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Abbreviation : Sal B
Long Form : salvianolic acid B
No. Year Title Co-occurring Abbreviation
2019 Anticonvulsant and anti-apoptosis effects of salvianolic acid B on pentylenetetrazole-kindled rats via AKT/CREB/BDNF signaling. i.p, IF, MAP2, PTZ, TUNEL
2019 Cardio-protective effects of salvianolic acid B on oxygen and glucose deprivation (OGD)-treated H9c2 cells. AMPK, MDM2, MEG3, OGD, qRT-PCR
2019 Dihydromyricetin and Salvianolic acid B inhibit alpha-synuclein aggregation and enhance chaperone-mediated autophagy. CMA, DHM
2019 Pharmacokinetics of salvianolic acid B, rosmarinic acid and Danshensu in rat after pulmonary administration of Salvia miltiorrhiza polyphenolic acid solution. DA, RosA, SMPA
2019 Protective effects of salvianolic acid B against hydrogen peroxide‑induced apoptosis of human umbilical vein endothelial cells and underlying mechanisms. AMPK, HUVECs, mTOR
2019 Sal B targets TAZ to facilitate osteogenesis and reduce adipogenesis through MEK-ERK pathway. TAZ
2019 Salvianolic acid B (Sal B) alleviates the decreased activity induced by prednisolone acetate on osteoblasts by up-regulation of bone formation and differentiation genes. GCs
2019 Salvianolic acid B ameliorates liver injury in a murine aGvHD model by decreasing inflammatory responses via upregulation of HO-1. aGVHD
2019 Salvianolic acid B inhibits Ang II-induced VSMC proliferation in vitro and intimal hyperplasia in vivo by downregulating miR-146a expression. VSMC
10  2019 Salvianolic acid B plays an anti-obesity role in high fat diet-induced obese mice by regulating the expression of mRNA, circRNA, and lncRNA. circRNA, lncRNA, WAT
11  2019 Salvianolic acid B remits LPS-induced injury by up-regulating miR-142-3p in MH7A cells. LPS, RA
12  2018 Antitumor properties of Salvianolic acid B against triple-negative and hormone receptor-positive breast cancer cells via ceramide-mediated apoptosis. TNBC
13  2018 Mechanism of salvianolic acid B neuroprotection against ischemia/reperfusion induced cerebral injury. MRI, qRT-PCR, TTC
14  2018 Polypharmacological Profiles Underlying the Antitumor Property of Salvia miltiorrhiza Root (Danshen) Interfering with NOX-Dependent Neutrophil Extracellular Traps. citH3, DHTI, MPO, NE, NETs, NOX
15  2018 Salvianolic acid B as an anti-emphysema agent I: In vitro stimulation of lung cell proliferation and migration, and protection against lung cell death, and in vivo lung STAT3 activation and VEGF elevation. HMVEC-L, JAK2, STAT3, VEGF
16  2018 Salvianolic acid B as an anti-emphysema agent II: In vivo reversal activities in two rat models of emphysema. CSE, MDA, MLI, MMP, MPO, PCNA, PPE, pSTAT3, STAT3, VEGF
17  2018 Salvianolic Acid B Enhances Hepatic Differentiation of Human Embryonic Stem Cells Through Upregulation of WNT Pathway and Inhibition of Notch Pathway. ESCs, Hes, LEF, TCF
18  2018 Salvianolic acid B inhibits glycolysis in oral squamous cell carcinoma via targeting PI3K/AKT/HIF-1alpha signaling pathway. HIF-1alpha, MMP, NGS, OSCC, PI3K
19  2018 Salvianolic acid B promotes neural differentiation of induced pluripotent stem cells via PI3K/AKT/GSK3beta/beta-catenin pathway. iPSCs, NSCs, PI3K
20  2018 Salvianolic Acid B Promotes the Survival of Random-Pattern Skin Flaps in Rats by Inducing Autophagy. ---
21  2018 SmbHLH37 Functions Antagonistically With SmMYC2 in Regulating Jasmonate-Mediated Biosynthesis of Phenolic Acids in Salvia miltiorrhiza. bHLH, JAs, JAZ, TF
22  2018 SmMYB111 Is a Key Factor to Phenolic Acid Biosynthesis and Interacts with Both SmTTG1 and SmbHLH51 in Salvia miltiorrhiza. bHLH, MYB, TTG1
23  2018 Synergistic Effects of Salvianolic Acid B and Puerarin on Cerebral Ischemia Reperfusion Injury. IS, Pue
24  2018 TGF-beta1 combined with Sal-B promotes cardiomyocyte differentiation of rat mesenchymal stem cells. BMSCs, CMs, cTnI, GATA4, TGF-beta1
25  2017 alphavbeta3 integrin receptor specific peptide modified, salvianolic acid B and panax notoginsenoside loaded nanomedicine for the combination therapy of acute myocardial ischemia. LPNs, PNS
26  2017 BMP-2 combined with salvianolic acid B promotes cardiomyocyte differentiation of rat bone marrow mesenchymal stem cells. BMP-2, BMSCs
27  2017 Calcium homeostasis and endoplasmic reticulum stress are involved in Salvianolic acid B-offered protection against cardiac toxicity of arsenic trioxide. ATO, ERS
28  2017 Coordination-driven assembly of catechol-modified chitosan for the kidney-specific delivery of salvianolic acid B to treat renal fibrosis. ECM, EMT, HChi-Ca-Sal B, UUO
29  2017 Decrease in the Generation of Amyloid-beta Due to Salvianolic Acid B by Modulating BACE1 Activity. AD, FL-APP, SwedAPP
30  2017 Effects of salvianolic acid B on L-type calcium channels and myocardial contractility in isolated rat ventricular myocytes and hERG K+ channels expressed in HEK293 cells. LQTS
31  2017 Function Analysis of Caffeoyl-CoA O-Methyltransferase for Biosynthesis of Lignin and Phenolic Acid in Salvia miltiorrhiza. MeJA
32  2017 LincRNA-p21 Inhibits the Wnt/beta-Catenin Pathway in Activated Hepatic Stellate Cells via Sponging MicroRNA-17-5p. alpha-SMA, HSCs, lincRNA-p21, lncRNAs, miRNAs
33  2017 Overexpression of SmMYC2 Increases the Production of Phenolic Acids in Salvia miltiorrhiza. ---
34  2017 Regulation of SIRT3/FOXO1 Signaling Pathway in Rats with Non-alcoholic Steatohepatitis by Salvianolic Acid B. IP, NASH, ROS, SD
35  2017 Salvianolic acid B and danshensu induce osteogenic differentiation of rat bone marrow stromal stem cells by upregulating the nitric oxide pathway. ALP, DSU, MSCs, NO, OCN, OPG, RANKL
36  2017 Salvianolic acid B attenuates doxorubicin-induced ER stress by inhibiting TRPC3 and TRPC6 mediated Ca2+ overload in rat cardiomyocytes. DOX, ER, TRPC
37  2017 Salvianolic acid B attenuates oxidized low-density lipoprotein-induced endothelial cell apoptosis through inhibition of oxidative stress, p53, and caspase-3 pathways. HUVECs, MDA, oxLDL, SOD
38  2017 Salvianolic Acid B Inhibits High-Fat Diet-Induced Inflammation by Activating the Nrf2 Pathway. COX-2, HF, HFD, iNOS, NF-kappaB, Nrf2
39  2017 Salvianolic acid B inhibits IL-1beta-induced inflammatory cytokine production in human osteoarthritis chondrocytes and has a protective effect in a mouse osteoarthritis model. OA
40  2017 Salvianolic acid B inhibits intermittent high glucose-induced INS-1 cell apoptosis through regulation of Bcl-2 proteins and mitochondrial membrane potential. MDA, MMP, PARP
41  2017 Salvianolic acid B prevents steroid-induced osteonecrosis of the femoral head via PPARgamma expression in rats. PPAR
42  2017 Salvianolic acid B protects hepatocytes from H2O2 injury by stabilizing the lysosomal membrane. Cat, LAMP1, MDA, PCC
43  2017 Salvianolic acid B regulates gene expression and promotes cell viability in chondrocytes. ---
44  2017 Simultaneous determination and pharmacokinetic study of four phenolic acids in rat plasma using UFLC-MS/MS after intravenous administration of salvianolic acid for injection. ESI, LA, MRM, PP, RA, SAFI, Sal D
45  2017 Synthesis and study the properties of StNPs/gum nanoparticles for salvianolic acid B-oral delivery system. StNPs
46  2017 The Protein Kinase SmSnRK2.6 Positively Regulates Phenolic Acid Biosynthesis in Salvia miltiorrhiza by Interacting with SmAREB1. ABRE, RA, SnRK2
47  2017 Treatment with salvianolic acid B restores endothelial function in angiotensin II-induced hypertensive mice. Ang II, DHE, HUVECs, ROS
48  2017 [Preparation and in vivo study of liposomes mediated by glycyrrhetinic acid derivative ligand 18-GA-Gly]. ---
49  2016 Cardioprotective effect of Salvianolic acid B on acute myocardial infarction by promoting autophagy and neovascularization and inhibiting apoptosis. AMI, HE
50  2016 Combination of chlorogenic acid and salvianolic acid B protects against polychlorinated biphenyls-induced oxidative stress through Nrf2. CADs, CGA, HO-1, Nrf2, SOD
51  2016 Development and validation of a UFLC-MS/MS method for determination of 7'(Z)-(8″S, 8‴S)-epi-salvianolic acid E, (7'R, 8'R, 8″S, 8‴S)-epi-salvianolic acid B and salvianolic acid B in rat plasma and its application to pharmacokinetic studies. ESI, MRM
52  2016 Effects of salvianolic acid B on growth inhibition and apoptosis induction of ovarian cancer SKOV3. ---
53  2016 Effects of ultrasonic processing on degradation of salvianolic acid B in aqueous solution. LC-MS
54  2016 Immobilization of salvianolic acid B-loaded chitosan microspheres distributed three-dimensionally and homogeneously on the porous surface of hydroxyapatite scaffolds. CS, HA
55  2016 MicroRNA-17-5p-activated Wnt/beta-catenin pathway contributes to the progression of liver fibrosis. HSC, MiRNAs, WIF1
56  2016 Mixed Aqueous Extract of Salvia Miltiorrhiza Reduces Blood Pressure through Inhibition of Vascular Remodelling and Oxidative Stress in Spontaneously Hypertensive Rats. AFs, DSS, PAL, ROS, Sal-A, SBP, SHR, SM, SMLP
57  2016 Production of rosmarinic acid and salvianolic acid B from callus culture of Salvia miltiorrhiza with cytotoxicity towards acute lymphoblastic leukemia cells. HPLC-DAD-MS, MS, RA, SM
58  2016 Protection of SAL B with H9C2 cells. ---
59  2016 Salvianolic Acid B (Sal B) Protects Retinal Pigment Epithelial Cells from Oxidative Stress-Induced Cell Death by Activating Glutaredoxin 1 (Grx1). Grx1, Nrf2, RPE, siRNA
61  2016 Salvianolic acid B ameliorates CNS autoimmunity by suppressing Th1 responses. EAE, MS
62  2016 Salvianolic Acid B Ameliorates Hyperglycemia and Dyslipidemia in db/db Mice through the AMPK Pathway. GLUT4, pACC, pAMPK, PPARalpha
63  2016 Salvianolic acid B improves the disruption of high glucose-mediated brain microvascular endothelial cells via the ROS/HIF-1alpha/VEGF and miR-200b/VEGF signaling pathways. HIF-1alpha, miR-200b, RBMECs, ROS, TJ, VEGF
64  2016 Salvianolic acid B improves vascular endothelial function in diabetic rats with blood glucose fluctuations via suppression of endothelial cell apoptosis. eNOS
65  2016 Salvianolic acid B induced upregulation of miR-30a protects cardiac myocytes from ischemia/reperfusion injury. IR, LDH, miRNAs
66  2016 Salvianolic acid B protects against doxorubicin induced cardiac dysfunction via inhibition of ER stress mediated cardiomyocyte apoptosis. DOX
67  2016 Salvianolic acid B reduced the formation of epidural fibrosis in an experimental rat model. EF, VEGF
68  2016 Salvianolic Acid B Restored Impaired Barrier Function via Downregulation of MLCK by microRNA-1 in Rat Colitis Model. miR-1, TNBS
69  2016 Salvianolic acid B stimulates osteogenesis in dexamethasone-treated zebrafish larvae. ALP, DEX, IOD, OC
70  2016 Salvianolic acid B, a novel autophagy inducer, exerts antitumor activity as a single agent in colorectal cancer cells. ---
71  2016 Simultaneous determination of tanshinones and polyphenolics in rat plasma by UPLC-MS/MS and its application to the pharmacokinetic interaction between them. CT, DSS, ESI, LLE, MRM, PAL, RA, SMB, T-I, TSIIA
72  2016 [Effects of salvianolic acid B on osteogenic differentiation of human periodontal ligament cells]. ALP, hPDLCs, MTT, OCN
73  2016 [The effect of Salvianolic Acid B on the Apoptosis of HUVECs Induced by Intermittent High Glucose]. HUVECs, MDA, NO, T-AOC
74  2015 Antidiabetic potential of salvianolic acid B in multiple low-dose streptozotocin-induced diabetes. MDA, MLDS, OGTT
75  2015 Antioxidant effect of salvianolic acid B on hippocampal CA1 neurons in mice with cerebral ischemia and reperfusion injury. MDA, NIH, NIM, NOS, SOD, T-AOC
76  2015 Differentiation of embryonic stem cells into cardiomyocytes used to investigate the cardioprotective effect of salvianolic acid B through BNIP3 involved pathway. BNIP3, ESCs, HIF-1alpha, MI
77  2015 Effects of salvianolic acid B on liver mitochondria of rats with nonalcoholic steatohepatitis. MDA, Mfn2, NASH, SOD
78  2015 Inhibition of Tanshinone IIA, salvianolic acid A and salvianolic acid B on Areca nut extract-induced oral submucous fibrosis in vitro. ANE, MOMFs, OSF, Sal-A, Tan IIA
79  2015 Inhibitory effect of salvianolate on human cytochrome P450 3A4 in vitro involving a noncompetitive manner. CYP450, HLMs, HPLC
80  2015 Protective effect of salvianolic acid B on NASH rat liver through restoring intestinal mucosal barrier function. AST, DAO, ET, SD, TC, TG
81  2015 Protective Effects and Mechanisms of Salvianolic Acid B Against H₂O₂-Induced Injury in Induced Pluripotent Stem Cell-Derived Neural Stem Cells. iPSCs, MMP, NSCs, pSTAT3, TIMP
82  2015 Salvianolic acid B accelerated ABCA1-dependent cholesterol efflux bytargeting PPAR-gamma and LXRalpha. ABCA1, LXRalpha, PPARgamma
83  2015 Salvianolic acid B attenuates lung inflammation induced by cigarette smoke in mice. BALF, CS, HO-1, i.p, IL-1beta, IL-6, MCP-1, NF-kappaB, Nrf2, TNF-alpha
84  2015 Salvianolic Acid B Down-regulates Matrix Metalloproteinase-9 Activity and Expression in Tumor Necrosis Factor-alpha-induced Human Coronary Artery Endothelial Cells. ERK, HCAECs, MMP-9, NF-kappaB, TNF-alpha
85  2015 Salvianolic acid B improves bone marrow-derived mesenchymal stem cell differentiation into alveolar epithelial cells type I via Wnt signaling. ALI, AQP, ATI, BMSCs, CM, LiCl
86  2015 Salvianolic acid B-induced microRNA-152 inhibits liver fibrosis by attenuating DNMT1-mediated Patched1 methylation. DNMT1, EMT, Hh, HSCs, miRNAs, Ptch1
87  2014 Cardiomyocyte-like cells differentiation from non beta-catenin expression mesenchymal stem cells. 5-aza, CLM, MSCs
88  2014 Development of Salvianolic acid B-Tanshinone II A-Glycyrrhetinic acid compound liposomes: formulation optimization and its effects on proliferation of hepatic stellate cells. GA, HSC, RP-HPLC, TSN
89  2014 Enhanced local bioavailability of single or compound drugs delivery to the inner ear through application of PLGA nanoparticles via round window administration. NPs, PL, PLGA, PNS, RW, RWM, TSIIA
90  2014 Expression of miR-106b-25 induced by salvianolic acid B inhibits epithelial-to-mesenchymal transition in HK-2 cells. alpha-SMA, EMT, miRNAs, TGF
91  2014 Hydrogen peroxide and nitric oxide are involved in salicylic acid-induced salvianolic acid B production in Salvia miltiorrhiza cell cultures. NO, SA
92  2014 In vivo distribution and pharmacokinetics of multiple active components from Danshen and Sanqi and their combination via inner ear administration. CSF, DAD, IT, PL, TSIIA
93  2014 Mechanism of action of salvianolic acid B by module-based network analysis. CMM, FAG-EC, GO, PIN
94  2014 Pathway engineering for phenolic acid accumulations in Salvia miltiorrhiza by combinational genetic manipulation. AtPAP1, SmCCR
95  2014 Salvianolic acid B inhibited PPARgamma expression and attenuated weight gain in mice with high-fat diet-induced obesity. IPGTT, IPITT, PPARgamma
96  2014 Salvianolic acid B inhibits atherogenesis of vascular cells through induction of Nrf2-dependent heme oxygenase-1. HO-1, Nrf2, PDGF
97  2014 Salvianolic acid B inhibits platelets as a P2Y12 antagonist and PDE inhibitor: evidence from clinic to laboratory. PDE
98  2014 Salvianolic acid B promotes bone formation by increasing activity of alkaline phosphatase in a rat tibia fracture model: a pilot study. ALP, HE
99  2014 Salvianolic acid B promotes osteogenesis of human mesenchymal stem cells through activating ERK signaling pathway. ERK, hMSCs
100  2014 Study on salvianolic acid B in the reduction of epidural fibrosis in laminectomy rats. EF, VEGF