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[Related PubMed/MEDLINE]
Total Number of Papers: 197
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| Abbreviation |
: p-JNK |
| Long Form |
: phosphorylated c-Jun N-terminal kinase |
|
| No. |
Year |
Title |
Co-occurring Abbreviation |
| 1 |
2020 |
(-)-Epigallocatechin-3-gallate induces interferon-lamda2 expression to anti-influenza A virus in human bronchial epithelial cells (BEAS-2B) through p38 MAPK signaling pathway. |
EGCG, IAV, IFN, NP, p-ERK, pp38 MAPK, qRT-PCR |
| 2 |
2020 |
7-methoxyflavanone alleviates neuroinflammation in lipopolysaccharide-stimulated microglial cells by inhibiting TLR4/MyD88/MAPK signalling and activating the Nrf2/NQO-1 pathway. |
7MF, COX-2, Iba-1, ICAM-1, IL-6, iNOS, LPS, MCP-1, MyD88, NQO1, Nrf2, TLR4, TNF-alpha |
| 3 |
2020 |
Anti-Amnesic Effect of Walnut via the Regulation of BBB Function and Neuro-Inflammation in Abeta1-42-Induced Mice. |
ACh, AChE, BBB, ChAT, COX-2, HO-1, ICR, IL-1beta, MDA, MMP, p-Akt, ROS, SOD, TNF-alpha, TNFR1, ZO-1 |
| 4 |
2020 |
Chebulanin exerts its anti-inflammatory and anti-arthritic effects via inhibiting NF-kappaB and MAPK activation in collagen-induced arthritis mice. |
CIA, ERK, IL-6, LPS, MAPK, NF-kappaB, p-IkappaBalpha, RA, TNF-alpha |
| 5 |
2020 |
Dendrobium officinale Attenuates Myocardial Fibrosis via Inhibiting EMT Signaling Pathway in HFD/STZ-Induced Diabetic Mice. |
DCM, DOE, EMT, HDL-C, HFD, LDL-C, p-IRS-1, PPAR-alpha, STZ, TC, TG, TGF-beta1 |
| 6 |
2020 |
Effect of Hataedock Treatment on Epidermal Structure Maintenance through Intervention in the Endocannabinoid System. |
AD, CB, CD1a, DFE, ECS, GPR55, GPX4, HTD, LASS2, p-ERK, p-mTOR, PEA |
| 7 |
2020 |
Effect of Wenshen-Yanggan Decoction on Movement Disorder and Substantia Nigra Dopaminergic Neurons in Mice with Chronic Parkinson's Disease. |
Bcl-2, DA, ELISA, PD, TH |
| 8 |
2020 |
Efficacy of decoction from Jieduan Niwan formula on rat model of acute-on-chronic liver failure induced by porcine serum. |
ACLF, AI, AST, BUN, Cr, Cyt C, HMGB-1, IL-10, IL-1beta, IL-6, JDNW, PTA, TBIL, TGF-beta1, TNF-alpha |
| 9 |
2020 |
Glycine, the smallest amino acid, confers neuroprotection against D-galactose-induced neurodegeneration and memory impairment by regulating c-Jun N-terminal kinase in the mouse brain. |
Gly, LPO, ROS, Syn, SYP |
| 10 |
2020 |
Hydroxytyrosol enhances cisplatin-induced ototoxicity: Possible relation to the alteration in the activity of JNK and AIF pathways. |
AIF, CCK-8, DCFH-DA, HEI-OC1, HT, TdT |
| 11 |
2020 |
Laodelphax striatellus Atg8 facilitates Rice stripe virus infection in an autophagy-independent manner. |
Atg8, RSV, VgR |
| 12 |
2020 |
Leptin improves intestinal flora dysfunction in mice with high-fat diet-induced obesity. |
HFD, TLR4 |
| 13 |
2020 |
Li-Dan-He-Ji Improves Infantile Cholestasis Hepatopathy Through Inhibiting Calcium-Sensing Receptor-Mediated Hepatocyte Apoptosis. |
CaSR, ICH, LDHJ, p-ERK |
| 14 |
2020 |
Long-term effects of the glucocorticoid receptor modulator CORT113176 in murine motoneuron degeneration. |
ALS, GR, HMGB1, IL18, MyD88, NF-kappaB, TNF |
| 15 |
2020 |
Methylation-Induced Silencing of ALDH2 Facilitates Lung Adenocarcinoma Bone Metastasis by Activating the MAPK Pathway. |
ALDH2, BM, EMT, LUAD, MAPK, MBD4 |
| 16 |
2020 |
MiR-144 affects proliferation and apoptosis of high glucose-induced AC16 cardiomyocytes by regulating CTRP3/JNK signaling. |
CCK-8, CTRP3, DCM, miRNAs, qRT-PCR |
| 17 |
2020 |
NOD2/c-Jun NH2-Terminal Kinase Triggers Mycoplasma ovipneumoniae-Induced Macrophage Autophagy. |
CCU, MDP, RT-PCR, siRNA |
| 18 |
2020 |
Oral Administration of Alpha Linoleic Acid Rescues Abeta-Induced Glia-Mediated Neuroinflammation and Cognitive Dysfunction in C57BL/6N Mice. |
ALA, APP, BACE-1, GFAP, i.c.v, TLR4, TNF |
| 19 |
2020 |
Schisandra Chinensis Acidic Polysaccharide Improves the Insulin Resistance in Type 2 Diabetic Rats by Inhibiting Inflammation. |
CRP, IL-1beta, IL-6, IR, NF-kappaB, p-Akt, p-IRS-1, p-PI3K, SCAP, T2D, TNF-alpha |
| 20 |
2020 |
Tangeretin mitigates l-NAME-induced ventricular dysfunction and remodeling through the AT1R/pERK1/2/pJNK signaling pathway in rats. |
eNOS, l-NAME |
| 21 |
2020 |
[Effect of psoralen on rat osteoblasts injuries induced by TCP wear particles in vitro and its mechanism]. |
TCP |
| 22 |
2019 |
A30P mutant alpha-synuclein impairs autophagic flux by inactivating JNK signaling to enhance ZKSCAN3 activity in midbrain dopaminergic neurons. |
PD |
| 23 |
2019 |
Adipokine Chemerin Stimulates Progression of Atherosclerosis in ApoE-/- Mice. |
IL-1beta, NF-kappaBp65, p-p38 MAPK, PCNA, TGF-beta1, TNF-alpha |
| 24 |
2019 |
Ambroxol attenuates cisplatin-induced hepatotoxicity and nephrotoxicity via inhibition of p-JNK/p-ERK. |
p-ERK |
| 25 |
2019 |
Caffeine May Abrogate LPS-Induced Oxidative Stress and Neuroinflammation by Regulating Nrf2/TLR4 in Adult Mouse Brains. |
Bax, Bcl-2, HO-1, LPO, LPS, Nrf2, p-NF-kB, ROS, TLR4 |
| 26 |
2019 |
Chlorogenic acid protects against aluminum toxicity via MAPK/Akt signaling pathway in murine RAW264.7 macrophages. |
Al, MAPK |
| 27 |
2019 |
Chronic Alcohol Exposure Induced Neuroapoptosis: Diminishing Effect of Ethyl Acetate Fraction from Aralia elata. |
3,5-diCQA, ACh, AChE, Bax, CQA, DCF-DA, MDA, MTT, p-Akt, pTau, SOD |
| 28 |
2019 |
Down-regulation of long non-coding RNA MALAT1 inhibits granulosa cell proliferation in endometriosis by up-regulating P21 via activation of the ERK/MAPK pathway. |
AUC, CDK2, ERK, GCs, lncRNA, MALAT1, MAPK, qRT-PCR, ROC |
| 29 |
2019 |
Effect of transcutaneous electrical acupuncture point stimulation on expression of p-JNK in the dorsal root ganglion in a rat model of myofascial pain syndrome. |
DRG, MPS, PWTL, TEAS |
| 30 |
2019 |
Esculentoside B inhibits inflammatory response through JNK and downstream NF-kappaB signaling pathway in LPS-triggered murine macrophage RAW 264.7 cells. |
EsB, NF-kappaB, NO, TCM |
| 31 |
2019 |
Hesperetin, a Citrus Flavonoid, Attenuates LPS-Induced Neuroinflammation, Apoptosis and Memory Impairments by Modulating TLR4/NF-kappaB Signaling. |
Bcl-2, IL-1beta, LPS, Nrf2, p-NF-kappaB, pCREB, PSD-95, ROS/LPO, TLR4, TNF-alpha |
| 32 |
2019 |
Mangiferin ameliorates acetaminophen-induced hepatotoxicity through APAP-Cys and JNK modulation. |
MAN, NAPQI, ROS |
| 33 |
2019 |
Phytomedicine-Based Potent Antioxidant, Fisetin Protects CNS-Insult LPS-Induced Oxidative Stress-Mediated Neurodegeneration and Memory Impairment. |
CD14, CNS, i.p, IL1-beta, LPS, ROS, TNF-alpha |
| 34 |
2019 |
Protective effect of Cordyceps militaris against hydrogen peroxide-induced oxidative stress in vitro. |
CM, NO, p-ERK, p-p38 MAPK, ROS |
| 35 |
2019 |
Retinoic Receptor Signaling Regulates Hypertrophic Chondrocyte-specific Gene Expression. |
MAPK, MMP13, RT-PCR, TG-2 |
| 36 |
2019 |
The Effect of Schisandra chinensis Baillon on Cross-Talk between Oxidative Stress, Endoplasmic Reticulum Stress, and Mitochondrial Signaling Pathway in Testes of Varicocele-Induced SD Rat. |
CTR, ER, FSH, GPx, Grp 78, LH, MDA, p-IRE1alpha, RNS, ROS, SC, SOD, StAR, VC, VC |
| 37 |
2019 |
The Role of Phospho-c-Jun N-Terminal Kinase Expression on hepatocyte Necrosis and Autophagy in the Cholestatic Liver. |
BDL, TAA |
| 38 |
2019 |
The Superior Antitumor Effect of Self-Assembled Paclitaxel Nanofilaments for Lung Cancer Cells. |
CHOP, ER, IRE1alpha, NSCLC, PERK, PTX, SA |
| 39 |
2019 |
YQWY decoction reverses cardiac hypertrophy induced by TAC through inhibiting GATA4 phosphorylation and MAPKs. |
ANP, EF, ELISA, FS, HE, IF, IHC, MAPKs, MYH7, NT-proBNP, p-ERK, P-GATA4, P-P38, TAC, TTE, WB, YQWY |
| 40 |
2019 |
[Effect of rivaroxaban on the injury during endotoxin-induced damage to human umbilical vein endothelial cells]. |
ELISA, FXa, HUVEC, LPS, MAPK, NF-KappaB, p-NF-KappaBp65, p-TAK1, TNF-alpha |
| 41 |
2019 |
[Salidroside induces anti-tumor effect in dendritic cells via ERK pathway]. |
CTLs, DCs, JNK, MAPK/ERK, NS, pERK, Sal |
| 42 |
2018 |
17beta-Estradiol via SIRT1/Acetyl-p53/NF-kB Signaling Pathway Rescued Postnatal Rat Brain Against Acute Ethanol Intoxication. |
p-mTOR, p-NF-kB, ROS |
| 43 |
2018 |
Anti-fibrotic effects of pirfenidone by interference with the hedgehog signalling pathway in patients with systemic sclerosis-associated interstitial lung disease. |
GLI1, Hh, pGSK-3beta, pSMAD2, SSc-ILD, Sufu |
| 44 |
2018 |
Beneficial Role of Rosuvastatin in Blood-Brain Barrier Damage Following Experimental Ischemic Stroke. |
BBB, LRP1, MAPK, MCAO, MMPs, p-ERK, PDGFRalpha, rt-PA, TIMPs |
| 45 |
2018 |
CDK5RAP1 targeting NF-kappaB signaling pathway in human malignant melanoma A375 cell apoptosis. |
BAD, Bcl-2, Bcl-xl, CDK5RAP1, NF-kappaB, PDTC, ROS, siRNA |
| 46 |
2018 |
Downregulated apoptosis and autophagy after anti-Abeta immunotherapy in Alzheimer's disease. |
aCasp-3, AD, GSK3betatyr216 |
| 47 |
2018 |
Effect of silibinin on CFLAR-JNK pathway in oleic acid-treated HepG2 cells. |
CYP2E1, NASH, NO, NRF2, OA, p-Akt, PI3K, PNPLA3, PPARalpha, SREBP-1C, TG |
| 48 |
2018 |
Ethyl acetate fraction from Hibiscus sabdariffa L. attenuates diabetes-associated cognitive impairment in mice. |
CQA, DM, MWM, p-tau, STZ |
| 49 |
2018 |
Functional components in Scutellaria barbata D. Don with anti-inflammatory activity on RAW 264.7 cells. |
--- |
| 50 |
2018 |
Ginkgo biloba Leaf Extract Protects against Myocardial Injury via Attenuation of Endoplasmic Reticulum Stress in Streptozotocin-Induced Diabetic ApoE-/- Mice. |
CHOP, STZ |
| 51 |
2018 |
Hepatoprotective effect of methyl ferulic acid against carbon tetrachloride-induced acute liver injury in rats. |
AST, Bax, Bcl, IL, MAPK, MFA, NOX, ROS, TAC, TBARS, TNF |
| 52 |
2018 |
Hyperbaric Oxygen Alleviates the Inflammatory Response Induced by LPS Through Inhibition of NF-kappaB/MAPKs-CCL2/CXCL1 Signaling Pathway in Cultured Astrocytes. |
CCL2, HBOT, LPS, p-ERK, p-NF-kappaB, p-p38 |
| 53 |
2018 |
Lutein and Zeaxanthin Isomers Protect against Light-Induced Retinopathy via Decreasing Oxidative and Endoplasmic Reticulum Stress in BALB/cJ Mice. |
ATF4, ERG, ERS, Nrf2, OS, p-PERK |
| 54 |
2018 |
Mechanism of Astragalus polysaccharides in attenuating insulin resistance in Rats with type 2 diabetes mellitus via the regulation of liver microRNA‑203a‑3p. |
APS, CHOP, ERS, GK, GRP, IR, mi, miR, T2DM |
| 55 |
2018 |
Neonatal hyperglycemia induces cell death in the rat brain. |
Bax, Bcl-2, CNS, FJC, GSK3beta, JNK, p-Akt, STZ |
| 56 |
2018 |
Oxymatrine Causes Hepatotoxicity by Promoting the Phosphorylation of JNK and Induction of Endoplasmic Reticulum Stress Mediated by ROS in LO2 Cells. |
ER, NAC, OMT |
| 57 |
2018 |
Peroxiredoxin1 promotes cell proliferation, migration and invasion of colorectal cancer via p38MAPK signaling. |
CCK-8, ERK, JNK, p-ERK, p-p38, PRDX1 |
| 58 |
2018 |
Programmed cell death 4 overexpression enhances sensitivity to cisplatin via the JNK/c-Jun signaling pathway in bladder cancer. |
BCa, EMT, JNK, PDCD4, PDCD4-pcDNA3 |
| 59 |
2018 |
Protective effect of MOTILIPERM in varicocele-induced oxidative injury in rat testis by activating phosphorylated inositol requiring kinase 1alpha (p-IRE1alpha) and phosphorylated c-Jun N-terminal kinase (p-JNK) pathways. |
ER, MDA, p-IRE1alpha, RNS, ROS |
| 60 |
2018 |
RBBP6 promotes human cervical carcinoma malignancy via JNK signaling pathway. |
RBBP6 |
| 61 |
2018 |
Sex Differences in the Effects of a Kappa Opioid Receptor Antagonist in the Forced Swim Test. |
KOR, nor-BNI |
| 62 |
2018 |
Subclinical hypothyroidism in pregnant rats impaired learning and memory of their offspring by promoting the p75NTR signal pathway. |
CON, LTP, MWM, p75NTR, SCH |
| 63 |
2018 |
Transforming growth factor-beta decreases side population cells in hepatocellular carcinoma in vitro. |
CD, HCC, SP, TGF-beta |
| 64 |
2018 |
TSC1 deletion in fibroblasts alleviates lipopolysaccharide-induced acute kidney injury. |
AKI, ECE1, EDN1, JNK, LPS, MEFs, mTORC1, pS6, TSC1 |
| 65 |
2018 |
[Effect and mechanism of dexmedetomidine on lungs in patients of sepsis complicated with acute respiratory distress syndrome]. |
APACHE II, ARDS, BALF, ELISA, ICU, IL-6, MV, MyD88, RASS, TLR4 |
| 66 |
2018 |
[Salidroside inhibits inflammatory factor release in BV-2 cells through p38 and JNK pathways]. |
p-p38 |
| 67 |
2017 |
Carvedilol alleviates the biliary cirrhosis through inhibiting the endoplasmic reticulum stress. |
alpha-SMA, AST, ATF4, COX-2, iNOS, IRE1, MDA, RT-PCR, SOD, TBIL, TGF-beta1 |
| 68 |
2017 |
Daphnoretin modulates differentiation and maturation of human dendritic cells through down-regulation of c-Jun N-terminal kinase. |
DCs |
| 69 |
2017 |
DBA-induced caspase-3-dependent apoptosis occurs through mitochondrial translocation of cyt-c in the rat hippocampus. |
cyt c, DBA, p-ASK1, PARP-1, PKCdelta, ROS, SOD |
| 70 |
2017 |
GADD45a Regulates Olaquindox-Induced DNA Damage and S-Phase Arrest in Human Hepatoma G2 Cells via JNK/p38 Pathways. |
GADD45a, p-ERK, p-p38, ROS |
| 71 |
2017 |
Ginkgetin inhibits growth of breast carcinoma via regulating MAPKs pathway. |
GK, MAPKs, p-ERK |
| 72 |
2017 |
Ginsenoside Rg1 Protects Cardiomyocytes Against Hypoxia/Reoxygenation Injury via Activation of Nrf2/HO-1 Signaling and Inhibition of JNK. |
GSH-Px, HO-1, Nrf2, ROS, SOD |
| 73 |
2017 |
IGFBP2 enhances adipogenic differentiation potentials of mesenchymal stem cells from Wharton's jelly of the umbilical cord via JNK and Akt signaling pathways. |
IGFBP-2, MSC, PDLSCs |
| 74 |
2017 |
Interactions between Sirt1 and MAPKs regulate astrocyte activation induced by brain injury in vitro and in vivo. |
IL-1beta, MAPK, mNSS, p-ERK, p-p38 |
| 75 |
2017 |
Inulin-Type Fructans Modulates Pancreatic-Gut Innate Immune Responses and Gut Barrier Integrity during Experimental Acute Pancreatitis in a Chain Length-Dependent Manner. |
AP, IRAK4, ITFs, NF-kappaB |
| 76 |
2017 |
Involvement of the MEK-ERK/p38-CREB/c-fos signaling pathway in Kir channel inhibition-induced rat retinal Muller cell gliosis. |
COH, GFAP, MAPK, pCREB |
| 77 |
2017 |
miR-214 suppresses the osteogenic differentiation of bone marrow-derived mesenchymal stem cells and these effects are mediated through the inhibition of the JNK and p38 pathways. |
ALP, BMSCs, Col I, FGF, miR, OCN, OPN, p-p38 |
| 78 |
2017 |
Molecular mechanisms of anticancer activity of deoxyelephantopin in cancer cells. |
DOE, p-mTOR, p-STAT3, PARP, uPA, uPAR |
| 79 |
2017 |
Neuroprotective effects of astragaloside IV on Parkinson disease models of mice and primary astrocytes. |
AS-IV, Bax, MPTP, PD |
| 80 |
2017 |
Periostin promotes migration and osteogenic differentiation of human periodontal ligament mesenchymal stem cells via the Jun amino-terminal kinases (JNK) pathway under inflammatory conditions. |
ALP, JNK, MAPK, MSC, PDLSCs, POSTN, rhPOSTN |
| 81 |
2017 |
Role of Paeonol in an Astrocyte Model of Parkinson's Disease. |
Bcl-2, COX-2, DA, FCM, iNOS, p-ERK, PD, SNc |
| 82 |
2017 |
Shenfuqiangxin Capsule inhibits apoptosis through mitogen-activated protein kinase signal pathway in rats with cardio-renal syndrome induced by infrarenal aortic-clamping. |
CRS, HRP, MAPK, p-p38, RT-PCR |
| 83 |
2017 |
The expression and significance of IL-6, IFN-gamma, SM22alpha, and MMP-2 in rat model of aortic dissection. |
AD, BAPN, IFN-gamma, IHC, IL-6, MMP-2, SM22alpha |
| 84 |
2017 |
Urotensin II inhibitor eases neuropathic pain by suppressing the JNK/NF-kappaB pathway. |
CCI, IL-1beta, NF-kappaB, TNF-alpha, UII |
| 85 |
2017 |
Wheat germ agglutinin-conjugated liposomes incorporated with cardiolipin to improve neuronal survival in Alzheimer's disease treatment. |
AD, CL, CRM, LIP, NGF, p-p38 |
| 86 |
2017 |
[Biliverdin protects the isolated lungs from ischemia/reperfusion injury via anti-apoptosis]. |
BV, Cst, HO-1, LIRI, SD, TUNEL, VT |
| 87 |
2017 |
[Effect of heat shock factor 1 on airway hyperresponsiveness and airway inflammation in mice with allergic asthma]. |
BALF, HMGB1, HSF1, IFN-gamma, IL-13, IL-4, IL-5, OVA |
| 88 |
2017 |
[Effect of RNA Interference-silenced TAK1 on Kasumi-1 cell Proliferation Inhibition Induced by As2O3 and Its Mechanism]. |
TAK1 |
| 89 |
2017 |
[Effects of TAK gene silencing on the expressions of IL-6 and IL-8 induced by TNF-alpha in fibroblast-like synoviocytes]. |
NF-kappaB, p-ERK, P-P38, p-p65, RA, ScRNA, TAK1 |
| 90 |
2016 |
Agglutinin isolated from Arisema heterophyllum Blume induces apoptosis and autophagy in A549 cells through inhibiting PI3K/Akt pathway and inducing ER stress. |
AHA, AVOs, CHOP, IRE1alpha, p-eIF2alpha, RA |
| 91 |
2016 |
Anti-inflammatory activity of ethanolic extract from skipjack tuna (Katsuwonus pelamis) heart in LPS-induced RAW 264.7 cells and mouse ear edema model. |
COX-2, IL-6, iNOS, LPS, MAPKs, NF-kappaB p65, NO, p-ERK, TNF-alpha |
| 92 |
2016 |
Anti-tumor activity of the TRPM8 inhibitor BCTC in prostate cancer DU145 cells. |
BCTC, CDK, p-p38, PCa, TRPM8 |
| 93 |
2016 |
Cerebral dopamine neurotrophic factor alleviates Abeta25-35-induced endoplasmic reticulum stress and early synaptotoxicity in rat hippocampal cells. |
AD, CDNF, ER, p-eIF2alpha, PSD-95 |
| 94 |
2016 |
Diterpenoid Tanshinones, the extract from Danshen (Radix Salviae Miltiorrhizae) induced apoptosis in nine human cancer cell lines. |
ATF4, p-eIF2alpha, PARP |
| 95 |
2016 |
Endoplasmic reticulum stress-induced neuronal inflammatory response and apoptosis likely plays a key role in the development of diabetic encephalopathy. |
4-PBA, ATF6, DEP, ER, GRP78, HG, IL-6, TNF-alpha, XBP1 |
| 96 |
2016 |
Fasudil inhibits LPS-induced migration of retinal microglial cells via regulating p38-MAPK signaling pathway. |
LPS, MMP-2, pp38 MAPK, RMG |
| 97 |
2016 |
Glycine inhibits ethanol-induced oxidative stress, neuroinflammation and apoptotic neurodegeneration in postnatal rat brain. |
COX2, FJB, Gly, p-NF-kB, ROS, TNF-alpha |
| 98 |
2016 |
High-Dose Fluoride Impairs the Properties of Human Embryonic Stem Cells via JNK Signaling. |
EB, hESCs, MAPKs, MMP, ROS |
| 99 |
2016 |
IGFBP5 enhances osteogenic differentiation potential of periodontal ligament stem cells and Wharton's jelly umbilical cord stem cells, via the JNK and MEK/Erk signalling pathways. |
ALP, IGFBP-5, MSC, PDLSCs, rhIGFBP5, WJCMSCs |
| 100 |
2016 |
miR-613 suppresses ischemia-reperfusion-induced cardiomyocyte apoptosis by targeting the programmed cell death 10 gene. |
Bcl-2, CHOP, I/R, LDH, MDA, miRNAs, p-Akt, PDCD10 |
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