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Abbreviation : XBP1
Long Form : X-box binding protein 1
No. Year Title Co-occurring Abbreviation
2020 Age-dependent impairment of adipose-derived stem cells isolated from horses. ASCs, CXCR4, ER, GLUT4, IL-8, INSR, IRE1, Mfn1, TNF-alpha
2020 ANGEL2 is a member of the CCR4 family of deadenylases with 2',3'-cyclic phosphatase activity. ANGEL2, mRNA, tRNA, TRNT1
2020 Antagonistic relationship between the unfolded protein response and myocardin-driven transcription in smooth muscle. ATF6, DTT, ER, IRE1alpha, MRTFs, MYOCD, SMCs, TN, UPR
2020 Asperuloside exhibits a novel anti-leukemic activity by triggering ER stress-regulated apoptosis via targeting GRP78. AML, ASP, ATF6, CHOP, eIF2alpha, ER, GRP78, IP, p-IRE1, PERK
2020 Asymmetrical dimethylarginine induces dysfunction of insulin signal transduction via endoplasmic reticulum stress in the liver of diabetic rats. ADMA, CHOP, eIF2alpha, ERS, GRP78, IR, IRS-1, PERK
2020 B Lymphocytes as Targets of the Immunomodulatory Properties of Human Amniotic Mesenchymal Stromal Cells. IRAK, IRF4, MSC, PRDM1
2020 Beneficial effect of ER stress preconditioning in protection against FFA-induced adipocyte inflammation via XBP1 in 3T3-L1 adipocytes. ER, FFAs, UPR
2020 Diphtheria toxoid nanoparticles improve learning and memory impairment in animal model of Alzheimer's disease. AD, DT, MWM, NP, RT-PCR
2020 Dysregulation in the Unfolded Protein Response in the FGR Rat Pancreas. AMPK, FGR, Perk, UPR
10  2020 Emulsified isoflurane protects beta cells against high glucose-induced apoptosis via inhibiting endoplasmic reticulum stress. ATF6, Bcl-2, eIF2alpha, EIso, ELISA, ERS, qRT-PCR, T2DM
11  2020 Endoplasmic Reticulum (ER) Stress Inhibitor or Antioxidant Treatments during Micromanipulation Can Inhibit Both ER and Oxidative Stresses in Porcine SCNT Embryos. ER, SCNT, TUDCA, Vit C
12  2020 Epigallocatechin-3-gallate (EGCG) protects the oocytes from methyl parathion-induced cytoplasmic deformities by suppressing oxidative and endoplasmic reticulum stress. 0.25muM, EGCG, GV, IVM, MP
13  2020 ER stress-related molecules induced by Hantaan virus infection in differentiated THP-1 cells. ATF6, CHOP, dTHP-1, ER stress, HTNV, IRE1, PERK, UPR
14  2020 Fibroblast Growth Factor 22 Inhibits ER Stress-Induced Apoptosis and Improves Recovery of Spinal Cord Injury. eIF2alpha, ER, FGF22, GAP43, GRP78, SCI
15  2020 Glycosylation deletion of hemagglutinin head in the H5 subtype avian influenza virus enhances its virulence in mammals by inducing endoplasmic reticulum stress. AIV, ER, HA, IRE1alpha, JNK
16  2020 Growth hormone activates X-box binding protein 1 in a sexually dimorphic manner through the extracellular signal-regulated protein kinase and CCAAT/enhancer-binding protein beta pathway in rat liver. ER, ERdj4, ERK, GH, IRE1alpha, PERK, STAT5B
17  2020 Hepatitis B Virus preS/S Truncation Mutant rtM204I/sW196* Increases Carcinogenesis through Deregulated HIF1A, MGST2, and TGFbi. ER, HBV, RT, TGFBI
18  2020 High-fat diet leads to elevated lipid accumulation and endoplasmic reticulum stress in oocytes, causing poor embryo development. ATF4, ATF6, ER, GRP78, HFD
19  2020 Hydrogen-rich saline protects intestinal epithelial tight junction barrier in rats with intestinal ischemia-reperfusion injury by inhibiting endoplasmic reticulum stress-induced apoptosis pathway. CHOP, ELISA, GRP78, HRS, I-FABP, IIRI, IL-1beta, SD, TJ, TNF-alpha, ZO-1
20  2020 IBD: Role of intestinal compartments in the mucosal immune response. CD, ER, FOXP3, HNE, LCM, LP, qRT-PCR, SE, UC
21  2020 Idebenone Protects against Spontaneous Chronic Murine Colitis by Alleviating Endoplasmic Reticulum Stress and Inflammatory Response. ATF6, CHOP, DAI, ER, UC
22  2020 Impact of post-ruminally infused macronutrients on bovine mammary gland expression of genes involved in fatty acid synthesis, energy metabolism, and protein synthesis measured in RNA isolated from milk fat. aa, ACC1, Eif2b5, ER, FA, FASN, ISR, mTORC1
23  2020 Intracellular XBP1-IL-24 axis dismantles cytotoxic unfolded protein response in the liver. CHOP, eIF2alpha, ER, IL-24
24  2020 IRE1A Stimulates Hepatocyte-Derived Extracellular Vesicles That Promote Inflammation in Mice With Steatohepatitis. EVs, NASH
25  2020 IRE1alpha regulates macrophage polarization, PD-L1 expression, and tumor survival. IL-6, PD-L1, RNA-Seq, UPR
26  2020 Kolaviron protects against nigrostriatal degeneration and gut oxidative damage in a stereotaxic rotenone model of Parkinson's disease. GI, KV, PD
27  2020 LncRNA TUG1 promotes tumor growth and metastasis of esophageal squamous cell carcinoma by regulating XBP1 via competitively binding to miR-498. ESCC, qRT-PCR, TUG1
28  2020 Long non-coding RNA LINC00299 knockdown inhibits ox-LDL-induced T/G HAVSMC injury by regulating miR-135a-5p/XBP1 axis in atherosclerosis. AS, LINC00299, lncRNA, miR-135a-5p, MMP9, MTT, oxLDL, RT-qPCR
29  2020 Lymphoid Neoplasms With Plasmablastic Differentiation: A Comprehensive Review and Diagnostic Approaches. HHV-8, IRF4, PRDM1
30  2020 MicroRNA-674-5p induced by HIF-1alpha targets XBP-1 in intestinal epithelial cell injury during endotoxemia. HIF-1alpha, IECs, miR
31  2020 Mycoplasma hyopneumoniae Inhibits Porcine Beta-Defensin 2 Production by Blocking the Unfolded Protein Response To Facilitate Epithelial Adhesion and Infection. PBD-2, UPR
32  2020 Palmitate induces cardiomyocyte death via inositol requiring enzyme-1 (IRE1)-mediated signaling independent of X-box binding protein 1 (XBP1). ATF6, ER, FA, IRE1, PERK, SFA, UPR
33  2020 Prognostic and Clinicopathological Significance of X-Box-Binding Protein 1 and N-Acetyltransferase 1 in Gallbladder Cancer. ACs, GBC, NAT1, TNM
34  2020 Protein Palmitoylation Regulates Cell Survival by Modulating XBP1 Activity in Glioblastoma Multiforme. ER, GBM
35  2020 Regulation of immune response by S-1-propenylcysteine through autophagy-mediated protein degradation. ERK, IgA, IL, IRAK4, MyD88, NF, Pax5, S1PC, TLR
36  2020 Repression of viral gene expression and replication by the unfolded protein response effector XBP1u. ATF6, IRE1, MCMV, UPR
37  2020 Ribosome Assembly Factor URB1 Contributes to Colorectal Cancer Proliferation via Transcriptional Activation of ATF4. ATF4, CCNA2, ChIP, CRC
38  2020 Schizandrin B Mitigates Rifampicin-Induced Liver Injury by Inhibiting Endoplasmic Reticulum Stress. ARMET, ATF, CHOP, ER, GRP78, IRE1, PERK, RFP
39  2020 Selenoprotein S regulates adipogenesis through IRE1alpha-XBP1 pathway. ER, HFD, IRE1alpha, KD, SelS
40  2020 Sodium tanshinone IIA sulfonate protects against Abeta1-42-induced cellular toxicity by modulating Abeta-degrading enzymes in HT22 cells. AD, Bip, GSH-Px, IDE, MDA, NEP, p-eIF2alpha, p-PERK, PDI, ROS, SOD, STS
41  2020 Spliced X-box binding protein 1 induces liver cancer cell death via activating the Mst1-JNK-mROS signalling pathway. JNK, mROS
42  2020 Systemic Delivery of Aptamer-Conjugated XBP1 siRNA Nanoparticles for Efficient Suppression of HER2+ Breast Cancer. HER2, NPs, TNBC
43  2020 Targeting the IRE1-XBP1 axis to overcome endocrine resistance in breast cancer: Opportunities and challenges. ER, UPR
44  2020 Thapsigargin promotes colorectal cancer cell migration through upregulation of lncRNA MALAT1. ATF4, CRC, ER, IRE1, lncRNA, MALAT1, PKR, TG
45  2020 The cellular prion protein is a stress protein secreted by renal tubular cells and a urinary marker of kidney injury. ER
46  2020 The emerging role of XBP1 in cancer. bZIP, ER, ERS, MHC, UPR
47  2020 The UPR sensor IRE1alpha and the adenovirus E3-19K glycoprotein sustain persistent and lytic infections. AdV, ATF6, ER, PERK, UPR
48  2020 TNFalpha selectively activates the IRE1alpha/XBP1 endoplasmic reticulum stress pathway in human airway smooth muscle cells. ATF6, ER, HASM, Mfn2, PERK
49  2020 Toll-like receptor 2 (TLR2) engages endoplasmic reticulum stress sensor IRE1alpha to regulate retinal innate responses in Staphylococcus aureus endophthalmitis. ER, IRE1alpha, TLR2
50  2020 Transcriptional regulation of PRKAR2B by miR-200b-3p/200c-3p and XBP1 in human prostate cancer. cAMP, CRPC, PCa, PKA
51  2020 X-box binding protein 1 (XBP1): A key protein for renal osmotic adaptation. Its role in lipogenic program regulation. DGAT1, ER, GP, IRE1alpha, MDCK, RNase, SREBP, TonEBP, UPR
52  2020 XBP1 negatively regulates CENPF expression via recruiting ATF6alpha to the promoter during ER stress. ATF6alpha, BFA, CENPF, ChIP, ER, TG, TM
53  2020 Zinc supplementation alleviates endoplasmic reticulum stress during porcine oocyte in vitro maturation by upregulating zinc transporters. ER
54  2019 A2a adenosine receptor agonist improves endoplasmic reticulum stress in MIN6 cell line through protein kinase A/ protein kinase B/ Cyclic adenosine monophosphate response element-binding protein/ and Growth Arrest And DNA-Damage-Inducible 34/ eukaryotic Initiation Factor 2alpha pathways. A2aR, Bcl-2, BiP, BrdU, cAMP, CHOP, ER, FITC, GADD34, p-Akt, p-eIF2alpha, PBC, PKA, TM
55  2019 Acute thiamethoxam toxicity in honeybees is not enhanced by common fungicide and herbicide and lacks stress-induced changes in mRNA splicing. elav
56  2019 An in vitro validation of the therapeutic effects of Tougu Xiaotong capsule on tunicamycin-treated chondrocytes. ER, miR-211, OA, TM, TXC
57  2019 Bardet-Biedl syndrome obesity: BBS4 regulates cellular ER stress in early adipogenesis. BBS, ER, UPR
58  2019 Carbon monoxide releasing molecule-3 alleviates neuron death after spinal cord injury via inflammasome regulation. CO, CORM-3, HO, IRE1, OGD, SCI
59  2019 Cigarette Smoke Extract Promotes Human Lung Myofibroblast Differentiation by the Induction of Endoplasmic Reticulum Stress. 4-PBA, alpha-SMA, ATF6, CSE, ER, GRP78, IPF, IRE1, TG
60  2019 Downregulation of XBP1 decreases serous ovarian cancer cell viability and enhances sensitivity to oxidative stress by increasing intracellular ROS levels. ER, MAPK, ROS, shRNA, SOC
61  2019 E-cigarette aerosols induce unfolded protein response in normal human oral keratinocytes. ATF4, BiP, CHOP, ECs, IPA, IRE1alpha, NHOKs, PERK, UPR
62  2019 Efavirenz and Efavirenz-like Compounds Activate Human, Murine, and Macaque Hepatic IRE1alpha-XBP1. EFV, IRE1alpha, PXR
63  2019 Effect of 50-Hz Magnetic Fields on Serum IL-1beta and IL-23 and Expression of BLIMP-1, XBP-1, and IRF-4. Blimp-1, ELISA, IRF4, MFs, RT-qPCR
64  2019 Effect of Kinase Inhibiting RNase Attenuator (KIRA) Compounds on the Formation of Face-to-Face Dimers of Inositol-Requiring Enzyme 1: Insights from Computational Modeling. IRE1alpha, KIRA, UPR
65  2019 Effects of Endoplasmic Reticulum Stress Inhibitor Treatment during the Micromanipulation of Somatic Cell Nuclear Transfer in Porcine Oocytes. Bax, ER, SCNT, TUDCA
66  2019 Endoplasmic reticulum quality control of LDLR variants associated with familial hypercholesterolemia. FH, LDLR, VLDLR
67  2019 Endoplasmic Reticulum Stress Induces MUC5AC and MUC5B Expression in Human Nasal Airway Epithelial Cells. ATF6, CHOP, ER, siRNA
68  2019 Endoplasmic reticulum-associated degradation potentiates the infectivity of influenza A virus by regulating the host redox state. 4-PBA, ER, ERAD, IAV, IRE1, MEFs, ROS
69  2019 Environmental Control of Astrocyte Pathogenic Activities in CNS Inflammation. EAE, IRE1alpha, MS
70  2019 Exon1 and -116 C/G Promoter Polymorphism on the X-Box DNA Binding Protein- 1 Gene is not Associated with Breast Cancer among Jordanian Women. BC, CIs, ORs, PCR, SNPs
71  2019 Expression of genes related to energy metabolism and the unfolded protein response in dairy cow mammary cells is affected differently during dietary supplementation with energy from protein and fat. BCAT1, ER, HF, HP, HP/HF, HP/LF, LP/HF, LP/LF, TCA
72  2019 Genipin attenuates mitochondrial-dependent apoptosis, endoplasmic reticulum stress, and inflammation via the PI3K/AKT pathway in acute lung injury. ALI, BCL2, ERS, GRP78, IL, LPS, NF-kappaB, PI3K, TNF-alpha
73  2019 Hippo Signaling Controls NLR Family Pyrin Domain Containing 3 Activation and Governs Immunoregulation of Mesenchymal Stem Cells in Mouse Liver Injury. IR, MSC, NLRP3, YAP
74  2019 Human placenta-derived mesenchymal stem cells inhibit apoptosis of granulosa cells induced by IRE1alpha pathway in autoimmune POF mice. ER, GCs, hPMSCs, IRE1alpha, POF, ZP3
75  2019 Impact of Bevacizumab on Liver Damage After Massive Hepatectomy in Rats. ATF6, CHOP, GRP78, HSP70, IL1B, MMP, TNFa
76  2019 Induction of autophagy-dependent apoptosis in cancer cells through activation of ER stress: an uncovered anti-cancer mechanism by anti-alcoholism drug disulfiram. DSF, IRE1alpha, UPR
77  2019 Inhibition of the Low Molecular Weight Protein Tyrosine Phosphatase (LMPTP) as a Potential Therapeutic Strategy for Hepatic Progenitor Cells Lipotoxicity-Short Communication. ATF6, CHOP, CMA, EMS, HPCs, HSC70, IR, IRE1alpha, LAMP2, LMPTP, PRKN
78  2019 Inositol-requiring enzyme 1 alpha endoribonuclease specific inhibitor STF-083010 protects the liver from thioacetamide-induced oxidative stress, inflammation and injury by triggering hepatocyte autophagy. CQ, ER, IRE1alpha, ROS, TAA
79  2019 L-lysine protects C2C12 myotubes and 3T3-L1 adipocytes against high glucose damages and stresses. ERS, HG, LC3, Lys, NO, p-eIF2alpha, ROS, UPR
80  2019 Loss of X-box binding protein 1 in Muller cells augments retinal inflammation in a mouse model of diabetes. ATF, eIF, ER, JNK, MG, VEGF
81  2019 Loss of XBP1 Leads to Early-Onset Retinal Neurodegeneration in a Mouse Model of Type I Diabetes. ER, UPR
82  2019 Mechanoregulation of p38 activity enhances endoplasmic reticulum stress-mediated inflammation by arterial endothelium. ER, ICAM-1, PECAM-1, SS
83  2019 Merits and pitfalls of conventional and covalent docking in identifying new hydroxyl aryl aldehyde like compounds as human IRE1 inhibitors. ER, HAA, UPR
84  2019 MicroRNA-326 suppresses iNOS expression and promotes autophagy of dopaminergic neurons through the JNK signaling by targeting XBP1 in a mouse model of Parkinson's disease. iNOS, miRNAs, PD
85  2019 Mild heat stress induces transcription of the beta-casein gene via unfolded protein response-activated XBP1 signaling in undifferentiated mammary epithelial cells. ATF6alpha, UPR
86  2019 miR-34c-5p modulates X-box-binding protein 1 (XBP1) expression during the adaptive phase of the unfolded protein response. ER, UPR
87  2019 Nuclear factor-kappa B-dependent X-box binding protein 1 signalling promotes the proliferation of nucleus pulposus cells under tumour necrosis factor alpha stimulation. IDD, IVD, NF-kappaB, NPCs, TNF-alpha, UPR
88  2019 Phosphorylation of AKT serine/threonine kinase and abundance of milk protein synthesis gene networks in mammary tissue in response to supply of methionine in periparturient Holstein cows. ATF6, CSN1S1, IARS, IRS-1, JAK2, mTORC1, PPP1R15A, rpS6, SLC2A1, SLC2A3
89  2019 Polyphenol-rich extract induces apoptosis with immunogenic markers in melanoma cells through the ER stress-associated kinase PERK. ER, ICD, PERK
90  2019 Quantitative Proteomic Analysis Reveals Unfolded-Protein Response Involved in Severe Fever with Thrombocytopenia Syndrome Virus Infection. ATF6, GP, IRE1, iTRAQ, PERK, SFTS, SFTSV, SFTSV, UPR
91  2019 Real-time PCR quantification of spliced X-box binding protein 1 (XBP1) using a universal primer method. ER, IRE1alpha, UPR
92  2019 Smac mimetic suppresses tunicamycin-induced apoptosis via resolution of ER stress. CHOP, cIAP, ER, GRP78, IAP, NF-kappaB, PERK, Smac, TG, TM, UPR
93  2019 Terminalia Arjuna bark extract impedes foam cell formation and promotes apoptosis in ox-LDL-stimulated macrophages by enhancing UPR-CHOP pathway. aqTAE, CHOP, DUSP1, ORO, PMA, TA, UPR
94  2019 The change tendency of endoplasmic reticulum stress associated proteins in rats with spinal cord injury. CHOP, ER, GRP78
95  2019 The Expression of Myeloproliferative Neoplasm-Associated Calreticulin Variants Depends on the Functionality of ER-Associated Degradation. ER, ERAD, JAK-STAT, MPN, UPR, WT
96  2019 The IRE1 endoplasmic reticulum stress sensor activates natural killer cell immunity in part by regulating c-Myc. NK
97  2019 The multiple roles of the unfolded protein response regulator IRE1alpha in cancer. ER, IRE1alpha, mRNA, UPR
98  2019 The oncogenic role of GNL3 in the progression and metastasis of osteosarcoma. EMT
99  2019 The role of X-box binding protein 1 in the hepatic response to refeeding in mice. UPR
100  2019 The Toll-Like Receptor/MyD88/XBP1 Signaling Axis Mediates Skeletal Muscle Wasting during Cancer Cachexia. ER, LLC, MyD88, TLRs, UPR