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Abbreviation : TIM3
Long Form : T cell immunoglobulin and mucin domain 3
No. Year Title Co-occurring Abbreviation
2020 CD8+ T cells exhaustion induced by myeloid-derived suppressor cells in myelodysplastic syndromes patients might be through TIM3/Gal-9 pathway. MDS, MDSCs
2019 Clinicopathological implications of TIM3+ tumor-infiltrating lymphocytes and the miR-455-5p/Galectin-9 axis in skull base chordoma patients. Gal9, KPS, LRFS, OS, TIL
2019 Clostridium butyricum alleviates intestinal low-grade inflammation in TNBS-induced irritable bowel syndrome in mice by regulating functional status of lamina propria dendritic cells. AWR, C. butyricum, DCs, IBS, LPDCs
2019 Elevated TIM3 expression of T helper cells affects immune system in patients with myelodysplastic syndrome. MDS, Th
2019 Frequent germline mutations of HAVCR2 in sporadic subcutaneous panniculitis-like T-cell lymphoma. SPTCL
2019 Significance of TIM3 expression in cancer: From biology to the clinic. ---
2019 The clinical significance of myeloid-derived suppressor cells in dengue fever patients. DF, IFN-alpha, MDSCs, NDF, RANTES
2019 Various checkpoint molecules, and tumor-infiltrating lymphocytes in common pediatric solid tumors: Possibilities for novel immunotherapy. BTLA, Gal-9, HVEM, LAG3, MHC-II, TILs
2018 Blockade of TIM3 relieves immunosuppression through reducing regulatory T cells in head and neck cancer. HNSCC
10  2018 Cytolytic Activity Score to Assess Anticancer Immunity in Colorectal Cancer. CRC, CTLA4, CYT, GzmA, ICMs, IDO1, LAG3, PD-L1, TILs
11  2018 The effects of resiquimod in an ovalbumin-induced allergic rhinitis model. AR, ELISAs, IF, OVA, PAS, qRT-PCR, Tim-1
12  2017 CXCR2+ MDSCs promote breast cancer progression by inducing EMT and activated T cell exhaustion. CTLA-4, EMT, LAG3, MDSCs, PDL1
13  2017 Plasma biomarkers of risk for death in a multicenter phase 3 trial with uniform transplant characteristics post-allogeneic HCT. GVHD, HCT, ST2
14  2017 Predictive Value of Clinical Findings and Plasma Biomarkers after Fourteen Days of Prednisone Treatment for Acute Graft-versus-host Disease. AUC, GVHD, NRM, sTNF-R1
15  2017 Synergistic effect of IL-12 and IL-18 induces TIM3 regulation of gammadelta T cell function and decreases the risk of clinical malaria in children living in Papua New Guinea. ---
16  2017 T-cell immunoglobulin mucin 3 blockade drives an antitumor immune response in head and neck cancer. HNSCC, MDSCs
17  2017 Understanding the checkpoint blockade in lung cancer immunotherapy. CTLA-4, KIRs, LAG3, NSCLC
18  2016 Clinical significance of Tim3-positive T cell subsets in patients with multiple sclerosis. ELISA, MS, PBMCs
19  2016 Increased TIM3+CD8+T cells in Myelodysplastic Syndrome patients displayed less perforin and granzyme B secretion and higher CD95 expression. MDS
20  2016 Ovarian carcinoma-infiltrating regulatory T cells were more potent suppressors of CD8(+) T cell inflammation than their peripheral counterparts, a function dependent on TIM3 expression. IL-10
21  2016 Plasma levels of Galectin-9 reflect disease severity in malaria infection. Gal-9, SM, UM
22  2015 Expression of coinhibitory receptors on T cells in the microenvironment of usual vulvar intraepithelial neoplasia is related to proinflammatory effector T cells and an increased recurrence-free survival. uVIN
23  2013 Costimulation-adhesion blockade is superior to cyclosporine A and prednisone immunosuppressive therapy for preventing rejection of differentiated human embryonic stem cells following transplantation. Fluc, hESC
24  2013 TIM3 expression by leukemic and non-leukemic myeloblasts. AML, MFI
25  2013 TIM3+FOXP3+ regulatory T cells are tissue-specific promoters of T-cell dysfunction in cancer. ---
26  2011 Prospects for TIM3-Targeted Antitumor Immunotherapy. ---
27  2011 T-cell immunoglobulin and mucin domain 3 genetic polymorphisms are associated with rheumatoid arthritis independent of a shared epitope status. RA, SE
28  2010 The inhibition of the T-cell immunoglobulin and mucin domain 3 (Tim3) pathway enhances the efficacy of tumor vaccine. ---
29  2010 Tim3 binding to galectin-9 stimulates antimicrobial immunity. Gal9
30  2010 Tim3 is upregulated and protective in nephrotoxic serum nephritis. NTS, NTS
31  2009 Lack of association of TIM3 polymorphisms and allergic phenotypes. SNPs