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Abbreviation : STIM1
Long Form : stromal interaction molecule 1
No. Year Title Co-occurring Abbreviation
2020 A novel frame shift mutation in STIM1 gene causing primary immunodeficiency. ---
2020 BIN2 orchestrates platelet calcium signaling in thrombosis and thrombo-inflammation. BIN2, SOCE
2020 Ca2+ release-activated Ca2+ channels are responsible for histamine-induced Ca2+ entry, permeability increase, and interleukin synthesis in lymphatic endothelial cells. HDLECs, LECs
2020 Calcium entry units (CEUs): perspectives in skeletal muscle function and disease. CEUs, ER and SR, PM, TAM, TAs, TTs
2020 Calcium Sets the Clock in Ameloblasts. AI, Bmal1, Per2, TGF-beta1
2020 Circular RNA circHIPK3 modulates the proliferation of airway smooth muscle cells by miR-326/STIM1 axis. ASMCs, circRNA, ncRNA, PDGF
2020 Clinical and muscle MRI features in a family with tubular aggregate myopathy and novel STIM1 mutation. ---
2020 Defective interaction of mutant calreticulin and SOCE in megakaryocytes from patients with myeloproliferative neoplasms. CALR, ER, ERp57, MKs, MPNs
2020 Hsa_circ_0029589 knockdown inhibits the proliferation, migration and invasion of vascular smooth muscle cells via regulating miR-214-3p and STIM1. circRNAs, miR-214-3p, oxLDL, VSMCs
10  2020 Insights into Activation Mechanisms of Store-Operated TRPC1 Channels in Vascular Smooth Muscle. CRACs, MARCKS, PKC, SOCs, TRPC, VMSCs
11  2020 Luminal STIM1 Mutants that Cause Tubular Aggregate Myopathy Promote Autophagic Processes. MD, MITF, TFEB
12  2020 Molecular Basis and Regulation of Store-Operated Calcium Entry. ---
13  2020 Molecular basis of allosteric Orai1 channel activation by STIM1. ---
14  2020 Neuroprotective Effects of Dexmedetomidine Preconditioning on Oxygen-glucose Deprivation-reoxygenation Injury in PC12 Cells via Regulation of Ca2+-STIM1/Orai1 Signaling. alpha2-AR, DEX, LC3, OGD/R
15  2020 Nitric Oxide Critically Regulates Purkinje Neuron Dendritic Development Through a Metabotropic Glutamate Receptor Type 1-Mediated Mechanism. mGluR1, nNOS, NO, PD7, PNs, WT
16  2020 Optogenetic engineering to probe the molecular choreography of STIM1-mediated cell signaling. ---
17  2020 Pathophysiological significance of Stim1 mutation in sympathetic response to stress and cardiovascular phenotypes in SHRSP/Izm: In vivo evaluation by creation of a novel gene knock-in rat using CRISPR/Cas9. BP
18  2020 Peptidylarginine Deiminase Isozyme-Specific PAD2, PAD3 and PAD4 Inhibitors Differentially Modulate Extracellular Vesicle Signatures and Cell Invasion in Two Glioblastoma Multiforme Cell Lines. EV, GBM, KEGG, PADs, PHB
19  2020 Plasma Long Non-Coding RNA RP11-438N5.3 as a Novel Biomarker for Non-Small Cell Lung Cancer. AUC, HCs, lncRNAs, NSCLC, qRT-PCR, ROC
20  2020 Potential Role of PDGFRbeta-Associated THBS4 in Colorectal Cancer Development. PDGFRbeta, TGF-beta, THBS4
21  2020 Predictive value of serum CTRP9 and STIM1 for restenosis after cerebrovascular stent implantation and its relationship with vasoactive substances and inflammatory cytokines. CTRP9, ELISA, IL-6, NO, TNF-alpha
22  2020 Prostaglandin E2 receptor EP4 regulates cell migration through Orai1. PGE2
23  2020 Single nucleotide polymorphisms in the non-coding region of STIM1 gene are associated with Parkinson disease risk in Chinese Han population. ELISA, PD, SNP
24  2020 STIM calcium sensing and conformational change. ER, PM
25  2020 STIM1 controls calcineurin/Akt/mTOR/NFATC2-mediated osteoclastogenesis induced by RANKL/M-CSF. BMDM, CID, M-CSF, mTOR, NFATC2, RANKL
26  2020 STIM1 interacts with termini of Orai channels in a sequential manner. ---
27  2020 STIM1 is a metabolic checkpoint regulating the invasion and metastasis of hepatocellular carcinoma. FAO, HCC
28  2020 STIM1 R304W in mice causes subgingival hair growth and an increased fraction of trabecular bone. CRAC, GOF, SOCE
29  2020 STIM1-Ca2+ signaling in coronary sinus cardiomyocytes contributes to interatrial conduction. CSC, SAN
30  2020 STIM1-mediated calcium influx controls antifungal immunity and the metabolic function of non-pathogenic Th17 cells. OXPHOS
31  2020 Stromal interaction molecule 1 promotes tumor growth in Esophageal squamous cell carcinoma. ESCC
32  2020 The coordinated outcome of STIM1-Orai1 and superoxide signalling is crucial for headkidney macrophage apoptosis and clearance of Mycobacterium fortuitum. HKM
33  2020 The short isoform of extended synaptotagmin-2 controls Ca2+ dynamics in T cells via interaction with STIM1. E-Syt, ER, PM
34  2020 TRIC-A shapes oscillatory Ca2+ signals by interaction with STIM1/Orai1 complexes. ER, PM, RyR2, TRIC
35  2020 TRPP2 and STIM1 form a microdomain to regulate store-operated Ca2+ entry and blood vessel tone. 2-APB, ATP, cKO, siRNA, TG, VSMCs
36  2020 Wenyang Huazhuo Fang exerts transient receptor potential cation channel subfamily C member-dependent nephroprotection in a rat model of doxorubicin-induced nephropathy. TRPC6, WHF
37  2019 A muscular hypotonia-associated STIM1 mutant at R429 induces abnormalities in intracellular Ca2+ movement and extracellular Ca2+ entry in skeletal muscle. TEM
38  2019 Adenylyl Cyclase Type 8 Overexpression Impairs Phosphorylation-Dependent Orai1 Inactivation and Promotes Migration in MDA-MB-231 Breast Cancer Cells. AC8, cAMP, FAK, OASF, PKA, PKC, siRNAs, TG, TNBC
39  2019 Atorvastatin ameliorates the contractile dysfunction of the aorta induced by organ culture. alpha-SMA, PKCdelta, VSMCs
40  2019 Ca2+ Influx Channel Inhibitor SARAF Protects Mice From Acute Pancreatitis. SARAF
41  2019 Calcium Imaging of Store-Operated Calcium (Ca2+) Entry (SOCE) in HEK293 Cells Using Fura-2. HEK, PM
42  2019 Calcium Signaling Controls Pathogenic Th17 Cell-Mediated Inflammation by Regulating Mitochondrial Function. ROS, STAT3, TCR
43  2019 Cardiomyocyte-Specific STIM1 (Stromal Interaction Molecule 1) Depletion in the Adult Heart Promotes the Development of Arrhythmogenic Discordant Alternans. AP, APD, STIM1-KD, VT/VF
44  2019 CRAC channels and disease - From human CRAC channelopathies and animal models to novel drugs. GOF, LOF, TAM
45  2019 Cross-talk between N-terminal and C-terminal domains in stromal interaction molecule 2 (STIM2) determines enhanced STIM2 sensitivity. 2-APB, ER, PM, STIM2
46  2019 Detecting In-Situ oligomerization of engineered STIM1 proteins by diffraction-limited optical imaging. EGFP, ehSTIM1, ER, PM
47  2019 Does stromal interaction molecule-1 have five senses? ER
48  2019 Functional consequences of enhanced expression of STIM1 and Orai1 in Huh-7 hepatocellular carcinoma tumor-initiating cells. EpCAM, ER, HCC, PM
49  2019 Generation of Amelx-iCre Mice Supports Ameloblast-Specific Role for Stim1. iCre, Stim1 cKO
50  2019 Inhibition of MCF-7 breast cancer cell proliferation by a synthetic peptide derived from the C-terminal sequence of Orai channel. ---
51  2019 Knockdown of STIM1 expression inhibits non-small-cell lung cancer cell proliferation in vitro and in nude mouse xenografts. CDK, NSCLC
52  2019 Mechanistic insights into store-operated Ca2+ entry during excitation-contraction coupling in skeletal muscle. E-C, RyR1, SR
53  2019 Mibefradil, a T-type Ca2+ channel blocker also blocks Orai channels by action at the extracellular surface. ---
54  2019 miRNA-185 regulates retained fetal membranes of cattle bytargetingSTIM1. qPCR, RFM, UCE, WB
55  2019 MURC/CAVIN-4 facilitates store-operated calcium entry in neonatal cardiomyocytes. MURC, NRVM, SOCE
56  2019 Novel role of the ER/SR Ca2+ sensor STIM1 in the regulation of cardiac metabolism. ---
57  2019 Peripheral myelin protein 22 modulates store-operated calcium channel activity, providing insights into Charcot-Marie-Tooth disease etiology. CMT, ER, PMP22, SOC, TrpC1
58  2019 Phosphoproteomics reveals conserved exercise-stimulated signaling and AMPK regulation of store-operated calcium entry. ---
59  2019 Receptor- and store-operated mechanisms of calcium entry during the nanosecond electric pulse-induced cellular response. Pr, ROCE/SOCE, TRPC, YP1
60  2019 Remodeling of ER-plasma membrane contact sites but not STIM1 phosphorylation inhibits Ca2+ influx in mitosis. CSs, ER, PM
61  2019 Resveratrol pretreatment alleviates myocardial ischemia/reperfusion injury by inhibiting STIM1-mediated intracellular calcium accumulation. I/R, NRVCs
62  2019 Role of calcium in adult onset polycystic kidney disease. AC, ADPKD, PC, PN
63  2019 Sequential activation of STIM1 links Ca2+ with luminal domain unfolding. MD
64  2019 STIM1 at the plasma membrane as a new target in progressive chronic lymphocytic leukemia. BCR, CLL, STIM1PM, TRPC
65  2019 STIM1 expression is associated with osteosarcoma cell survival. NFATc1, SOCE
66  2019 STIM1 Is Required for Remodeling of the Endoplasmic Reticulum and Microtubule Cytoskeleton in Steering Growth Cones. ER
67  2019 STIM1 overexpression in hypoxia microenvironment contributes to pancreatic carcinoma progression. PDAC, TMA
68  2019 STIM1 phosphorylation at Y316 modulates its interaction with SARAF and the activation of SOCE and I CRAC. WT
69  2019 Store-Operated Calcium Entry Contributes to Cisplatin-Induced Cell Death in Non-Small Cell Lung Carcinoma. DDR, NSCLC, ROS, SOCE, TRPC1
70  2019 Store-operated calcium entry in disease: Beyond STIM/Orai expression levels. SOCE
71  2019 Store-Operated Calcium Entry via STIM1 Contributes to MRGPRX2 Induced Mast Cell Functions. GPCR, MRGPRX2
72  2019 Stormorken Syndrome: A Rare Cause of Myopathy With Tubular Aggregates and Dystrophic Features. ---
73  2019 Synaptic crosstalk conferred by a zone of differentially regulated Ca2+ signaling in the dendritic shaft adjoining a potentiated spine. beta-ARs, ER
74  2019 The Ca2+ export pump PMCA clears near-membrane Ca2+ to facilitate store-operated Ca2+ entry and NFAT activation. NFAT, PMCA4
75  2019 The Ca2+ sensor STIM1 regulates the type I interferon response by retaining the signaling adaptor STING at the endoplasmic reticulum. ER, STING
76  2019 The deregulation of STIM1 and store operative calcium entry impaired aortic smooth muscle cells contractility in aortic medial degeneration. alpha-SMA, AMD, Ang II, ASMCs, ATF6, ER, EVG, IF, IHC, MLC, PI, TGF
77  2019 The Orai Ca2+ channel inhibitor CM4620 targets both parenchymal and immune cells to reduce inflammation in experimental acute pancreatitis. ER, PaSCs, PBMCs
78  2019 The steroid hormone 20-hydroxyecdysone induces phosphorylation and aggregation of stromal interacting molecule 1 for store-operated calcium entry. EcRE, GPCRs, PKC, PLC, RNAi, SOCE
79  2019 TRPP2 associates with STIM1 to regulate cerebral vasoconstriction and enhance high salt intake-induced hypertensive cerebrovascular spasm. SOCE, TTC
80  2019 Very Low-Density Lipoproteins of Metabolic Syndrome Modulates STIM1, Suppresses Store-Operated Calcium Entry, and Deranges Myofilament Proteins in Atrial Myocytes. MetS, NFAT, SR, VLDLs
81  2018 A case-control study between the STIM1 gene and hypertensive disorders of pregnancy. HDP, SNPs
82  2018 A charge-sensing region in the stromal interaction molecule 1 luminal domain confers stabilization-mediated inhibition of SOCE in response to S-nitrosylation. EFSAM, ER/SR
83  2018 A mechanically activated TRPC1-like current in white adipocytes. TRP
84  2018 Authentic CRAC channel activity requires STIM1 and the conserved portion of the Orai N terminus. ---
85  2018 Calcium Independent Effect of Orai1 and STIM1 in Non-Hodgkin B Cell Lymphoma Dissemination. DLBCL, SDF-1
86  2018 Calcium oscillations in fertilized pig oocytes are associated with repetitive interactions between STIM1 and ORAI1. CPA, FRET
87  2018 Calcium sensing by the STIM1 ER-luminal domain. ---
88  2018 CaMKII Potentiates Store-Operated Ca2+ Entry Through Enhancing STIM1 Aggregation and Interaction with Orai1. CaMKII, TG
89  2018 Digitoxin Suppresses Store Operated Calcium Entry by Modulating Phosphorylation and the Pore Region of Orai1. SOCE
90  2018 Effect of autophagy and stromal interaction molecule 1 on podocyte epithelial-mesenchymal transition in diabetic nephropathy. ---
91  2018 Elevated plasma catecholamines functionally compensate for the reduced myogenic tone in smooth muscle STIM1 knockout mice but with deleterious cardiac effects. BP, sm-STIM1 KO
92  2018 Essential role for smooth muscle cell stromal interaction molecule-1 in myocardial infarction. MAP, MI, SMC
93  2018 Extracellular ATP activates store-operated Ca2+ entry in white adipocytes: functional evidence for STIM1 and ORAI1. PLC, si
94  2018 Golgi integral membrane protein 4 manipulates cellular proliferation, apoptosis, and cell cycle in human head and neck cancer. BrdU, GOLIM4
95  2018 High-Resolution Imaging of STIM/Orai Subcellular Localization Using Array Confocal Laser Scanning Microscopy. ER, FP
96  2018 Identification of molecular determinants that govern distinct STIM2 activation dynamics. ER, FRET, PM
97  2018 Impaired Store-Operated Calcium Entry and STIM1 Loss Lead to Reduced Insulin Secretion and Increased Endoplasmic Reticulum Stress in the Diabetic beta-Cell. ER, T2D
98  2018 Inhibition of stromal-interacting molecule 1-mediated store-operated Ca2+ entry as a novel strategy for the treatment of acquired imatinib-resistant gastrointestinal stromal tumors. GIST
99  2018 Inhibition of the NEDD8 conjugation pathway induces calcium-dependent compensatory activation of the pro-survival MEK/ERK pathway in acute lymphoblastic leukemia. ALL, PKC-beta2
100  2018 Inhibition of TRPC1-Dependent Store-Operated Calcium Entry Improves Synaptic Stability and Motor Performance in a Mouse Model of Huntington's Disease. ER, HD, MSNs, nSOC