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Abbreviation : TDGA
Long Form : 2-tetradecylglycidic acid
No. Year Title Co-occurring Abbreviation
2021 alpha-Tocopherol suppresses hepatic steatosis by increasing CPT-1 expression in a mouse model of diet-induced nonalcoholic fatty liver disease. alpha-Toc, HF, NAFLD
2008 Inhibition of mitochondrial fatty acid oxidation in vivo only slightly suppresses gluconeogenesis but enhances clearance of glucose in mice. G6P, GNG, mFAO, mRNA
2007 Gene expression profiling in livers of mice after acute inhibition of beta-oxidation. HNF-4, PGC-1alpha, PPAR-alpha
2006 Sustained activation of the mammalian target of rapamycin nutrient sensing pathway is associated with hepatic insulin resistance, but not with steatosis, in mice. mTOR
2005 Acute hepatic steatosis in mice by blocking beta-oxidation does not reduce insulin sensitivity of very-low-density lipoprotein production. CPT1, IRS, PI 3-kinase, TG
2004 Activation of leptin expression by an inhibitor of carnitine palmitoyltransferase-1. CPT1
2002 Partitioning of polyunsaturated fatty acid oxidation between mitochondria and peroxisomes in isolated rat hepatocytes studied by HPLC separation of oxidation products. PUFAs
2001 Participation of carnitine palmitoyltransferase in the synthesis of dipalmitoylphosphatidylcholine in rat alveolar type II cells. CPT, CPT I, DPPC, PC
2001 Studies on the transport of acetyl groups from peroxisomes to mitochondria in isolated liver cells oxidizing the polyunsaturated fatty acid 22:4n-6. ---
10  1999 2-Tetradecylglycidic acid, an inhibitor of carnitine palmitoyltransferase-1, induces myocardial hypertrophy via the AT1 receptor. AT1
11  1995 Carnitine palmitoyltransferase modulation of hepatic fatty acid metabolism and radio-HPLC evidence for low ketogenesis in neonatal pigs. ASP
12  1994 Evidence for the involvement of carnitine-dependent long-chain acyltransferases in neuronal triglyceride and phospholipid fatty acid turnover. CPT, PAC
13  1994 Phytanic acid must be activated to phytanoyl-CoA prior to its alpha-oxidation in rat liver peroxisomes. ETYA
14  1993 Regulation of pathways of extramitochondrial fatty acid oxidation and liver fatty acid-binding protein by long-chain monocarboxylic fatty acids in hepatocytes. Effect of inhibition of carnitine palmitoyltransferase I. L-FABP
15  1992 Effects of 2-tetradecylglycidic acid on rat platelet energy metabolism and aggregation. CPT I, MAR
16  1992 Peroxisomal fatty acid oxidation and inhibitors of the mitochondrial carnitine palmitoyltransferase I in isolated rat hepatocytes. CPT I
17  1991 Induction of myocardial hypertrophy after coronary ligation in rats decreases ventricular dilatation and improves systolic function. LV, MI
18  1990 Chronic inhibition of fatty acid oxidation: new model of diastolic dysfunction. ---
19  1989 Effects of inhibition of fatty acid oxidation on myocardial kinetics of 11C-labeled palmitate. ---
20  1989 Regulation of triglyceride mobilization in isolated hepatocytes by dibutyryl cyclic AMP and epinephrine. dbcAMP, FFA
21  1988 Effect of the fatty acid oxidation inhibitor 2-tetradecylglycidic acid (TDGA) on glucose and fatty acid oxidation in isolated rat soleus muscle. CPT-A
22  1988 Effects of acylcarnitine-transferase inhibitors on adenine nucleotide metabolism and ischemic tissue injury in isolated perfused rat heart. POCA
23  1987 A high-performance liquid chromatographic method for the enantiomeric analysis of the enzymatically synthesized coenzyme A ester of 2-tetradecylglycidic acid. ---
24  1987 Does carnitine have a role in fat absorption? ---
25  1987 Ketone formation in the intestinal mucosa of infant rats. ---
26  1986 Action in vivo and in vitro of 2-tetradecylglycidic acid, 2-tetradecylglycidyl-CoA and 2-tetradecylglycidylcarnitine on hepatic carnitine palmitoyltransferase. CPT, CPT-A
27  1986 Effects of 2-tetradecylglycidic acid on myocardial function in swine hearts. ---
28  1986 Hepatocellular triglyceride synthesis and transfer to lipid droplets and nascent very low density lipoproteins. VLDL
29  1986 Reduction of ischemia-induced acyl carnitine accumulation by TDGA and its influence on lactate dehydrogenase release in diabetic rat hearts. LDH
30  1979 Inhibition of hepatic lipogenesis by 2-tetradecylglycidic acid. ---