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Abbreviation : VA
Long Form : Verrucarin A
No. Year Title Co-occurring Abbreviation
2014 Regulation of IL-8 promoter activity by verrucarin A in human monocytic THP-1 cells. CEBP, DON, IL, NF-kappaB, OA, TNF
2014 Verrucarin A alters cell-cycle regulatory proteins and induces apoptosis through reactive oxygen species-dependent p38MAPK activation in the human breast cancer cell line MCF-7. ROS
2014 Verrucarin A induces apoptosis through ROS-mediated EGFR/MAPK/Akt signaling pathways in MDA-MB-231 breast cancer cells. ROS
2013 Combined treatment with verrucarin A and tumor necrosis factor-alpha sensitizes apoptosis by overexpression of nuclear factor-kappaB-mediated Fas. NF-kappaB, TNF-alpha
2013 Verrucarin A enhances TRAIL-induced apoptosis via NF-kappaB-mediated Fas overexpression. m-IkappaB, NF, TRAIL, VA/TRAIL
2013 Verrucarin A sensitizes TRAIL-induced apoptosis via the upregulation of DR5 in an eIF2alpha/CHOP-dependent manner. CHOP, eIF2alpha, ER, ROS, TRAIL
2013 Verrucarin A, a protein synthesis inhibitor, induces growth inhibition and apoptosis in breast cancer cell lines MDA-MB-231 and T47D. ---
2012 Lack of a functional VHL gene product sensitizes renal cell carcinoma cells to the apoptotic effects of the protein synthesis inhibitor verrucarin A. ccRCC, VHL
2003 Modulation of lipopolysaccharide-induced proinflammatory cytokine production by satratoxins and other macrocyclic trichothecenes in the murine macrophage. ELISA, IL-6, iSF, PCR, RA, SG, SH, TNF-alpha