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Abbreviation : TIMP
Long Form : tissue inhibitor of metalloproteinase
No. Year Title Co-occurring Abbreviation
2020 Aesculetin Attenuates Alveolar Injury and Fibrosis Induced by Close Contact of Alveolar Epithelial Cells with Blood-Derived Macrophages via IL-8 Signaling. BALF, CXCR2, IL, mCM, MMP, PHMG, TNF
2020 An Anthocyanin-Enriched Extract from Vaccinium uliginosum Improves Signs of Skin Aging in UVB-Induced Photodamage. ERK, HPLC, JNK, MMP, TEWL, UVB
2020 Beneficial effects of N-acetylcysteine on protease-antiprotease balance in attenuating bleomycin-induced pulmonary fibrosis in rats. AECs, MMP, NAC, TGF-beta1
2020 Cigarette Smoke Extract Stimulates MMP-2 Production in Nasal Fibroblasts via ROS/PI3K, Akt, and NF-kappaB Signaling Pathways. CSE, MMP, ROS
2020 ClassC1 decoy oligodeoxynucleotide inhibits profibrotic genes expression in rat hepatic stellate cells. HSC, ODNs, TGF
2020 Concerted actions by MMPs, ADAMTS and serine proteases during remodeling of the cartilage callus into bone during osseointegration of hip implants. NE, OA, PR3, SLPI
2020 CpG postconditioning after reperfused myocardial infarction is associated with modulated inflammation, less apoptosis, and better left ventricular function. CpG, LAD, LV, MHC, MI, MMP, MMP-8, TLR9
2020 Cytokines, Angiogenesis, and Extracellular Matrix Degradation are Augmented by Oxidative Stress in Endometriosis. COX, ECM, IL, MMP, NF-kappaB, OS, VEGF
2020 Decreased Collagen Type I is Associated with Increased Metalloproteinase-2 Activity and Protein Expression of Leptin in the Myocardium of Obese Rats. ---
10  2020 Development of Postoperative Pain in Patients with End-Stage Knee Osteoarthritis Is Associated with Upregulation of Genes Related to Extracellular Matrix Degradation, Inflammation, and Apoptosis Measured in the Peripheral Blood before Knee Surgery. COX, DN4, IL, OA, PBMCs, ROC, TNF, VAS, WOMAC
11  2020 DNA methylation of MMPs and TIMPs in atherothrombosis process in carotid plaques and blood tissues. DNAm, ISC-1, ISC-2, MMP
12  2020 Effect of prostaglandin analogs: Latanoprost, bimatoprost, and unoprostone on matrix metalloproteinases and their inhibitors in human trabecular meshwork endothelial cells. MMPs, TM
13  2020 Effects of a Matrix Metalloproteinase Inhibitor-Eluting Stent on In-Stent Restenosis. ISR, MMP, VSMCs
14  2020 Effects of exercise training on renal interstitial fibrosis and renin-angiotensin system in rats with chronic renal failure. ACE, MMP, RAS, TGF-beta1
15  2020 Evaluation of extracellular matrix protein expression and apoptosis in the uterosacral ligaments of patients with or without pelvic organ prolapse. Bax, Bcl-2, ECM, ER, IHC, MMP, POP, USL
16  2020 Evaluation of significant gene expression changes in congenital and acquired cholesteatoma. EGFR, MMP, SPSS
17  2020 High Serum Tissue Inhibitor of Matrix Metalloproteinase-1 Levels and Mortality in Patients with Spontaneous Intracerebral Hemorrhage. MMP, SIH
18  2020 Improvement of Impaired Motor Functions by Human Dental Exfoliated Deciduous Teeth Stem Cell-Derived Factors in a Rat Model of Parkinson's Disease. CNS, IGFBP-6, IPA, PD, SHED, SHED-CM, TGF-1
19  2020 Inhibiting the NLRP3 inflammasome with MCC950 ameliorates retinal neovascularization and leakage by reversing the IL-1beta/IL-18 activation pattern in an oxygen-induced ischemic retinopathy mouse model. Ang-2, ASC, CARD, CAS1, IL, MMP, NLRP3, OIR, PDGF-B, PDGFRbeta, RNV, VEGF, VEGFR
20  2020 Insulin-like growth factor-binding protein 3 inhibits angiotensin II-induced aortic smooth muscle cell phenotypic switch and matrix metalloproteinase expression. ACTA2, Ang, AoSMC, IGFBP-3, MMP, MYH11, SPP1, TAD
21  2020 Interplay between perivascular and perineuronal extracellular matrix remodelling in neurological and psychiatric diseases. CNS, ECM, MMPs
22  2020 Interstitial changes after reperfused myocardial infarction in swine: morphometric and genetic analysis. ECM, MI
23  2020 Irisin Recovers Osteoarthritic Chondrocytes In Vitro. ERK, hOAC, IL, iNOS, JNK, MAPK, MMP, NF-kappaB
24  2020 Knockdown of activated Cdc42-associated kinase inhibits human extravillous trophoblast migration and invasion and decreases protein expression of pho-Akt and matrix metalloproteinase. ACK1, CCK-8, EVTs, MMP, p-Akt, p-PI3K, PE
25  2020 Label-Free Quantitative Proteomics versus Antibody-Based Assays to Measure Neutrophil-Derived Enzymes in Saliva. ELISA, IFMA, LFQ, MMP, WB
26  2020 Matrix metalloproteinases regulate ECM accumulation but not larval heart growth in Drosophila melanogaster. ECM
27  2020 MiR-95-5p involves in the migration and invasion of trophoblast cells by targeting low density lipoprotein receptor-related protein 6. LRP6, miR, MMP, PE, qRT-PCR, WB
28  2020 MMPs, TIMPs and BMP-4 in medial rectus muscle obtained from intermittent exotropia patients and their clinical correlations. BMP, ELISA, IXT, MMP, MR
29  2020 Modulation of Immune Responses by Platelet-Derived ADAM10. ADAM, MMP
30  2020 Molecular mechanism of the effect of angiopoietin-like protein 8 on the proliferation, invasion and migration of placental trophoblasts in preeclampsia. ANGPTL8, MMP, PE, si
31  2020 Nebivolol Prevents Up-Regulation of Nox2/NADPH Oxidase and Lipoperoxidation in the Early Stages of Ethanol-Induced Cardiac Toxicity. MMP, SOD, TBARS
32  2020 Novel biomarkers of acute kidney injury in children: an update on recent findings. AKI, IGFBP, IL, NGAL
33  2020 Protective effects of desipramine on alveolar bone in experimental periodontitis. COX, IL, iNOS, MMP
34  2020 Resveratrol inhibits the tumor migration and invasion by upregulating TET1 and reducing TIMP2/3 methylation in prostate carcinoma cells. 5hmC, 5mC, PCa, RES, TET1
35  2020 Reversing UVB-induced photoaging with Hibiscus sabdariffa calyx aqueous extract. HSCAE, MITF, MMP, ROS, TRP-1, UVB
36  2020 Role of biomarkers of cardiac remodeling, myofibrosis, and inflammation in assessment of disease severity in euvolemic patients with chronic stable heart failure. CHF, GDF, NT-proBNP, sST2
37  2020 Role of extracellular matrix remodelling gene SNPs in keratoconus. MMP9, SNPs
38  2020 Role of Interleukin-17 in Pathogenesis of Intestinal Fibrosis in Mice. ELISA, IL, MMP, mRNA, TGF, TNBS, TNF
39  2020 SARS-CoV-2 induces transcriptional signatures in human lung epithelial cells that promote lung fibrosis. ACE, ADAM, AGT, COVID-19, CTGF, FN, SARS, TMPRSS, VEGF
40  2020 Shear Stress and Aortic Strain Associations With Biomarkers of Ascending Thoracic Aortic Aneurysm. miRNA, MMP, TAWSS, WSS
41  2020 Synovial fluid fingerprinting in end-stage knee osteoarthritis: a novel biomarker concept. AUC, esOA, IP-10, MCP, OA, PLS-DA, ROC, SF, TGF
42  2020 The alternatively spliced RECK transcript variant 3 is a predictor of poor survival for melanoma patients being upregulated in aggressive cell lines and modulating MMP gene expression in vitro. MMP, RECK
43  2020 The effect of frequent hemodialysis on matrix metalloproteinases, their tissue inhibitors, and FGF23: Implications for blood pressure and left ventricular mass modification in the Frequent Hemodialysis Network trials. FGF, FHN, LVM
44  2020 The Identification of Immune-Related Plasma Proteins Associated with Spontaneous Preterm Delivery and Intra-Amniotic Infection in Women with Premature Cervical Dilation or an Asymptomatic Short Cervix. AF, AUC, ELISA, IL, MMP, SPTD
45  2020 Three Tiaobu Feishen formulae reduces cigarette smoke-induced inflammation in human airway epithelial cells. AP, BJF, BYF, CSE, IL, LPS, MAPK, MMP, NF, PPAR, SOD, STAT, TBFS, TNF, YZF
46  2020 Tissue Inhibitor of Metalloproteinase 3 Deficiency Disrupts the Hepatocyte E-Cadherin/beta-Catenin Complex and Induces Cell Death in Liver Ischemia/Reperfusion Injury. ADAM, IRI
47  2020 Tissue inhibitor of metalloproteinase proteins inhibit teratoma growth in mice transplanted with pluripotent stem cells. MMP, NP, NSC-CM, PSCs
48  2020 Tissue Inhibitor of Metalloproteinases-2 Mediates Kidney Injury during Sepsis. AKI, S-AKI
49  2020 TLR4-mediated hippocampal MMP/TIMP imbalance contributes to the aggravation of perioperative neurocognitive disorder in db/db mice. BBB, IL, MMP, PND, POD, TLR4, TNF
50  2020 Value of metalloproteinases in predicting COPD in heavy urban smokers. ---
51  2020 [A Study on the Role and Mechanism of Fenofibrate in Mice Renal Fibrosis Induced by Unilateral Ureteral Obstruction]. alpha-SMA, MMP, RT, TGF
52  2020 [Effect of tissue inhibitor of metalloproteinase-1 and 2 siRNA on the expression of smad2/3/4 protein in hepatic stellate cells]. alpha-SMA, ANOVA, HSC
53  2019 11,12 and 14,15 epoxyeicosatrienoic acid rescue deteriorated wound healing in ischemia. EETs, MMP, SD
54  2019 Agonism of GPR39 displays protective effects against advanced glycation end-product (AGE)-induced degradation of extracellular matrix in human SW1353 cells. AGE, AGEs, ECM, MAPK, MMP, NF-kappaB
55  2019 Association between tissue inhibitor of metalloproteinase (TIMP) genetic polymorphisms and primary ovarian insufficiency (POI). MMPs, POI
56  2019 Attenuation of UVB-Induced Photo-Aging by Polyphenolic-Rich Spatholobus Suberectus Stem Extract Via Modulation of MAPK/AP-1/MMPs Signaling in Human Keratinocytes. AP-1, CI, COL1A1, ELN, HAS2, MAP, MAPKs, MMPs, NF-kappaB, ROS, SS, SS, UV
57  2019 Author Correction: Semen levels of matrix metalloproteinase (MMP) and tissue inhibitor of metalloproteinases (TIMP) protein families members in men with high and low sperm DNA fragmentation. MMP
58  2019 Brain natriuretic peptide mitigates TIMP2 induction and reinstates extracellular matrix catabolic activity via GSK3beta inhibition in glomerular podocytes exposed to a profibrogenic milieu. BNP, ECM, GSK, TGF
59  2019 Chemerin acts via CMKLR1 and GPR1 to stimulate migration and invasion of gastric cancer cells: putative role of decreased TIMP-1 and TIMP-2. CMKLR1, GPR1, SIDLS
60  2019 Chondroprotective effect of curcumin and lecithin complex in human chondrocytes stimulated by IL-1beta via an anti-inflammatory mechanism. COX-2, HA, IL, iNOS, NF, NO, PG, PGE2, TNF
61  2019 Correlation between MMP and TIMP levels and elastic moduli of ascending thoracic aortic aneurysms. ATAA
62  2019 Effect of doxycyline in chronic obstructive pulmonary disease - An exploratory study. BMI, CAT, COPD, GSH-Px, ICS, LPO, MMP, SAMA, SGRQ, TAO, TOS
63  2019 Effects of Sacubitril/Valsartan on Biomarkers of Extracellular Matrix Regulation in PatientsWith HFrEF. ECM, Gal-3, HF, MMP, PIIINP, PINP, sST2
64  2019 Engineering of TIMP-3 as a LAP-fusion protein for targeting to sites of inflammation. LAP
65  2019 Evaluation of Local Injection of Bevacizumab against Triple-Negative Breast Cancer Xenograft Tumors. BVZ, DLL4, I.V, MMP, PPI, TNBC, TNF, VEGF-A, VEGFR
66  2019 Exogenous H2S mitigates myocardial fibrosis in diabetic rats through suppression of the canonical Wnt pathway. DM, FBG, MMP, SMAD3, TGF
67  2019 Expression of Matrix Metalloproteinase-2, Tissue Inhibitor of Matrix Metalloproteinase-2 and CD147 in the Traditional Chinese Medicine "Compound T11" for Treatment of Chronic Liver Injury. LT, MMP, SMA, TCM
68  2019 Expression of N-Acetylglucosaminyltransferase III Promotes Trophoblast Invasion and Migration in Early Human Placenta. MMP
69  2019 Flow cytometric analysis of the leukocyte landscape during bleomycin-induced lung injury and fibrosis in the rat. BAL
70  2019 Fructose-1,6-bisphosphate prevents pulmonary fibrosis by regulating extracellular matrix deposition and inducing phenotype reversal of lung myofibroblasts. ECM, FBP, FLF, MMP, PF
71  2019 Functional disparities within the TIMP family in cancer: hints from molecular divergence. ---
72  2019 Functional recovery in photo-damaged human dermal fibroblasts by human adipose-derived stem cell extracellular vesicles. EVs, hASCs, HDFs, miRNA, MMPs, NTA, TEM, TGF, UVB
73  2019 Gexia-Zhuyu Decoction Attenuates Carbon Tetrachloride-Induced Liver Fibrosis in Mice Partly via Liver Angiogenesis Mediated by Myeloid Cells. GFP, GZD, MMP, VEGF
74  2019 Glycine tomentella hayata extract and its ingredient daidzin ameliorate cyclophosphamide-induced hemorrhagic cystitis and oxidative stress through the action of antioxidation, anti-fibrosis, and anti-inflammation. 3-NT, CYP, ITG, MMP, NOX4, ROS
75  2019 Hepatocyte Growth Factor Facilitates Esophageal Mucosal Repair and Inhibits the Submucosal Fibrosis in a Rat Model of Esophageal Ulcer. HGF, MMP
76  2019 High glucose environment induces M1 macrophage polarization that impairs keratinocyte migration via TNF-alpha: An important mechanism to delay the diabetic wound healing. CM, TNF-alpha
77  2019 High serum levels of tissue inhibitor of matrix metalloproteinase-1 during the first week of a malignant middle cerebral artery infarction in non-surviving patients. GCS, MMCAI, MMP
78  2019 Histology and molecular pathology of iliotibial tract contracture in patients with gluteal muscle contracture. MMP-1
79  2019 IL-17 and TNF-alpha co-operation contributes to the proinflammatory response of hepatic stellate cells. HSCs, IL, MCP-1, MMP, PBMC, PHA, TNF
80  2019 Imbalances in tissue inhibitors of metalloproteinases differentiate choroidal neovascularization from geographic atrophy. AMD, GA, MMPs
81  2019 Immune biomarkers in maternal plasma to identify histologic chorioamnionitis in women with preterm labor. CRP, HCA, IGFBP-2, IL, MMP
82  2019 Infiltrating CCR2+ monocytes and their progenies, fibrocytes, contribute to colon fibrosis by inhibiting collagen degradation through the production of TIMP-1. BM, CCR2, EGFP, IBD
83  2019 Inotilone from Inonotus linteus suppresses lung cancer metastasis in vitro and in vivo through ROS-mediated PI3K/AKT/MAPK signaling pathways. COX, FAK, IL, iNOS, MAPK, MMP, NF, PI3K, TNF-alpha
84  2019 Insulin-like growth factor binding protein related protein 1 knockdown attenuates hepatic fibrosis via the regulation of MMPs/TIMPs in mice. alpha-SMA, ECM, Hh, IGFBPrP1, MMP, Shh, TAA, TGF-beta1
85  2019 Lanthanum Chloride Impairs the Blood-Brain Barrier Integrity by Reduction of Junctional Proteins and Upregulation of MMP-9 in Rats. BBB, MMPs
86  2019 Matrix Metalloproteinase 9 as a Predictor of Coronary Atherosclerotic Plaque Instability in Stable Coronary Heart Disease Patients with Elevated Lipoprotein(a) Levels. apoB100, CHD, hs-CRP, IVUS, MMPs
87  2019 Metalloprotease inhibitor TIMP proteins control FGF-2 bioavailability and regulate skeletal growth. ---
88  2019 MicroRNA-29a Exhibited Pro-Angiogenic and Anti-Fibrotic Features to Intensify Human Umbilical Cord Mesenchymal Stem Cells-Renovated Perfusion Recovery and Preventing against Fibrosis from Skeletal Muscle Ischemic Injury. BPVC, miR-29a, MMPs
89  2019 MMP targeting in the battle for vision: Recent developments and future prospects in the treatment of diabetic retinopathy. DR, MMPs
90  2019 Morus alba Stem Extract Suppresses Matrix Metalloproteinases (MMP)-1, MMP-9, and Tissue Inhibitors of Metalloproteinase (TIMP)-1 Expression via Inhibition of IkappaBalpha Degradation Induced by Porphyromonas gingivalis LPS Signal in THP-1 Cells. IkappaBalpha, LPS, MMP, MSE
91  2019 Noninvasive Liver Fibrosis Tests in Patients with Nonalcoholic Fatty Liver Disease: An External Validation Cohort. APRI, AUROC, ELF, FIB-4, HA, NAFLD, NPV, PIIINP, PPV
92  2019 Novel Biomarkers for the Precisive Diagnosis and Activity Classification of Takayasu Arteritis. CA, ELISA, IGFBP, TA
93  2019 Oxaliplatin aggravates hepatic oxidative stress, inflammation and fibrosis in a non‑alcoholic fatty liver disease mouse model. IFN, IL, MDA, NAFLD, OXA, ROS, TGF, TNF
94  2019 Persistently high circulating tissue inhibitor of matrix metalloproteinase-1 levels in non-survivor brain trauma injury patients. MMP
95  2019 Protective Effects and Mechanisms of N-Phenethyl Caffeamide from UVA-Induced Skin Damage in Human Epidermal Keratinocytes through Nrf2/HO-1 Regulation. 8-OHdG, ERK, HO-1, IL-6, iNOS, JNK, MMP, NO, Nrf2, ROS, UV
96  2019 Protective Effects of Activated Myofibroblasts in the Pressure-Overloaded Myocardium Are Mediated Through Smad-Dependent Activation of a Matrix-Preserving Program. MMP, TGF
97  2019 Quercetin suppresses the proliferation and metastasis of metastatic osteosarcoma cells by inhibiting parathyroid hormone receptor 1. MMP, PTHR1
98  2019 Recombinant Treponema pallidum protein Tp47 induces angiogenesis by modulating the matrix metalloproteinase/tissue inhibitor of metalloproteinase balance in endothelial cells. HUVECs, MMP
99  2019 Salivary levels of MPO, MMP-8 and TIMP-1 are associated with gingival inflammation response patterns during experimental gingivitis. MMP, MPO, NE, suPAR
100  2019 Semen levels of matrix metalloproteinase (MMP) and tissue inhibitor of metallorproteinases (TIMP) protein families members in men with high and low sperm DNA fragmentation. MMP, MMPs, ROS, TIMPs