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Abbreviation : cRGD
Long Form : cyclic arginine-glycine-aspartic acid
No. Year Title Co-occurring Abbreviation
2020 A novel alphavbeta3 integrin-targeted NIR-II nanoprobe for multimodal imaging-guided photothermal therapy of tumors in vivo. PA, PTT, SPECT
2020 Functional supramolecular bioactivated electrospun mesh improves tissue ingrowth in experimental abdominal wall reconstruction in rats. PC, POP, UPy
2019 An activated-platelet-sensitive nanocarrier enables targeted delivery of tissue plasminogen activator for effective thrombolytic therapy. tPA
2019 Application of Triarylboron Substituted with Cyclic Arginine-Glycine-Aspartic Acid Motifs as a Multivalent Two-Photon Fluorescent Probe for Tumor Imaging in Vivo. TAB
2019 Near-infrared light-regulated cancer theranostic nanoplatform based on aggregation-induced emission luminogen encapsulated upconversion nanoparticles. AIEgen, PDT, PSs, ROS, UCNPs
2019 PAMAM-cRGD mediating efficient siRNA delivery to spermatogonial stem cells. CCK-8, FTIR, PAMAM, siRNAs, SSCs, TEM
2018 Cyclic RGD-conjugated Pluronic blending system for active, targeted drug delivery. ---
2018 Gelofusine Attenuates Tubulointerstitial Injury Induced by cRGD-Conjugated siRNA by Regulating the TLR3 Signaling Pathway. NF-kappaB, siRNA, TLR3
2018 Protective effect of Gelofusine against cRGD-siRNA-induced nephrotoxicity in mice. BUN, siRNA, TUNEL
10  2018 Theranostics of Triple-Negative Breast Cancer Based on Conjugated Polymer Nanoparticles. ACQ, CP, MEH-PPV, PDT, ROS, TNBC
11  2018 Ultrasmall hybrid protein-copper sulfide nanoparticles for targeted photoacoustic imaging of orthotopic hepatocellular carcinoma with a high signal-to-noise ratio. BSA, HCC
12  2017 A tumor-targeting cRGD-EGFR siRNA conjugate and its anti-tumor effect on glioblastoma in vitro and in vivo. cRGD-siEGFR, EGFR
13  2017 Cyclic RGD peptide-modified liposomal drug delivery system for targeted oral apatinib administration: enhanced cellular uptake and improved therapeutic effects. PEG
14  2017 Design and Evaluation of RGD-Modified Gemini Surfactant-Based Lipoplexes for Targeted Gene Therapy in Melanoma Model. RAD, RGD-G
15  2017 Extremely small-sized globular poly(ethylene glycol)-cyclic RGD conjugates targeting integrin alphavbeta3 in tumor cells. Ce6, gPEG
16  2017 NIR Emitting Nanoprobes Based on Cyclic RGD Motif Conjugated PbS Quantum Dots for Integrin-Targeted Optical Bioimaging. NIR, QDs
17  2017 Structure-Dependent Antimicrobial Theranostic Functions of Self-Assembled Short Peptide Nanoagents. AMP, MRI
18  2017 Ultrasmall Conjugated Polymer Nanoparticles with High Specificity for Targeted Cancer Cell Imaging. CPN30, CPN6, CPN6, CPNs, eta
19  2017 Ultrasound molecular imaging with cRGD-PLGA-PFOB nanoparticles for liver fibrosis staging in a rat model. NPs, PFOB, US
20  2016 Aggregation Induced Emission Fluorogens Based Nanotheranostics for Targeted and Imaging-Guided Chemo-Photothermal Combination Therapy. AIE, PPy, PTX
21  2016 Dual-targeted activatable photosensitizers with aggregation-induced emission (AIE) characteristics for image-guided photodynamic cancer cell ablation. AIE, PDT, PSs, ROS
22  2016 Fabrication of RGD-conjugated Gd(OH)3:Eu nanorods with enhancement of magnetic resonance, luminescence imaging and in vivo tumor targeting. Mal-PEG-NHS, MRI, NCS, ROS
23  2015 Conjugated polymer and drug co-encapsulated nanoparticles for chemo- and photo-thermal combination therapy with two-photon regulated fast drug release. CI, CP, DNQ, DOX, NIR, NPs
24  2015 Endothelial cell-targeted pVEGF165 polyplex plays a pivotal role in inhibiting intimal thickening after vascular injury. HUVECs, VEGF
25  2015 RGD-conjugated solid lipid nanoparticles inhibit adhesion and invasion of alphavbeta3 integrin-overexpressing breast cancer cells. MPS, PEG, RGD-SLNs
26  2015 ss3-integrin inhibits lipopolysaccharide-induced autophagy in cardiomyocytes via the Akt signaling pathway. LPS, MDC
27  2014 Construction and evaluation of Fe₃O₄-based PLGA nanoparticles carrying rtPA used in the detection of thrombosis and in targeted thrombolysis. CS, PLGA, rt-PA, SNR, TEM
28  2014 Self-assembled nanoparticles based on PEGylated conjugated polyelectrolyte and drug molecules for image-guided drug delivery and photodynamic therapy. CPE, NPs, PEG
29  2014 Targeted theranostic platinum(IV) prodrug with a built-in aggregation-induced emission light-up apoptosis sensor for noninvasive early evaluation of its therapeutic responses in situ. AIE, TPS
30  2014 Temperature-triggered tumor-specific delivery of anticancer agents by cRGD-conjugated thermosensitive liposomes. DOX, DPPC, ELP
31  2013 Cyclic arginine-glycine-aspartate attenuates acute lung injury in mice after intestinal ischemia/reperfusion. ALI, I/R
32  2013 Retargeting vesicular stomatitis virus glycoprotein pseudotyped lentiviral vectors with enhanced stability by in situ synthesized polymer shell. VSV-G
33  2012 Bio-orthogonal polymer coatings for co-presentation of biomolecules. CVD, EGF, HUVEC, Pfp-ester
34  2012 Bufalin-loaded mPEG-PLGA-PLL-cRGD nanoparticles: preparation, cellular uptake, tissue distribution, and anticancer activity. BNPs, mPEG, NPs, PLGA, PLL
35  2012 cRGD conjugated mPEG-PLGA-PLL nanoparticles for SGC-7901 gastric cancer cells-targeted Delivery of fluorouracil. 5Fu, CLSM
36  2012 Insonation of targeted microbubbles produces regions of reduced blood flow within tumor vasculature. FITC, NDL
37  2012 Ligand-decorated nanogels: fast one-pot synthesis and cellular targeting. T-NGs
38  2012 Specific detection of integrin alphavbeta3 by light-up bioprobe with aggregation-induced emission characteristics. AIE
39  2011 Molecular imaging of hepatic stellate cell activity by visualization of hepatic integrin alphavbeta3 expression with SPECT in rat. HSCs, mRNA, SPECT
40  2011 Near-infrared pH-activatable fluorescent probes for imaging primary and metastatic breast tumors. NIR
41  2011 Ultrasound molecular imaging of tumor angiogenesis with an integrin targeted microbubble contrast agent. MB, MI, PDP
42  2010 Albumin nanoshell encapsulation of near-infrared-excitable rare-Earth nanoparticles enhances biocompatibility and enables targeted cell imaging. ---
43  2010 Functionalized near-infrared quantum dots for in vivo tumor vasculature imaging. NIR, PEG, QDs
44  2010 Integrin-targeting thermally cross-linked superparamagnetic iron oxide nanoparticles for combined cancer imaging and drug delivery. cRGD_TCL-SPION, DOX, MR, TCL-SPION
45  2006 Cyclic arginine-glycine-aspartic acid peptide inhibits macrophage infiltration of the kidney and carotid artery lesions in apo-E-deficient mice. APOE
46  2004 Atomic force microscopy measurement of leukocyte-endothelial interaction. AFM, HUVECs