2
2020 Hoxd10 Is Required Systemically for Secretory Activation in Lactation and Interacts Genetically with Hoxd9. GLUT1
2020 IGHG1 functions as an oncogene in tongue squamous cell carcinoma via JAK1/STAT5 signaling. CCK-8, IGHG1, IHC, JAK1, RT-PCR, TSCC
10  2020 Interleukin 9 prevents immune thrombocytopenia in mice via JAK/STAT5 signaling. IL-9, IL-9R, ITP, siRNA
11  2020 Leprosy drug clofazimine activates peroxisome proliferator-activated receptor-gamma and synergizes with imatinib to inhibit chronic myeloid leukemia cells. CITED2, CML, PPARgamma
12  2020 Molecular identification, tissue distribution and in vitro functional analysis of growth hormone and its receptors in red-spotted grouper (Epinephelus akaara). GH, rgGH
13  2020 Phospho-PTM proteomic discovery of novel EPO- modulated kinases and phosphatases, including PTPN18 as a positive regulator of EPOR/JAK2 Signaling. AAK1, AKT, CKD, EPO, GUK1, JAK2, MDS, MPP1, p-Y PTM, PEAK1, PHPT1, PTPN18, PTPRA, rhEPO, UBASH3B
14  2020 Prolactin receptor-mediated activation of pSTAT5 in the pregnant mouse brain. PRLR, pSTAT5
15  2020 Regulation and neurochemical identity of melanin-concentrating hormone neurones in the preoptic area of lactating mice. MCH, MPOA
16  2020 Regulatory Effects of Soy Isoflavones and Their Metabolites in Milk Production via Different Ways in Mice. MECs
17  2020 RelB regulates the homeostatic proliferation but not the function of Tregs. ---
18  2020 SHIP-1 Regulates Phagocytosis and M2 Polarization Through the PI3K/Akt-STAT5-Trib1 Circuit in Pseudomonas aeruginosa Infection. PI3K, WT
19  2020 STAT5 is Expressed in CD34+/CD38- Stem Cells and Serves as a Potential Molecular Target in Ph-Negative Myeloproliferative Neoplasms. JAK2, MPN, MPN-SC
20  2020 STAT5: From Pathogenesis Mechanism to Therapeutic Approach in Acute Leukemia. Bcl-2, hTERT
21  2020 Structure-Activity Relationship Analysis of Benzotriazine Analogues as HIV-1 Latency-Reversing Agents. LRA
22  2020 The anti-CXCL4 antibody depletes CD4(+)CD25(+)FOXP3(+) regulatory T cells in CD4+ T cells from chronic osteomyelitis patients by the STAT5 pathway. CTLA-4, FOXP3
23  2019 A benzoxazole derivative PO-296 inhibits T lymphocyte proliferation by the JAK3/STAT5 signal pathway. CD, IL, JAK3, PI3K
24  2019 Acute effects of somatomammotropin hormones on neuronal components of the hypothalamic-pituitary-gonadal axis. GH, HPG, PRL
25  2019 Anti-IL-7 receptor alpha monoclonal antibody (GSK2618960) in healthy subjects - a randomized, double-blind, placebo-controlled study. ADAs, IL
26  2019 Brain STAT5 Modulates Long-Term Metabolic and Epigenetic Changes Induced by Pregnancy and Lactation in Female Mice. KO
27  2019 CircScd1 Promotes Fatty Liver Disease via the Janus Kinase 2/Signal Transducer and Activator of Transcription 5 Pathway. circRNAs, JAK2, NAFLD
28  2019 Decreased expression of STAT5A predicts poor prognosis in osteosarcoma. EFS, GSEA, OS
29  2019 Fatherhood diminishes the hippocampal damaging action of excitotoxic lesioning in mice. PRL
30  2019 Ginkgetin, a biflavone from Ginkgo biloba leaves, prevents adipogenesis through STAT5-mediated PPARgamma and C/EBPalpha regulation. PPARgamma
31  2019 Growth hormone enhances the recovery of hypoglycemia via ventromedial hypothalamic neurons. 2-DG, CRR, GH, GHR, LEPR, SF-1
32  2019 IL-17 constrains natural killer cell activity by restraining IL-15-driven cell maturation via SOCS3. NK, WT
33  2019 Increased expression of thymic stromal lymphopoietin receptor in a rat model of middle cerebral artery occlusion. IL-7, TSLP, TSLPR
34  2019 Isoliquiritigenin, an Orally Available Natural FLT3 Inhibitor from Licorice, Exhibits Selective Anti-Acute Myeloid Leukemia Efficacy In Vitro and In Vivo. FLT3, FLT3-ITD, ISL
35  2019 Loss of growth hormone-mediated signal transducer and activator of transcription 5 (STAT5) signaling in mice results in insulin sensitivity with obesity. GH, GHR, PCK, STAT
36  2019 Lymphocyte Activation Gene-3 Maintains Mitochondrial and Metabolic Quiescence in Naive CD4+ T Cells. IL-7, LAG-3
37  2019 Mannan-Binding Lectin Regulates Inflammatory Cytokine Production, Proliferation, and Cytotoxicity of Human Peripheral Natural Killer Cells. CLR, IFN-gamma, ILC, LAK, NK, TNF-alpha
38  2019 NPM1c alters FLT3-D835Y localization and signaling in acute myeloid leukemia. AML, FLT3, NPM1, TKD
39  2019 PP2A enables IL-2 signaling by preserving IL-2Rbeta chain expression during Treg development. ADAM10, PP2A
40  2019 Seasonal expressions of prolactin, prolactin receptor and STAT5 in the scented glands of the male muskrats (Ondatra zibethicus). ELISA, PRL, PRLR, pSTAT5
41  2019 Siglec-F is induced by granulocyte-macrophage colony-stimulating factor and enhances interleukin-4-induced expression of arginase-1 in mouse macrophages. GM-CSF
42  2019 Temporal patterns of lipolytic regulators in adipose tissue after acute growth hormone exposure in human subjects: A randomized controlled crossover trial. AT, CISH, FSP27, G0S2, GH, PTEN
43  2019 The inhibitor of interleukin-3 receptor protects against sepsis in a rat model of cecal ligation and puncture. CLP, IL-10, IL-1beta, IL-3, IL-6, JAK2, MAP, TNF-alpha
44  2018 Are the Effects of the Cholera Toxin and Isoproterenol on Human Keratinocytes' Proliferative Potential Dependent on Whether They Are Co-Cultured with Human or Murine Fibroblast Feeder Layers? AMPKalpha1, cAMP, CT, iFL, ISO
45  2018 ATM Is Required for the Prolactin-Induced HSP90-Mediated Increase in Cellular Viability and Clonogenic Growth After DNA Damage. ATM, Hsp90, JAK2, PRL
46  2018 Brain STAT5 signaling modulates learning and memory formation. IGF-1, STAT5 KO
47  2018 Carcinoembryonic antigen-related cell adhesion molecule 1 controls IL-2-dependent regulatory T-cell induction in immune-mediated hepatitis in mice. IL
48  2018 Deregulation of kinase signaling and lymphoid development in EBF1-PDGFRB ALL leukemogenesis. B-ALL, EBF1-PDGFRB, IL-7, TM
49  2018 Dipeptide (Methionyl-Methionine) Transport and Its Effect on beta-Casein Synthesis in Bovine Mammary Epithelial Cells. beta-CN, BMECs, JAK2, Met-Met, mTOR, PEPT2
50  2018 Excreted-secreted antigens of Toxoplasma gondii inhibit Foxp3 via IL-2Rgamma/JAK3/Stats pathway. ESA, FOXP3, IL-2, IL-2Rgamma, JAK3
51  2018 GSK3-activated STAT5 regulates expression of SFRPs to modulate adipogenesis. SFRPs
52  2018 Hepatitis C virus core protein reduces CD8+ T-cell proliferation, perforin production and degranulation but increases STAT5 activation. HCV
53  2018 Identification of an Essential Cytoplasmic Region of Interleukin-7 Receptor alpha Subunit in B-Cell Development. HPCs, IL-7, IL-7R, tSTAT5, WT
54  2018 In silico mapping of quantitative trait loci (QTL) regulating the milk ionome in mice identifies a milk iron locus on chromosome 1. Ca, GWAS, MDP, Mmcq, QTL, SLC, Zn
55  2018 Integrative view on how erythropoietin signaling controls transcription patterns in erythroid cells. EPO
56  2018 Lysine Stimulates Protein Synthesis by Promoting the Expression of ATB0,+ and Activating the mTOR Pathway in Bovine Mammary Epithelial Cells. BMECs, JAK2, Lys, mTOR
57  2018 Moderate High Temperature Condition Induces the Lactation Capacity of Mammary Epithelial Cells Through Control of STAT3 and STAT5 Signaling. GR, MECs, TJs
58  2018 No erythropoietin-induced growth is observed in non-small cell lung cancer cells. EPO, JAK2, MAP, NSCLC, PI3K
59  2018 p-Cresyl sulfate decreases peripheral B cells in mice with adenine-induced renal dysfunction. CKD, IL, PCS
60  2018 Persistent STAT5-mediated ROS production and involvement of aberrant p53 apoptotic signaling in the resistance of chronic myeloid leukemia to imatinib. ABL1, Bax, Bcl-2, bcr, CML, MDM2, ROS
61  2018 RANKL-mediated osteoclastogenic differentiation of macrophages in the abdominal aorta of angiotensin II-infused apolipoprotein E knockout mice. AAAs, Ang II, JAK2, MOVAS, OCG, RANKL
62  2018 Selective Effects of mTOR Inhibitor Sirolimus on Naive and CMV-Specific T Cells Extending Its Applicable Range Beyond Immunosuppression. aAPCs, CMV, GzB, IFN-gamma, IL-2R, mTOR, NGS, TCR
63  2018 The Cooperative Relationship between STAT5 and Reactive Oxygen Species in Leukemia: Mechanism and Therapeutic Potential. ABL, FLT3, JAKs, ROS, SFKs
64  2018 The immunobiology of mucosal-associated invariant T cell (MAIT) function in primary biliary cholangitis: Regulation by cholic acid-induced Interleukin-7. FXR, HC, MAIT, PBC
65  2018 The Role of Signal Transducer and Activator of Transcription 5 and Transforming Growth Factor-beta1 in Hepatic Fibrosis Induced by Chronic Hepatitis C Virus Infection in Egyptian Patients. alpha-SMA, CHC, HOMA-IR, HSC
66  2018 Toll-interacting protein differentially modulates HIF1alpha and STAT5-mediated genes in fibroblasts. CUE, FABP4, HIF-1alpha, IL-6, TNF-alpha
67  2018 [Effect of interleukin-7 on the anti-tumor function of CD8(+) T cells in patients with non-small cell lung cancer]. BALF, IFN, IL, NSCLC, PBMCs, SOCS3, TNF
68  2017 Assessing HDAC Function in the Regulation of Signal Transducer and Activator of Transcription 5 (STAT5) Activity Using Chromatin Immunoprecipitation (ChIP). ChIP
69  2017 Blockade of Y177 and Nuclear Translocation of Bcr-Abl Inhibits Proliferation and Promotes Apoptosis in Chronic Myeloid Leukemia Cells. CML, MAPK, TKI
70  2017 Calreticulin mutant mice develop essential thrombocythemia that is ameliorated by the JAK inhibitor ruxolitinib. BM, CALR, ET, HSCs, JAK, WT
71  2017 Decreased frequencies and impaired functions of the CD31+ subpopulation in Treg cells associated with decreased FoxP3 expression and enhanced Treg cell defects in patients with coronary heart disease. CD31- Tr cells, CHD, IL, TGF, Treg
72  2017 Deletion of liver-specific STAT5 gene alters the expression of bile acid metabolism genes and reduces liver damage in lithogenic diet-fed mice. ---
73  2017 Development of protein degradation inducers of oncogenic BCR-ABL protein by conjugation of ABL kinase inhibitors and IAP ligands. ABL, cIAP1, CML, CrkL, IAP, PEG, XIAP
74  2017 Elderly-onset hereditary pulmonary alveolar proteinosis and its cytokine profile. CSF2RA, GM-CSF, IL, PAP, WLL
75  2017 Hepatocyte-Specific Deletion of Mouse Lamin A/C Leads to Male-Selective Steatohepatitis. ERK, JAK2, KO, STAT1
76  2017 Histone H1 and Chromosomal Protein HMGN2 Regulate Prolactin-induced STAT5 Transcription Factor Recruitment and Function in Breast Cancer Cells. HMGN2, PRL
77  2017 IL-7-dependent STAT1 activation limits homeostatic CD4+ T cell expansion. ISGs, LIP
78  2017 Imipramine blue sensitively and selectively targets FLT3-ITD positive acute myeloid leukemia cells. AML, ER, IB, NOX, RTKs, TG
79  2017 Interleukin-7 Induces Osteoclast Formation via STAT5, Independent of Receptor Activator of NF-kappaB Ligand. IL-7, IL-7Ralpha, RANKL
80  2017 Intestinal immune responses of Jian carp against Aeromonas hydrophila depressed by choline deficiency: Varied change patterns of mRNA levels of cytokines, tight junction proteins and related signaling molecules among three intestinal segments. IFN-gamma2b, IkappaB, IL, JAK3, LEAP, MyD88, NF-kappaB, TGF-beta2, TLR4, TNF-alpha
81  2017 Isoflavones and their metabolites influence the milk component synthesis ability of mammary epithelial cells through prolactin/STAT5 signaling. MECs
82  2017 Low-dose interleukin-2 promotes STAT-5 phosphorylation, Treg survival and CTLA-4-dependent function in autoimmune liver diseases. CTLA-4, IL, VLDP
83  2017 M-COPA suppresses endolysosomal Kit-Akt oncogenic signalling through inhibiting the secretory pathway in neoplastic mast cells. ER, GISTs, PI3K-Akt, PM
84  2017 MiR-139 suppresses beta-casein synthesis and proliferation in bovine mammary epithelial cells by targeting the GHR and IGF1R signaling pathways. BMECs, GHR, mTOR, p70S6K, UTR
85  2017 Muscle-specific deletion of signal transducer and activator of transcription 5 augments lipid accumulation in skeletal muscle and liver of mice in response to high-fat diet. GH, HFD, IMCL
86  2017 New Inhibitor Targeting Signal Transducer and Activator of Transcription 5 (STAT5) Signaling in Myeloid Leukemias. STAT5s
87  2017 O-GlcNAcylation of STAT5 controls tyrosine phosphorylation and oncogenic transcription in STAT5-dependent malignancies. GOF
88  2017 Oncogenic signaling by Kit tyrosine kinase occurs selectively on the Golgi apparatus in gastrointestinal stromal tumors. GISTs, PI3K-Akt, PM
89  2017 Phosphorylated CIS suppresses the Epo or JAK2 V617F mutant-triggered cell proliferation through binding to EpoR. MPNs, SOCS
90  2017 Phosphorylated STAT5 directly facilitates parvovirus B19 DNA replication in human erythroid progenitors through interaction with the MCM complex. BFU-E, CFU-E, MCM
91  2017 Reduced PRF1 enhancer methylation in children with a history of severe RSV bronchiolitis in infancy: an association study. CI, CpG, RSV
92  2017 Stat5 deficiency decreases transcriptional heterogeneity and supports emergence of hematopoietic sub-populations. KLS, LT-HSC, PCR
93  2017 Targeting androgen receptor with ASC-J9 attenuates cardiac injury and dysfunction in experimental autoimmune myocarditis by reducing M1-like macrophage. AR, EAM, SOCS1
94  2017 Thermal injury of the skin induces G-CSF-dependent attenuation of EPO-mediated STAT signaling and erythroid differentiation arrest in mice. ACI, EPO, EPO, G-CSF
95  2017 Thymus-Derived Regulatory T Cell Development Is Regulated by C-Type Lectin-Mediated BIC/MicroRNA 155 Expression. miR-155, shRNA, SOCS-1, tTreg
96  2017 Versican G1 domain enhances adenoviral-mediated transgene expression and can be modulated by inhibitors of the Janus kinase (JAK)/STAT and Src family kinase pathways. JAK
97  2016 A Multifaceted Role for Myd88-Dependent Signaling in Progression of Murine Mammary Carcinoma. ERK, MYD88, NF-kappaB, TLR
98  2016 An invertebrate signal transducer and activator of transcription 5 (STAT5) ortholog from the disk abalone, Haliotis discus discus: Genomic structure, early developmental expression, and immune responses to bacterial and viral stresses. JAK, SH2, STAT
99  2016 Brain STAT5 signaling and behavioral control. ---
100  2016 CSF2 Overexpression Is Associated with STAT5 Phosphorylation and Poor Prognosis in Patients with Urothelial Carcinoma. CSF2, DSS, MeFS, UB, UC, UT