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Abbreviation : TGr
Long Form : 6-thioguanine-resistant
No. Year Title Co-occurring Abbreviation
1999 Bromodeoxyuridine labelling as an alternative method to identify 6-thioguanine-resistant mutant lymphocytes in humans. anti-BrdU, TG
1998 Mutational response at the splenic T-lymphocyte hprt locus in mice treated as neonates: contrasting effects of the carcinogens N-ethyl-N-nitrosourea, dimethylnitrosamine, and 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine. DMN, ENU, MFs, PhIP
1997 Analysis of mutations in the K-ras and p53 genes of lung tumors and in the hprt gene of 6-thioguanine-resistant T-lymphocytes from rats treated with 1,6-dinitropyrene. DNP
1997 Increased frequency of specific locus mutation following human cytomegalovirus infection. HCMV, hprt, PFU
1997 Influence of donor age on the cytotoxicity and mutagenicity of ethylnitrosourea in cultured human T-lymphocytes. ENU, HPRT, MF
1997 The mutagenic response at the ouabain resistance locus in T cells of mice exposed to N-ethyl-N-nitrosourea parallels the response at the Hprt locus and correlates with mutation target size. ENU, MF, Oua
1996 Comparison of the frequency of T-cell receptor mutants and thioguanine resistance induced by X-rays and ethylnitrosourea in cultured human blood T-lymphocytes. ENU, TCR
1996 DNA sequence analysis of hprt mutations in lymphocytes from Sprague-Dawley rats treated with 7,12-dimethylbenz[a]anthracene. bp, DMBA, PCR
1996 Lymphocyte mutant frequency in relation to DNA adduct formation in rats treated with tumorigenic doses of the mammary gland carcinogen 7,12-dimethylbenz[a]anthracene. DMBA
10  1996 Quantitative and qualitative effect of gamma-ray dose-rate on mutagenesis in human lymphoblastoid cells. ---
11  1995 Analysis of in vivo mutation induced by N-ethyl-N-nitrosourea in the hprt gene of rat lymphocytes. ENU
12  1995 Effect of dietary components on hprt mutant frequencies in human T-lymphocytes. Mf
13  1995 Mutagenicity in vitro of 3,4-dichloro-5-hydroxy-2(5H)-furanone (mucochloric acid), a chlorine disinfection by-product in drinking water. CHO, hprt
14  1995 Spectrum of in vivo hprt mutations in T lymphocytes from atomic bomb survivors. I. Sequence alterations in cDNA. hprt, PCR, RT
15  1994 Determination of hprt mutant frequencies in T-lymphocytes from a healthy pediatric population: statistical comparison between newborn, children and adult mutant frequencies, cloning efficiency and age. age, CE, MF
16  1994 Induction of gene mutation in mammalian cells by 3-chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone (MX), a chlorine disinfection by-product in drinking water. CHO, MX
17  1994 The effect of T-lymphocyte 'clonality' on the calculated hprt mutation frequency occurring in vivo in humans. TCR
18  1993 Cytotoxic and genotoxic properties of tert.-butyl-p-quinone (TBQ) in an in vitro assay system with Chinese hamster V79 cells and in strain D7 of Saccharomyces cerevisiae. SCE, TBQ
19  1993 Detection of 6-thioguanine-resistant human peripheral blood lymphocytes using 5-bromodeoxyuridine labeling in combination with immunocytochemical staining. BrdU, LIc, PHA, VF
20  1993 DNA adduct formation in relation to lymphocyte mutations and lung tumor induction in F344 rats treated with the environmental pollutant 1,6-dinitropyrene. ---
21  1993 The effect of time after treatment, treatment schedule and animal age on the frequency of 6-thioguanine-resistant T-lymphocytes induced in Fischer 344 rats by N-ethyl-N-nitrosourea. ENU
22  1992 Analysis of X-ray-induced HPRT mutations in CHO cells: insertion and deletions. CHO, hprt, PCR
23  1992 Evaluation of genotoxicity of tert.-butylhydroquinone in an hepatocyte-mediated assay with V79 Chinese hamster lung cells and in strain D7 of Saccharomyces cerevisiae. SCE, tBHQ
24  1992 Induction of thioguanine-resistant mutations in human uroepithelial cells by 4-aminobiphenyl and its N-hydroxy derivatives. ABP, HGPRT, HUC, N-OAc-AABP, N-OH-AABP, N-OH-ABP
25  1992 Restriction fragment pattern analysis of HPRT mutations induced in rat-liver epithelial cells by alkylating and arylating agents. AAF, ARL, DMBA, HPRT, MNNG, RFP
26  1991 Cytosine arabinoside enhancement of gamma irradiation induced mutations in human T-lymphocytes. TCR
27  1991 Determination of 6-thioguanine resistant lymphocytes in human blood by immunohistochemical antibromodeoxyuridine staining. BrdU
28  1991 Genotoxicity of 1-nitronaphthalene in Chinese hamster V79 cells. 1-NN, SCE
29  1991 Induction of 6-thioguanine-resistant lymphocytes in Fischer 344 rats following in vivo exposure to N-ethyl-N-nitrosourea and cyclophosphamide. CEs, CP, ENU, PHA, TG
30  1991 Induction of mutation in V79 Chinese hamster cells by tetrachlorohydroquinone, a metabolite of pentachlorophenol. HPRT, LOED, ouar, TCC, TCHQ
31  1991 Study of the biological effects of theophylline on V79 cells: viability, membrane permeability, and metabolic cooperation. TGS
32  1990 6-Thioguanine-resistant T-lymphocyte autoradiographic assay. Determination of variation frequencies in individuals suspected of radiation exposure. HGPRT
33  1990 Comparative genotoxicity of 3 procarcinogens in V79 cells as related to glutathione S-transferase activity of hepatocytes from untreated rats and those fed 2% butylated hydroxyanisole. AFB1, BHA, DMBA, DMN, GST, MN, OuR, SCE
34  1990 In vitro induction, expression and selection of thioguanine-resistant mutants with human T-lymphocytes. hprt, PHA, TCGF
35  1990 Southern-blot analyses of human T-lymphocyte mutants induced in vitro by gamma-irradiation. hprt, TCR
36  1989 6-Thioguanine resistant T-lymphocyte determination as a possible indicator of human ionizing radiation exposure. ---
37  1989 Cloning of in vivo-derived thioguanine-resistant human B cells. EB, HPRT, PBMC
38  1989 Longitudinal study of the in vivo hprt mutant frequency in human T-lymphocytes as determined by a cell cloning assay. ---
39  1988 Elevated frequencies of 6-thioguanine-resistant lymphocytes in multiple sclerosis patients treated with cyclophosphamide: a prospective study. CP, MS, Vfs
40  1988 Mutagenicity monitoring in humans by autoradiographic assay for mutant T lymphocytes. ---
41  1987 A 6-thioguanine-resistant variant of the rat mammary adenocarcinoma 13762 that is more immunogenic. CMC
42  1987 Differential hypersensitivity of xeroderma pigmentosum lymphoblastoid cell lines to ultraviolet light mutagenesis. XP
43  1987 Identification of variants of the basophilic leukemia (RBL-2H3) cells that have defective phosphoinositide responses to antigen and stimulants of guanosine 5'-triphosphate-regulatory proteins. BUDRR
44  1987 Species specificity in the metabolism of N-nitrosobis(2-oxopropyl)amine and N-nitroso(2-hydroxypropyl)(2-oxopropyl)amine to mutagens by isolated rat and hamster hepatocytes. HPOP, ouar
45  1986 Analyses of mutation in pSV2gpt-transformed CHO cells. CHO, XPRT
46  1986 The restriction endonuclease Alu I induces chromosomal aberrations and mutations in the hypoxanthine phosphoribosyltransferase locus, but not in the Na+/K+ ATPase locus in V79 hamster cells. HPRT, ouar
47  1985 A study of the frequency of sister-chromatid exchange and of thioguanine-resistant cells in mouse spleen lymphocytes after in vivo exposure to ethylnitrosourea. ENU, SCE
48  1985 Analysis of mammary tumour cell metastasis and release of bound n-acetylneuraminic acid. NANA
49  1985 Induction of mitochondrial mutations in human cells by methotrexate. CAPR, MTX
50  1985 Somatic gene mutations in vivo as indicated by the 6-thioguanine-resistant T-lymphocytes in human blood. HPRT, MFs, T-Lys, Vfs
51  1985 Spontaneous 6-thioguanine-resistant lymphocytes in Fanconi anemia patients and their heterozygous parents. FA
52  1984 Circulating immune complexes in rats bearing 6-thioguanine-resistant variants of the 13762 mammary adenocarcinoma. IC
53  1984 Induction of 6-thioguanine-resistant mutants and SCEs by 3 chemical mutagens (EMS, ENU and MMC) in cultured human blood lymphocytes. EMS, ENU, MMC, SCEs
54  1983 Detection of the carrier state for an X-linked disorder, the Lesch-Nyhan syndrome, by the use of lymphocyte cloning. ---
55  1983 Evidence that thioguanine-resistant lymphocytes detected by autoradiography are mutant cells. ---
56  1983 Limiting factors of the V79 cell metabolic cooperation assay for tumor promoters. DMSO, DNT, TPA
57  1982 A 6-thioguanine-resistant variant of the 13762 cell line which is no longer tumorigenic or metastatic. ---
58  1982 The cytotoxic and mutagenic effects of 5-bromodeoxyuridine-plus-black-light treatment in cultured mammalian cells. BrdU, CHO
59  1982 The induction of specific-locus mutations and sister-chromatid exchanges by 5-bromo- and 5-chloro-deoxyuridine. SCE
60  1981 Different sensitivity to cytotoxic agents of internal and external cells of spheroids composed of thioguanine-resistant and sensitive cells. ---
61  1981 Effects of metabolic inhibitors on cel lethality and mutation induction in Chinese hamster cells. II. The effect of posttreatment with non-toxic concentrations of thymidine. AZR, EMS, ENU, IMF, MNU
62  1980 Ethylnitrosourea-induced mutagenesis in asynchronous and synchronous Chinese hamster ovary cells. CHO, ENU, ouar
63  1979 Cell-cycle dependency of BUdR-induced mutation for six genetic markers in cultured mammalian cells. Ara-Cr, MTXr, ouar
64  1979 Enumeration of 6-thioguanine-resistant peripheral blood lymphocytes in man as a potential test for somatic cell mutations arising in vivo. DAPr, LN, PBLs, PHA, Vf's
65  1979 Ultraviolet mutagenesis of normal and xeroderma pigmentosum variant human fibroblasts. UV