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Abbreviation : TDGA
Long Form : 2-tetradecylglycidic acid
No. Year Title Co-occurring Abbreviation
1  2021 alpha-Tocopherol suppresses hepatic steatosis by increasing CPT-1 expression in a mouse model of diet-induced nonalcoholic fatty liver disease. alpha-Toc, HF, NAFLD
2  2008 Inhibition of mitochondrial fatty acid oxidation in vivo only slightly suppresses gluconeogenesis but enhances clearance of glucose in mice. G6P, GNG, mFAO, mRNA
3  2007 Gene expression profiling in livers of mice after acute inhibition of beta-oxidation. HNF-4, PGC-1alpha, PPAR-alpha
4  2006 Sustained activation of the mammalian target of rapamycin nutrient sensing pathway is associated with hepatic insulin resistance, but not with steatosis, in mice. mTOR
5  2005 Acute hepatic steatosis in mice by blocking beta-oxidation does not reduce insulin sensitivity of very-low-density lipoprotein production. CPT1, IRS, PI 3-kinase, TG
6  2004 Activation of leptin expression by an inhibitor of carnitine palmitoyltransferase-1. CPT1
7  2002 Partitioning of polyunsaturated fatty acid oxidation between mitochondria and peroxisomes in isolated rat hepatocytes studied by HPLC separation of oxidation products. PUFAs
8  2001 Participation of carnitine palmitoyltransferase in the synthesis of dipalmitoylphosphatidylcholine in rat alveolar type II cells. CPT, CPT I, DPPC, PC
9  2001 Studies on the transport of acetyl groups from peroxisomes to mitochondria in isolated liver cells oxidizing the polyunsaturated fatty acid 22:4n-6. ---
10  1999 2-Tetradecylglycidic acid, an inhibitor of carnitine palmitoyltransferase-1, induces myocardial hypertrophy via the AT1 receptor. AT1
11  1995 Carnitine palmitoyltransferase modulation of hepatic fatty acid metabolism and radio-HPLC evidence for low ketogenesis in neonatal pigs. ASP
12  1994 Evidence for the involvement of carnitine-dependent long-chain acyltransferases in neuronal triglyceride and phospholipid fatty acid turnover. CPT, PAC
13  1994 Phytanic acid must be activated to phytanoyl-CoA prior to its alpha-oxidation in rat liver peroxisomes. ETYA
14  1993 Regulation of pathways of extramitochondrial fatty acid oxidation and liver fatty acid-binding protein by long-chain monocarboxylic fatty acids in hepatocytes. Effect of inhibition of carnitine palmitoyltransferase I. L-FABP
15  1992 Effects of 2-tetradecylglycidic acid on rat platelet energy metabolism and aggregation. CPT I, MAR
16  1992 Peroxisomal fatty acid oxidation and inhibitors of the mitochondrial carnitine palmitoyltransferase I in isolated rat hepatocytes. CPT I
17  1991 Induction of myocardial hypertrophy after coronary ligation in rats decreases ventricular dilatation and improves systolic function. LV, MI
18  1990 Chronic inhibition of fatty acid oxidation: new model of diastolic dysfunction. ---
19  1989 Effects of inhibition of fatty acid oxidation on myocardial kinetics of 11C-labeled palmitate. ---
20  1989 Regulation of triglyceride mobilization in isolated hepatocytes by dibutyryl cyclic AMP and epinephrine. dbcAMP, FFA
21  1988 Effect of the fatty acid oxidation inhibitor 2-tetradecylglycidic acid (TDGA) on glucose and fatty acid oxidation in isolated rat soleus muscle. CPT-A
22  1988 Effects of acylcarnitine-transferase inhibitors on adenine nucleotide metabolism and ischemic tissue injury in isolated perfused rat heart. POCA
23  1987 A high-performance liquid chromatographic method for the enantiomeric analysis of the enzymatically synthesized coenzyme A ester of 2-tetradecylglycidic acid. ---
24  1987 Does carnitine have a role in fat absorption? ---
25  1987 Ketone formation in the intestinal mucosa of infant rats. ---
26  1986 Action in vivo and in vitro of 2-tetradecylglycidic acid, 2-tetradecylglycidyl-CoA and 2-tetradecylglycidylcarnitine on hepatic carnitine palmitoyltransferase. CPT, CPT-A
27  1986 Effects of 2-tetradecylglycidic acid on myocardial function in swine hearts. ---
28  1986 Hepatocellular triglyceride synthesis and transfer to lipid droplets and nascent very low density lipoproteins. VLDL
29  1986 Reduction of ischemia-induced acyl carnitine accumulation by TDGA and its influence on lactate dehydrogenase release in diabetic rat hearts. LDH
30  1979 Inhibition of hepatic lipogenesis by 2-tetradecylglycidic acid. ---