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Abbreviation : TrkB
Long Form : tyrosine kinase B
No. Year Title Co-occurring Abbreviation
2020 Fabrication and characterization of zein/lactoferrin composite nanoparticles for encapsulating 7,8-dihydroxyflavone: Enhancement of stability, water solubility and bioaccessibility. 7,8-DHF, BDNF, LF
2019 3beta,23,28-Trihydroxy-12-oleanene 3beta-Caffeate from Desmodium sambuense-Induced Neurogenesis in PC12 Cells Mediated by ER Stress and BDNF-TrkB Signaling Pathways. ER, ERK, IGF-1R, MEK, PI3K
2019 Benefit effect of REM-sleep deprivation on memory impairment induced by intensive exercise in male wistar rats: with respect to hippocampal BDNF and TrkB. BDNF, PFC
2019 Brain-derived neurotrophic factor induces thioredoxin-1 expression through TrkB/Akt/CREB pathway in SH-SY5Y cells. BDNF, CREB, PI3K, Trx-1
2019 Centella asiatica (Gotu kola) ethanol extract up-regulates hippocampal brain-derived neurotrophic factor (BDNF), tyrosine kinase B (TrkB) and extracellular signal-regulated protein kinase 1/2 (ERK1/2) signaling in chronic electrical stress model in rats. BDNF, RT-PCR
2019 Consuming egg yolk decreases body weight and increases serum HDL and brain expression of TrkB in male SD rats. EW, EY, HDL
2019 Dexmedetomidine ameliorates memory impairment in sleep-deprived mice. BDNF, GFAP, IkappaBalpha, IL, NF-kappaB, TNF-alpha
2019 Downregulated hippocampal expression of brain derived neurotrophic factor and tyrosine kinase B in a rat model of comorbid epilepsy and depression. BDNF, UCMS
2019 Effect of social isolation stress on saliva BDNF in rat. BDNF, ELISA
10  2019 Ginsenoside Rb1 pretreatment reverses hippocampal changes in BDNF/TrkB mRNA and protein in rats subjected to acute immobilization stress. ACTH, BDNF, CORT
11  2019 Licorisoflavan A Exerts Antidepressant-Like Effect in Mice: Involvement of BDNF-TrkB Pathway and AMPA Receptors. AMPA, BDNF, CMS, CREB, eEF2, ERK, FST, GluR1, mTOR, OFT, p70S6K, PSD-95, SPT, TST
12  2019 Neuron-targeted caveolin-1 improves neuromuscular function and extends survival in SOD1G93A mice. ALS, Cav-1, MLRs, NTR
13  2019 Peripheral blood brain-derived neurotrophic factor level and tyrosine kinase B expression on T lymphocytes in systemic lupus erythematosus: Implications for systemic involvement. BDNF, ELISA, SLE
14  2019 Pharmacotherapy with sertraline rescues brain development and behavior in a mouse model of CDKL5 deficiency disorder. BDNF, CDKL5, KO, SSRI
15  2019 The Low Molecular Weight Brain-derived Neurotrophic Factor Mimetics with Antidepressant-like Activity. BDNF
16  2019 Treadmill exercise ameliorates nicotine withdrawal-induced symptoms. 5-HT, BrdU, TPH
17  2019 [Effects of huayu tongluo moxibustion on learning and memory ability and the hippocampal BDNF/TrkB expressions in the rats of vascular dementia]. 2VO, BDNF, EGFP, EPCs, NSCs, VD
18  2018 Dexmedetomidine mitigates sevoflurane-induced cell cycle arrest in hippocampus. BDNF, DEX
19  2018 Diosgenin improves functional recovery from sciatic crushed nerve injury in rats. BDNF, COX-2, iNOS, PVN, SFI, vlPAG
20  2018 Histone acetylation of oligodendrocytes protects against white matter injury induced by inflammation and hypoxia-ischemia through activation of BDNF-TrkB signaling pathway in neonatal rats. AH3, BDNF, BrdU, HI, WMI
21  2018 Late starting treadmill exercise improves spatial leaning ability through suppressing CREP/BDNF/TrkB signaling pathway following traumatic brain injury in rats. BDNF, CREB, TBI
22  2018 Multimodal early-life stress induces biological changes associated to psychopathologies. ELS
23  2018 Prenatal Deltamethrin Exposure-Induced Cognitive Impairment in Offspring Is Ameliorated by Memantine Through NMDAR/BDNF Signaling in Hippocampus. BDNF, MWM, NMDAR, pCREB
24  2018 Proliferative role of BDNF/TrkB signaling is associated with anoikis resistance in cervical cancer. AAT, BDNF, CC
25  2018 SKF83959 Has Protective Effects in the Scopolamine Model of Dementia. AD, BDNF
26  2018 Supramolecular Nanostructure Activates TrkB Receptor Signaling of Neuronal Cells by Mimicking Brain-Derived Neurotrophic Factor. BDNF, CNS, PA
27  2018 The antidepressant fluoxetine acts on energy balance and leptin sensitivity via BDNF. BDNF, FLX
28  2018 The receptor tyrosine kinase TrkB signals without dimerization at the plasma membrane. BDNF, RTKs
29  2018 Treadmill exercise with bone marrow stromal cells transplantation facilitates neuroprotective effect through BDNF-ERK1/2 pathway in spinal cord injury rats. BDNF, BMSCs, SCI
30  2017 Age-dependent differences of treadmill exercise on spatial learning ability between young- and adult-age rats. BDNF
31  2017 BDNF-TrkB controls cocaine-induced dendritic spines in rodent nucleus accumbens dissociated from increases in addictive behaviors. BDNF, NAcSh, PLC-gamma1
32  2017 Dexmedetomidine Oral Mucosa Patch for Sedation Suppresses Apoptosis in Hippocampus of Normal Rats. BDNF
33  2017 Epigenetic regulation by G9a/GLP complex ameliorates amyloid-beta 1-42 induced deficits in long-term plasticity and synaptic tagging/capture in hippocampal pyramidal neurons. AD, BDNF, LTP, oAbeta, STC
34  2017 Presynaptic Muscarinic Acetylcholine Receptors and TrkB Receptor Cooperate in the Elimination of Redundant Motor Nerve Terminals during Development. LAL
35  2017 Salivary Gland Derived BDNF Overexpression in Mice Exerts an Anxiolytic Effect. BDNF, GABA, GAD1, HA
36  2017 Treadmill exercise ameliorates social isolation-induced depression through neuronal generation in rat pups. 5-HT, BDNF, BrdU, TPH
37  2017 Treadmill exercise suppressed stress-induced dendritic spine elimination in mouse barrel cortex and improved working memory via BDNF/TrkB pathway. BDNF
38  2016 Activation of GABAB2 subunits alleviates chronic cerebral hypoperfusion-induced anxiety-like behaviours: A role for BDNF signalling and Kir3 channels. BDNF, NCAM
39  2016 Endothelial progenitor cells and neural progenitor cells synergistically protect cerebral endothelial cells from Hypoxia/reoxygenation-induced injury via activating the PI3K/Akt pathway. BDNF, ECs, EPCs, NPCs, PI3K, ROS, VEGF, VEGFR2
40  2016 Inhibition of TrkB limits development of the zebra finch song system. RA
41  2016 Long-Term Dietary Alpha-Linolenic Acid Supplement Alleviates Cognitive Impairment Correlate with Activating Hippocampal CREB Signaling in Natural Aging Rats. ALA, BDNF, CaMKIV, CREB, ERK, PKA, PUFA
42  2016 Maladaptive choices by defeated rats: link between rapid approach to social threat and escalated cocaine self-administration. BDNF, CRF, PCA
43  2016 Music application alleviates short-term memory impairments through increasing cell proliferation in the hippocampus of valproic acid-induced autistic rat pups. BDNF
44  2016 Neuroprotective Effects of Bone Marrow Stromal Cell Transplantation in Combination With Treadmill Exercise Following Traumatic Brain Injury. BDNF, BMSCs, TBI
45  2016 Postnatal Treadmill Exercise Alleviates Prenatal Stress-Induced Anxiety in Offspring Rats by Enhancing Cell Proliferation Through 5-Hydroxytryptamine 1A Receptor Activation. 5HT1A, BDNF
46  2016 Prenatal Cocaine Exposure Alters BDNF-TrkB Signaling in the Embryonic and Adult Brain. BDNF
47  2016 Reversal Learning Deficits Associated with Increased Frontal Cortical Brain-Derived Neurotrophic Factor Tyrosine Kinase B Signaling in a Prenatal Cocaine Exposure Mouse Model. BDNF
48  2016 Treadmill exercise alleviates impairment of cognitive function by enhancing hippocampal neuroplasticity in the high-fat diet-induced obese mice. BDNF
49  2015 Expression of Brain-derived Neurotrophic Factor and Tyrosine Kinase B in Cerebellum of Poststroke Depression Rat Model. BDNF, IR, PSD, RT-PCR, UCMS
50  2015 Pituitary Adenylate Cyclase-Activating Peptide in the Central Amygdala Causes Anorexia and Body Weight Loss via the Melanocortin and the TrkB Systems. CeA, PACAP
51  2015 The standardized Lycium chinense fruit extract protects against Alzheimer's disease in 3xTg-AD mice. AD, BDNF, LFE
52  2015 Treadmill exercise alleviates stress-induced impairment of social interaction through 5-hydroxytryptamine 1A receptor activation in rats. BDNF, CREB
53  2015 Treadmill exercise improves short-term memory by enhancing hippocampal cell proliferation in quinolinic acid-induced Huntington's disease rats. BDNF, BrdU, HD, QA
54  2014 Circadian modulation of memory and plasticity gene products in a diurnal species. BDNF, MWM
55  2014 Effect of glatiramer acetate on peripheral blood brain-derived neurotrophic factor and phosphorylated TrkB levels in relapsing-remitting multiple sclerosis. BDNF, GA
56  2014 Mice lacking TrkB in parvalbumin-positive cells exhibit sexually dimorphic behavioral phenotypes. BDNF, PV
57  2014 Treadmill exercise alleviates impairment of spatial learning ability through enhancing cell proliferation in the streptozotocin-induced Alzheimer's disease rats. BDNF, BrdU, i.c.v, STZ
58  2014 Treadmill exercise ameliorates disturbance of spatial learning ability in scopolamine-induced amnesia rats. BDNF, BrdU
59  2014 Treadmill exercise improves short-term memory by enhancing neurogenesis in amyloid beta-induced Alzheimer disease rats. Abeta25-35, BDNF, i.c.v
60  2014 Treadmill exercise improves spatial learning ability by enhancing brain-derived neurotrophic factor expression in the attention-deficit/hyperactivity disorder rats. ADHD, BDNF
61  2013 7,8-Dihydroxyflavone improves memory consolidation processes in rats and mice. 7,8-DHF, BDNF, CNS
62  2013 Dexmedetomidine ameliorates intracerebral hemorrhage-induced memory impairment by inhibiting apoptosis and enhancing brain-derived neurotrophic factor expression in the rat hippocampus. BDNF, ICH, TUNEL
63  2013 Effect of treadmill running on the expression of genes that are involved in neuronal differentiation in the hippocampus of adult male rats. BDNF, REST
64  2013 Exercise facilitates the action of dietary DHA on functional recovery after brain trauma. 4-HHE, ACOX1, BDNF, DHA, iPLA2, mFPI, STX3, TBI
65  2013 Inactivation of JAK2/STAT3 signaling axis and downregulation of M1 mAChR cause cognitive impairment in klotho mutant mice, a genetic model of aging. ACh, AChE, ChAT, JAK2, LTP, M1 mAChR, McN, STAT3
66  2013 Increased expression of neurotrophin 4 following focal cerebral ischemia in adult rat brain with treadmill exercise. BDNF, NT-4
67  2013 Isoflurane Induces Transient Anterograde Amnesia through Suppression of Brain-Derived Neurotrophic Factor in Hippocampus. BDNF
68  2013 Molecular mechanisms of environmental enrichment: impairments in Akt/GSK3beta, neurotrophin-3 and CREB signaling. BDNF, CREB, FAD, GSK3beta, IGF-1, NGF, NMDA, NT-3
69  2013 Postnatal expression of TrkB receptor in rat vestibular nuclear neurons responsive to horizontal and vertical linear accelerations. ---
70  2013 Reduced social interaction, behavioural flexibility and BDNF signalling in the BTBR T+ tf/J strain, a mouse model of autism. BDNF, BTBR
71  2013 Serotonin-kynurenine hypothesis of depression: historical overview and recent developments. KYN, NAS, Trp
72  2013 Suppression of choriocarcinoma invasion and metastasis following blockade of BDNF/TrkB signaling. BDNF, SCID
73  2013 [Effects of ginsenoside Rb1 on the mRNA expression of tyrosine kinase B in the hippocampus of acute immobilization stress rats]. ACTH, CORT
74  2013 [Effects of shuyu ningxln recipe on the praxiology and the expressions of hippocampal BDNF and trkB of model rats with chronic stress-induced depression]. BDNF, SNR
75  2012 Anxiogenic-like effects of chronic cannabidiol administration in rats. BDNF, CBD, CER, CREB
76  2012 Association of brain-derived neurotrophic factor and tyrosine kinase B receptor in pregnancy. ADHD, BDNF, DHA, ELISA
77  2012 Electroacupuncture enhances motor recovery performance with brain-derived neurotrophic factor expression in rats with cerebral infarction. BDNF, EA
78  2012 Increased expression of TrkB and Capzb2 accompanies preserved cognitive status in early Alzheimer disease pathology. AD, BDNF
79  2012 Inhibition of uterine sarcoma cell growth through suppression of endogenous tyrosine kinase B signaling. BDNF
80  2012 Interaction between neurotrophin 4 and gonadotrophin in bovine oviducts. BOECs, ELISA, FSH, FSHR, LH, LHR, NT4, RT-PCR
81  2012 Peptide-mediated targeting of liposomes to TrkB receptor-expressing cells. PCL
82  2012 Suppression of hydatidiform molar growth by inhibiting endogenous brain-derived neurotrophic factor/tyrosine kinase B signaling. BDNF
83  2012 [Expression of trkB gene in the pulmonary tissue of rats with lung injury induced by cerebral ischemia]. BILI
84  2011 Brain-derived neurotrophic factor-tyrosine kinase B pathway mediates NMDA receptor NR2B subunit phosphorylation in the supraoptic nuclei following progressive dehydration. BDNF, SON, WD
85  2011 Brain-derived neurotrophic factor/tyrosine kinase B signaling regulates human trophoblast growth in an in vivo animal model of ectopic pregnancy. BDNF, EVTs
86  2011 Ethanol alters BDNF-induced Rho GTPase activation in axonal growth cones. BDNF, GTPases
87  2011 Impact of sound exposure and aging on brain-derived neurotrophic factor and tyrosine kinase B receptors levels in dorsal cochlear nucleus 80 days following sound exposure. ABR, BDNF, DCN, FBN, PTS
88  2011 Neural differentiation of brain-derived neurotrophic factor-expressing human umbilical cord blood-derived mesenchymal stem cells in culture via TrkB-mediated ERK and beta-catenin phosphorylation and following transplantation into the developing brain. BDNF, ERKs, hUCB-MSCs, MSCs
89  2011 Silent synapses in neuromuscular junction development. ACh, BDNF, PKC
90  2011 Tyrosine kinase B protein expression is reduced in the cerebellum of patients with bipolar disorder. BDNF
91  2010 Brain-derived neurotrophic factor redistribution in the dorsal root ganglia correlates with neuropathic pain inhibition after resiniferatoxin treatment. BDNF, DRG, RTX, VR1
92  2010 Curcumin produces neuroprotective effects via activating brain-derived neurotrophic factor/TrkB-dependent MAPK and PI-3K cascades in rodent cortical neurons. BDNF, CREB
93  2010 Detection of TrkB receptors distributed in cultured hippocampal neurons through bioconjugation between highly luminescent (quantum dot-neutravidin) and (biotinylated anti-TrkB antibody) on neurons by combined atomic force microscope and confocal laser scanning microscope. QD
94  2010 Effects of chronic forced swim stress on hippocampal brain-derived neutrophic factor (BDNF) and its receptor (TrkB) immunoreactive cells in juvenile and aged rats. BDNF, DG, FS
95  2010 Identification of a novel mutation in the NTF4 gene that causes primary open-angle glaucoma in a Chinese population. Leu113Ser, NT-4, POAG
96  2010 Increased BDNF levels and NTRK2 gene association suggest a disruption of BDNF/TrkB signaling in autism. BDNF, SNPs
97  2010 Modulators of cytoskeletal reorganization in CA1 hippocampal neurons show increased expression in patients at mid-stage Alzheimer's disease. AD, BB, BDNF
98  2009 Brain-derived neurotrophic factor modulation of Kv1.3 channel is disregulated by adaptor proteins Grb10 and nShc. BDNF, Grb10, HEK293, nShc, OB, SH2
99  2009 Brain-derived neurotrophic factor promotes implantation and subsequent placental development by stimulating trophoblast cell growth and survival. BDNF
100  2009 Energy-restricted pair-feeding normalizes low levels of brain-derived neurotrophic factor/tyrosine kinase B mRNA expression in the hippocampus, but not ventromedial hypothalamic nucleus, in diet-induced obese mice. BDNF, DIO, HF, LF, VMH