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Abbreviation : mTORC
Long Form : mTOR complex
No. Year Title Co-occurring Abbreviation
2021 mTOR Signaling as a Regulator of Hematopoietic Stem Cell Fate. HSCs, mTOR
2021 mTOR Signaling: The Interface Linking Cellular Metabolism and Hepatitis B Virus Replication. HBV, mTOR
2021 mTOR-mediated calcium transients affect cardiac function in ex vivo ischemia-reperfusion injury. CKO, EC, I/R, mPTP, mTOR, SR
2020 Ascofuranone suppresses invasion and F-actin cytoskeleton organization in cancer cells by inhibiting the mTOR complex 1 signaling pathway. FAK
2020 Characterization of mTOR Activity and Metabolic Profile in Pediatric Rhabdomyosarcoma. RMS
2020 Deubiquitinase OTUD5 is a positive regulator of mTORC1 and mTORC2 signaling pathways. beta-TrCP1, DEPTOR, DUB, mTOR, OTUD5
2020 Hyperphosphorylation of fetal liver IGFBP-1 precedes slowing of fetal growth in nutrient-restricted baboons and may be a mechanism underlying IUGR. AAR, CK, GD, IGF, IUGR, MNR, mTOR, PRM-MS
2020 mTOR sustains inflammatory response in celiac disease. ACD, CD, mTOR, PT
2020 mTORC1 and mTORC2 expression in inner retinal neurons and glial cells. mTOR, mTORC1, RGCs, S6K1
10  2020 P2 7 Receptor Inhibits Astroglial Autophagy via Regulating FAK- and PHLPP1/2-Mediated AKT-S473 Phosphorylation Following Kainic Acid-Induced Seizures. FAK, HSP25, KA, KO, mTOR, P2X7R, PHLPP
11  2020 Regulation of RLR-Mediated Antiviral Responses of Human Dendritic Cells by mTOR. DCs, IFNs, moDCs, mTOR, pDCs, TBK1
12  2020 The GATOR2-mTORC2 axis mediates Sestrin2-induced AKT Ser/Thr kinase activation. AKT, WDR24
13  2019 Enhanced mTOR complex 1 signaling attenuates diabetic cardiac injury in OVE26 mice. mTOR
14  2019 Sin1-mediated mTOR signaling in cell growth, metabolism and immune response. MAPK, mTOR
15  2018 HLA Class II-Triggered Signaling Cascades Cause Endothelial Cell Proliferation and Migration: Relevance to Antibody-Mediated Transplant Rejection. AMR, EC, HLA-II, mTOR
16  2018 mTORC1 and mTORC2 Expression Levels in Oral Squamous Cell Carcinoma: An Immunohistochemical and Clinicopathological Study. mTOR, OSCC
17  2018 Repurposing of mTOR Complex Inhibitors Attenuates MCL-1 and Sensitizes to PARP Inhibition. GBM, HR, SCLC
18  2018 Uropathogenic Escherichia coli invades bladder epithelial cells by activating kinase networks in host cells. BECs, EGFR, PI3K, UPEC, UTIs
19  2017 Mechanistic Target of Rapamycin Is a Novel Molecular Mechanism Linking Folate Availability and Cell Function. mTOR, PCFT, PHT
20  2016 A Novel mTORC1-Dependent, Akt-Independent Pathway Differentiates the Gut Tropism of Regulatory and Conventional CD4 T Cells. ATRA, mTOR, RAR
21  2016 New perspectives on mTOR inhibitors (rapamycin, rapalogs and TORKinibs) in transplantation. mTOR
22  2015 Blockade of the acute activation of mTOR complex 1 decreases hypertrophy development in rats with severe aortic valve regurgitation. AR, LV, mTOR, VO
23  2015 Conditional disruption of rictor demonstrates a direct requirement for mTORC2 in skin tumor development and continued growth of established tumors. mTOR, TPA
24  2015 Hypoxia Increases IGFBP-1 Phosphorylation Mediated by mTOR Inhibition. FGR, IGF-I, IGFBP-1, mTOR, siRNA
25  2015 mTOR Complex Signaling through the SEMA4A-Plexin B2 Axis Is Required for Optimal Activation and Differentiation of CD8+ T Cells. mTOR
26  2015 mTORC2 Deficiency in Myeloid Dendritic Cells Enhances Their Allogeneic Th1 and Th17 Stimulatory Ability after TLR4 Ligation In Vitro and In Vivo. DC, mTOR
27  2015 Protection of pancreatic beta-cells against glucotoxicity by short-term treatment with GLP-1. GLP-1, PI3K
28  2014 Adenosine triphosphate-competitive mTOR inhibitors: a new class of immunosuppressive agents that inhibit allograft rejection. ATP, mTOR, RAPA
29  2014 Ampelopsin suppresses breast carcinogenesis by inhibiting the mTOR signalling pathway. AMP, MNU, mTOR
30  2013 Adaptation to mTOR kinase inhibitors by amplification of eIF4E to maintain cap-dependent translation. IRES, mTOR
31  2013 Combined inhibition of mTORC1 and mTORC2 signaling pathways is a promising therapeutic option in inhibiting pheochromocytoma tumor growth: in vitro and in vivo studies in female athymic nude mice. mTOR
32  2013 Concurrent inhibition of PI3K and mTORC1/mTORC2 overcomes resistance to rapamycin induced apoptosis by down-regulation of Mcl-1 in mantle cell lymphoma. MCL, mTOR, NHL, PI3K
33  2013 Effects of level of nutrient intake and age on mammalian target of rapamycin, insulin, and insulin-like growth factor-1 gene network expression in skeletal muscle of young Holstein calves. CON, ENH, IGF-1, mTOR
34  2013 Equivalent benefit of rapamycin and a potent mTOR ATP-competitive inhibitor, MLN0128 (INK128), in a mouse model of tuberous sclerosis. TSC
35  2013 Metformin inhibits skin tumor promotion in overweight and obese mice. AMPK, TPA
36  2013 Murine dendritic cell rapamycin-resistant and rictor-independent mTOR controls IL-10, B7-H1, and regulatory T-cell induction. B7-H1, DCs, IL, mTOR, RAPA
37  2013 TBCK influences cell proliferation, cell size and mTOR signaling pathway. mTOR
38  2013 The dual mTORC1 and mTORC2 inhibitor AZD8055 inhibits head and neck squamous cell carcinoma cell growth in vivo and in vitro. HNSCC, JNK, mTOR, RNAi
39  2012 Pentoxifylline and propentofylline prevent proliferation and activation of the mammalian target of rapamycin and mitogen activated protein kinase in cultured spinal astrocytes. cAMP, mTOR, S6K, TNF
40  2011 Cardiac raptor ablation impairs adaptive hypertrophy, alters metabolic gene expression, and causes heart failure in mice. mTOR
41  2010 A versatile role of mammalian target of rapamycin in human dendritic cell function and differentiation. DC, mDCs, moDCs, mTOR
42  2010 Fisetin induces autophagic cell death through suppression of mTOR signaling pathway in prostate cancer cells. mTOR