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Abbreviation : TGF alpha
Long Form : transforming growth factor alpha
No. Year Title Co-occurring Abbreviation
2019 ErbB4 point mutation in CU3 inbred rats affects gonadotropin-releasing-hormone neuronal function via compromised neuregulin-stimulated prostaglandin E2 release from astrocytes. CU3, GnRH, PGE2
2019 Protein kinase A-mediated phosphorylation of naked cuticle homolog 2 stimulates cell-surface delivery of transforming growth factor-alpha for epidermal growth factor receptor transactivation. AKAP12, EGFR, GPCR, MDCK, MMP, NKD2, PGE2, PKA, VIP
2018 Amniotic Fluid Angiogenic and Inflammatory Factor Profiling in Foetal Down Syndrome. Ang-1, DS, EGF, IL-12p40, IL-1b, IL-4, MCP-2, MMP-1, MMP-9, PECAM-1, VEGFR-3, VEGFR2
2018 Generic Workflow for Mapping of Complex Disulfide Bonds Using In-Source Reduction and Extracted Ion Chromatograms from Data-Dependent Mass Spectrometry. EGF, ISR, MS, XICs
2018 HER2 Activation Factors in Arsenite-Exposed Bladder Epithelial Cells. EGF, HER2, Hsp90, IL-6, NDRG1, NRG1, PMCA2, sE-cad
2018 Interaction Effect of RsaI and BamHI Polymorphisms of TGFalpha, BMP2 and BMP4 on the Occurrence of Non-Syndromic Cleft Lip and Palate in Iranian Patients. BMP2, NSCLP, PCR, RFLP
2018 Long non-coding RNA TP73-AS1 sponges miR-194 to promote colorectal cancer cell proliferation, migration and invasion via up-regulating TGFalpha. CRC, lncRNAs, qRT-PCR
2018 TGFalpha/HinfI Polymorphisms Contribute to Nonsyndromic Cleft Lip and Palate in Turkish Patients. ---
2018 The TGFalpha-EGFR-Akt signaling axis plays a role in enhancing proinflammatory chemokines in triple-negative breast cancer cells. EGFR, TNBC
10  2018 [Detection of Physiological Activity of Pharmaceuticals in Wastewater and River Water]. DIP, EQs, GPCR, WWTP
11  2017 Anti-tumor activity of an immunotoxin (TGFalpha-PE38) delivered by attenuated Salmonella typhimurium. EGFR
12  2017 Autocrine expression of the epidermal growth factor receptor ligand heparin-binding EGF-like growth factor in cervical cancer. CCL2, EGF, EGFR, GM-CSF
13  2017 Biomarker analysis of the NeoSphere study: pertuzumab, trastuzumab, and docetaxel versus trastuzumab plus docetaxel, pertuzumab plus trastuzumab, or pertuzumab plus docetaxel for the neoadjuvant treatment of HER2-positive breast cancer. ER, HER2, pCR
14  2017 ErbB activation signatures as potential biomarkers for anti-ErbB3 treatment in HNSCC. AREG, HNSCC, NRG1
15  2017 Evaluation of plasma cytokines in patients with cocaine use disorders in abstinence identifies transforming growth factor alpha (TGFalpha) as a potential biomarker of consumption and dual diagnosis. CUD, IFN-gamma, IL-17alpha, IL-4, IL-8, MIP-1alpha
16  2017 Expression of Epidermal Growth Factor Receptor and Transforming Growth Factor Alpha in Cancer Bladder: Schistosomal and Non-Schistosomal. EGFR
17  2017 Hypothalamic hamartoma with epilepsy: Review of endocrine comorbidity. CPP, GABA, GnRH, HH
18  2017 Influence of the HER receptor ligand system on sensitivity to cetuximab and trastuzumab in gastric cancer cell lines. AREG, EGF, HB-EGF
19  2017 Magnetic Resonance-Guided High-Intensity-Focused Ultrasound for Palliation of Painful Skeletal Metastases: A Pilot Study. ---
20  2016 Context-specific protection of TGFalpha null mice from osteoarthritis. DMM, OA, OARSI
21  2016 Decline in Proliferation and Immature Neuron Markers in the Human Subependymal Zone during Aging: Relationship to EGF- and FGF-Related Transcripts. EGFR, ErbB4, FGF-2, FGFR1, SEZ
22  2016 Distinct stages in the recognition, sorting, and packaging of proTGFalpha into COPII-coated transport vesicles. CNIH, COPII, ER
23  2016 TGFalpha expression in myeloid malignancies. AML, CML
24  2016 The proliferative phase underpins endometrial development: Altered cytokine profiles in uterine lavage fluid of women with idiopathic infertility. GE, IFN-gamma
25  2015 Biochemical characterization of three BLT receptors in zebrafish. 12-HHT, 5lo, LTA4H, LTB4, RT
26  2015 Detection of physiological activities of G protein-coupled receptor-acting pharmaceuticals in wastewater. GPCRs
27  2015 Effects of calcium and vitamin D3 on transforming growth factors in rectal mucosa of sporadic colorectal adenoma patients: a randomized controlled trial. ---
28  2015 Lysophosphatidylserine analogues differentially activate three LysoPS receptors. ---
29  2015 Perturbed meibomian gland and tarsal plate morphogenesis by excess TGFalpha in eyelid stroma. EGF
30  2015 Reduction in disease progression by inhibition of transforming growth factor alpha-CCL2 signaling in experimental posttraumatic osteoarthritis. CPII, mRNA, OA
31  2015 The induction of C/EBPbeta contributes to vitamin D inhibition of ADAM17 expression and parathyroid hyperplasia in kidney disease. EGFR, PTG, PTH, SHPT, VDR
32  2015 Transforming growth factors and receptor as potential modifiable pre-neoplastic biomarkers of risk for colorectal neoplasms. TGF-betaRII
33  2014 A distinct salivary secretory response mediated by the esophago-salivary reflex in patients with Barrett's esophagus: its potential pathogenetic implications. BE, CTRL, EGF
34  2014 Activation of the epidermal growth factor receptor: a series of twists and turns. EGF, EGFR
35  2014 Autocrine ligands of the epithelial growth factor receptor mediate inflammatory responses to diesel exhaust particles. AR, DEP, EGFR, HB, MAPK, PBEC
36  2014 Defining the conformation of the estrogen receptor complex that controls estrogen-induced apoptosis in breast cancer. LBD, MC2, SRC3, TPEs
37  2014 Generation and activity of a humanized monoclonal antibody that selectively neutralizes the epidermal growth factor receptor ligands transforming growth factor-alpha and epiregulin. EGF, EGFR, EREG
38  2014 Inflammatory molecular signature associated with infectious agents in psychosis. ACE, alpha 2M, CSF, HCs, IL-6R, SCF, SZ, Tg, TNFR2
39  2014 RNA-seq analysis reveals significant effects of EGFR signalling on the secretome of mesenchymal stem cells. EGFR, FI, MSCs
40  2013 Acquired resistance to cetuximab is associated with the overexpression of Ras family members and the loss of radiosensitization in head and neck cancer cells. HNSCC, UT5R9
41  2013 ADAM17 controls endochondral ossification by regulating terminal differentiation of chondrocytes. EGFR
42  2013 Biological properties of dehydrated human amnion/chorion composite graft: implications for chronic wound healing. bFGF, EGF, ELISA, G-CSF, ILs, MSCs, PDGF-AA, PlGF, TIMPs
43  2013 Differential regulation of gonadotropin receptors (fshr and lhcgr) by epidermal growth factor (EGF) in the zebrafish ovary. BTC, EGF, EGFR, HB-EGF
44  2013 Distinct effects of EGFR ligands on human mammary epithelial cell differentiation. AREG, EGF, EGFR, hTERT, MECs, PI3K
45  2013 EGFR-targeted granzyme B expressed in NK cells enhances natural cytotoxicity and mediates specific killing of tumor cells. EGFR, GrB, GrB-T, NK
46  2013 Met interacts with EGFR and Ron in canine osteosarcoma. EGFR, HGF, OSA, RTK
47  2013 miR-152 controls migration and invasive potential by targeting TGFalpha in prostate cancer cell lines. miRNAs, PCa
48  2013 Rac1 is required for matrix metalloproteinase 13 production by chondrocytes in response to fibronectin fragments. EGF, FN, MMP, OA, siRNA
49  2013 Recombinant expression and purification of a tumor-targeted toxin in Bacillus anthracis. ---
50  2013 TACE-dependent TGFalpha shedding drives triple-negative breast cancer cell invasion. EGFR, TACE, TNBC
51  2012 A disintegrin and metalloproteinase 17 (ADAM17) and epidermal growth factor receptor (EGFR) signaling drive the epithelial response to Staphylococcus aureus toxic shock syndrome toxin-1 (TSST-1). ADAM17, AREG, EGFR, HVECs, IL-8, SAgs, SDC1, TNFR1, TSS, TSST-1
52  2012 EGFR ligands exhibit functional differences in models of paracrine and autocrine signaling. AR, EGF, EGFR
53  2012 Expression of estrogen receptor alpha and growth factors in human prolactinoma and its correlation with clinical features and gender. bFGF, ERalpha, TGF-betaRII
54  2012 Gefitinib and gemcitabine coordinately inhibited the proliferation of cholangiocarcinoma cells. CCC, EGFR, ERK
55  2012 Hypoxia induces gefitinib resistance in non-small-cell lung cancer with both mutant and wild-type epidermal growth factor receptors. EGFR, HIF-1alpha, NSCLC
56  2012 Increased concentrations of growth factors and activation of the EGFR system in breast cancer. AREG, BTC, EGF, EREG, FISH, HB-EGF, IHC, pHER2, pEGFR
57  2012 Intracellular pH regulation by Na⁺/H⁺ exchanger-1 (NHE1) is required for growth factor-induced mammary branching morphogenesis. MIA, NHE1
58  2012 Meprinalpha transactivates the epidermal growth factor receptor (EGFR) via ligand shedding, thereby enhancing colorectal cancer cell proliferation and migration. EGF, EGFR
59  2012 Pierre Menetrier and his disease. EGFR
60  2012 Pituitary adenylate cyclase-activating polypeptide causes tyrosine phosphorylation of the epidermal growth factor receptor in lung cancer cells. EGFR, NSCLC, PACAP
61  2012 Quantitative study of cytotoxic T-lymphocyte immunotherapy for nasopharyngeal carcinoma. CTL, EGFR, NPC
62  2012 Study of transforming growth factor alpha for the maintenance of human embryonic stem cells. hESCs
63  2012 TGFalpha shedding assay: an accurate and versatile method for detecting GPCR activation. AP-TGFalpha, GPCR
64  2012 Transforming growth factor alpha (TGFalpha) regulates granulosa cell tumor (GCT) cell proliferation and migration through activation of multiple pathways. GCT, GCTs
65  2012 Transforming growth factor alpha controls the transition from hypertrophic cartilage to bone during endochondral bone growth. ---
66  2012 Transforming growth factor alpha immunoreactivity. A study in hepatocellular carcinoma and in non-neoplastic liver tissue. HCC
67  2012 Transforming growth factor-alpha induces endothelin receptor A expression in osteoarthritis. OA
68  2012 Transforming growth factor-alpha mRNA expression and its possible roles in mouse endometrial stromal cells. IGF1, IGFBP-3, MMP
69  2011 AP1-dependent repression of TGFalpha-mediated MMP9 upregulation by PPARdelta agonists in keratinocytes. MMP9, PPARs
70  2011 ATP differentially upregulates fibroblast growth factor 2 and transforming growth factor alpha in neonatal and adult mice: effect on neuroproliferation. BrdU, FGF-2, OE, PPADS
71  2011 Gastric juice prostaglandins and peptide growth factors as potential markers of chronic atrophic gastritis, intestinal metaplasia and gastric cancer: their potential clinical implications based on this pilot study. ADCA, CAG, EGF, HP, IM, RIAs
72  2011 Inhibition of ERK oscillations by ionizing radiation and reactive oxygen species. EGFR, ERK, ROS, TPA
73  2011 LPA-producing enzyme PA-PLA₁alpha regulates hair follicle development by modulating EGFR signalling. EGFR, IRS, LPA, TACE
74  2011 Manganese induces IGF-1 and cyclooxygenase-2 gene expressions in the basal hypothalamus during prepubertal female development. COX-2, IGF-1, IGF-1R, LHRH, MBH, Mn, POA/AVPV
75  2011 Minimal cooperation between mutant Hras and c-myc or TGFalpha in the regulation of mouse hepatocyte growth or transformation in vivo. ---
76  2011 Plant polyphenols differentially modulate inflammatory responses of human keratinocytes by interfering with activation of transcription factors NFkappaB and AhR and EGFR-ERK pathway. AhR, EGFR, LPS, PPs
77  2011 Polymorphism of the epidermal growth factor receptor extracellular ligand binding domain: the dimer interface depends on domain stabilization. EGF, EGFRs, MD
78  2011 Prepubertal ethanol exposure alters hypothalamic transforming growth factor-alpha and erbB1 receptor signaling in the female rat. EtOH, LHRH, MBH, PCR
79  2011 Suppression by heat shock protein 20 of hepatocellular carcinoma cell proliferation via inhibition of the mitogen-activated protein kinases and AKT pathways. ERK, HCC, HSP, HSP20, JNK, MAPKs
80  2011 Transforming growth factor alpha transforms astrocytes to a growth-supportive phenotype after spinal cord injury. EGFR, SCI
81  2010 Analysis of receptor tyrosine kinases (RTKs) and downstream pathways in chordomas. CSF1R, EGF, mTOR, RTKs
82  2010 Carbachol induces TGF-alpha expression and colonic epithelial cell proliferation in sensory-desensitised rats. ---
83  2010 Central precocious puberty due to hypothalamic hamartomas correlates with anatomic features but not with expression of GnRH, TGFalpha, or KISS1. CPP, GnRH, GnRHR
84  2010 Chronic pancreatitis in mice by treatment with choline-deficient ethionine-supplemented diet. CDE, EGFR, PDA, Spink3, TCs
85  2010 Early weaning accelerates the differentiation of mucous neck cells in rat gastric mucosa: possible role of TGFalpha/EGFR. EGFR, EW
86  2010 Effect of transforming growth factor alpha overexpression on urogenital organ development in mouse. AP, DLP, EGFR, Tg, VP, WT
87  2010 ETS-1 oncogenic activity mediated by transforming growth factor alpha. ---
88  2010 IL-24 is expressed during wound repair and inhibits TGFalpha-induced migration and proliferation of keratinocytes. IL, mda-7, NHEKs
89  2010 Inhibition of PI3K by PX-866 prevents transforming growth factor-alpha-induced pulmonary fibrosis. EGFR, PI3K
90  2010 Retention of progenitor cell phenotype in otospheres from guinea pig and mouse cochlea. bFGF, EGF
91  2010 Rho/ROCK and MEK/ERK activation by transforming growth factor-alpha induces articular cartilage degradation. EGFR, ERK, MAPK, OA
92  2009 Activation of epidermal growth factor receptor ErbB1 attenuates inhibitory synaptic development in mouse dentate gyrus. EGF, EPSCs, IPSCs
93  2009 ADAMTS1 and MMP1 proteolytically engage EGF-like ligands in an osteolytic signaling cascade for bone metastasis. AREG, EGF, EGFR, HB-EGF, MMP1, OPG
94  2009 Amphiregulin is much more abundantly expressed than transforming growth factor-alpha and epidermal growth factor in human follicular fluid obtained from patients undergoing in vitro fertilization-embryo transfer. AR, EGF
95  2009 Decreased growth factor expression through RNA interference inhibits development of mouse preimplantation embryos. EGF, siRNA
96  2009 Differential regulation of betacellulin and heparin-binding EGF-like growth factor in cultured zebrafish ovarian follicle cells by EGF family ligands. AR, BTC, EGF, HB-EGF
97  2009 Estradiol, progesterone, and transforming growth factor alpha regulate insulin-like growth factor binding protein-3 (IGFBP3) expression in mouse endometrial cells. IGF1, IGFBP-3
98  2009 Expression of ErbB receptors and their cognate ligands in gastric and colon cancer cell lines. EGF
99  2009 Extracts of Sarcoptes scabiei De Geer downmodulate secretion of IL-8 by skin keratinocytes and fibroblasts and of GM-CSF by fibroblasts in the presence of proinflammatory cytokines. CTACK, G-CSF, GM-CSF, GROalpha, ICAM-1, IL, TNF
100  2009 Integrin signal masks growth-promotion activity of HB-EGF in monolayer cell cultures. EGFR, FAK, HB-EGF, RTKs