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Total Number of Papers: 239
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| Abbreviation |
: mEH |
| Long Form |
: microsomal epoxide hydrolase |
|
| No. |
Year |
Title |
Co-occurring Abbreviation |
| 1 |
2021 |
Ibuprofen alters epoxide hydrolase activity and epoxy-oxylipin metabolites associated with different metabolic pathways in murine livers. |
COX, NSAIDs, sEH |
| 2 |
2021 |
Missense Genetic Polymorphisms of Microsomal (EPHX1) and Soluble Epoxide Hydrolase (EPHX2) and Their Relation to the Risk of Large Artery Atherosclerotic Ischemic Stroke in a Turkish Population. |
EETs, sEH, SNPs |
| 3 |
2021 |
Relative Importance of Soluble and Microsomal Epoxide Hydrolases for the Hydrolysis of Epoxy-Fatty Acids in Human Tissues. |
EH3, EHs, EpFAs, sEH |
| 4 |
2021 |
Role of Epoxide Hydrolases and Cytochrome P450s on Metabolism of KZR-616, a First-in-Class Selective Inhibitor of the Immunoproteasome. |
sEH |
| 5 |
2020 |
Development of potent inhibitors of the human microsomal epoxide hydrolase. |
--- |
| 6 |
2019 |
Association of Activity Altering Genotypes - Tyr113His and His139Arg in Microsomal Epoxide Hydrolase Enzyme with Esophageal Squamous Cell Carcinoma. |
ESCC |
| 7 |
2019 |
Hip To Be Square: Oxetanes as Design Elements To Alter Metabolic Pathways. |
--- |
| 8 |
2019 |
Protein kinase Cdelta mediates methamphetamine-induced dopaminergic neurotoxicity in mice via activation of microsomal epoxide hydrolase. |
MA, PKCdelta, WT |
| 9 |
2018 |
Aflatoxin B1 metabolism: Regulation by phase I and II metabolizing enzymes and chemoprotective agents. |
AFAR, AFB1, AFBO, GST |
| 10 |
2017 |
Evidence for a complex formation between CYP2J5 and mEH in living cells by FRET analysis of membrane protein interaction in the endoplasmic reticulum (FAMPIR). |
CYP, FAMPIR |
| 11 |
2017 |
Microsomal epoxide hydrolase gene polymorphisms and susceptibility to prostate cancer: A systematic review. |
PCs |
| 12 |
2017 |
Oxetane Substrates of Human Microsomal Epoxide Hydrolase. |
sEH |
| 13 |
2016 |
Genetic enhancement of microsomal epoxide hydrolase improves metabolic detoxification but impairs cerebral blood flow regulation. |
CBV, DHETs, EETs, fMRI |
| 14 |
2016 |
Modulatory effects of catechin hydrate against genotoxicity, oxidative stress, inflammation and apoptosis induced by benzo(a)pyrene in mice. |
PAH |
| 15 |
2016 |
Naphthalene cytotoxicity in microsomal epoxide hydrolase deficient mice. |
NA, WT |
| 16 |
2015 |
Are polymorphisms in metabolism protective or a risk for reduced white blood cell counts in a Chinese population with low occupational benzene exposures? |
CYP2E1, GSTP1, PCR, RFLP, WBCs |
| 17 |
2015 |
Association of Functional Variants of Phase I and II Genes with Chronic Obstructive Pulmonary Disease in a Serbian Population. |
COPD, GST |
| 18 |
2015 |
Dietary Doses of Sulforaphane Affect Hepatic Drug Metabolizing Enzymes in Spontaneously Hypertensive Rats. |
DME, SF, SHR |
| 19 |
2015 |
Meta-analysis of microsomal epoxide hydrolase gene polymorphism and the risk of breast carcinoma. |
CIs, ORs |
| 20 |
2015 |
Modulation of human cytochrome P450 1A1-mediated oxidation of benzo[a]pyrene by NADPH:cytochrome P450 oxidoreductase and cytochrome b5. |
BaP, HPLC |
| 21 |
2015 |
Transcription of the Human Microsomal Epoxide Hydrolase Gene (EPHX1) Is Regulated by PARP-1 and Histone H1.2. Association with Sodium-Dependent Bile Acid Transport. |
PARP-1 |
| 22 |
2014 |
Hepatic bile acid metabolism and expression of cytochrome P450 and related enzymes are altered in Bsep (-/-) mice. |
CA |
| 23 |
2014 |
Hepatitis B spliced protein (HBSP) promotes the carcinogenic effects of benzo [alpha] pyrene by interacting with microsomal epoxide hydrolase and enhancing its hydrolysis activity. |
BPDE, HBsAg, HBSP, HBV, HCC, HPLC |
| 24 |
2014 |
Impact of epoxide hydrolase 1 polymorphisms on lung cancer susceptibility in Asian populations. |
--- |
| 25 |
2014 |
Intronic DNA elements regulate Nrf2 chemical responsiveness of the human microsomal epoxide hydrolase gene (EPHX1) through a far upstream alternative promoter. |
ARE, SFN, tBHQ |
| 26 |
2014 |
Localization of cytochrome P450 and related enzymes in adult rat testis and downregulation by estradiol and bisphenol A. |
HSD3B |
| 27 |
2014 |
Try113His and His139Arg polymorphisms in the microsomal epoxide hydrolase gene are not associated with risk of breast cancer. |
CIs, ORs |
| 28 |
2013 |
Association between environmental tobacco smoke exposure and lung cancer susceptibility: modification by antioxidant enzyme genetic polymorphisms. |
ETS, OR |
| 29 |
2013 |
Discovery of soluble epoxide hydrolase inhibitors from natural products. |
sEH |
| 30 |
2013 |
mEH Tyr113His polymorphism and the risk of ovarian cancer development. |
CIs, ORs |
| 31 |
2013 |
Meta-analysis of microsomal epoxide hydrolase gene polymorphism and risk of hepatocellular carcinoma. |
HCC, ORs |
| 32 |
2013 |
Oxidation of carcinogenic benzo[a]pyrene by human and rat cytochrome P450 1A1 and its influencing by cytochrome b5 - a comparative study. |
BaP, HPLC |
| 33 |
2013 |
Transcription of the human microsomal epoxide hydrolase gene (EPHX1) is regulated by an HNF-4alpha/CAR/RXR/PSF complex. |
PSF |
| 34 |
2012 |
Development of monoclonal antibodies to human microsomal epoxide hydrolase and analysis of "preneoplastic antigen"-like molecules. |
ER |
| 35 |
2012 |
EPHX1 polymorphisms do not modify esophageal carcinoma susceptibility in Dutch Caucasians. |
EAC, EC |
| 36 |
2012 |
Low microsomal epoxide hydrolase expression is associated with bladder carcinogenesis and recurrence. |
--- |
| 37 |
2012 |
Xenobiotic metabolizing gene variants and renal cell cancer: a multicenter study. |
COMT, RCC, UGT |
| 38 |
2011 |
Association of CYP2E1, GST and mEH genetic polymorphisms with urinary acrylamide metabolites in workers exposed to acrylamide. |
AA, AAMA, CYP2E1, GA, PCR |
| 39 |
2011 |
Benzo(a)pyrene-induced pulmonary inflammation, edema, surfactant dysfunction, and injuries in rats: alleviation by farnesol. |
BALF, BW, GST, LDH, NO |
| 40 |
2011 |
Chromosomal damage and polymorphisms of metabolic genes among 1, 3-butadiene-exposed workers in a matched study in China. |
BD, CBMN, CI, CYP2E1, FR, GST, MNi, NPBs, PCR |
| 41 |
2011 |
Colorectal polyp type and the association with charred meat consumption, smoking, and microsomal epoxide hydrolase polymorphisms. |
HPs, OR |
| 42 |
2011 |
Comparison of styrene oxide enantiomers for hepatotoxic and pneumotoxic effects in microsomal epoxide hydrolase-deficient mice. |
SO |
| 43 |
2011 |
Development of fluorescent substrates for microsomal epoxide hydrolase and application to inhibition studies. |
--- |
| 44 |
2011 |
Effects of poloxamer 407-induced hyperlipidemia on the pharmacokinetics of carbamazepine and its 10,11-epoxide metabolite in rats: Impact of decreased expression of both CYP3A1/2 and microsomal epoxide hydrolase. |
AUC, CBZ, CBZ-D, CBZ-E |
| 45 |
2011 |
Genetic polymorphisms of glutathione-S-transferase and microsomal epoxide hydrolase in egyptian acquired aplastic anemia patients. |
AA, GST |
| 46 |
2011 |
Genetically lowered microsomal epoxide hydrolase activity and tobacco-related cancer in 47,000 individuals. |
--- |
| 47 |
2011 |
Ovarian expressed microsomal epoxide hydrolase: role in detoxification of 4-vinylcyclohexene diepoxide and regulation by phosphatidylinositol-3 kinase signaling. |
DMBA, PI3K, PND, VCD, VCH |
| 48 |
2011 |
Polymorphisms in the microsomal epoxide hydrolase gene: role in lung cancer susceptibility and prognosis. |
PCR-RFLP |
| 49 |
2010 |
Functional expression and magnetic nanoparticle-based Immobilization of a protein-engineered marine fish epoxide hydrolase of Mugil cephalus for enantioselective hydrolysis of racemic styrene oxide. |
--- |
| 50 |
2010 |
Metabolism and toxicity of styrene in microsomal epoxide hydrolase-deficient mice. |
--- |
| 51 |
2010 |
Microsomal epoxide hydrolase expression in the endometrial uterine corpus is regulated by progesterone during the menstrual cycle. |
ERalpha, MPA, PR |
| 52 |
2009 |
Distribution of soluble and microsomal epoxide hydrolase in the mouse brain and its contribution to cerebral epoxyeicosatrienoic acid metabolism. |
DHETs, EETs, sEH |
| 53 |
2009 |
Genetic polymorphisms of smoking-related carcinogen detoxifying enzymes and head and neck cancer susceptibility. |
GSTs, SCCHN, UDP |
| 54 |
2009 |
Influence of some detoxification enzyme polymorphisms on cytogenetic biomarkers between individuals exposed to very low doses of 1,3-butadiene. |
SCE |
| 55 |
2009 |
Mammalian epoxide hydrolases in xenobiotic metabolism and signalling. |
sEH |
| 56 |
2009 |
Role of microsomal epoxide hydrolase in methamphetamine-induced drug dependence in mice. |
CYP, DA, METH, WT |
| 57 |
2008 |
Development of metabolically stable inhibitors of Mammalian microsomal epoxide hydrolase. |
--- |
| 58 |
2008 |
Differential subcellular distribution and colocalization of the microsomal and soluble epoxide hydrolases in cultured neonatal rat brain cortical astrocytes. |
GFAP, sEH |
| 59 |
2008 |
Effect of CYP2E1 gene deletion in mice on expression of microsomal epoxide hydrolase in response to VCD exposure. |
CYP2E1, DMBA, VCD, VCH, VCM |
| 60 |
2008 |
Expression of ovarian microsomal epoxide hydrolase and glutathione S-transferase during onset of VCD-induced ovotoxicity in B6C3F(1) mice. |
GST, PND4, VCD |
| 61 |
2008 |
Genetic effects and biotoxicity monitoring of occupational styrene exposure. |
CAs, IARC, MA, MN, PGA, SCEs, SCGE, SO |
| 62 |
2008 |
Microsomal epoxide hydrolase deletion enhances tyrosine hydroxylase phosphorylation in mice after MPTP treatment. |
KO, PD, pSer31, TH, WT |
| 63 |
2008 |
Microsomal epoxide hydrolase genotypes and the risk for head and neck cancer. |
--- |
| 64 |
2008 |
Schisandra fructus extract ameliorates doxorubicin-induce cytotoxicity in cardiomyocytes: altered gene expression for detoxification enzymes. |
CPT-1, DOX, GSTs, HO-1, ROS, SFE |
| 65 |
2008 |
The 3,4-oxide is responsible for the DNA binding of benzo[ghi]perylene, a polycyclic aromatic hydrocarbon without a "classic" bay-region. |
3,4,11,12-bisoxide, BghiP, PAH |
| 66 |
2007 |
Association between allelic polymorphisms of metabolizing enzymes (CYP 1A1, CYP 1A2, CYP 2E1, mEH) and occurrence of colorectal cancer in Hungary. |
HAs, OR, PAHs, PCR, RFLP |
| 67 |
2007 |
Associations between smoking, polymorphisms in polycyclic aromatic hydrocarbon (PAH) metabolism and conjugation genes and PAH-DNA adducts in prostate tumors differ by race. |
GST, PAH |
| 68 |
2007 |
Autoantibody response to microsomal epoxide hydrolase in hepatitis C and A. |
--- |
| 69 |
2007 |
Cytochrome P4501A1 and microsomal epoxide hydrolase gene polymorphisms: gene-environment interaction and risk of prostate cancer. |
PCa, PCR/RFLP |
| 70 |
2007 |
Genetic polymorphism and gene expression of microsomal epoxide hydrolase in non-small cell lung cancer. |
NSCLC, PCR, RT-PCR |
| 71 |
2007 |
involvement of microsomal epoxide hydrolase enzyme in ovotoxicity caused by 7,12-dimethylbenz[a]anthracene. |
DMBA, PND |
| 72 |
2007 |
p53 and ATM/ATR regulate 7,12-dimethylbenz[a]anthracene-induced immunosuppression. |
ATM, ATR, DMBA, DMBA-DE |
| 73 |
2007 |
PAH-DNA adducts in a Chinese population: relationship to PAH exposure, smoking and polymorphisms of metabolic and DNA repair genes. |
ERCC2 |
| 74 |
2006 |
Acute effects of novel selenazolidines on murine chemoprotective enzymes. |
BSCA, Gsts, MSCA, OSCA, PhSCA, SCA, Tr, UGTs |
| 75 |
2006 |
Cloning, expression and enantioselective hydrolytic catalysis of a microsomal epoxide hydrolase from a marine fish, Mugil cephalus. |
RACE |
| 76 |
2006 |
Determinants of the variability of aflatoxin-albumin adduct levels in Ghanaians. |
AA, GSTs, HCC, HCV, HVB, SNPs |
| 77 |
2006 |
Detoxification of olefinic epoxides and nucleotide excision repair of epoxide-mediated DNA damage: Insights from animal models examining human sensitivity to 1,3-butadiene. |
BD, BER, NER |
| 78 |
2006 |
Expression of microsomal epoxide hydrolase is elevated in Alzheimer's hippocampus and induced by exogenous beta-amyloid and trimethyl-tin. |
AD |
| 79 |
2006 |
Genetic polymorphisms of microsomal epoxide hydroxylase and glutathione S-transferases M1, T1 and P1, interactions with smoking, and risk for esophageal (Barrett) adenocarcinoma. |
BE, CI, EADC, GERD, GST, OR |
| 80 |
2006 |
Hepatic chemoprotective enzyme responses to 2-substituted selenazolidine-4(R)-carboxylic acids. |
GPx, GST, i.g, i.p, NQO, SCAs, TR, UGT |
| 81 |
2006 |
Inhibition of benzo[a]pyrene-activating enzymes and DNA binding in human bronchial epithelial BEAS-2B cells by methoxylated flavonoids. |
5,7-DMF, BaP, PAHs, RV |
| 82 |
2006 |
Noninvasive identification of interindividual variation in xenobiotic-metabolizing enzymes: implications for cancer epidemiology and biomarker studies. |
GST, H139R, HWE, PCR, RFLP, SNP, XMEs |
| 83 |
2006 |
The role of intracellular signaling in insulin-mediated regulation of drug metabolizing enzyme gene and protein expression. |
GST, MAPK, mTOR, p70S6 kinase, PKB, RTK |
| 84 |
2005 |
Common genetic variants of microsomal epoxide hydrolase affect warfarin dose requirements beyond the effect of cytochrome P450 2C9. |
GGCX, GSTA1 |
| 85 |
2005 |
Epoxide hydrolase and CYP2C9 polymorphisms, cigarette smoking, and risk of colorectal carcinoma in the Nurses' Health Study and the Physicians' Health Study. |
CYP2C9, NHS, PAHs, PHS |
| 86 |
2005 |
Haplotype structures of EPHX1 and their effects on the metabolism of carbamazepine-10,11-epoxide in Japanese epileptic patients. |
CBZ-Diol, CBZ-epoxide, SNPs |
| 87 |
2005 |
Microsomal biotransformation of benzo[ghi]perylene, a mutagenic polycyclic aromatic hydrocarbon without a "classic" bay region. |
BaP, BghiP, PAH |
| 88 |
2005 |
The association between microsomal epoxide hydrolase genotypes and esophageal squamous-cell-carcinoma in Taiwan: interaction between areca chewing and smoking. |
ESCC |
| 89 |
2005 |
Use of genetically modified mouse models to assess pathways of benzene-induced bone marrow cytotoxicity and genotoxicity. |
HSC, NQO1 |
| 90 |
2004 |
Benzo(a)pyrene diolepoxide (BPDE)-DNA adduct levels in leukocytes of smokers in relation to polymorphism of CYP1A1, GSTM1, GSTP1, GSTT1, and mEH. |
BPDE, CYP1A1, GSTM1, GSTP1 |
| 91 |
2004 |
CCAAT/enhancer-binding protein alpha (C/EBPalpha) activates transcription of the human microsomal epoxide hydrolase gene (EPHX1) through the interaction with DNA-bound NF-Y. |
NF-Y |
| 92 |
2004 |
Effect of Fe(2)O(3) on the capacity of benzo(a)pyrene to induce polycyclic aromatic hydrocarbon-metabolizing enzymes in the respiratory tract of Sprague-Dawley rats. |
CYP1A1, EROD, PAHs |
| 93 |
2004 |
Epoxide hydrolase polymorphisms, cigarette smoking and risk of colorectal adenoma in the Nurses' Health Study and the Health Professionals Follow-up Study. |
CI, HPFS, NHS, RR |
| 94 |
2004 |
Functional protein-protein interaction of drug metabolizing enzymes. |
UGT |
| 95 |
2004 |
Induction of gene expression of xenobiotic metabolism enzymes and ABC-transport proteins by PAH and a reconstituted PAH mixture in human Caco-2 cells. |
ABC, PAH, SULT, UGT1A6 |
| 96 |
2004 |
Microsomal epoxide hydrolase, endotoxin, and lung function decline in cotton textile workers. |
SE |
| 97 |
2004 |
Regulation of human microsomal epoxide hydrolase gene (EPHX1) expression by the transcription factor GATA-4. |
--- |
| 98 |
2004 |
Relationship between polymorphisms of genes encoding microsomal epoxide hydrolase and glutathione S-transferase P1 and chronic obstructive pulmonary disease. |
BMI, COPD, GST, GSTP1, OR, PCR-RFLP |
| 99 |
2004 |
Skin and salivary gland carcinogenicity of 7,12-dimethylbenz[a]anthracene is equivalent in the presence or absence of aryl hydrocarbon receptor. |
AhR, DMBA, PAH |
| 100 |
2004 |
The telltale structures of epoxide hydrolases. |
EH, sEH |
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