| 1 |
2020 |
Genetic responses of inbred chicken lines illustrate importance of eIF2 family and immune-related genes in resistance to Newcastle disease virus. |
dpi, NDV |
| 2 |
2020 |
Roles of the Translation Initiation Factor eIF2alpha Phosphorylation in Cell Structure and Function. |
--- |
| 3 |
2019 |
Structural basis for eIF2B inhibition in integrated stress response. |
--- |
| 4 |
2019 |
The third structural switch in the archaeal translation initiation factor 2 (aIF2) molecule and its possible role in the initiation of GTP hydrolysis and the removal of aIF2 from the ribosome. |
aIF2 |
| 5 |
2018 |
Dietary Intake of Curcumin Improves eIF2 Signaling and Reduces Lipid Levels in the White Adipose Tissue of Obese Mice. |
DAGs, ER, eWAT, NF-kappaB |
| 6 |
2018 |
Identification of di-substituted ureas that prevent growth of trypanosomes through inhibition of translation initiation. |
eIF2alpha |
| 7 |
2018 |
Origins of robustness in translational control via eukaryotic translation initiation factor (eIF) 2. |
eIF, GDI |
| 8 |
2017 |
EIF2S3 Mutations Associated with Severe X-Linked Intellectual Disability Syndrome MEHMO. |
ISR |
| 9 |
2017 |
Novel mechanisms of eIF2B action and regulation by eIF2alpha phosphorylation. |
GEF, ISR, TC |
| 10 |
2017 |
The role of the innate immune response regulatory gene ABCF1 in mammalian embryogenesis and development. |
dpc, ES cells |
| 11 |
2015 |
Eukaryotic elongation factor 2 kinase regulates the cold stress response by slowing translation elongation. |
eEF2, ER |
| 12 |
2013 |
Translation initiation requires cell division cycle 123 (Cdc123) to facilitate biogenesis of the eukaryotic initiation factor 2 (eIF2). |
Cdc123 |
| 13 |
2011 |
eIF2A mediates translation of hepatitis C viral mRNA under stress conditions. |
HCV, IRES |
| 14 |
2010 |
The induction of G2/M cell-cycle arrest and apoptosis by cucurbitacin E is associated with increased phosphorylation of eIF2alpha in leukemia cells. |
--- |
| 15 |
2010 |
Translation control by protein kinase R restricts minute virus of mice infection: role in parvovirus oncolysis. |
dsRNA, MEFs, MVM, PKR |
| 16 |
2009 |
Enhancement of cisplatin cytotoxicity by SAHA involves endoplasmic reticulum stress-mediated apoptosis in oral squamous cell carcinoma cells. |
ER, OSCC, PP1, SAHA |
| 17 |
2009 |
Rapid evolution of protein kinase PKR alters sensitivity to viral inhibitors. |
--- |
| 18 |
2009 |
Tumor suppression by PTEN requires the activation of the PKR-eIF2alpha phosphorylation pathway. |
PKR |
| 19 |
2009 |
[Eukaryotic translation initiation factor 2B and leukoencephalopathy with vanishing white matter]. |
AFT4, ER, UPR, VWM |
| 20 |
2008 |
GCN2-dependent phosphorylation of eukaryotic translation initiation factor-2alpha in Arabidopsis. |
GCN2 |
| 21 |
2008 |
Induction of apoptosis in human cancer cells by candidaspongiolide, a novel sponge polyketide. |
CAN |
| 22 |
2008 |
PERK and PKR: old kinases learn new tricks. |
ER, PKR |
| 23 |
2006 |
Eukaryotic translation initiation factor 3 (eIF3) and eIF2 can promote mRNA binding to 40S subunits independently of eIF4G in yeast. |
eIF3, MFC |
| 24 |
2005 |
Phylogenetic mapping of intron positions: a case study of translation initiation factor eIF2gamma. |
--- |
| 25 |
2005 |
The archaeal eIF2 homologue: functional properties of an ancient translation initiation factor. |
--- |
| 26 |
2004 |
GTP-dependent recognition of the methionine moiety on initiator tRNA by translation factor eIF2. |
--- |
| 27 |
2004 |
Resistance to vesicular stomatitis virus infection requires a functional cross talk between the eukaryotic translation initiation factor 2alpha kinases PERK and PKR. |
MEFs, VSV |
| 28 |
2004 |
Solution structure of human initiation factor eIF2alpha reveals homology to the elongation factor eEF1B. |
--- |
| 29 |
2004 |
Translation reinitiation at alternative open reading frames regulates gene expression in an integrated stress response. |
ATF4, ISR, uORFs |
| 30 |
2003 |
Protein synthesis and endoplasmic reticulum stress can be modulated by the hepatitis C virus envelope protein E2 through the eukaryotic initiation factor 2alpha kinase PERK. |
ER, PERK |
| 31 |
2001 |
Minimum requirements for the function of eukaryotic translation initiation factor 2. |
--- |
| 32 |
2000 |
Conserved sequences in the beta subunit of archaeal and eukaryal translation initiation factor 2 (eIF2), absent from eIF5, mediate interaction with eIF2gamma. |
--- |
| 33 |
2000 |
Defects in tRNA processing and nuclear export induce GCN4 translation independently of phosphorylation of the alpha subunit of eukaryotic translation initiation factor 2. |
hcPUS4 |
| 34 |
2000 |
Recognition of 5'-terminal TAR structure in human immunodeficiency virus-1 mRNA by eukaryotic translation initiation factor 2. |
HIV-1 |
| 35 |
1999 |
Association of protein kinase CK2 with eukaryotic translation initiation factor eIF-2 and with grp94/endoplasmin. |
--- |
| 36 |
1999 |
The beta subunit of eukaryotic translation initiation factor 2 binds mRNA through the lysine repeats and a region comprising the C2-C2 motif. |
--- |
| 37 |
1998 |
Identification and requirement of three ribosome binding domains in dsRNA-dependent protein kinase (PKR). |
ds, PKR, TAR |
| 38 |
1997 |
The gamma(1)34.5 protein of herpes simplex virus 1 complexes with protein phosphatase 1alpha to dephosphorylate the alpha subunit of the eukaryotic translation initiation factor 2 and preclude the shutoff of protein synthesis by double-stranded RNA-activated protein kinase. |
GADD34, PKR |
| 39 |
1996 |
A eukaryotic translation initiation factor 2-associated 67 kDa glycoprotein partially reverses protein synthesis inhibition by activated double-stranded RNA-dependent protein kinase in intact cells. |
--- |
| 40 |
1996 |
Ligand interactions with eukaryotic translation initiation factor 2: role of the gamma-subunit. |
Met |
| 41 |
1995 |
The interferon-inducible protein kinase PKR modulates the transcriptional activation of immunoglobulin kappa gene. |
IFN |
| 42 |
1993 |
A difference in the rate of ribosomal elongation balances the synthesis of eukaryotic translation initiation factor (eIF)-2 alpha and eIF-2 beta. |
eIF |
| 43 |
1993 |
Guanine nucleotide exchange factor for eukaryotic translation initiation factor 2 in Saccharomyces cerevisiae: interactions between the essential subunits GCD2, GCD6, and GCD7 and the regulatory subunit GCN3. |
--- |
| 44 |
1992 |
Phosphorylation of initiation factor 2 alpha by protein kinase GCN2 mediates gene-specific translational control of GCN4 in yeast. |
--- |
| 45 |
1992 |
The suil suppressor locus in Saccharomyces cerevisiae encodes a translation factor that functions during tRNA(iMet) recognition of the start codon. |
--- |
| 46 |
1992 |
Truncated protein phosphatase GLC7 restores translational activation of GCN4 expression in yeast mutants defective for the eIF-2 alpha kinase GCN2. |
--- |
| 47 |
1985 |
The 90-kDa component of reticulocyte heme-regulated eIF-2 alpha (initiation factor 2 alpha-subunit) kinase is derived from the beta subunit of spectrin. |
--- |
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