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Abbreviation : TFEC
Long Form : S-(1,1,2,2-tetrafluoroethyl)-L-cysteine
No. Year Title Co-occurring Abbreviation
2006 Cytosolic heat shock proteins and heme oxygenase-1 are preferentially induced in response to specific and localized intramitochondrial damage by tetrafluoroethylcysteine. alpha-KGDH, ER, HO-1, HSP60, mtHSP70
2005 Aminotransferase, L-amino acid oxidase and beta-lyase reactions involving L-cysteine S-conjugates found in allium extracts. Relevance to biological activity? GTK, SAC, SAMC
2005 BCL-xL overexpression effectively protects against tetrafluoroethylcysteine-induced intramitochondrial damage and cell death. KGDH
2004 Kidney injury molecule-1: a tissue and urinary biomarker for nephrotoxicant-induced renal injury. KIM-1
2003 Renal cysteine conjugate C-S lyase mediated toxicity of halogenated alkenes in primary cultures of human and rat proximal tubular cells. AOAA, CDFEC, DCVC, DCVG, gamma-GT, GTK, TCVC
2002 Toxic, halogenated cysteine S-conjugates and targeting of mitochondrial enzymes of energy metabolism. DCVC, mitAspAT, PDHC, PLP
1999 Inhibition of select mitochondrial enzymes in PC12 cells exposed to S-(1,1,2,2-tetrafluoroethyl)-L-cysteine. AspAT, KGDHC, PDHC
1999 The roles of caspase-3 and bcl-2 in chemically-induced apoptosis but not necrosis of renal epithelial cells. DCVC, PARP
1998 The nephrotoxicity and hepatotoxicity of 1,1,2,2-tetrafluoroethyl-L-cysteine in the rat. ---
10  1996 Induction of FGF-7 after kidney damage: a possible paracrine mechanism for tubule repair. FGF, RPTE
11  1994 Cytosolic C-S lyase activity in human kidney samples-relevance for the nephrotoxicity of halogenated alkenes in man. 4-BPC, BTC, DCVC, TCPC
12  1993 Differential cellular effects in the toxicity of haloalkene and haloalkane cysteine conjugates to rabbit renal proximal tubules. AOAA, DCVC, RPT
13  1993 Examination of the structure-toxicity relationships of L-cysteine-S-conjugates of halogenated alkenes and their corresponding mercapturic acids in rat renal tissue slices. 1,2-DCVC, CTFEC, DBDFEC, DCDFEC
14  1993 Mitochondrial HSP60 (P1 protein) and a HSP70-like protein (mortalin) are major targets for modification during S-(1,1,2,2-tetrafluoroethyl)-L-cysteine-induced nephrotoxicity. ---
15  1992 Formation of mitochondrial phospholipid adducts by nephrotoxic cysteine conjugate metabolites. CTFC
16  1992 In vivo detection and characterization of protein adducts resulting from bioactivation of haloethene cysteine S-conjugates by 19F NMR: chlorotrifluoroethene and tetrafluoroethene. CTFC
17  1991 Detection of cysteine conjugate metabolite adduct formation with specific mitochondrial proteins using antibodies raised against halothane metabolite adducts. ---
18  1991 Formation of difluorothionoacetyl-protein adducts by S-(1,1,2,2-tetrafluoroethyl)-L-cysteine metabolites: nucleophilic catalysis of stable lysyl adduct formation by histidine and tyrosine. ---
19  1991 Role of lipid peroxidation in renal proximal tubule cell death induced by haloalkene cysteine conjugates. BHT, CTFC, DCVC, DPPD, MDA, PCBC
20  1990 The effect of haloalkene cysteine conjugates on rat renal glutathione reductase and lipoyl dehydrogenase activities. DCVC, HCBD, N-acetyl PCBC
21  1990 The effects of haloalkene cysteine conjugates on cytosolic free calcium levels in suspensions of rat renal proximal tubules. DCVC, PCBC
22  1989 Cysteine conjugate beta-lyase of rat kidney cytosol: characterization, immunocytochemical localization, and correlation with hexachlorobutadiene nephrotoxicity. DCVC, HCBD