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Abbreviation : p-JNK
Long Form : phosphorylated JNK
No. Year Title Co-occurring Abbreviation
2020 c-Jun NH2 -Terminal Protein Kinase Phosphorylates the Nrf2-ECH Homology 6 Domain of Nuclear Factor Erythroid 2-Related Factor 2 and Downregulates Cytoprotective Genes in Acetaminophen-Induced Liver Injury in Mice. AILI, ARE, Neh, Nrf2
2020 miR-128 regulated the proliferation and autophagy in porcine adipose-derived stem cells through targeting the JNK signaling pathway. ASCs, Bax, Bcl-2, FCM, JNK, miR-128, RT-PCR
2020 Selective hyperactivation of JNK2 in an animal model of temporal lobe epilepsy. JNKs, MAPK
2020 Xiaoyaosan Produces Antidepressant Effects in Rats via the JNK Signaling Pathway. CIS, JNK, p-c-Jun, XYS
2020 [Electroacupuncture improved learning-memory ability by reducing hippocampal apoptosis and suppressing JNK signaling in rats with vascular dementia]. Caspase-8, EA, JNK, TUNEL, VD
2019 Acetyl-11-keto-beta-boswellic acid regulates the repair of rat sciatic nerve injury by promoting the proliferation of Schwann cells. AKBA, ERK, JNK, NF200, pERK
2019 Acute exposure to glycated proteins reduces cardiomyocyte contractile capacity. HMW-AGEs, JNK
2019 Astragalus Polysaccharide Eases G1 Phase-Correlative Bystander Effects through Mediation of TGF- beta R/MAPK/ROS Signal Pathway After Carbon Ion Irradiation in BMSCs. APS, BMSCs, COX-2, MAPK, MN, p-P38, pERK, RIBE, ROS, TGFbetaRII
2019 Case series of dabrafenib-trametinib-induced pyrexia successfully treated with colchicine. AE, DT, FMF, MAPKs
10  2019 Double immunofluorescent evidence that oxidative stress-associated activation of JNK/AP-1 signaling participates in neuropeptide-mediated appetite control. AMPH, AP-1, CART, GP, GST, JNK, NPY, ROS, SOD
11  2019 Liraglutide promotes apoptosis of HepG2 cells by activating JNK signaling pathway. CCK-8, JNK
12  2019 Mitochondrial methionine sulfoxide reductase B2 links oxidative stress to Alzheimer's disease-like pathology. AD, BACE1, MSRB2, p-ERK
13  2019 ROS-mediated JNK pathway critically contributes to PFOS-triggered apoptosis in SH-SY5Y cells. JNK, NAC, PFOS, ROS
14  2019 [Effects of dihydromyricetin on the migration and invasion of human gastric cancer MKN45 cells and its mechanism]. DHM, EMT, JNK, MMP-2, TCM
15  2018 Administration of CoCl2 Improves Functional Recovery in a Rat Model of Sciatic Nerve Transection Injury. BDNF, DLK, GDNF, HIF-1alpha, JNK, NGF
16  2018 Antiapoptotic role of the cellular repressor of E1A-stimulated genes (CREG) in retinal photoreceptor cells in a rat model of light-induced retinal injury. p-AKT, p-P38, pERK
17  2018 APP upregulation contributes to retinal ganglion cell degeneration via JNK3. AICD, APP, ONA, RGC
18  2018 Ethyl Acetate Fraction from Persimmon (Diospyros kaki) Ameliorates Cerebral Neuronal Loss and Cognitive Deficit via the JNK/Akt Pathway in TMT-Induced Mice. ACh, AChE, ATP, Bax, ICR, IRS-1pSer, JNK, MDA, MMP, p-Akt, p-NF-kappaB, p-tau, ROS, SOD, TMT, TNF-alpha
19  2018 Preventive effects of total saponins of Panax japonicus on fatty liver fibrosis in mice. alpha-SMA, CHOP, coll, ERS, HF, JNK, NAFLD, RT-PCR, SPJ, TIMP
20  2018 Protective role and mechanism of snakegourd peel against myocardial infarction in rats. LDH, LVEDP, LVSP, MI, SP, TTC
21  2018 Similar Aquaporin9 and MAPK Expression Profiles in the Liver of Types 1 and 2 Diabetes Mellitus. AQP9, DM, MAPK, p-p38
22  2018 Synergetic and Antagonistic Molecular Effects Mediated by the Feedback Loop of p53 and JNK between Saikosaponin D and SP600125 on Lung Cancer A549 Cells. IPA, SSd
23  2017 c-Jun N-terminal kinase in pancreatic tumor stroma augments tumor development in mice. JNK, mPC, PDAC, SMA, TAF
24  2017 DLK silencing attenuated neuron apoptosis through JIP3/MA2K7/JNK pathway in early brain injury after SAH in rats. CC3, dUTP, EBI, JIP3, SAH, siRNA
25  2017 Xiao Yao San Improves the Anxiety-Like Behaviors of Rats Induced by Chronic Immobilization Stress: The Involvement of the JNK Signaling Pathway in the Hippocampus. CIS, Cyt C, DMSO, EPM, JNK, NSF, p-c-Jun, p.o, XYS
26  2017 [Effects of MAPKs inhibitors on GSH metabolic enzymes in rat hepatocytes]. JNK, MAPKs
27  2017 [The Role of Long Chain Non-coding RNA-Paupar in the Process of Bupivacaine Induced Neurotoxicity]. DRG
28  2016 Anti-amnesic effect of Dendropanax morbifera via JNK signaling pathway on cognitive dysfunction in high-fat diet-induced diabetic mice. ACh, AChE, EFDM, HFD, IPGTT, JNK, MDA, p-Akt, p-IRS, p-tau, SOD
29  2016 c-Jun N-terminal kinase mediates mouse liver injury through a novel Sab (SH3BP5)-dependent pathway leading to inactivation of intramitochondrial Src. DOK4, JNK
30  2016 Cordycepin promotes apoptosis by modulating the ERK-JNK signaling pathway via DUSP5 in renal cancer cells. DKK1, ERK
31  2016 Docosahexaenoic acid confers analgesic effects after median nerve injury via inhibition of c-Jun N-terminal kinase activation in microglia. CCI, CN, DHA, JNK
32  2016 Explore the variation of MMP3, JNK, p38 MAPKs, and autophagy at the early stage of osteoarthritis. LC3, MAPK, MMP3, p-p38
33  2016 Extracellular translationally controlled tumor protein promotes colorectal cancer invasion and metastasis through Cdc42/JNK/ MMP9 signaling. CRC, HRF, rhTCTP, TCTP
34  2016 Soluble DPP-4 up-regulates toll-like receptors and augments inflammatory reactions, which are ameliorated by vildagliptin or mannose-6-phosphate. DPP-4, iNOS, LPS, M6P, sDPP-4, TLR4
35  2016 The protective effect of lycopene on hypoxia/reoxygenation-induced endoplasmic reticulum stress in H9C2 cardiomyocytes. 4-PBA, CHOP, ERS, GRP78, I/R, JNK, LDH, TG
36  2016 [Effect of Acupuncture Intervention on c-jun N-terminal Kinase Signaling in the Hippocampus in Rats with Forced Swimming Stress]. JNK
37  2016 [Effects of extracellular regulated protein kinases protein and impairment of blood testis barriar stucturein of mice with exposure to decabromodiphenyl ether]. BTB, JNK, MAPK, p-p38
38  2015 Deferoxamine reduces intracerebral hemorrhage-induced white matter damage in aged rats. ICH, JNK
39  2015 Hepatocyte X-box binding protein 1 deficiency increases liver injury in mice fed a high-fat/sugar diet. HFS, NASH, PA, UPR, XBP-1s
40  2015 [Role and mechanism of heat shock protein 70 in airway hypersecretion]. CSE, ELISA, HSP70, JNK, PCR
41  2015 [Transforming growth factor-beta1 induced cellular proliferation and collagen synthesis was mediated by reactive oxygen species in pulmonary fibroblasts]. NAC, ROS
42  2014 Atorvastatin ameliorates myocardial ischemia/reperfusion injury through attenuation of endoplasmic reticulum stress-induced apoptosis. CHOP, ERS, I/R, LAD, TTC, TUNEL
43  2014 Colistin-induced nephrotoxicity in mice involves the mitochondrial, death receptor, and endoplasmic reticulum pathways. CDK2, Cyt C, FADD, SOD
44  2014 Dahuang Fuzi Decoction ameliorates tubular epithelial apoptosis and renal damage via inhibiting TGF-beta1-JNK signaling pathway activation in vivo. AP, CKD, DFD, JNK, NAG, TGF, TUNEL
45  2014 Novel role of silent information regulator 1 in acute endothelial cell oxidative stress injury. HUVEC, OSI, ROS, SIRT1
46  2014 Polyphyllin D induces apoptosis in U87 human glioma cells through the c-Jun NH2-terminal kinase pathway. Bax, Bcl-2, PD, t-JNK
47  2014 Role of platelet-derived growth factor-BB (PDGF-BB) in human pulmonary artery smooth muscle cell proliferation. hPASMCs, PAH, PASMCs, PCNA, PDGF, PDGF-BB, SD
48  2014 Sinodielide A exerts thermosensitizing effects and induces apoptosis and G2/M cell cycle arrest in DU145 human prostate cancer cells via the Ras/Raf/MAPK and PI3K/Akt signaling pathways. ERK, JNK, MAPK, p-Akt, PI3K, SA
49  2014 [Roles of ceruloplasmin in silica-induced JNK/ERK/AP-1 cell signaling pathway change]. Cp, HELFs
50  2014 [Total flavonoids from Astragalus complanatus attenuates lung injury following paraquat poisoning in rats through inhibiting excessive endoplasmic reticulum stress and c-Jun N-terminal kinase pathway]. DMSO, ERS, FAC, GRP78, IQA, JNK, PQ, RT-PCR, SD, TLW
51  2013 Activation of PRMT1 and PRMT5 mediates hypoxia- and ischemia-induced apoptosis in human lung epithelial cells and the lung of miniature pigs: the role of p38 and JNK mitogen-activated protein kinases. ERK, HIF, MAPK, p-p38, PRMTs, siRNA
52  2013 Activations of GABAergic signaling, HSP70 and MAPK cascades are involved in baicalin's neuroprotection against gerbil global ischemia/reperfusion injury. HSP70, MAPKs, p-p38, pERK
53  2013 Baicalin attenuates acute myocardial infarction of rats via mediating the mitogen-activated protein kinase pathway. CK, cTnT, ERK, JNK, LDH, MAPKs, p-p38, pERK
54  2013 Opposite effects of JNK and p38 MAPK signaling pathways on furazolidone-stimulated S phase cell cycle arrest of human hepatoblastoma cell line. FZD, JNK, p-p38, p38 MAPK
55  2012 Calcium entry mediates hyperglycemia-induced apoptosis through Ca(2+)/calmodulin-dependent kinase II in retinal capillary endothelial cells. 2-APB, ATP, CaMKII, HG, JNK, NG, p-CaMKII, RECs
56  2012 Chronic mechanical stress induces mucin 5AC expression in human bronchial epithelial cells through ERK dependent pathways. ELISA, MUC5AC, NHBE, p-FAK-Y397, p-P38, RT-PCR, siRNA
57  2012 [Effects of electroacupuncture at neiguan (PC6) on c-Jun NH2-teminal kinase signaling pathways in hypertrophic myocardial cells]. Ang II, CH, EA, HWI, ISO, JNK, LVWI
58  2012 [Effects of Panax notoginseng saponins on pneumocyte apoptosis and c-Jun N-terminal kinase in lung ischemia/reperfusion injury]. AI, I/R, IAR, JNK, PNS, TUNEL
59  2012 [Protective effects and mechanism of SP600125 on lung ischemia/reperfusion injury in rats]. AI, IAR, JNK, TUNEL
60  2011 Enhanced apoptotic and reduced protective response in chondrocytes following endoplasmic reticulum stress in osteoarthritic cartilage. CCasp3, ER, OA, p-PERK, Ub, XBP1
61  2011 Inhibition of spinal astrocytic c-Jun N-terminal kinase (JNK) activation correlates with the analgesic effects of ketamine in neuropathic pain. JNK, LPS, MAPK, SNL
62  2011 Interference of the apoptotic signaling pathway in RGC stress response by SP600125 in moderate ocular hypertensive rats. IOP, RGCs
63  2011 Neuroprotective signaling pathways are modulated by adenosine in the anoxia tolerant turtle. A1R, CCPA, DPCPX, MAPK
64  2011 Ox-LDL-induced LOX-1 expression in vascular smooth muscle cells: role of reactive oxygen species. LOX-1, oxLDL, ROS, VSMCs
65  2010 Different apoptotic reactions of dorsal root ganglion A- and B-cells after sciatic nerve axotomy: effect of p75 neurotrophin receptor. DRG, ERK, JNK, P-c-jun, p-p38, pERK
66  2010 [Effect of electroacupuncture on hippocampal apoptosis and JNK signal pathway in chronic stress depression rats]. EA, FITC, JNK, PI
67  2009 Inhibition of RNA-dependent protein kinase (PKR) leads to cancer cell death and increases chemosensitivity. ds, p-cJun, PKR
68  2009 Neuropeptide substance P attenuates hyperoxia-induced oxidative stress injury in type II alveolar epithelial cells via suppressing the activation of JNK pathway. AECIIs, c-JNK, FACS, SP, TEM
69  2007 Effect of JNK inhibition on cisplatin-induced renal damage. JNK
70  2007 Immunohistochemical detection of phosphorylated JNK, p38 MAPK, and ERK5 in ameloblastic tumors. MAPKs
71  2007 Stem cell marker nestin and c-Jun NH2-terminal kinases in tumor and peritumor areas of glioblastoma multiforme: possible prognostic implications. GBM, tJNK
72  2006 Decreased expression of phosphorylated JNK in breast infiltrating ductal carcinoma is associated with a better overall survival. IDC, JNK
73  2005 Contribution of mitogen-activated protein kinases to NMDA-induced neurotoxicity in the rat retina. ERK, INL, JNK, MAPKs, NMDA, p-MAPKs, p-p38, pERK, RGCL, TUNEL
74  2005 Protein kinase p-JNK is correlated with the activation of AP-1 and its associated Jun family proteins in hepatocellular carcinoma. HBV, HCC, JNK
75  2001 Differential activation of MAPK during Mullerian duct growth and apoptosis: JNK and p38 stimulation by DES blocks tissue death. JNK, MAPKs, MD
76  2000 Developmental changes in the localization of activated C-JUN N-terminal kinase (JNK/SAPK) in the chick spinal cord. Cdk5