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Abbreviation : sIL-6R
Long Form : soluble interleukin-6 receptor
No. Year Title Co-occurring Abbreviation
2020 A comparison study of metabolic profiles, immunity, and brain gray matter volumes between patients with bipolar disorder and depressive disorder. BD, BMI, CRP, HDL, sIL-2R, sTNF-R1, UD
2020 Association of pro-inflammatory cytokines with clinical features in euthymic patients with Bipolar-I-Disorder. BD-I, GAF, HC, IL-1beta, PSQI, TNF-alpha, YMRS
2020 Inflammatory biomarkers and risk of ischemic stroke and subtypes: A 2-sample Mendelian randomization study. CRP, IL-1ra, IVW, MEGASTROKE
2020 Partial Normalization of Biomarkers of Inflammation and Immune Activation Among Virally Suppressed Men With HIV Infection and High ART Adherence. ART, CCL2, IFN-gamma, IL-6, MACS, MWH
2020 Serum Levels of Interleukin-8 and Soluble Interleukin-6 Receptor in Patients with Stage-I Multiple Myeloma: A Case-Control Study. ELISA, IL-8, MM
2019 ADAM17: An Emerging Therapeutic Target for Lung Cancer. ADAM17, EGFR, LAC, NSCLC, SCLC, TNF-alpha
2019 Biological variation of immunological blood biomarkers in healthy individuals and quality goals for biomarker tests. CVI, IL-1ra, MIP-1beta, sCD14, sCD40L, sgp130, sIL-2Ralpha, sTNF-RII, TNF-alpha
2019 IL-6 and sIL-6R induces STAT3-dependent differentiation of human VSMCs into osteoblast-like cells through JMJD2B-mediated histone demethylation of RUNX2. ChIP, ChIP-PCR, hVSMCs, IL-6, JMJD, STAT, VSMCs
2019 Inflammation and Risk of Depression in HIV: Prospective Findings From the Multicenter AIDS Cohort Study. EFA, EIPs, HIV, IP-10, sIL-2Ralpha, sTNFR2
10  2019 Interleukin-6 and tumour necrosis factor-alpha cooperatively promote cell cycle regulators and proliferate rheumatoid arthritis fibroblast-like synovial cells. CDK4, IL-6, phospho-pRB, pRb, RA-FLSs, TNF-alpha
11  2019 Leucine-Rich Alpha-2-Glycoprotein 1 in Serum Is a Possible Biomarker to Predict Response to Preoperative Chemoradiotherapy for Esophageal Cancer. AUC, CRP, LRG1, PCRT, ROC
12  2019 One week of magnesium supplementation lowers IL-6, muscle soreness and increases post-exercise blood glucose in response to downhill running. CK, IL-6, TT
13  2019 Soluble interleukin-6 receptor in young adults and its relationship with body composition and autonomic nervous system. IL-6, TNF alpha
14  2019 [Increased serum IL-6 and soluble IL-6 receptor in breast cancer patients after radiotherapy are correlated with proportions of immune cells]. IL-6
15  2018 The association between occupational lead exposure and serum levels of selected soluble receptors. sEGFR, sVEGFR-2
16  2017 Clinical significance of GCF sIL-6R and calprotectin to evaluate the periodontal inflammation. ---
17  2017 Inflammatory Biomarkers and Risk of Schizophrenia: A 2-Sample Mendelian Randomization Study. CRP, IL-1ra
18  2017 Meprin Metalloproteases Generate Biologically Active Soluble Interleukin-6 Receptor to Induce Trans-Signaling. ADAM
19  2017 Persistent, Albeit Reduced, Chronic Inflammation in Persons Starting Antiretroviral Therapy in Acute HIV Infection. ART, CRP, HA, HIV, I-FABP, sCD14, TNF
20  2017 Structural and functional correlates of serum soluble IL-6 receptor level in patients with bipolar disorder. BD, FC, mPFC
21  2015 Active immunization with Tocilizumab mimotopes induces specific immune responses. ADCC, ERK, FLS-RA, mIL-6R
22  2015 Association of inflammatory biomarkers with depressive symptoms and cognitive decline in a community-dwelling healthy older sample: a 3-year follow-up study. BDI, BMI, CDT, FAB, hs-CRP, IL, MMSE, sIL-2R, sIL-2R, TNF
23  2015 Circulating levels of interleukin 6 soluble receptor and its natural antagonist, sgp130, and the risk of myocardial infarction. AP, MI, sgp130, SHEEP
24  2015 Comparison of pro-inflammatory cytokines among patients with bipolar disorder and unipolar depression and normal controls. BD, BMI, CRP, MADRS, MCP-1, NC, SD, sIL-2R, sP-selectin, sTNF-R1, UD, YMRS
25  2015 Family-based association study of interleukin 6 (IL6) and its receptor (IL6R) functional polymorphisms in schizophrenia in the Polish population. IL-6
26  2015 Financial strain, inflammatory factors, and haemoglobin A1c levels in African American women. CRP, FACHS, HbA1c
27  2015 Higher proliferation of peritumoral endothelial cells to IL-6/sIL-6R than tumoral endothelial cells in hepatocellular carcinoma. HCC, IL-6, MVD, PECs, TECs
28  2015 Shedding of Endogenous Interleukin-6 Receptor (IL-6R) Is Governed by A Disintegrin and Metalloproteinase (ADAM) Proteases while a Full-length IL-6R Isoform Localizes to Circulating Microvesicles. ADAM, IL-6, IL-6R
29  2014 Comparison of inflammatory cytokine levels among type I/type II and manic/hypomanic/euthymic/depressive states of bipolar disorder. CRP, MCP-1, sIL-2R, sP-selectin, sTNF-R1
30  2014 Glycoprotein 130 polymorphism predicts soluble glycoprotein 130 levels. gp130, IL-6, sgp130
31  2014 Persistent inflammation and its relationship to leptin and insulin in phases of bipolar disorder from acute depression to full remission. hs-CRP, IL-1ra, sIL-2R, sTNF-R1
32  2014 Pro-inflammatory cytokine associated with somatic and pain symptoms in depression. BMI, CRP, MCP-1, sP-selectin, sTNF-R
33  2013 A new regulatory variant in the interleukin-6 receptor gene associates with asthma risk. ---
34  2013 IL-6 and its receptors in coronary artery disease and acute myocardial infarction. AMI, CAD, hs-CRP, IL-6, sGp130
35  2013 Pharmacokinetics and pharmacodynamics of tocilizumab after subcutaneous administration in patients with rheumatoid arthritis. CRP
36  2013 Soluble interleukin-6 receptor is a prognostic marker for relapse-free survival in estrogen receptor-positive breast cancer. IL-6, sgp130
37  2013 Soluble interleukin-6 receptor is a serum biomarker for the response of esophageal carcinoma to neoadjuvant chemoradiotherapy. ---
38  2013 The relationship between soluble receptor of interleukin-6 with angiogenic cytokines and proliferation markers in multiple myeloma. B2M, HGF, IL-18, Ki-67 PI, MM
39  2012 CD8+CD28-lymphocytes in peripheral blood and serum concentrations of soluble interleukin 6 receptor are increased in patients with Graves' orbitopathy and correlate with disease activity. GD, IL-6
40  2012 Influence of local inflammation of the peritoneal membrane on diuresis and residual renal function in patients treated with peritoneal dialysis. CAPD, IL-6, RRF
41  2012 Plasma concentrations of soluble cytokine receptors in euthymic bipolar patients with and without subsyndromal symptoms. sIL-2R, sTNF-R1, WC
42  2012 Soluble interleukin-6 receptor induces motor stereotypies and co-localizes with gp130 in regions linked to cortico-striato-thalamo-cortical circuits. BBB, CSTC
43  2011 Intrapituitary cytokines in Cushing's disease: do they play a role? CD, IL-1beta, IL-6
44  2010 A gain of function polymorphism in the interleukin 6 receptor influences RA susceptibility. ORs, RA
45  2010 Genotype at the sIL-6R A358C polymorphism does not influence response to anti-TNF therapy in patients with rheumatoid arthritis. ---
46  2010 Plasma soluble gp130 levels are increased in older subjects with metabolic syndrome. The role of insulin resistance. MS, sgp130
47  2010 The effect of exercise on plasma soluble IL-6 receptor concentration: a dichotomous response. DOMS, EIMD, sgp130
48  2009 Daily family assistance and inflammation among adolescents from Latin American and European backgrounds. CRP, IL-6
49  2008 Serum interleukin-6 receptor in polymyalgia rheumatica: a potential marker of relapse/recurrence risk. PMR, sgp130
50  2008 Serum interleukin-6, soluble interleukin-6 receptor and Crohn's disease activity. CD, CRP, IL-6, SEM
51  2007 Concentration of soluble interleukin-6 receptors in tears of allergic conjunctival disease patients. ACD, GAPDH, gp130
52  2007 Soluble IL-6 receptor in vitreous fluid of patients with proliferative diabetic retinopathy. ELISA, PDR, PPDR, VEGF
53  2006 Human T-cell leukemia virus type-I Tax induces expression of interleukin-6 receptor (IL-6R): Shedding of soluble IL-6R and activation of STAT3 signaling. HTLV-I, IL-6R
54  2006 Leptin, soluble interleukin-6 receptor, C-reactive protein and soluble vascular cell adhesion molecule-1 levels in human coronary atherosclerotic plaque. hs-CRP, sVCAM-1
55  2006 The regulatory role of Hyper-IL-6 in the differentiation of myeloid and erythroid progenitors derived from human cord blood. high, IL-6
56  2005 Chai-hu-gui-zhi-gan-jiang-tang regulates plasma interleukin-6 and soluble interleukin-6 receptor concentrations and improves depressed mood in climacteric women with insomnia. IL-6
57  2005 Inflammatory cytokines in pediatric cardiac surgery and variable effect of the hemofiltration process. CPB, IL-1, IL-6, IL-8, TNF-alpha
58  2005 Variability of serum levels of tumor necrosis factor-alpha, interleukin 6, and soluble interleukin 6 receptor over 2 years in young women. ICC, IL-6, TNF-alpha
59  2004 Acute changes in dietary omega-3 fatty acid intake lowers soluble interleukin-6 receptor in healthy adult normal weight and overweight males. ISO
60  2004 Effects of Viscum album extract therapy in patients with cancer: relation with interleukin-6, soluble interleukin-6 receptor, and soluble gp130. ELISA, IL, sgp130, VA
61  2004 Soluble interleukin-6 receptor (sIL-6R) in cerebrospinal fluid of patients with inflammatory and non inflammatory neurological diseases. BBB, CNS, CSF, gp130, HC, IL-6R, IND, MS, NIND, PPMS, RRMS
62  2003 Cytokine soluble receptors in perinatal and early neonatal life. MS, sIL-2R, sIL-4R, UC
63  2003 Cytokines in patients with ischaemic heart disease or myocardial infarction. AMI, IL-10, IL-6
64  2003 Effect of cyclooxygenase-2 inhibition with rofecoxib on endothelial dysfunction and inflammatory markers in patients with coronary artery disease. CAD, COX-2, CRP, FMD, NMD, sICAM-1
65  2003 Gammadelta T cells and interleukin-6 levels could provide information regarding the progression of human renal allograft. IL-6
66  2003 Neuroprotective effects of interleukin-6 on NMDA-induced rat retinal damage. IL-6, NMDA
67  2003 Pyrethroids used indoors--immune status of humans exposed to pyrethroids following a pest control operation--a one year follow-up study. PCO, sIL-2R
68  2002 Circulating IL-6 and sIL-6R in patients with hepatocellular carcinoma. ---
69  2002 Effect of soluble interleukin-6 receptor alpha and interleukin-6 secreted by polymorphonuclear leukocytes on tumor necrosis factor-alpha expression and its production by peripheral blood mononuclear cells. ELISA, IL, PBMC, PMN, TNF-alpha
70  2002 Multiplexed protein profiling on microarrays by rolling-circle amplification. DCs, IL, IP, LPS, MDC, MIP, RCA, sTNF-RI, TARC, TNF-alpha
71  2002 Oral contraceptives moderately effect bone resorption markers and serum-soluble interleukin-6 receptor concentrations. ---
72  2002 Production of growth related oncogene protein-alpha in human umbilical vein endothelial cells stimulated with soluble interleukin-6 receptor-alpha: role of signal transducers, janus kinase 2 and mitogen-activated kinase kinase. GRO-alpha, HUVEC, JAK2, MEK, SHP-2, STAT3
73  2002 Serum soluble IL-6 receptor levels during the mobilization of stem cells to peripheral blood. CFU-GM, PB
74  2002 Soluble interleukin 6 receptor (sIL-6R) mediates colonic tumor cell adherence to the vascular endothelium: a mechanism for metastatic initiation? CRP
75  2001 Serum levels of cytokines in children and adolescents with Graves' disease and non-toxic nodular goiter. GD, IL-6, IL-8, NTNG, RRA, TRAb
76  2001 The soluble interleukin 6 receptor: mechanisms of production and implications in disease. IL-6
77  2001 [Determination of serum soluble interleukin-6 receptor and soluble gp130 levels in patient with pregnancy induced hypertension and its significance]. ELISA, sgp130
78  2000 Analysis of soluble interleukin 6 receptor in cerebrospinal fluid in inflammatory and non-inflammatory conditions. CSF
79  2000 Correlation of estradiol, parathyroid hormone, interleukin-6, and soluble interleukin-6 receptor during the normal menstrual cycle. DPD, FP, IL-6, LP, PTH
80  2000 Serum levels of soluble interleukin 6 receptor and soluble gp130 are elevated in patients with localized scleroderma. sgp130, SSc
81  2000 Soluble IL-6 receptor levels in the seminal plasma of infertile patients with accessory gland infection. ---
82  2000 Soluble interleukin-6 receptor (sIL-6R) makes IL-6R negative T cell line respond to IL-6; it inhibits TNF production. IFN-gamma, IL-6, TNF
83  2000 The predictive value of biochemical markers of bone turnover for bone mineral density in postmenopausal Japanese women. BALP, BMD, HP, LP, OC, OC-N, YSM
84  2000 Urinary soluble IL-6 receptor levels after cardiopulmonary bypass. CPB, ECC
85  2000 [Examination and evaluation of sIL-6R, sgp130 in serum in patients with chronic hepatopathy]. CH, ELISA, NC
86  1999 C-reactive protein: a physiological activator of interleukin 6 receptor shedding. CRP
87  1999 Prognostic evaluation in multiple myeloma: an analysis of the impact of new prognostic factors. beta2m, HGF, ICTP, IL-6
88  1999 Soluble interleukin-6 (IL-6) receptor with IL-6 stimulates megakaryopoiesis from human CD34(+) cells through glycoprotein (gp)130 signaling. GP, IL-6, MKs, SCF, TPO
89  1999 [Cloning and secretory expression of soluble interleukin-6 receptor gene in Streptomyces lividans]. ---
90  1998 Cytokines and soluble CD4 and CD8 molecules in rheumatoid arthritis: relationship to systematic vasculitis and microvascular capillaroscopic abnormalities. IL-6, RA, sCD4, TNF-alpha
91  1998 Enhancement of beta-amyloid precursor protein transcription and expression by the soluble interleukin-6 receptor/interleukin-6 complex. betaAPP, IL-6
92  1998 Hepatocellular hyperplasia, plasmacytoma formation, and extramedullary hematopoiesis in interleukin (IL)-6/soluble IL-6 receptor double-transgenic mice. IL, IL-6
93  1998 High-level production of alternatively spliced soluble interleukin-6 receptor in serum of patients with adult T-cell leukaemia/HTLV-I-associated myelopathy. AFP, ANA, AS-sIL-6R, ATL, ELISA, HAM, HBV, HCV, HIV-1, HTLV-I, mAb, Sf9
94  1998 Plasmablastic morphology--an independent prognostic factor with clinical and laboratory correlates: Eastern Cooperative Oncology Group (ECOG) myeloma trial E9486 report by the ECOG Myeloma Laboratory Group. BCNU, ECOG, MM, PB, PC, rIFNalpha2
95  1998 Release of the soluble interleukin-6 receptor from human T-cells. IL-6, MB
96  1998 Serum soluble interleukin-6 receptor and biochemical markers of bone metabolism show significant variations during the menstrual cycle. ALP, Dpyr
97  1998 [Level of interleukin-6 (IL-6), soluble interleukin-6 receptors (sIL-6R) and tumor necrosis factor alpha (TNF-alpha) in untreated and progressing multiple myeloma]. IL-6, m-ST, PE, TNF-alpha
98  1997 Circulating levels of soluble interleukin-6 receptor in patients with bronchial asthma. ---
99  1997 Interleukin-6 and interleukin-6 receptor secretion by chronic lymphatic leukaemia and normal B lymphocytes: effect of PMA and PWM. CLL, IL-6, PMA, PWM
100  1997 Inverse correlation of interleukin-6 with soluble interleukin-6 receptor after transplantation of bone marrow or peripheral blood stem cells. IL-6