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Abbreviation : UTI
Long Form : urinary trypsin inhibitor
No. Year Title Co-occurring Abbreviation
2021 A Chondroitin Sulfate Chain of Urinary Trypsin Inhibitor Enhances Protease Inhibitory Activity of the Core Protein. ---
2020 Perioperation ulinastatin intervention protects liver function in hepatectomy: a systematic review of randomized controlled trials and meta-analysis. ALT, AST, IR, RCTs, TBIL
2020 Recombinant human ulinastatin improves immune dysfunction of dendritic cells in septic mice by inhibiting endoplasmic reticulum stress-related apoptosis. CLP, DCs, ERS
2020 Serum bikunin isoforms in congenital disorders of glycosylation and linkeropathies. Bkn, CDG, CS
2020 Ulinastatin Inhibits the Proliferation, Invasion and Phenotypic Switching of PDGF-BB-Induced VSMCs via Akt/eNOS/NO/cGMP Signaling Pathway. cGMP, VSMCs
2019 MMP-2 and MMP-9 gene polymorphisms act as biological indicators for ulinastatin efficacy in patients with severe acute pancreatitis. GMDR, MMP-2, MMP-9, PCR-RFLP, SAP
2019 Ulinastatin ameliorates LPS‑induced pulmonary inflammation and injury by blocking the MAPK/NF‑kappaB signaling pathways in rats. ALI, BALF, IL, LPS, MPO
2018 Effect of ulinastatin on interleukins and pulmonary function in bypass patients: ameta-analysis of randomized controlled trials. IL-6, PMNE, TNF-alpha
2018 Endothelial Glycocalyx Layer: A Possible Therapeutic Target for Acute Lung Injury during Lung Resection. EGL, VATS
10  2018 Levels of Urinary Trypsin Inhibitor and Structure of Its Chondroitin Sulphate Moiety in Type 1 and Type 2 Diabetes. CS
11  2018 Neuroprotection of ulinastatin on transient cerebral ischemia via antioxidative mechanisms. 8-iso PGF2alpha, ARE, CA, mNSS, SOD
12  2018 The Protective Roles of Urinary Trypsin Inhibitor in Brain Injury Following Fat Embolism Syndrome in a Rat Model. BBB, FES
13  2018 Ulinastatin alleviates neurological deficiencies evoked by transient cerebral ischemia via improving autophagy, Nrf-2-ARE and apoptosis signals in hippocampus. CA, CPR, mNSS, TUNEL
14  2018 Ulinastatin Ameliorates Pulmonary Capillary Endothelial Permeability Induced by Sepsis Through Protection of Tight Junctions via Inhibition of TNF-alpha and Related Pathways. CLP, EB, ERKs, IkappaB, JNKs, LPS, MAPKs, p38 MAPKs, PMVECs, TJs
15  2017 Effect of ulinastatin combined with thymosin alpha1 on sepsis: A systematic review and meta-analysis of Chinese and Indian patients. APACHE, IL, Talpha1
16  2017 Effect of ulinastatin combined with thymosin alpha1 on sepsis: A systematic review and meta-analysis of Chinese and Indian patients. APACHE, IL, Talpha1
17  2017 Effect of urinary trypsin inhibitor on inflammatory cytokines and organ function in patients with cardiopulmonary bypass. AST, DB, IL-1beta, IL-6, IL-8, TB, TNF-alpha
18  2017 Effects of ulinastatin on global ischemia via brain pro-inflammation signal. CA, IL-1beta, IL-6, PICs, TNF-alpha
19  2017 Ulinastatin ameliorates tissue damage of severe acute pancreatitis through modulating regulatory T cells. MPO, SAP
20  2016 Blockade of NF-kappaB and MAPK pathways by ulinastatin attenuates wear particle-stimulated osteoclast differentiation invitro and invivo. BMD, BV/TV, IL-6, LPS, MMP-9, NF-kappaB, PAMPs, PMMA, RANK, Tb.N, Tb.Sp, Tb.Th, TNF-alpha
21  2016 Ulinastatin administration is associated with a lower incidence of acute kidney injury after cardiac surgery: a propensity score matched study. AKI, CPB
22  2015 Lack of Efficacy of Ulinastatin Therapy During Cardiopulmonary Bypass Surgery. CPB
23  2015 Urinary Trypsin Inhibitor Attenuates Acute Lung Injury by Improving Endothelial Progenitor Cells Functions. ALI, OA
24  2015 Urinary trypsin inhibitor attenuates LPS-induced endothelial barrier dysfunction by upregulation of vascular endothelial-cadherin expression. ECIS, HUVECs, LPS, mAb, VE-cadherin
25  2015 Urinary trypsin inhibitor levels are reduced in cerebrospinal fluid of multiple sclerosis and neuromyelitis optica patients during relapse. CSF, MS, NMO
26  2015 Urinary Trypsin Inhibitor Reduced Inflammation Response Induced by Hyperlipidemia. miR-181b, N/M, NT
27  2014 Cytoprotective effects of urinary trypsin inhibitor on astrocytes injured by sustained compression. LDH, TBI
28  2013 Development of a method for urine bikunin/urinary trypsin inhibitor (UTI) quantitation and structural characterization: Application to type 1 and type 2 diabetes. ---
29  2013 Does urinary trypsin inhibitor have a role in acute lung injury induced by pulmonary contusion: a basic research in a model of rats. BALF
30  2013 Effects of pulmonary artery perfusion with urinary trypsin inhibitor as a lung protective strategy under hypothermic low-flow cardiopulmonary bypass in an infant piglet model. CPB, DHLF, ELISA, EMSA, NF-kappaB, TNF-alpha, MPO, MDA and IL-10
31  2013 Intra-amniotic administration of urinary trypsin inhibitor preserves intestinal contractility in meconium induced intestinal damage in chick embryos with gastroschisis. ---
32  2013 Protective effects of urinary trypsin inhibitor on vascular permeability following subarachnoid hemorrhage in a rat model. IL-6, MDA, MPO, MRI, SAH, TNF-alpha
33  2013 Ulinastatin exerts synergistic effects with taxotere and inhibits invasion and metastasis of breast cancer by blocking angiogenesis and the epithelial-mesenchymal transition. EMT, TXT
34  2013 Urinary trypsin inhibitor attenuates lipopolysaccharide-induced neutrophil activation. ELISA, EMSA, IL, LPS, NF-kappaB, TNF-alpha
35  2013 Urine bikunin as a marker of renal impairment in Fabry's disease. ---
36  2012 Determination of urinary trypsin inhibitor provides insight into postoperative complications in patients following esophagectomy. PMN-E
37  2012 Initial experience using Sivelestat to manage preterm labor with a bulging fetal membrane in pregnant women. IL
38  2012 Kinetics and thermodynamics of 1-anilino-8-naphthalene sulfonate interactions with Urinary Trypsin Inhibitor. ANS
39  2012 Urinary trypsin inhibitor attenuates liver enzyme elevation after liver resection. ALT, AST
40  2012 Urinary trypsin inhibitor reduced inflammatory response after stent injury in minipig. ---
41  2012 Urinary trypsin inhibitor reduced neointimal hyperplasia induced by systemic inflammation after balloon injury in rabbits. LPS
42  2011 Affinity purification of urinary trypsin inhibitor from human urine. ---
43  2011 Effects of urinary trypsin inhibitor on lipopolysaccharide-induced acute lung injury in rabbits. BALF, LPS
44  2011 Preventive effect of urinary trypsin inhibitor on the development of liver fibrosis in mice. HA, KO, TA, TGF-beta
45  2011 Urinary trypsin inhibitor attenuates lipopolysaccharide-induced acute lung injury by blocking the activation of p38 mitogen-activated protein kinase. ALI, IL, LPS, MAPK, TNF
46  2011 Urinary trypsin inhibitor attenuates seawater-induced acute lung injury by influencing the activities of nuclear factor-B and its related inflammatory mediators. NE, NF-kappaB, SWD-ALI
47  2011 [Effect of urinary trypsin inhibitor on DNA genotyping in urine samples]. ---
48  2010 Effect of urinary trypsin inhibitor on preterm labor with high granulocyte elastase concentration in cervical secretions. ---
49  2010 Prenatal treatment of meconium peritonitis with urinary trypsin inhibitor. ---
50  2010 Protective effect of urinary trypsin inhibitor on the development of radiation-induced lung fibrosis in mice. ---
51  2010 Serine protease inhibitors suppress pancreatic endogenous proteases and modulate bacterial neutral proteases. ---
52  2010 Urinary trypsin inhibitor as a therapeutic option for endotoxin-related inflammatory disorders. DIC
53  2010 Urinary trypsin inhibitor suppresses excessive generation of superoxide anion radical, systemic inflammation, oxidative stress, and endothelial injury in endotoxemic rats. HMGB1, IL, LPS, sICAM-1, TNF
54  2010 Urinary trypsin inhibitor suppresses excessive superoxide anion radical generation in blood, oxidative stress, early inflammation, and endothelial injury in forebrain ischemia/reperfusion rats. FBI/R, HMGB1, ICAM-1
55  2009 Clinical and prognostic significance of urinary trypsin inhibitor in patients with hepatocellular carcinoma after hepatectomy. HCC
56  2009 Impaired liver regeneration with humoral and genetic disturbances in urinary trypsin inhibitor-deficient mice. BrdU, IL-6, LR, MCP-1, MIP-1beta, TNF-alpha
57  2009 Protective role of urinary trypsin inhibitor in lung expression of proinflammatory cytokines accompanied by lethal liver injury in mice. ---
58  2009 Urinary trypsin inhibitor attenuates hepatic ischemia-reperfusion injury by reducing nuclear factor-kappa B activation. I/R, NF-kappaB
59  2009 Urinary trypsin inhibitor protects against liver injury and coagulation pathway dysregulation induced by lipopolysaccharide/D-galactosamine in mice. IFN, TNF, WT
60  2009 Urinary trypsin inhibitor suppresses migration of malignant mesothelioma. PDGF-betabetaR, PDGF-D
61  2009 Urinary trypsin inhibitors afford cardioprotective effects through activation of PI3K-Akt and ERK signal transduction and inhibition of p38 MAPK and JNK. I/R, LAD, PI3K
62  2008 Protective effects of urinary trypsin inhibitor on systemic inflammatory response induced by lipopolysaccharide. DIC
63  2008 Role of serum-derived hyaluronan-associated protein-hyaluronan complex in ovarian cancer. HA, SHAP
64  2008 Urinary trypsin inhibitor ameliorates renal tissue oxygenation after ischemic reperfusion in rats. EPR, NS
65  2008 Urinary trypsin inhibitor improves viability of the liver in brain-dead rats. CINC, HTF
66  2008 Urinary trypsin inhibitor treatment ameliorates acute lung and liver injury resulting from sepsis in a rat model. AST, CLP, HR, IL-10, iNOS, MAP, MDA, SOD, TNF-alpha
67  2008 [Protective effect of urinary trypsin inhibitor on injury after intestinal ischemia-reperfusion: experiment with rats]. BT, I-FABP, MDA, MPO, NO, SO, SOD, TNF-alpha
68  2007 Insufficient production of urinary trypsin inhibitor for neutrophil elastase release after cardiac arrest. NE, ROSC
69  2007 pH induces thermal unfolding of UTI: an implication of reversible and irreversible mechanism based on the analysis of thermal stability, thermodynamic, conformational characterization. CD, RCL
70  2007 The activation of neutrophil elastase-mediated fibrinolysis is not sufficient to overcome the fibrinolytic shutdown of disseminated intravascular coagulation associated with systemic inflammation. DIC, PAI-1, SIRS
71  2007 Urinary trypsin inhibitor reduces inflammatory response in kidney induced by lipopolysaccharide. CINC-1, LPS, MPO, TNF-alpha
72  2006 Diversity in the degree of sulfation and chain length of the glycosaminoglycan moiety of urinary trypsin inhibitor isomers. ---
73  2006 Urinary trypsin inhibitor present in fetal urine prevents intraamniotic meconium-induced intestinal damage in gastroschisis. ---
74  2005 Antioxidative role of urinary trypsin inhibitor in acute lung injury induced by lipopolysaccharide. LPS, WT
75  2005 Beta-2-glycoprotein I and urinary trypsin inhibitor levels in the plasma of pregnant and postpartum women. Anx
76  2005 Development of an ELISA test for determination of the urinary trypsin inhibitor: analytical performance and applications. ELISA
77  2005 Effect of Ulinastatin, a human urinary trypsin inhibitor, on the oleic acid-induced acute lung injury in rats via the inhibition of activated leukocytes. ARDS, NM, OA, TNF
78  2005 Inhibition of lipopolysaccharide-induced tissue factor expression in monocytes by urinary trypsin inhibitor in vitro and in vivo. AP-1, DIC, Egr-1, ERK, LPS, NF-kappaB, TF
79  2005 Neutrophil-mediated inflammation in respiratory syncytial viral bronchiolitis. NE, RSV
80  2005 Protective role of urinary trypsin inhibitor in acute lung injury induced by lipopolysaccharide. ICAM-1, LPS, WT
81  2005 Urinary trypsin inhibitor suppresses surgical stress-facilitated lung metastasis of murine colon 26-L5 carcinoma cells. MMP-9
82  2004 Plasma and urine levels of urinary trypsin inhibitor in patients with chronic liver diseases and hepatocellular carcinoma. CH, HCC, LC
83  2004 Proinflammatory cytokines up-regulate synthesis and secretion of urinary trypsin inhibitor in human hepatoma HepG2 cells. IL-1beta, IL-6, RT-PCR, TNF-alpha
84  2004 Urinary trypsin inhibitor protects against systemic inflammation induced by lipopolysaccharide. KC, LPS, MCP, WT
85  2004 Urinary trypsin inhibitor reduces LPS-induced hypotension by suppressing tumor necrosis factor-alpha production through inhibition of Egr-1 expression. Egr-1, iNOS, LPS, TNF
86  2003 Amiloride and urinary trypsin inhibitor inhibit urothelial cancer invasion. uPA
87  2003 Combination assay of urinary free L-fucose and trypsin inhibitor may be useful indicators of disease activity in patients with hematologic malignancies. ANLL, MDS, MPD, U-FC
88  2003 Effect of urinary trypsin inhibitor on potassium currents: fetus modulates membrane excitability by production of UTI. ---
89  2003 Increased serum concentration of urinary trypsin inhibitor with asthma exacerbation. NE
90  2003 Neuroprotective effect of urinary trypsin inhibitor against focal cerebral ischemia-reperfusion injury in rats. ---
91  2003 Protective effect of urinary trypsin inhibitor on myocardial mitochondria during hemorrhagic shock and reperfusion. ATP, Lac, PCr, PP, Pyr
92  2003 Significant elevation of urinary trypsin inhibitor in patients with brain contusion--a preliminary report. ---
93  2003 Urinary trypsin inhibitor improves peripheral microcirculation and bronchospasm associated with systemic anaphylaxis in rabbits in vivo. CVP, HR, MAP
94  2003 [Changes of urinary tripsin inhibitor in blood and urine, as well as serum cytokines in living related liver transplantation]. IL, PMN-E, POD
95  2002 Effects of urinary trypsin inhibitor in patients at risk for premature labor with a bulging fetal membrane. ---
96  2002 Plasma and urine levels of urinary trypsin inhibitor in patients with acute and fulminant hepatitis. AH, ASH, FH, PLG, PT
97  2002 Protective effects of urinary trypsin inhibitor (UTI) on hepatic microvasculature in hypotensive brain-dead rats. CINC, HTF, ICAM, MAP, TNF
98  2002 Suppression of urokinase expression and tumor metastasis by bikunin overexpression [mini-review]. uPA
99  2002 Urinary trypsin inhibitor levels in the urine of patients with haematological malignancies. ---
100  2001 Calcium-induced changes in chondroitin sulfate chains of urinary trypsin inhibitor. ---