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Abbreviation : i.c.v
Long Form : intracerebroventricular
No. Year Title Co-occurring Abbreviation
2021 7,8-Dihydroxyflavone improves cognitive functions in ICV-STZ rat model of sporadic Alzheimer's disease by reversing oxidative stress, mitochondrial dysfunction, and insulin resistance. 7,8-DHF, AChE, GPx, IDE, LPO, MWM, NOR, PCO, SAD, SOD, STZ
2021 A New Approach to Model Sporadic Alzheimer's Disease by Intracerebroventricular Streptozotocin Injection in APP/PS1 Mice. AD, APP, SAD, STZ
2021 A Specialized Nutritional Formulation Prevents Hippocampal Glial Activation and Memory Impairment Induced by Amyloid-β Oligomers in Mice. AbetaOs, AD, NOR
2021 Abscisic acid interplays with PPARγ receptors and ameliorates diabetes-induced cognitive deficits in rats. ABA, MWM, PPARgamma, STZ
2021 Activation of GPR55 attenuates cognitive impairment and neurotoxicity in a mouse model of Alzheimer's disease induced by Aβ1-42 through inhibiting RhoA/ROCK2 pathway. AD, BACE1, CAT, GPR55, MDA, MWM, NOR, SOD, SYN
2021 Activation of L-type calcium channels and attenuation of oxidative stress are involved in the improving effect of methyl jasmonate on learning and memory and its anxiolytic property in rats. ---
2021 Adeno-associated virus (AAV)-based gene therapy for glioblastoma. AAV, GBM
2021 Adeno-Associated Virus-Mediated Gene Therapy in the Mashlool, Atp1a3Mashl/+, Mouse Model of Alternating Hemiplegia of Childhood. AAV9, AHC
2021 Adenosine monophosphate activated protein kinase (AMPK) is essential for the memory improving effect of adiponectin. AMPK, APN, DM, IRS-1, NOR, PI, STL, STZ, TDC
10  2021 Amentoflavone Ameliorates Memory Deficits and Abnormal Autophagy in Aβ25-35-Induced Mice by mTOR Signaling. Abeta25-35, AD
11  2021 Amyloidogenic, neuroinflammatory and memory dysfunction effects of HIV-1 gp120. HIV-1
12  2021 An optimized intracerebroventricular injection of CD4+ T cells into mice. ---
13  2021 Angiotensin II-induced drinking behavior as a method to verify cannula placement into the cerebral ventricles of mice: An evaluation of its accuracy. Ang II
14  2021 Angiotensin-(1-7) Central Mechanisms After ICV Infusion in Hypertensive Transgenic (mRen2)27 Rats. RAS, SD
15  2021 Antagonism for NPY signaling reverses cognitive behavior defects induced by activity-based anorexia in mice. ABA, AgRP, NOR, NPY
16  2021 Biochemical evaluation of intracerebroventricular rhNAGLU-IGF2 enzyme replacement therapy in neonatal mice with Sanfilippo B syndrome. HS, NAGLU
17  2021 Brain ACE2 activation following brain aminopeptidase A blockade by firibastat in salt-dependent hypertension. ACE2, Ang 1-7, APA, BP, DOCA, MasR
18  2021 Brain angiotensin system: a new promise in the management of epilepsy? AED, Ang II, Bcl-2, Mas, RAS, SMS
19  2021 Brain energy metabolism in intracerebroventricularly administered streptozotocin mouse model of Alzheimer's disease: A 1H-[13C]-NMR study. AD, STZ
20  2021 Brain-derived neurotrophic factor (BDNF) affects the activity of the gonadotrophic axis in sheep. BDNF
21  2021 Cannabidiol efficiently suppressed the acquisition and expression of methamphetamine-induced conditioned place preference in the rat. CBD, CPP, MET
22  2021 Cannabidiol promotes neurogenesis in the dentate gyrus during an abstinence period in rats following chronic exposure to methamphetamine. CBD, DG, METH
23  2021 Central Administration of Angiotensin-(1-7) Improves Vasopressin Impairment and Hypotensive Response in Experimental Endotoxemia. HPA, HR, IL-10, IL-6, LPS, MABP, NE, NO, RAS
24  2021 Central GLP-1 contributes to improved cognitive function and brain glucose uptake after duodenum-jejunum bypass on obese and diabetic rats. CSF, DJB, Exe-9, GLP-1, GLP-1R, GLUT1, KD, LIRA, MWM, pAS160, PET, RYGB, SHAM
25  2021 Central involvement of 5-HT1A receptors in antinociception induced by photobiomodulation in animal model of neuropathic pain. CCI, PBM
26  2021 Central Nervous System Inflammation Induced by Lipopolysaccharide Up-Regulates Hepatic Hepcidin Expression by Activating the IL-6/JAK2/STAT3 Pathway in Mice. LPS
27  2021 Chronic administration of Tat-GluR23Y ameliorates cognitive dysfunction targeting CREB signaling in rats with amyloid beta neurotoxicity. Abeta1-42, AD, ANOVA, CREB, MWM, TTS
28  2021 Chronic Antidiabetic Actions of Leptin: Evidence From Parabiosis Studies for a CNS-Derived Circulating Antidiabetic Factor. CNS, STZ
29  2021 Comparative Effectiveness of Intracerebroventricular, Intrathecal, and Intranasal Routes of AAV9 Vector Administration for Genetic Therapy of Neurologic Disease in Murine Mucopolysaccharidosis Type I. CP, ERT, HSCT, i.n, i.t, IDUA, MPS I
30  2021 Conifer Essential Oils Reversed Amyloid Beta1-42 Action by Modulating BDNF and ARC Expression in The Rat Hippocampus. Abeta1-42, AD, Arc, BDNF, IL-1beta
31  2021 Development of next-generation tumor-homing induced neural stem cells to enhance treatment of metastatic cancers. hiNeuroS-TRAIL, hiNSC, NSCs, TNBC
32  2021 Dihydrolipoic acid enhances autophagy and alleviates neurological deficits after subarachnoid hemorrhage in rats. DHLA, EBI, FJC, LAMP1, SAH, siRNA
33  2021 Drotaverine Inhibitor of PDE4: Reverses the Streptozotocin Induced Alzheimer's Disease in Mice. AD
34  2021 Effect of Neuropeptide S Administration on Ultrasonic Vocalizations and Behaviour in Rats with Low vs. High Exploratory Activity. NPS, USV
35  2021 Effects of intracerebroventricularly administered opioid peptide antagonists on tissue glycogen levels in rats after exercise ---
36  2021 Effects of intraperitoneal and intracerebroventricular injection of cinnamaldehyde and yohimbine on blood glucose and serum insulin concentrations in ketamine-xylazine induced acute hyperglycemia. i.p
37  2021 Effects of Low-Intensity Transcranial Pulsed Ultrasound Treatment in a Model of Alzheimer's Disease. AD, LIPUS
38  2021 Effects of Pretreatment With Ginseng Extract on Dopamine D2 Receptor Analgesia. aCSF, i.p
39  2021 Effects of vanillic acid on Aβ1-40-induced oxidative stress and learning and memory deficit in male rats. AD, MDA, MWM, NOR, PAL, TAC, TOS, VA
40  2021 Electro-Acupuncture Attenuates Chronic Stress Responses via Up-Regulated Central NPY and GABA A Receptors in Rats. CCS, CRF, EA, GABA, HPA, NPY, ST-36
41  2021 Everolimus: A potential therapeutic agent targeting PI3K/Akt pathway in brain insulin system dysfunction and associated neurobehavioral deficits. ---
42  2021 Examining the non-spatial pretraining effect on a water maze spatial learning task in rats treated with multiple intracerebroventricular (ICV) infusions of propionic acid: Contributions to a rodent model of ASD. ASD, MWM, NSP, PPA
43  2021 Exogenous orexin-A downregulates luteinizing hormone secretory activity in prepubertal female rats. CSF, Lhb
44  2021 FGF-2 suppresses neuronal autophagy by regulating the PI3K/Akt pathway in subarachnoid hemorrhage. EBI, FGF-2, SAH, SD
45  2021 G-Protein-Gated Inwardly Rectifying Potassium (Kir3/GIRK) Channels Govern Synaptic Plasticity That Supports Hippocampal-Dependent Cognitive Functions in Male Mice. GIRK, GPCRs, HFS, LTD, LTP, TQ
46  2021 Gastroprotective effect of fluvoxamine and ondansetron on stress-induced gastric ulcers in mice. i.p, WIRS
47  2021 Highly efficient neuronal gene knockout in vivo by CRISPR-Cas9 via neonatal intracerebroventricular injection of AAV in mice. CNS, sgRNA
48  2021 Hypothalamic long noncoding RNA AK044061 is involved in the development of dietary obesity in mice. AgRP, ARC, DIO, lncRNAs, RIP
49  2021 Impact of sex differences on thrombin-induced hydrocephalus and white matter injury: the role of neutrophils. IVH
50  2021 Importance of extracellular vesicle secretion at the blood-cerebrospinal fluid interface in the pathogenesis of Alzheimer's disease. AbetaO, AD, CPE, CSF, EVs
51  2021 In vivo uptake of a fluorescent conjugate of melanin-concentrating hormone in the rat brain. MCH, PAO
52  2021 Infusion of hESC derived Immunity-and-matrix regulatory cells improves cognitive ability in early-stage AD mice. AD, GMP, hESC, IMRCs
53  2021 Injection of galanin into the dorsal hippocampus impairs emotional memory independent of 5-HT1A receptor activation. PA, s.c
54  2021 Interconnection between Adrenergic and Dopaminergic Systems in Feeding Behavior in Neonatal Chicks. DA, DAergic, NA
55  2021 Interleukin-1β mediates alterations in mitochondrial fusion/fission proteins and memory impairment induced by amyloid-β oligomers. AbetaOs, AD, IL-1, IL-1beta, IL-1R, Mdivi-1
56  2021 Intracerebroventricular administration of α-melanocyte-stimulating hormone (α-MSH) enhances thigmotaxis and induces anxiety-like behavior in the goldfish Carassius auratus. alpha-MSH, BW, CBR, MC4R
57  2021 Intracerebroventricular injection of propranolol blocked analgesic and neuroprotective effects of resveratrol following L5 spinal nerve ligation in rat. CAT, NCV, SNL, SOD
58  2021 Intracranial delivery of AAV9 gene therapy partially prevents retinal degeneration and visual deficits in CLN6-Batten disease mice. CSF
59  2021 Involvement of neurosteroids in the control of hypothalamic-pituitary-adrenal axis activity in pregnant sheep under basal and stressful conditions. AL, CRH, HPA
60  2021 Korean traditional herbal formula Soshiho-tang attenuates memory impairment and neuronal damage in mice with amyloid-beta-induced Alzheimer's disease. AChE, AD, MWM, PAT, SST
61  2021 Leptin and Melanocortin Signaling Mediates Hypertension in Offspring From Female Rabbits Fed a High-Fat Diet During Gestation and Lactation. alpha-MSH, BDNF, INSR, mHFD, RSNA, VMH
62  2021 Leptin receptor expression in the dorsomedial hypothalamus stimulates breathing during NREM sleep in db/db mice. DMH, OHS, OSA
63  2021 Leptin, Acting at Central Level, Increases FGF21 Expression in White Adipose Tissue via PPARβ/δ. eWAT, i.p
64  2021 Liraglutide Has Anti-Inflammatory and Anti-Amyloid Properties in Streptozotocin-Induced and 5xFAD Mouse Models of Alzheimer's Disease. AD, DM, i.p, IRBS, LIR, SAD, STZ
65  2021 MCRT, a multifunctional ligand of opioid and neuropeptide FF receptors, attenuates neuropathic pain in spared nerve injury model. i.pl, NPFF, SNI
66  2021 Mediatory role of the dopaminergic system through D1 receptor on glycine-induced hypophagia in neonatal broiler-type chickens. ---
67  2021 Mesenchymal Stem Cell (MSC)-Derived Extracellular Vesicles Protect from Neonatal Stroke by Interacting with Microglial Cells. i.n, MSC, MSC-sEV
68  2021 MicroRNA-138-5p Regulates Hippocampal Neuroinflammation and Cognitive Impairment by NLRP3/Caspase-1 Signaling Pathway in Rats. ELISA, LPS, miR-138-5p, MWM, qRT-PCR
69  2021 Minimally Invasive Nasal Depot (MIND) technique for direct BDNF AntagoNAT delivery to the brain. AT, BBB, BDNF, CNS, ENT, i.t, MIND
70  2021 Mirogabalin activates the descending noradrenergic system by binding to the α2δ-1 subunit of voltage-gated Ca2+ channels to generate analgesic effects. i.p, i.t
71  2021 Modulation of Glucose Production by Central Insulin Requires IGF-1 Receptors in AgRP Neurons. GIR, HGP, IGF-1, IGF-1Rs, InsRs
72  2021 Neuroinflammation decreased hippocampal microtubule dynamics in the acute behavioral deficits induced by intracerebroventricular injection of lipopolysaccharide in male adult rats. FST, OFT, SPT
73  2021 Neuropeptide Y modifies a part of diencephalic catecholamine but not indolamine metabolism in chicks depending on feeding status. HVA, NPY
74  2021 Neuroprotective effects of dexpanthenol on streptozotocin-induced neuronal damage in rats. AD, CA1, CA3, ChAT, PAL, TNF-alpha
75  2021 Nicotinamide Ameliorates Amyloid Beta-Induced Oxidative Stress-Mediated Neuroinflammation and Neurodegeneration in Adult Mouse Brain. AD, NAM, ROS
76  2021 NLRP3 inflammasome activation increases brain oxidative stress after transient global cerebral ischemia in rats. CAT, I/R, MPO, N/N, SOD
77  2021 Olanzapine-induced insulin resistance may occur via attenuation of central KATP channel-activation. CNS
78  2021 Ouabain induces memory impairment and alter the BDNF signaling pathway in an animal model of bipolar disorder: Cognitive and neurochemical alterations in BD model. aCSF, IA, NOR
79  2021 Oxytocin prevents cue-induced reinstatement of oxycodone seeking: Involvement of DNA methylation in the hippocampus. 5hmC, 5mC, CPP, TETs
80  2021 Participation of Central Muscarinic Receptors on the Nervous Form of Chagas Disease in Mice Infected via Intracerebroventricular with Colombian Trypanosoma cruzi Strain. CNS, i.p, mAChR
81  2021 Platelet-derived growth factor (PDGF)-BB protects dopaminergic neurons via activation of Akt/ERK/CREB pathways to upregulate tyrosine hydroxylase. PD, PDGF, TH
82  2021 Protective effect of chronic administration of pelargonidin on neuronal apoptosis and memory process in amyloid-beta-treated rats. AD, NOR, PG
83  2021 Protective effects of intracerebroventricular adiponectin against olfactory impairments in an amyloid β1-42 rat model. Abeta1-42, AD, APN, DG, HIPP, Iba1, NeuN, OB
84  2021 Reduced Cerebral Glucose Uptake in an Alzheimer's Rat Model With Glucose-Weighted Chemical Exchange Saturation Transfer Imaging. AD, DTI, GCE, glucoCEST, Ins, MRS
85  2021 Reduction in Nesfatin-1 Levels in the Cerebrospinal Fluid and Increased Nigrostriatal Degeneration Following Ventricular Administration of Anti-nesfatin-1 Antibody in Mice. BDNF, CSF, ELISA, HPLC, MPTP, PD, SNpc, TEM
86  2021 Roflumilast and tadalafil improve learning and memory deficits in intracerebroventricular Aβ1-42 rat model of Alzheimer's disease through modulations of hippocampal cAMP/cGMP/BDNF signaling pathway. AD, MWM, NOR, p-Tau, PDE, RFM, TDF
87  2021 Role of hypothalamic MAPK/ERK signaling and central action of FGF1 in diabetes remission. FGF1, MAPK
88  2021 Role of protein tyrosine phosphatase 1B inhibitor in central insulin resistance and associated cognitive deficits. PTP1B
89  2021 Selective MOR activity of DAPEA and Endomorphin-2 analogues containing a (R)-γ-Freidinger lactam in position two. Agl, EM-2
90  2021 Sex differences and similarities in the neuroimmune response to central administration of poly I:C. ---
91  2021 Single intracerebroventricular progranulin injection adversely affects the blood-brain barrier in experimental traumatic brain injury. PGRN, rPGRN, TBI
92  2021 Stamina-Enhancing Effects of Human Adipose-Derived Stem Cells. BDNF, hADSCs, PND
93  2021 Stimulatory, but not anxiogenic, doses of caffeine act centrally to activate interscapular brown adipose tissue thermogenesis in anesthetized male rats. IBAT
94  2021 Supplementation with ribonucleotide-based ingredient (Ribodiet®) lessens oxidative stress, brain inflammation, and amyloid pathology in a murine model of Alzheimer. AD
95  2021 Sustained Hippocampal Neural Plasticity Questions the Reproducibility of an Amyloid-β-Induced Alzheimer's Disease Model. Abeta42, AD
96  2021 Synergistic enhancing-memory effect of D-serine and RU360, a mitochondrial calcium uniporter blocker in rat model of Alzheimer's disease. BDNF, CREB, DCS, MCU, MWM, SPL
97  2021 TAK1 mediates neuronal pyroptosis in early brain injury after subarachnoid hemorrhage. BBB, EBI, NOD, oxyHb, OZ, ROS, SAH, siRNA, TAK1
98  2021 The AMPK-mTOR signaling pathway is involved in regulation of food intake in the hypothalamus of stressed chickens. DEX, GCs, LKB1, NPY
99  2021 The anorexigenic effect of neuropeptide AF in Japanese quail, Coturnix japonica, is associated with activation of the melanocortin system. NPAF
100  2021 The avian central roles of alpha and beta oestrogen receptors on food intake. alphaER