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[Related PubMed/MEDLINE]
Total Number of Papers: 244
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| Abbreviation |
: eIF2 |
| Long Form |
: eukaryotic initiation factor 2 |
|
| No. |
Year |
Title |
Co-occurring Abbreviation |
| 1 |
2020 |
Clinical and Proteomic Correlates of Plasma ACE2 (Angiotensin-Converting Enzyme 2) in Human Heart Failure. |
ACE2, COVID-19, PHFS |
| 2 |
2020 |
EIF2alpha phosphorylation is regulated in intracellular amastigotes for the generation of infective Trypanosoma cruzi trypomastigote forms. |
--- |
| 3 |
2020 |
Inbuilt tendency of the eIF2 regulatory system to counteract uncertainties. |
--- |
| 4 |
2020 |
Inhibition of protein kinase R by C16 protects the retinal ganglion cells from hypoxia-induced oxidative stress, inflammation, and apoptosis. |
IL-6, LDH, NAC, NF-kappaB, PKR, RGCs, ROS, ssDNA, TNF-alpha |
| 5 |
2020 |
Inhibition of the integrated stress response by viral proteins that block p-eIF2-eIF2B association. |
ISR, p-eIF2 |
| 6 |
2020 |
Interleukin-27 Gene Delivery Targeting IL-6Ralpha-Expressing Cells as a Stress Response Therapy. |
BH, eIF2alpha, IFN, IL-27, IPA, IRF, JAK/STAT, p-eIF2alpha |
| 7 |
2020 |
M. tuberculosis infection of human iPSDM reveals complex membrane dynamics during xenophagy evasion. |
iPSDM, LC3-TVS, Mtb |
| 8 |
2020 |
System-Wide Analysis of Protein Acetylation and Ubiquitination Reveals a Diversified Regulation in Human Cancer Cells. |
--- |
| 9 |
2020 |
Translation Regulation by eIF2alpha Phosphorylation and mTORC1 Signaling Pathways in Non-Communicable Diseases (NCDs). |
COPD, ISR, mTORC1, NCDs |
| 10 |
2019 |
Cellular eIF2B subunit localization: implications for the integrated stress response and its control by small molecule drugs. |
eIF2B, ISR |
| 11 |
2019 |
Dietary Sulfur Amino Acid Restriction and the Integrated Stress Response: Mechanistic Insights. |
ATF4, ISR, SAAR |
| 12 |
2019 |
Ileal Gene Expression Data from Crohn's Disease Small Bowel Resections Indicate Distinct Clinical Subgroups. |
cAMP, CD, NKT |
| 13 |
2019 |
Involvement of the eIF2alpha Kinase GCN2 in UV-B Responses. |
CHS, FADox, GCN2, GPX7, MKP1, RAD51 |
| 14 |
2019 |
Multiple mechanisms of Rottlerin toxicity in A375 melanoma cells. |
Bcl-2, ER |
| 15 |
2018 |
Arabidopsis ILITHYIA protein is necessary for proper chloroplast biogenesis and root development independent of eIF2alpha phosphorylation. |
ILA |
| 16 |
2018 |
Cannabinoid Modulation of Eukaryotic Initiation Factors (eIF2alpha and eIF2B1) and Behavioral Cross-Sensitization to Cocaine in Adolescent Rats. |
CBP, PP1, WIN |
| 17 |
2018 |
DENR-MCTS1 heterodimerization and tRNA recruitment are required for translation reinitiation. |
DENR, MCTS1, ORF |
| 18 |
2018 |
eIF1 Loop 2 interactions with Met-tRNAi control the accuracy of start codon selection by the scanning preinitiation complex. |
Met-tRNAi, PIC, TC |
| 19 |
2018 |
Eukaryotic Initiation Factor 5B (eIF5B) Cooperates with eIF1A and eIF5 to Facilitate uORF2-Mediated Repression of ATF4 Translation. |
ATF4, eIF5B, uORF |
| 20 |
2018 |
Identification of differentially expressed genes and pathways in mice exposed to mixed field neutron/photon radiation. |
--- |
| 21 |
2018 |
Modeling and Dynamic Behavior of eIF2 Dependent Regulatory System With Disturbances. |
--- |
| 22 |
2018 |
PEP-1-glutaredoxin-1 induces dedifferentiation of rabbit articular chondrocytes by the endoplasmic reticulum stress-dependent ERK-1/2 pathway and the endoplasmic reticulum stress-independent p38 kinase and PI-3 kinase pathways. |
ER, ERK, GRP, GRX-1 |
| 23 |
2018 |
Transcriptome-wide analysis uncovers the targets of the RNA-binding protein MSI2 and effects of MSI2's RNA-binding activity on IL-6 signaling. |
AML, CML, EGF, HGF, IL-6, MEME, MSI2, PAR-CLIP, pB-ALL, RRE, STAT3 |
| 24 |
2017 |
Crystal Structure of the C-terminal Domain of Human eIF2D and Its Implications on Eukaryotic Translation Initiation. |
--- |
| 25 |
2017 |
Human Keratinocyte Differentiation Requires Translational Control by the eIF2alphaKinase GCN2. |
GCN2 |
| 26 |
2017 |
Inhibition of PERK-dependent pro-adaptive signaling pathway as a promising approach for cancer treatment. |
ER, PKR, UPR |
| 27 |
2017 |
Obesity challenges the hepatoprotective function of the integrated stress response to asparaginase exposure in mice. |
apoB100, ATF4, ISR, mTORC1, PERK |
| 28 |
2017 |
Proteomic analysis reveals changes in carbohydrate and protein metabolism associated with broiler breast myopathy. |
IPA, mTOR, WB, WS |
| 29 |
2017 |
Role of Saccharomyces cerevisiae TAN1 (tRNA acetyltransferase) in eukaryotic initiation factor 2B (eIF2B)-mediated translation control and stress response. |
eIF2B, Sup-II |
| 30 |
2017 |
Salubrinal protects human skin fibroblasts against UVB-induced cell death by blocking endoplasmic reticulum (ER) stress and regulating calcium homeostasis. |
ER |
| 31 |
2017 |
Smad7 positively regulates keratinocyte proliferation in psoriasis. |
AS, TGF |
| 32 |
2017 |
The effects of administration of the Lactobacillus gasseri strain CP2305 on quality of life, clinical symptoms and changes in gene expression in patients with irritable bowel syndrome. |
IBS |
| 33 |
2017 |
Translational Control in the Latency of Apicomplexan Parasites. |
--- |
| 34 |
2016 |
An RNA trapping mechanism in Alphavirus mRNA promotes ribosome stalling and translation initiation. |
CDS |
| 35 |
2016 |
eIF2alpha phosphorylation controls thermal nociception. |
--- |
| 36 |
2016 |
General control nonderepressible 2 deletion predisposes to asparaginase-associated pancreatitis in mice. |
ER, FGF21, GCN2, Hspa5, Pap, PERK, sXbp1 |
| 37 |
2016 |
Human Cytomegalovirus pTRS1 and pIRS1 Antagonize Protein Kinase R To Facilitate Virus Replication. |
HCMV, PKR |
| 38 |
2016 |
OLA1, a Translational Regulator of p21, Maintains Optimal Cell Proliferation Necessary for Developmental Progression. |
MEFs |
| 39 |
2016 |
Role of GCN2-Independent Signaling Through a Noncanonical PERK/NRF2 Pathway in the Physiological Responses to Dietary Methionine Restriction. |
EAAs, ER, GCN2, ISR, MR |
| 40 |
2016 |
Temporal proteomic profiling of Chlamydia trachomatis-infected HeLa-229 human cervical epithelial cells. |
iTRAQ, mTOR |
| 41 |
2015 |
ABC50 mutants modify translation start codon selection. |
ABC50 |
| 42 |
2015 |
Bufalin Reverses Resistance to Sorafenib by Inhibiting Akt Activation in Hepatocellular Carcinoma: The Role of Endoplasmic Reticulum Stress. |
CHOP, ER, HCC, IRE1 |
| 43 |
2015 |
Cdc123, a Cell Cycle Regulator Needed for eIF2 Assembly, Is an ATP-Grasp Protein with Unique Features. |
--- |
| 44 |
2015 |
Fexofenadine regulates nuclear factor-kappaB signaling and endoplasmic reticulum stress in intestinal epithelial cells and ameliorates acute and chronic colitis in mice. |
DSS, ER, IL, PCR, TNF |
| 45 |
2015 |
GCN2 is required to increase fibroblast growth factor 21 and maintain hepatic triglyceride homeostasis during asparaginase treatment. |
AAR, FGF21, GCN2 |
| 46 |
2015 |
OLA1 regulates protein synthesis and integrated stress response by inhibiting eIF2 ternary complex formation. |
ISR, TC, tRNAi |
| 47 |
2015 |
p300 Regulates Liver Functions by Controlling p53 and C/EBP Family Proteins through Multiple Signaling Pathways. |
dnp300 |
| 48 |
2015 |
Somatostatin, neuronal vulnerability and behavioral emotionality. |
SST |
| 49 |
2015 |
Systems biology surveillance decrypts pathological transcriptome remodeling. |
ER, WT |
| 50 |
2015 |
Translation of 5' leaders is pervasive in genes resistant to eIF2 repression. |
ORFs, uORF |
| 51 |
2014 |
A functional role for Smad7 in sustaining colon cancer cell growth and survival. |
CDK, CRC, TGF |
| 52 |
2014 |
Human eukaryotic initiation factor 2 (eIF2)-GTP-Met-tRNAi ternary complex and eIF3 stabilize the 43 S preinitiation complex. |
PIC, TC |
| 53 |
2014 |
Involvement of the immune system, endocytosis and EIF2 signaling in both genetically determined and sporadic forms of Parkinson's disease. |
LRRK2, PBMC, PD |
| 54 |
2013 |
ApoE epsilon4 is associated with eIF2alpha phosphorylation and impaired learning in young mice. |
APOE, SAD |
| 55 |
2013 |
Endoplasmic reticulum stress contributes to Helicobacter pylori VacA-induced apoptosis. |
CHOP, ER, PERK, VacA |
| 56 |
2013 |
Maternal overweight induced by a diet with high content of saturated fat activates placental mTOR and eIF2alpha signaling and increases fetal growth in rats. |
eIF2alpha, HF, LPL, mTOR, mTORC1 |
| 57 |
2013 |
The eIF2alpha kinases: their structures and functions. |
ATF4, GCN2, HRI, ISR, PERK, PKR |
| 58 |
2013 |
The eukaryotic initiation factor 2 kinase GCN2 protects against hepatotoxicity during asparaginase treatment. |
AAR, GCN2 |
| 59 |
2013 |
The unfolded protein response in the protozoan parasite Toxoplasma gondii features translational and transcriptional control. |
ER, UPR |
| 60 |
2013 |
Translation initiation requires cell division cycle 123 (Cdc123) to facilitate biogenesis of the eukaryotic initiation factor 2 (eIF2). |
Cdc123 |
| 61 |
2013 |
Unfolded protein response pathways regulate Hepatitis C virus replication via modulation of autophagy. |
3-MA, ER, HCV, UPR, XBP1 |
| 62 |
2012 |
AIMP3/p18 controls translational initiation by mediating the delivery of charged initiator tRNA to initiation complex. |
AIMPs, Met, Met, MRS, MSC |
| 63 |
2012 |
Conformational transitions of the catalytic domain of heme-regulated eukaryotic initiation factor 2alpha kinase, a key translational regulatory molecule. |
CD, GdnHCl, HRI, KD, KI |
| 64 |
2012 |
Dephosphorylation of eIF2alpha is essential for protein synthesis increase and cell cycle progression after sea urchin fertilization. |
--- |
| 65 |
2012 |
Eukaryotic initiation factor 2 (eIF2) signaling regulates proinflammatory cytokine expression and bacterial invasion. |
--- |
| 66 |
2012 |
New insights into translational regulation in the endoplasmic reticulum unfolded protein response. |
ER, IRE1, UPR, XBP1 |
| 67 |
2012 |
Potential contribution of translational factors to triiodo-L-thyronine-induced insulin synthesis by pancreatic beta cells. |
4E-BP, eEF1A, THs |
| 68 |
2011 |
An inhibitor of eIF2 activity in the sRNA pool of eukaryotic cells. |
met-tRNAi, TCI |
| 69 |
2011 |
Development of transgenic mice expressing a conditionally active form of the eIF2alpha kinase PKR. |
GyrB, KD |
| 70 |
2011 |
Phosphorylation of eIF2 facilitates ribosomal bypass of an inhibitory upstream ORF to enhance CHOP translation. |
ISR, uORF |
| 71 |
2010 |
The eIF2 kinase GCN2 is essential for the murine immune system to adapt to amino acid deprivation by asparaginase. |
ASNase, GCN2 |
| 72 |
2010 |
The ribosome-bound initiation factor 2 recruits initiator tRNA to the 30S initiation complex. |
fMet, IF2 |
| 73 |
2009 |
ABC50 promotes translation initiation in mammalian cells. |
ABC |
| 74 |
2009 |
Crystal structure of the alpha subunit of human translation initiation factor 2B. |
eIF2B |
| 75 |
2009 |
Discovery of chemical modulators of a conserved translational control pathway by parallel screening in yeast. |
GCN, HTS |
| 76 |
2009 |
Genome-wide analysis of tRNA charging and activation of the eIF2 kinase Gcn2p. |
--- |
| 77 |
2009 |
The role of translational regulation in ultraviolet C light-induced cyclooxygenase-2 expression. |
COX-2, S51A, UV-C |
| 78 |
2009 |
Understanding mechanisms and the role of differentiation in pathogenesis of Toxoplasma gondii: a review. |
--- |
| 79 |
2008 |
Acute and chronic ethanol consumption differentially impact pathways limiting hepatic protein synthesis. |
--- |
| 80 |
2008 |
Alanyl-glutamine consumption modifies the suppressive effect of L-asparaginase on lymphocyte populations in mice. |
--- |
| 81 |
2008 |
Attenuation of depression of muscle protein synthesis induced by lipopolysaccharide, tumor necrosis factor, and angiotensin II by beta-hydroxy-beta-methylbutyrate. |
Ang II, HMB, IFN-gamma, LPS, mTOR, PKR, TNF-alpha |
| 82 |
2008 |
Intersubunit and interprotein interactions of alpha- and beta-subunits of human eIF2: Effect of phosphorylation. |
--- |
| 83 |
2008 |
Phosphorylation of eIF2 directs ATF5 translational control in response to diverse stress conditions. |
uORFs |
| 84 |
2008 |
Role of the dsRNA-dependent protein kinase (PKR) in the attenuation of protein loss from muscle by insulin and insulin-like growth factor-I (IGF-I). |
IGF-I, PIF, PKR |
| 85 |
2007 |
Interferons induce tyrosine phosphorylation of the eIF2alpha kinase PKR through activation of Jak1 and Tyk2. |
IFN, PKR, Tyr |
| 86 |
2007 |
Mechanism of attenuation of angiotensin-II-induced protein degradation by insulin-like growth factor-I (IGF-I). |
I-kappaB, IGF-I, NF-kappaB, PKCalpha, PKR |
| 87 |
2007 |
Nck-1 selectively modulates eIF2alphaSer51 phosphorylation by a subset of eIF2alpha-kinases. |
GCN2, HRI, PERK, PKR |
| 88 |
2007 |
Requirement for protein kinase R in interleukin-1alpha-stimulated effects in cartilage. |
IL-1 |
| 89 |
2007 |
The eukaryotic initiation factor-2 kinase pathway facilitates differential GADD45a expression in response to environmental stress. |
--- |
| 90 |
2006 |
Characterization of the eIF2-associated protein p67 during brain ischemia and reperfusion. |
--- |
| 91 |
2006 |
Expression and purification of the subunits of human translational initiation factor 2 (eIF2): phosphorylation of eIF2 alpha and beta. |
--- |
| 92 |
2006 |
Nck in a complex containing the catalytic subunit of protein phosphatase 1 regulates eukaryotic initiation factor 2alpha signaling and cell survival to endoplasmic reticulum stress. |
ER, SH |
| 93 |
2006 |
The N-terminal lysine residue-rich domain II and the 340-430 amino acid segment of eukaryotic initiation factor 2-associated glycoprotein p67 are the binding sites for the gamma-subunit of eIF2. |
--- |
| 94 |
2006 |
Tyrosine phosphorylation acts as a molecular switch to full-scale activation of the eIF2alpha RNA-dependent protein kinase. |
PKR |
| 95 |
2006 |
Yeast initiator tRNA identity elements cooperate to influence multiple steps of translation initiation. |
--- |
| 96 |
2005 |
eIF2alpha phosphorylation, stress perception, and the shutdown of global protein synthesis in cultured CHO cells. |
--- |
| 97 |
2005 |
Interaction of recombinant human eIF2 subunits with eIF2B and eIF2alpha kinases. |
--- |
| 98 |
2005 |
PERK is responsible for the increased phosphorylation of eIF2alpha and the severe inhibition of protein synthesis after transient global brain ischemia. |
PERK |
| 99 |
2005 |
Phosphorylation of the alpha-subunit of the eukaryotic initiation factor-2 (eIF2alpha) reduces protein synthesis and enhances apoptosis in response to proteasome inhibition. |
ER, MEF |
| 100 |
2005 |
The eIF1A C-terminal domain promotes initiation complex assembly, scanning and AUG selection in vivo. |
TC |
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