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Abbreviation : TPs
Long Form : therapeutic proteins
No. Year Title Co-occurring Abbreviation
2020 Antibodies for the Treatment of Brain Metastases, a Dream or a Reality? AMT, BBB, BM, CNS, mAb, OS, RMT, sMDs
2020 Proteolysis and Oxidation of Therapeutic Proteins After Intradermal or Subcutaneous Administration. ID, PK, s.c
2019 Effect of Iron Oxide Nanoparticles on the Oxidation and Secondary Structure of Growth Hormone. IONPs, rGH
2018 High-Throughput In-Use and Stress Size Stability Screening of Protein Therapeutics Using Algorithm-Driven Dynamic Light Scattering. DLS
2017 Interactions Between Therapeutic Proteins and Small Molecules: The Shared Role of Perpetrators and Victims. DDIs, sMDs
2016 A Bottom-Up Whole-Body Physiologically Based Pharmacokinetic Model to Mechanistically Predict Tissue Distribution and the Rate of Subcutaneous Absorption of Therapeutic Proteins. PBPK, s.c
2016 Microfluidic Platform for Assessment of Therapeutic Proteins Using Molecular Charge Modulation Enhanced Electrokinetic Concentration Assays. EC, MCM, TPR
2015 Challenges and considerations for development of therapeutic proteins in pediatric patients. PK
2013 A physiologically based pharmacokinetic modeling approach to predict disease-drug interactions: suppression of CYP3A by IL-6. AUC, BMT, IL-6, RA, TP-DDIs
10  2013 Are hepatic impairment studies necessary for therapeutic proteins? ---
11  2013 Critical review of preclinical approaches to investigate cytochrome p450-mediated therapeutic protein drug-drug interactions and recommendations for best practices: a white paper. DDIs
12  2013 Integration of models and experimentation to optimise the production of potential biotherapeutics. ---
13  2011 AAPS workshop report: strategies to address therapeutic protein-drug interactions during clinical development. BLAs, NDAs, PD, PK, TP-DI
14  2011 How current understanding of clearance mechanisms and pharmacodynamics of therapeutic proteins can be applied for evaluation of their drug-drug interaction potential. DDIs
15  2010 CYP-mediated therapeutic protein-drug interactions: clinical findings, proposed mechanisms and regulatory implications. ---