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Abbreviation : ZOL
Long Form : zoledronate
No. Year Title Co-occurring Abbreviation
2021 Characteristics of Human Peripheral Blood γδ T Cells Expanded With Zoledronate. ---
2021 Chemoattractants driven and microglia based biomimetic nanoparticle treating TMZ-resistant glioblastoma multiforme. FPPS, GAM, GBM, TMZ
2021 Comparative Effect of Zoledronate at 6 Versus 18 Months Following Denosumab Discontinuation. BMD, FN, LS
2021 Denosumab versus zoledronate for the treatment of low bone mineral density in male HIV-infected patients. ART, BMD, Dmab, FN, LS, PLWH
2021 Inhibition Effect of Zoledronate on the Osteoclast Differentiation of RAW264.7 Induced by Titanium Particles. Ti, TRAP
2021 Long-Term Efficacy of Intensive Zoledronate Therapy and Predictors of Retreatment in Paget's Disease of Bone. BAP, PDB
2021 Matrix-Bound Zolzoledronate Enhances the Biofilm Colonization of Hydroxyapatite: Effects on Osteonecrosis. Ai, Fn, MRONJ, Pg
2021 Nitrogen-containing bisphosphonates and lipopolysaccharide mutually augment inflammation via adenosine triphosphate (ATP)-mediated and interleukin 1beta (IL-1beta)-mediated production of neutrophil extracellular traps (NETs). ALE, ASBMR, ATP, BPs, IL-1beta, N-BPs, NETs, P2X7
2021 Small Extracellular Vesicles Derived from Adipose Tissue Prevent Bisphosphonate-Related Osteonecrosis of the Jaw by Promoting Angiogenesis. BRONJ, DEX, ECM, HUVECs, sEV-AT
10  2021 Topical co-administration of zoledronate with recombinant human bone morphogenetic protein-2 can induce and maintain bone formation in the bone marrow environment. beta-TCP, BMPs, CT, MT, rhBMP-2
11  2021 Treatment With Zoledronate Subsequent to Denosumab in Osteoporosis: A 2-Year Randomized Study. ASBMR, BMD, FN, LS, OBS, TH
12  2021 Zoledronate Bound to Ceramics Increases Ectopic Bone Volume Induced by rhBMP6 Delivered in Autologous Blood Coagulum in Rats. ABC, ABGS, BV
13  2020 A Drug Holiday Reduces the Frequency and Severity of Medication-Related Osteonecrosis of the Jaw in a Minipig Model. AR, MRONJ
14  2020 Bone-seeking nanoplatform co-delivering cisplatin and zoledronate for synergistic therapy of breast cancer bone metastasis and bone resorption. ALN, DSP
15  2020 Bone-Targeted Calcium Phosphate-Polymer Hybrid Nanoparticle Co-Deliver Zoledronate and Docetaxel to Treat Bone Metastasis of Prostate Cancer. DTX
16  2020 Clinical Research of the Application of Bone Turnover Markers in Monitoring the Short-Term Therapeutic Efficacy of Vitamin D in Postmenopausal Osteoporotic women in Harbin, China. BMD, BTM, OP, PMO, VitD
17  2020 Effects of bisphosphonates on osteoporosis: Focus on zoledronate. BPs
18  2020 Effects of follow-on therapy after denosumab discontinuation in patients with postmenopausal osteoporosis. BMD, BP, Dmab, FN, LS, RAL, TPTD, wmBP
19  2020 Histomorphometric Evaluation of Peri-Implant Bone Response to Intravenous Administration of Zoledronate (Zometa) in an Osteoporotic Rat Model. ---
20  2020 Potent Bidirectional Cross-Talk Between Plasmacytoid Dendritic Cells and gammadeltaT Cells Through BTN3A, Type I/II IFNs and Immune Checkpoints. pAgs, pDCs
21  2020 Role of dendritic cell-mediated immune response in oral homeostasis: A new mechanism of osteonecrosis of the jaw. DC
22  2020 The BTLA and PD-1 signaling pathways independently regulate the proliferation and cytotoxicity of human peripheral blood gammadelta T cells. BTLA, HVEM, PD-1
23  2020 Treatment with Zoledronate Subsequent to Denosumab in Osteoporosis: a Randomized Trial. LS-BMD
24  2020 Zoledronate decreases CTLA-4 in vivo and in vitro independently of its action on bone resorption. APR, CTLA-4, IRDs, N-BPs, PBMCs
25  2020 Zoledronate inhibits the differentiation potential of adipose-derived stem cells into osteoblasts in repairing jaw necrosis. ADSCs, CTSK, FGFR3
26  2020 [Zoledronate regulates osteoclast differentiation and bone resorption in high glucose through p38 MAPK pathway]. ---
27  2019 Anti-Tumor Effects of Low Dose Zoledronate on Lung Cancer-Induced Spine Metastasis. ---
28  2019 Efficiency of Zoledronic Acid in Inhibiting Accelerated Periprosthetic Bone Loss After Cementless Total Hip Arthroplasty in Osteoporotic Patients: A Prospective, Cohort Study. BMD, EQ-5D, THA
29  2019 Histological evaluation of the healing process of autografted mandibular bone defects in rats under treatment with zoledronate. ---
30  2019 Low-dose zoledronate for the treatment of bone metastasis secondary to prostate cancer. BPs
31  2019 Microcirculatory consequences of limb ischemia/reperfusion in ovariectomized rats treated with zoledronic acid. BIS, IR
32  2019 Nitrogen Containing Bisphosphonates Impair the Release of Bone Homeostasis Mediators and Matrix Production by Human Primary Pre-Osteoblasts. ALN, BPs
33  2019 PDGF-BB exhibited therapeutic effects on rat model of bisphosphonate-related osteonecrosis of the jaw by enhancing angiogenesis and osteogenesis. BMMSCs, BRONJ, ELISA, PDGF-BB
34  2019 Rescue bisphosphonate treatment of alveolar bone improves extraction socket healing and reduces osteonecrosis in zoledronate-treated mice. BP, MRONJ, N-BP
35  2019 Skeletal levels of bisphosphonate in the setting of chronic kidney disease are independent of remodeling rate and lower with fractionated dosing. BP, CKD, NL
36  2019 Suppressive effects of N-bisphosphonate in osteoblastic cells mitigated by non-N-bisphosphonate but not by sodium-dependent phosphate cotransporter inhibitor. BPs, ETI
37  2019 Synthetic Calcium Phosphate Ceramics as a Potential Treatment for Bisphosphonate-Related Osteonecrosis of the Jaw. BCP, BPs, BRONJ, CP, HGF
38  2019 Vitamin C promotes the proliferation and effector functions of human gammadelta T cells. pAgs, VC
39  2019 Zoledronate and Raloxifene combination therapy enhances material and mechanical properties of diseased mouse bone. OI, RAL, WT
40  2019 Zoledronate for the Prevention of Bone Loss in Women Discontinuing Denosumab Treatment. A Prospective 2-Year Clinical Trial. Dmab, FN, LS-BMD, P1NP
41  2019 Zoledronate induces cell cycle arrest and differentiation by upregulating p21 in mouse MC3T3-E1 preosteoblasts. OCN, qPCR, siRNAs
42  2019 Zoledronate treatment duration is linked to bisphosphonate-related osteonecrosis of the jaw prevalence in rice rats with generalized periodontitis. BRONJ, PD
43  2019 Zoledronic Acid-containing Nanoparticles With Minimum Premature Release Show Enhanced Activity Against Extraskeletal Tumor. ---
44  2018 Acute-phase reaction induced by zoledronate and its effect on prognosis of patients with advanced non-small cell lung cancer. APR, APR, NSCLC, OS
45  2018 Cytotoxic and inflammatory effects of alendronate and zolendronate on human osteoblasts, gingival fibroblasts and osteosarcoma cells. FDA
46  2018 Density functional theory studies on a non-covalent interaction system: hydrogen-bonded dimers of zoledronate. DFT
47  2018 Possible Application of Ascites-infiltrating Gamma-delta T Cells for Adoptive Immunotherapy. 2M3B1PP, AILs, PBMCs
48  2018 The effects of bisphosphonates on osteonecrosis of jaw bone: a stem cell perspective. ALE, BIONJ, BPs, DPSCs, DSC, hTGSCs, PDLSCs, RIS
49  2018 Valproic Acid Combined with Zoledronate Enhance gammadelta T Cell-Mediated Cytotoxicity against Osteosarcoma Cells via the Accumulation of Mevalonate Pathway Intermediates. VPA
50  2018 Zoledronate and high glucose levels influence osteoclast differentiation and bone absorption via the AMPK pathway. CTSK, NFATc1, Syk, TRAP
51  2017 Bisphosphonates hinder osteoblastic/osteoclastic differentiation in the maxillary sinus mucosa-derived stem cells. ALN, ALP, BMMs, BPs, HMSMCs, RANKL
52  2017 Development of fever following first administration of zoledronate as a prognostic factor in advanced non-small cell lung cancer patients with bone metastases. N-BPs
53  2017 Effect of local zoledronate delivery on osseointegration: a systematic review of preclinical studies. ---
54  2017 Expression of Dlx-5 and Msx-1 in Craniofacial Skeletons and Ilia of Rats Treated With Zoledronate. DLX
55  2017 Factors associated with acute-phase response of bisphosphonate-naive or pretreated women with osteoporosis receiving an intravenous first dose of zoledronate or ibandronate. APR, BP, IBN
56  2017 Improving Combination Osteoporosis Therapy in a Preclinical Model of Heightened Osteoanabolism. ALN, PTH, RAL
57  2017 Nano-technology based carriers for nitrogen-containing bisphosphonates delivery as sensitisers of gammadelta T cells for anticancer immunotherapy. ALD, N-BPs
58  2017 Raloxifene Improves Bone Mechanical Properties in Mice Previously Treated with Zoledronate. RAL, VEH
59  2017 Skeletal Site-specific Effects of Zoledronate on in vivo Bone Remodeling and in vitro BMSCs Osteogenic Activity. ALP, BPs, BRON, BRONJ
60  2017 The effects of ozone application on genotoxic damage and wound healing in bisphosphonate-applied human gingival fibroblast cells. ALN, MRONJ, PAM
61  2017 The Pharmacological Profile of a Novel Highly Potent Bisphosphonate, OX14 (1-Fluoro-2-(Imidazo-[1,2-alpha]Pyridin-3-yl)-Ethyl-Bisphosphonate). FPPS, HAP, MIN, RIS
62  2017 Zoledronate can induce colorectal cancer microenvironment expressing BTN3A1 to stimulate effector gammadelta T cells with antitumor activity. CRC, N-BPs, PAg, TAF
63  2016 Aminobisphosphonates Synergize with Human Cytomegalovirus To Activate the Antiviral Activity of Vgamma9Vdelta2 Cells. HCMV
64  2016 Evaluation of BP-ONJ in osteopenic and healthy sheep: comparing ZTE-MRI with CT. BP-ONJ, CT, ZTE-MRI
65  2016 Folate-targeted pH-responsive calcium zoledronate nanoscale metal-organic frameworks: Turning a bone antiresorptive agent into an anticancer therapeutic. CaZol, FOL, FR, i.v, NMOFs, PEG
66  2016 Hepatocellular carcinoma cell sensitivity to Vgamma9Vdelta2 T lymphocyte-mediated killing is increased by zoledronate. CTLs, HCC
67  2016 Local Administration of Bisphosphonate-soaked Hydroxyapatite for the Treatment of Osteonecrosis of the Femoral Head in Rabbit. HA, ONFH
68  2016 Local co-application of zoledronate promotes long-term maintenance of newly formed bone induced by recombinant human bone morphogenetic protein 2. beta-TCP, BMPs, rhBMP-2
69  2016 Peripheral blood-derived, gamma9delta2 t cell-enriched cell lines from glioblastoma multiforme patients exert anti-tumoral effects in vitro. ABP, GBM, GBMDCL, HD, IFN, IL, PB, TMZ
70  2016 Plasticity of Myeloid Cells during Oral Barrier Wound Healing and the Development of Bisphosphonate-related Osteonecrosis of the Jaw. ONJ
71  2016 Zoledronate and Molecular Iodine Cause Synergistic Cell Death in Triple Negative Breast Cancer through Endoplasmic Reticulum Stress. ER
72  2015 A mouse model of luciferase-transfected stromal cells of giant cell tumor of bone. BLI, GCT, IHC
73  2015 Bisphosphonate Induces Osteonecrosis of the Jaw in Diabetic Mice via NLRP3/Caspase-1-Dependent IL-1beta Mechanism. BRONJ, NLR, ROS
74  2015 Bisphosphonate-induced differential modulation of immune cell function in gingiva and bone marrow in vivo: role in osteoclast-mediated NK cell activation. ALN, BPs, ETI, NK, ONJ
75  2015 Drug delivery and cell interaction of adhesive poly(ethyleneimine)/sulfated polysaccharide complex particle films. CS, DLS, DS, Ge, NPs, PEC, PEI
76  2015 Effect of antiresorptive and anabolic bone therapy on development of osteoarthritis in a posttraumatic rat model of OA. DWB, MM, OA, PTH
77  2015 Liposome encapsulated zoledronate favours M1-like behaviour in murine macrophages cultured with soluble factors from breast cancer cells. 4T1CM, BPs, CLO, MMPs, TAMs
78  2015 Low-intensity continuous ultrasound triggers effective bisphosphonate anticancer activity in breast cancer. US
79  2015 Nephrotoxicity of ibandronate and zoledronate in Wistar rats with normal renal function and after unilateral nephrectomy. IBN
80  2015 Polyoxomolybdate Bisphosphonate Heterometallic Complexes: Synthesis, Structure, and Activity on a Breast Cancer Cell Line. ALE
81  2015 Strontium and zoledronate hydroxyapatites graded composite coatings for bone prostheses. C-MAPLE, SrHA, ZOLHA
82  2015 The combined use of Camellia sinensis and metronomic zoledronate in 4T1 mouse carcinoma against tumor growth and metastasis. CS, MMP
83  2015 The Effect of Interferon-gamma and Zoledronate Treatment on Alpha-Tricalcium Phosphate/Collagen Sponge-Mediated Bone-Tissue Engineering. IFN
84  2015 The effects of zoledronate on the survival and function of human osteoblast-like cells. ---
85  2015 The inhibition of human farnesyl pyrophosphate synthase by nitrogen-containing bisphosphonates. Elucidating the role of active site threonine 201 and tyrosine 204 residues using enzyme mutants. FPPS, IPP, N-BPs, RIS, Thr201, Tyr204
86  2015 Trastuzumab enhanced the cytotoxicity of Vgamma9Vdelta2 T cells against zoledronate-sensitized osteosarcoma cells. ABP, ADCC, OS, TTZ
87  2015 Vgamma9Vdelta2 T cells and zoledronate mediate antitumor activity in an orthotopic mouse model of human chondrosarcoma. CS
88  2015 Zoledronate Attenuates Accumulation of DNA Damage in Mesenchymal Stem Cells and Protects Their Function. MSCs
89  2015 Zoledronate can promote apoptosis and inhibit the proliferation of colorectal cancer cells. BP
90  2015 Zoledronate induces osteonecrosis of the jaw in sheep. MRONJ
91  2015 [Effect of zoledronate on the osteoclast adhesion and gene expression of integrin alpha(v) and beta3]. TRAP
92  2014 A Novel Prothrombotic Pathway in Systemic Sclerosis Patients: Possible Role of Bisphosphonate-Activated gammadelta T Cells. ABP, HD, IL, LPS, PB, SSc, TF, TNF
93  2014 Bone formation on biomimetic calcium phosphate-coated and zoledronate-immobilized titanium implants in osteoporotic rat tibiae. CaP
94  2014 Cast adhesive polyelectrolyte complex particle films of unmodified or maltose-modified poly(ethyleneimine) and cellulose sulphate: fabrication, film stability and retarded release of zoledronate. Ge, IB, PEC, PEI, PEI-M
95  2014 Controlled delivery of zoledronate improved bone formation locally in vivo. BPs, PLGA
96  2014 Cortical bone loss at the tibia in postmenopausal women with osteoporosis is associated with incident non-vertebral fractures: results of a randomized controlled ancillary study of HORIZON. BMD, FN, LS, PLB, T-EPI, TH
97  2014 CSF-1 blockade impairs breast cancer osteoclastogenic potential in co-culture systems. DEN
98  2014 Distinct effect of zoledronate and clodronate on circulating levels of DKK1 and sclerostin in women with postmenopausal osteoporosis. DKK1, SOST
99  2014 Effects of zoledronic acid versus placebo on bone mineral density and bone texture analysis assessed by the trabecular bone score in premenopausal women with breast cancer treatment-induced bone loss: results of the ProBONE II substudy. BC, BMD, LS, PLB, TBS
100  2014 Impaired bone resorption and woven bone formation are associated with development of osteonecrosis of the jaw-like lesions by bisphosphonate and anti-receptor activator of NF-kappaB ligand antibody in mice. Ab, ONJ, RANKL, TRAP