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Abbreviation : mGluR1
Long Form : metabotropic glutamate receptor 1
No. Year Title Co-occurring Abbreviation
2019 Activation of mGluR1 Mediates C1q-Dependent Microglial Phagocytosis of Glutamatergic Synapses in Alzheimer's Rodent Models. AD, FMRP
2019 Perinatal exposure to fluoxetine increases anxiety- and depressive-like behaviours and alters glutamatergic markers in the prefrontal cortex and hippocampus of male adolescent rats: A comparison between Sprague-Dawley rats and the Wistar-Kyoto rat model of depression. mGluR5, PSD-95
2019 Pharmacological Modulation of Endogenous Opioid Activity to Attenuate Neuropathic Pain in Rats. mERalpha, SNL
2019 Stepwise activation of a class C GPCR begins with millisecond dimer rearrangement. GPCRs, TM
2019 TAT-mGluR1 Attenuation of Neuronal Apoptosis through Prevention of MGluR1alpha Truncation after Experimental Subarachnoid Hemorrhage. SAH, TAT
2018 AgRP/NPY Neuron Excitability Is Modulated by Metabotropic Glutamate Receptor 1 During Fasting. DHPG
2018 Anticancer effect of HOTTIP regulates human pancreatic cancer via the metabotropic glutamate receptor 1 pathway. mTOR, PI3K
2018 Comparison of the role of metabotropic glutamate receptor subtype 1 in developmental refinement of neuronal connectivity between the cerebellum and the sensory thalamus. CF, TC
2018 Dopamine neuron glutamate cotransmission evokes a delayed excitation in lateral dorsal striatal cholinergic interneurons. dSTR, SN
10  2018 Expression levels of long non-coding RNA HOXA distal transcript antisense RNA and metabotropic glutamate receptor 1 in pancreatic carcinoma, and their prognostic values. HOTTIP, lncRNAs
11  2018 Gender-Related Hippocampal Proteomics Study from Young Rats After Chronic Unpredicted Mild Stress Exposure. CUMS, F-C, M-D, NR2B
12  2018 Hippocampal mGluR1-dependent long-term potentiation requires NAADP-mediated acidic store Ca2+ signaling. LTD, LTP, NAADP, TPCs
13  2018 Knockdown of RTN1-C attenuates traumatic neuronal injury through regulating intracellular Ca2+ homeostasis. ER, RTNs, STIM1, TBI, TG, TNI
14  2018 Long-term clinical follow-up of a patient with non-paraneoplastic cerebellar ataxia associated with anti-mGluR1 autoantibodies. ---
15  2018 mGluR1-Dependent Long Term Depression in Rodent Midbrain Dopamine Neurons Is Regulated by Neuregulin 1/ErbB Signaling. DA, LTD, NRG1, SNpc
16  2018 Riluzole Inhibits Proliferation, Migration and Cell Cycle Progression and Induces Apoptosis in Tumor Cells of Various Origins. ALS
17  2018 The GluN1/GluN2B NMDA receptor and metabotropic glutamate receptor 1 negative allosteric modulator has enhanced neuroprotection in a rat subarachnoid hemorrhage model. NAM, NMDA, SAH
18  2018 The Impact and Mechanism of Methylated Metabotropic Glutamate Receptors 1 and 5 in the Hippocampus on Depression-Like Behavior in Prenatal Stress Offspring Rats. FST, mGluR5, OFT, OR, PS, SPT
19  2018 The neurotoxicity induced by PM2.5 might be strongly related to changes of the hippocampal tissue structure and neurotransmitter levels. NMDAR
20  2018 TNF-alpha increases the intrinsic excitability of cerebellar Purkinje cells through elevating glutamate release in Bergmann Glia. AAV, BG, PCs, TNF-alpha
21  2017 A positive feedback loop linking enhanced mGluR function and basal calcium in spinocerebellar ataxia type 2. EPSCs, PNs, SCA2
22  2017 Cardiac mGluR1 metabotropic receptors in cardioprotection. PostC
23  2017 Dominant Mutations in GRM1 Cause Spinocerebellar Ataxia Type 44. ---
24  2017 Effects of Group I metabotropic glutamate receptor antagonists on sensitivity to reinforcer magnitude and delayed reinforcement in a delay-discounting task in rats: Contribution of delay presentation order. ---
25  2017 Estrogens synthesized and acting within a spinal oligomer suppress spinal endomorphin 2 antinociception: ebb and flow over the rat reproductive cycle. EM2, mERs, MOR
26  2017 In Vivo Monitoring for Regional Changes of Metabotropic Glutamate Receptor Subtype 1 (mGluR1) in Pilocarpine-Induced Epileptic Rat Brain by Small-Animal PET. PET, PISE
27  2017 Modulatory effects of Ampicillin/Sulbactam on glial glutamate transporters and metabotropic glutamate receptor 1 as well as reinstatement to cocaine-seeking behavior. AMP/SUL, CPP, dmPFC, GLT-1, NAc
28  2017 Molecular mechanisms of group I metabotropic glutamate receptor mediated LTP and LTD in basolateral amygdala in vitro. BLA, DHPG, LTD, LTP, PKC, PLC, TBS
29  2017 Plasticity of Signaling by Spinal Estrogen Receptor alpha, kappa-Opioid Receptor, and Metabotropic Glutamate Receptors over the Rat Reproductive Cycle Regulates Spinal Endomorphin 2 Antinociception: Relevance of Endogenous-Biased Agonism. EM2, KOR, MOR
30  2017 Preclinical anaylses of [18F]cEFQ as a PET tracer for imaging metabotropic glutamate receptor type 1 (mGluR1). ---
31  2017 Progressive impairment of cerebellar mGluR signalling and its therapeutic potential for cerebellar ataxia in spinocerebellar ataxia type 1 model mice. mGluR, PF, SCA1
32  2017 [Influence of occupational aluminum exposure on cognitive function and glutamate receptor protein expression in workers]. DSB, DSF, DST, FOM, VFT
33  2016 Activation of mGluR1 contributes to neuronal hyperexcitability in the rat anterior cingulate cortex via inhibition of HCN channels. ACC, CCI, HCN, HCN1, L5 PNs, PKC
34  2016 AMPA Receptor Plasticity in Accumbens Core Contributes to Incubation of Methamphetamine Craving. CP-AMPARs, NAc
35  2016 Cerebellar ataxias: beta-III spectrin's interactions suggest common pathogenic pathways. SCAs, SPARCA1
36  2016 Ionizing Radiation Induces Altered Neuronal Differentiation by mGluR1 through PI3K-STAT3 Signaling in C17.2 Mouse Neural Stem-Like Cells. GABA
37  2016 Molecular evidence of synaptic pathology in the CA1 region in schizophrenia. CA, PSD
38  2016 Novel Scaffold Identification of mGlu1 Receptor Negative Allosteric Modulators Using a Hierarchical Virtual Screening Approach. ---
39  2016 Screening for MOG-IgG and 27 other anti-glial and anti-neuronal autoantibodies in 'pattern II multiple sclerosis' and brain biopsy findings in a MOG-IgG-positive case. AGNA, AMPAR, AQP4, ARHGAP26, CASPR2, CRMP5, DNER, GAD, GluRdelta2, IgG1, ITPR1, LGI1, MOG, MS, NMDAR, PCA2
40  2016 The Metabotropic Glutamate Receptor Subtype 1 Mediates Experience-Dependent Maintenance of Mature Synaptic Connectivity in the Visual Thalamus. dLGN, mGluR1-KO, WT
41  2016 The PET Radioligand 18F-FIMX Images and Quantifies Metabotropic Glutamate Receptor 1 in Proportion to the Regional Density of Its Gene Transcript in Human Brain. ---
42  2016 The thalamic mGluR1-PLCbeta4 pathway is critical in sleep architecture. EEG, NREM
43  2015 Decreased metabotropic glutamate receptor type 1 availability in a patient with spinocerebellar ataxia type 6: A (11)C-ITMM PET study. BPND, PET, SCA6
44  2015 Discovery and biological evaluation of tetrahydrothieno[2,3-c]pyridine derivatives as selective metabotropic glutamate receptor 1 antagonists for the potential treatment of neuropathic pain. ---
45  2015 Epsilon toxin from Clostridium perfringens acts on oligodendrocytes without forming pores, and causes demyelination. ET, NMDAR
46  2015 Facial stimulation induces long-term depression at cerebellar molecular layer interneuron-Purkinje cell synapses in vivo in mice. CB1, eCB, LTD, MF-GC, NMDA, PF-MLI, PF-PC
47  2015 Improved Visualization and Specific Binding for Metabotropic Glutamate Receptor Subtype 1 (mGluR1) Using [11C]ITMM with Ultra-High Specific Activity in Small-Animal PET. CNS, PET, SA
48  2015 Knockdown of STIM1 improves neuronal survival after traumatic neuronal injury through regulating mGluR1-dependent Ca(2+) signaling in mouse cortical neurons. STIM, TBI, TNI
49  2015 Neuregulin 1 signalling modulates mGluR1 function in mesencephalic dopaminergic neurons. NRG1, PI3K-Akt-mTOR
50  2015 Propofol effects on cerebellar long-term depression. PC, PF
51  2015 Synthesis and biological evaluation of aryl isoxazole derivatives as metabotropic glutamate receptor 1 antagonists: a potential treatment for neuropathic pain. ---
52  2015 Synthesis of novel dihydropyridothienopyrimidin-4,9-dione derivatives. ---
53  2015 The Role of a Novel TRMT1 Gene Mutation and Rare GRM1 Gene Defect in Intellectual Disability in Two Azeri Families. ARID, ID
54  2015 [carbonyl-11C]4-Fluoro-N-methyl-N-(4-(6-(methylamino)pyrimidin-4-yl)thiazol-2-yl)benzamide ([11C]FIMX) is an effective radioligand for PET imaging of metabotropic glutamate receptor 1 (mGluR1) in monkey brain. ---
55  2014 Aromatase and estrogen receptor beta expression in the rat olfactory bulb: Neuroestrogen action in the first relay station of the olfactory pathway? ARO, CB, CR, ERbeta, GAD67, TH
56  2014 Effect of catgut implantation at acupoints on GABA(B) and mGluR1 expressions in brain stem of rats with spasticity after stroke. . MAS
57  2014 Glutamate secretion and metabotropic glutamate receptor 1 expression during Kaposi's sarcoma-associated herpesvirus infection promotes cell proliferation. KS, KSHV, LANA-1, PEL, REST/NRSF
58  2014 In vivo imaging of the metabotropic glutamate receptor 1 (mGluR1) with positron emission tomography: recent advance and perspective. PET
59  2014 L-Glutamate supplementation improves small intestinal architecture and enhances the expressions of jejunal mucosa amino acid receptors and transporters in weaning piglets. GOT, GS, mGluR4, ZO-1
60  2014 Metabotropic glutamate receptor 1 mediates melanocyte transformation via transactivation of insulin-like growth factor 1 receptor. IGF-1R
61  2014 Metabotropic glutamate receptor 1 recycles to the cell surface in protein phosphatase 2A-dependent manner in non-neuronal and neuronal cell lines. ---
62  2014 Metabotropic glutamate receptor 1 splice variants mGluR1a and mGluR1b combine in mGluR1a/b dimers invivo. ---
63  2014 mGluR1 within the nucleus accumbens regulates alcohol intake inmice under limited-access conditions. DID, KO, NAc, PLC
64  2014 Molecular recognition of metabotropic glutamate receptor type 1 (mGluR1): synergistic understanding with free energy perturbation and linear response modeling. CNS, FEP, LRMs, mGluRs
65  2014 Mutant ataxin-3 with an abnormally expanded polyglutamine chain disrupts dendritic development and metabotropic glutamate receptor signaling in mouse cerebellar Purkinje cells. PCs, RORalpha, SCA3
66  2014 Noninvasive quantification of metabotropic glutamate receptor type 1 with [C]ITDM: a small-animal PET study. BPND, CNS, Logan Ref, PET
67  2014 PET brain kinetics studies of (11)C-ITMM and (11)C-ITDM,radioprobes for metabotropic glutamate receptor type 1, in a nonhuman primate. ---
68  2014 Prenatal cocaine exposure uncouples mGluR1 from Homer1 and Gq Proteins. FCX, PKC
69  2014 STIM1 controls neuronal Ca⁺ signaling, mGluR1-dependent synaptic transmission, and cerebellar motor behavior. STIM1
70  2014 Synthesis and biological evaluation of 2-substituted quinoline 6-carboxamides as potential mGluR1 antagonists for the treatment of neuropathic pain. SNL
71  2013 11C-LY2428703, a positron emission tomographic radioligand for the metabotropic glutamate receptor 1, is unsuitable for imaging in monkey and human brains. BCRP, P-gp
72  2013 Cerebellar degeneration associated with mGluR1 autoantibodies as a paraneoplastic manifestation of prostate adenocarcinoma. CSF
73  2013 Effects of exposure to low-level lead on spatial learning and memory and the expression of mGluR1, NMDA receptor in different developmental stages of rats. NMDA, NMDAR2
74  2013 Initial human PET studies of metabotropic glutamate receptor type 1 ligand 11C-ITMM. ---
75  2013 Noradrenaline is a stress-associated metaplastic signal at GABA synapses. ---
76  2013 Phosphorylation and feedback regulation of metabotropic glutamate receptor 1 by calcium/calmodulin-dependent protein kinase II. CaMKIIalpha, CT
77  2013 Preclinical and the first clinical studies on [11C]ITMM for mapping metabotropic glutamate receptor subtype 1 by positron emission tomography. PET
78  2013 Synthesis and evaluation in monkey of [(18)F]4-fluoro-N-methyl-N-(4-(6-(methylamino)pyrimidin-4-yl)thiazol-2-yl)benzamide ([(18)F]FIMX): a promising radioligand for PET imaging of brain metabotropic glutamate receptor 1 (mGluR1). ---
79  2013 TRPC3 channel underlies cerebellar long-term depression. CFs, LTD, PFs, TRPC
80  2013 [Hippocampus quinolinic acid modulates glutamate and NMDAR/mGluR1 in chronic unpredictable mild stress-induced depression]. CUMS, ELISA, Glu, NMDA, QUIN
81  2012 Calcium-permeable AMPA receptors in the VTA and nucleus accumbens after cocaine exposure: when, how, and why? CI-AMPARs, CP-AMPARs, MSNs, NAc, VTA
82  2012 Characterization of 1-(2-[18F] fluoro-3-pyridyl)-4-(2-isopropyl-1-oxo- isoindoline-5-yl)-5-methyl-1H-1,2,3-triazole, a PET ligand for imaging the metabotropic glutamate receptor type 1 in rat and monkey brains. PET
83  2012 Deleterious GRM1 mutations in schizophrenia. nsSNPs
84  2012 Glutamate receptor delta2 associates with metabotropic glutamate receptor 1 (mGluR1), protein kinase Cgamma, and canonical transient receptor potential 3 and regulates mGluR1-mediated synaptic transmission in cerebellar Purkinje neurons. PKCgamma, TRPC3
85  2012 Imaging for metabotropic glutamate receptor subtype 1 in rat and monkey brains using PET with [18F]FITM. PET
86  2012 In vivo measurement of the affinity and density of metabotropic glutamate receptor subtype 1 in rat brain using 18F-FITM in small-animal PET. max
87  2012 Metabotropic glutamate receptor 1 (mGluR1): antibody specificity and receptor expression in cultured primary neurons. ---
88  2012 mGluR1 interacts with cystic fibrosis transmembrane conductance regulator and modulates the secretion of IL-10 in cystic fibrosis peripheral lymphocytes. AMPAR, CAL, CF, CFTR, NHERF1, NMDAR
89  2012 Purkinje cell dysfunction and delayed death in plasma membrane calcium ATPase 2-heterozygous mice. AMPAR, cGMP, nNOS, NO, PC, PMCA2, sGC
90  2012 Sequential inter- and intrasubunit rearrangements during activation of dimeric metabotropic glutamate receptor 1. FRET, G protein
91  2012 Subregion-specific role of glutamate receptors in the nucleus accumbens on drug context-induced reinstatement of cocaine-seeking behavior in rats. AMPA, NAc
92  2012 Synthesis and evaluation of novel radioligands for positron emission tomography imaging of metabotropic glutamate receptor subtype 1 (mGluR1) in rodent brain. ---
93  2012 Thalamic model of awake alpha oscillations and implications for stimulus processing. EPSPs, HTC cells, mAChR, RE, TC
94  2012 The analysis of purkinje cell dendritic morphology in organotypic slice cultures. PKC
95  2012 Transient receptor potential canonical channels regulate the induction of cerebellar long-term depression. LTD, TRPC
96  2012 TRPC-Mediated Current Is Not Involved in Endocannabinoid-Induced Short-Term Depression in Cerebellum. PC, PF, TRPC
97  2011 Additive effect of tetramethylpyrazine and deferoxamine in the treatment of spinal cord injury caused by aortic cross-clamping in rats. ---
98  2011 Characterization of the selective mGluR1 antagonist, JNJ16259685, in rodent models of movement and coordination. ---
99  2011 GFP-based evaluation system of recombinant expression through the secretory pathway in insect cells and its application to the extracellular domains of class C GPCRs. GPCRs
100  2011 Long-term potentiation of synaptic response and intrinsic excitability in neurons of the rat medial vestibular nuclei. AHP, EPSP, HFS, IE, ISS, LTP, MVN, NMDARs, Rin