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Abbreviation : hVDR
Long Form : human vitamin D receptor
No. Year Title Co-occurring Abbreviation
2018 Effects of 2-substitution on 14-epi-19-nortachysterol-mediated biological events: based on synthesis and X-ray co-crystallographic analysis with the human vitamin D receptor. ---
2016 Phosphorylation of Human Retinoid X Receptor alpha at Serine 260 Impairs Its Subcellular Localization, Receptor Interaction, Nuclear Mobility, and 1alpha,25-Dihydroxyvitamin D3-dependent DNA Binding in Ras-transformed Keratinocytes. FRET, hRXR alpha
2016 Synthesis of 2alpha- and 2beta-(3-hydroxypropyl)- 7,8-cis-14-epi-1alpha,25-dihydroxy-19-norvitamin D3 and their biological activity. ---
2016 Vitamin D Analogs with Nitrogen Atom at C2 Substitution and Effect on Bone Formation. ---
2015 Skeletal characterization of an osteoblast-specific vitamin D receptor transgenic (ObVDR-B6) mouse model. WT
2015 Synthesis, metabolism, and biological activity of 2-[3-(tetrazolyl)propyl]-1alpha,25-dihydroxy-19-norvitamin D3. HOS
2014 Synthesis and properties of 14-epi-1alpha,25-dihydroxy-19-nortachysterol and its 2-substituted derivatives. ---
2014 Synthesis of 2alpha-heteroarylalkyl active vitamin d3 with therapeutic effect on enhancing bone mineral density in vivo. HOS
2013 Design and synthesis of 2alpha-(tetrazolylethyl)-1alpha,25-dihydroxyvitamin D3 as a high affinity ligand for vitamin D receptor. HOS, LBD
10  2012 Vitamin D receptor signaling in podocytes protects against diabetic nephropathy. ---
11  2011 A human vitamin D receptor mutant activated by cholecalciferol. ---
12  2011 Design, synthesis, evaluation, and structure of vitamin D analogues with furan side chains. ---
13  2011 Synthesis, structure, and biological activity of des-side chain analogues of 1alpha,25-dihydroxyvitamin D3 with substituents at C18. ---
14  2011 The role of residue C410 on activation of the human vitamin D receptor by various ligands. LBP, LCA, NRs
15  2011 [Prokaryotic expression of human vitamin D receptor (hVDR) and its binding activities to Cd and Pb]. ---
16  2007 Exons and functional regions of the human vitamin D receptor gene around and within the main 1a promoter are well conserved among mammals. ---
17  2007 Transgenic expression of the human Vitamin D receptor (hVDR) in the duodenum of VDR-null mice attenuates the age-dependent decline in calcium absorption. ---
18  2006 Ligand recognition by vitamin D receptor: total alanine scanning mutational analysis of the residues lining the ligand binding pocket of vitamin D receptor. ASMA, LBP, NRs, SCA
19  2006 Nuclear receptor interactions in methotrexate induction of human dehydroepiandrosterone sulfotransferase (hSULT2A1). hCAR, hPXR, SULTs
20  2005 Two single-nucleotide polymorphisms in the human vitamin D receptor promoter change protein-DNA complex formation and are associated with height and vitamin D status in adolescent girls. SNPs
21  2004 Phosphorylation of human vitamin D receptor serine-182 by PKA suppresses 1,25(OH)2D3-dependent transactivation. PKA, RXR
22  2002 Isolation of baculovirus-expressed human vitamin D receptor: DNA responsive element interactions and phosphorylation of the purified receptor. PAP, RXR, VDRE
23  2001 Functionally relevant polymorphisms in the human nuclear vitamin D receptor gene. ---
24  2001 The unique tryptophan residue of the vitamin D receptor is critical for ligand binding and transcriptional activation. hRXR alpha, SRC-1
25  2000 Biochemical evidence for a 170-kilodalton, AF-2-dependent vitamin D receptor/retinoid X receptor coactivator that is highly expressed in osteoblasts. AF-2, RXR, VIP
26  2000 Comparison of the relative effects of 1,24-dihydroxyvitamin D(2) [1, 24-(OH)(2)D(2)], 1,24-dihydroxyvitamin D(3) [1,24-(OH)(2)D(3)], and 1,25-dihydroxyvitamin D(3) [1,25-(OH)(2)D(3)] on selected vitamin D-regulated events in the rat. EMSA, PMCA, VDR/RXR
27  2000 The polymorphic N terminus in human vitamin D receptor isoforms influences transcriptional activity by modulating interaction with transcription factor IIB. TFIIB
28  1999 Vitamin D-dependent suppression of human atrial natriuretic peptide gene promoter activity requires heterodimer assembly. ---
29  1998 Characterization of the activation function-2 domain of the human 1,25-dihydroxyvitamin D3 receptor. AF-2, TFIIB
30  1998 Novel nuclear localization signal between the two DNA-binding zinc fingers in the human vitamin D receptor. ---
31  1997 Mutations in the 1,25-dihydroxyvitamin D3 receptor identifying C-terminal amino acids required for transcriptional activation that are functionally dissociated from hormone binding, heterodimeric DNA binding, and interaction with basal transcription factor IIB, in vitro. TFIIB
32  1996 Human vitamin D receptor-dependent transactivation in Saccharomyces cerevisiae requires retinoid X receptor. RXR, VDREs
33  1996 Transcriptional activation and dimerization functions in the human vitamin D receptor. ---
34  1996 Vitamin D receptor interactions with the murine osteopontin response element. hRXR beta, UV
35  1995 A highly conserved region in the hormone-binding domain of the human vitamin D receptor contains residues vital for heterodimerization with retinoid X receptor and for transcriptional activation. RXR, VDRE
36  1995 Receptor mediated genomic action of the 1,25(OH)2D3 hormone: expression of the human vitamin D receptor in E. coli. RXRs, VDR, VDRE
37  1995 The T-box near the zinc fingers of the human vitamin D receptor is required for heterodimeric DNA binding and transactivation. GR, RXR, VDRE
38  1994 A peptide C-terminal to the second Zn finger of human vitamin D receptor is able to specify nuclear localization. SV40
39  1994 Identification of a vitamin D responsive element in the promoter of the rat cytochrome P450(24) gene. VDREs
40  1994 The C-terminal region of the vitamin D receptor is essential to form a complex with a receptor auxiliary factor required for high affinity binding to the vitamin D-responsive element. RAF, VDRE
41  1993 Phosphorylation of the human vitamin D receptor by protein kinase C. Biochemical and functional evaluation of the serine 51 recognition site. PKCbeta, S51G, S51T, VDRE
42  1993 Purified human vitamin D receptor overexpressed in E. coli and baculovirus systems does not bind 1,25-dihydroxyvitamin D3 hormone efficiently unless supplemented with a rat liver nuclear extract. ---
43  1991 Baculovirus-mediated expression of the human vitamin D receptor. Functional characterization, vitamin D response element interactions, and evidence for a receptor auxiliary factor. BEVS, VDRE