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Abbreviation : siRNA
Long Form : small inhibitory RNA
No. Year Title Co-occurring Abbreviation
2018 CD5 expression promotes IL-10 production through activation of the MAPK/Erk pathway and upregulation of TRPC1 channels in B lymphocytes. BCR, CLL, TRPC1
2018 High Throughput SiRNA Screening for Chloropicrin and Hydrogen Fluoride-Induced Cornea Epithelial Cell Injury. HTS
2018 RNA-targeted therapeutics for lipid disorders. ANGPTL3, apoC-III, ASO, LPA
2017 Silencing strategies for therapy of SOD1-mediated ALS. ALS, ASO, CNS, miR, RNAi, shRNA, SOD1
2016 Cyclin A1 expression and paclitaxel resistance in human ovarian cancer cells. CCNA1
2016 Decreased Expression of KIFC1 in Human Testes with Globozoospermic Defects. RT-PCR
2015 Chaperonin containing T-complex polypeptide subunit eta is a potential marker of joint contracture: an experimental study in the rat. alpha-SMA, CCT-eta, qRT-PCR, ROM
2015 Keratins and skin disease. ---
2015 Selective inhibition of histone deacetylase 2 induces p53-dependent survivin downregulation through MDM2 proteasomal degradation. HDAC2, SAHA
10  2015 Significance of SALL4 as a drug‑resistant factor in lung cancer. ES, PTX
11  2014 Constitutive and follicle-stimulating hormone-induced action of somatostatin receptor-2 on regulation of apoptosis and steroidogenesis in bovine granulosa cells. Bax, Bcl-2, FSH, GCs, SST, SSTR2
12  2014 Induction of hepatic apolipoprotein A-I gene expression by the isoflavones quercetin and isoquercetrin. apoA-I, HDL
13  2014 Induction of inducible nitric oxide synthase (iNOS) expression by oxLDL inhibits macrophage derived foam cell migration. iNOS, NO, oxLDL, ROS
14  2014 p38delta mitogen-activated protein kinase regulates the expression of tight junction protein ZO-1 in differentiating human epidermal keratinocytes. IIF, TJs, ZO-1
15  2014 V843I, a lung cancer predisposing EGFR mutation, is responsible for resistance to EGFR tyrosine kinase inhibitors. EGFR, TKIs
16  2013 Casticin induces ovarian cancer cell apoptosis by repressing FoxM1 through the activation of FOXO3a. ELISA, FoxM1, Plk1, RT-PCR
17  2013 Proteomic identification of mitochondrial targets of arginase in human breast cancer. Arg II, mSHMT, NOHA
18  2013 Roles for cytosolic NADPH redox in regulating pulmonary artery relaxation by thiol oxidation-elicited subunit dimerization of protein kinase G1alpha. 6-AN, BPA, G6PD, sGC, Trx-1, TrxR-1, VASP
19  2012 Docosahexaenoic acid mediates peroxisomal elongation, a prerequisite for peroxisome division. ---
20  2012 Electrophoretic mobility shift assay analysis of NFkappaB transcriptional regulation by nuclear IkappaBalpha. EMSA
21  2012 Flotillin-2 is an acrosome-related protein involved in mouse spermiogenesis. ---
22  2012 Hailey-Hailey disease and tight junctions: Claudins 1 and 4 are regulated by ATP2C1 gene encoding Ca(2+) /Mn(2+) ATPase SPCA1 in cultured keratinocytes. TJ
23  2012 Lack of expression and function of erythropoietin receptors in the kidney. EPOR, ESAs
24  2012 Nerve growth factor modulates human rhinovirus infection in airway epithelial cells by controlling ICAM-1 expression. HRV, ICAM-1, NGF, TrkA
25  2011 Acidic fibroblast growth factor (FGF) potentiates glial-mediated neurotoxicity by activating FGFR2 IIIb protein. aFGF, FGF
26  2011 Biologically inhibitory effects of VEGF siRNA on endometrial carcinoma cells. CPE, FQ-PCR, VEGF
27  2011 Calpastatin is regulated by protein never in mitosis gene A interacting-1 (PIN1) in endothelial cells. GST, MAEC, PIN1, sh
28  2011 Decreasing lactate level and increasing antibody production in Chinese Hamster Ovary cells (CHO) by reducing the expression of lactate dehydrogenase and pyruvate dehydrogenase kinases. CHO, LDH, LDHA, PDHKs, PDHs
29  2011 Targeted knockdown of canine KIT (stem cell factor receptor) using RNA interference. B2M, CHO, GAPDH
30  2010 Anti-inflammatory effect of MUC1 during respiratory syncytial virus infection of lung epithelial cells in vitro. RSV, TNFR
31  2010 Chaperonin containing T-complex polypeptide subunit eta (CCT-eta) is a specific regulator of fibroblast motility and contractility. alpha-SMA, CCT-eta, CCT-eta, EGF, PDGF
32  2010 Depletion of GSH in glial cells induces neurotoxicity: relevance to aging and degenerative neurological diseases. BSO, CTM
33  2010 Evaluation of efficacy, biodistribution, and inflammation for a potent siRNA nanoparticle: effect of dexamethasone co-treatment. DEX, GR, MAPK
34  2010 Fas-associated factor 1 is a negative regulator in capsaicin induced cancer cell apoptosis. CP, FAF1, I-RTX
35  2010 Nonviral transfection of mouse calvarial organ in vitro using Accell-modified siRNA. ---
36  2010 Roles for Nox4 in the contractile response of bovine pulmonary arteries to hypoxia. BPA, HPV, TGF
37  2009 Functional involvement of protein kinase C-betaII and its substrate, myristoylated alanine-rich C-kinase substrate (MARCKS), in insulin-stimulated glucose transport in L6 rat skeletal muscle cells. ISGT, MARCKS, PI3K, PKC, PLD1
38  2009 Harnessing RNA interference to develop neonatal therapies: from Nobel Prize winning discovery to proof of concept clinical trials. RNAi
39  2009 Interleukin-8 is essential for normal urothelial cell survival. IL-8
40  2009 siRNA and DNA transfer to cultured cells. ---
41  2009 The role of survivin in the resistance of endometriotic stromal cells to drug-induced apoptosis. ESCs, IAP, SS
42  2009 Wilms' tumour gene 1 (WT1) as a target in curcumin treatment of pancreatic cancer cells. WT1
43  2008 Lactate stimulates vasculogenic stem cells via the thioredoxin system and engages an autocrine activation loop involving hypoxia-inducible factor 1. HIF-1, SDF-1, SPCs, Trx1, TrxR, VEGF
44  2008 Suppression of sphingomyelin synthase 1 by small interference RNA is associated with enhanced ceramide production and apoptosis after photodamage. ---
45  2008 The ERBB3 receptor in cancer and cancer gene therapy. EGFR
46  2007 Activation of FAK is necessary for the osteogenic differentiation of human mesenchymal stem cells on laminin-5. ECM, ERK, FAK, hMSC
47  2007 Base excision repair proteins are required for integrin-mediated suppression of bleomycin-induced DNA breakage in murine lung endothelial cells. BER, BLM, MLECs, PARP, XRCC1
48  2007 Curcumin [1,7-bis(4-hydroxy-3-methoxyphenyl)-1-6-heptadine-3,5-dione; C21H20O6] sensitizes human prostate cancer cells to tumor necrosis factor-related apoptosis-inducing ligand/Apo2L-induced apoptosis by suppressing nuclear factor-kappaB via inhibition of the prosurvival Akt signaling pathway. NF, p-Akt, XIAP
49  2007 Knockdown of survivin expression by siRNA induces apoptosis of hepatocellular carcinoma cells. AI, GIR, PI
50  2007 Radiation-induced cellular DNA damage repair response enhances viral gene therapy efficacy in the treatment of malignant pleural mesothelioma. MPM, RT
51  2007 RelA is required for IL-1beta stimulation of Matrix Metalloproteinase-1 expression in chondrocytes. HAC, IL-1beta, MMP-1, NF-kappaB
52  2007 Selective gene silencing of either MMP-2 or MMP-9 inhibits invasion of human saphenous vein smooth muscle cells. MMPs, SMC, SV
53  2007 Selective regulation of somatostatin receptor subtype signaling: evidence for constitutive receptor activation. ssts
54  2007 The therapeutic potential of siRNA in gene therapy of neurodegenerative disorders. AD, ALS, HD
55  2006 c-Myb is an essential downstream target for homeobox-mediated transformation of hematopoietic cells. E2A-HLF, MLL-ENL, RT-PCR
56  2006 Effects of Raf-1 siRNA on human cerebral microvascular endothelial cells: a potential therapeutic strategy for inhibition of tumor angiogenesis. HCMEC
57  2006 ERK1/2 and p38 MAP kinase control MMP-2, MT1-MMP, and TIMP action and affect cell migration: a comparison between mesothelioma and mesothelial cells. ECM, MMP, MT1-MMP, PCR, PDGF, TGF, TIMP
58  2006 Glutathione peroxidase 2, the major cigarette smoke-inducible isoform of GPX in lungs, is regulated by Nrf2. GPx, Nrf2
59  2006 Obscurin modulates the assembly and organization of sarcomeres and the sarcoplasmic reticulum. SR
60  2006 Targeting the NF-kappa B pathway in estrogen receptor negative MDA-MB-231 breast cancer cells using small inhibitory RNAs. ---
61  2005 A novel thiol oxidation-based mechanism for adriamycin-induced cell injury in human macrophages. DCFH, GR, Grx
62  2005 Cationic lipid saturation influences intracellular delivery of encapsulated nucleic acids. DLenDMA, DLinDMA, DODMA, SNALPs
63  2005 Delivery of small interfering RNA to mammalian cells in culture by using cationic lipid/polymer-based transfection reagents. RNAi
64  2005 FOXO1 functions as a master switch that regulates gene expression necessary for tumor necrosis factor-induced fibroblast apoptosis. FoxO1, TNF-alpha
65  2005 Heat shock protein 90 inhibition sensitizes acute myelogenous leukemia cells to cytarabine. 17-AAG, 17-AG, AML, ATR, Chk1, Hsp90, PI3K
66  2005 Introduction of a survivin gene-specific small inhibitory RNA inhibits growth of pancreatic cancer cells. ---
67  2005 New perspectives on neoplasia and the RNA world. miRNA, ncRNA
68  2005 Nox4 is critical for hypoxia-inducible factor 2-alpha transcriptional activity in von Hippel-Lindau-deficient renal cell carcinoma. HIF-alpha, RCC, VHL, WT
69  2005 Optimized transfection of diced siRNA into mature primary human osteoclasts: inhibition of cathepsin K mediated bone resorption by siRNA. RISC
70  2005 Potentiation of glucocorticoid activity in hypoxia through induction of the glucocorticoid receptor. GR
71  2005 Rab proteins regulate epithelial sodium channel activity in colonic epithelial HT-29 cells. ---
72  2005 Suppression of RAD21 gene expression decreases cell growth and enhances cytotoxicity of etoposide and bleomycin in human breast cancer cells. DRF50, DSB
73  2005 The role of LIP5 and CHMP5 in multivesicular body formation and HIV-1 budding in mammalian cells. EGFR, HIV-1, MVB
74  2004 Functional analysis of focal adhesion kinase (FAK) reduction by small inhibitory RNAs. EGF, FAK
75  2004 Noninvasive delivery of small inhibitory RNA and other reagents to pulmonary alveoli in mice. ATRA, CRBP, GAPDH
76  2004 RNA molecules as anti-cancer agents. DKS, dsRNA
77  2003 IL-1alpha-induced COX-2 expression in human intestinal myofibroblasts is dependent on a PKCzeta-ROS pathway. BIS, CC, COX-2, DCF, IL, IMFs, IPK, MAPK, NF-kappaB, PKC, ROS
78  2003 Inhibition of pancreatic cancer cell growth and induction of apoptosis with novel therapies directed against protein kinase A. PKA
79  2003 Silencing of H-ras gene expression by retrovirus-mediated siRNA decreases transformation efficiency and tumorgrowth in a model of human ovarian cancer. GFP
80  2003 siRNA depletion of BRCA1, but not BRCA2, causes increased genome instability in Fanconi anemia cells. FA, ICLs
81  2003 The p38 mitogen-activated protein kinase pathway links the DNA mismatch repair system to the G2 checkpoint and to resistance to chemotherapeutic DNA-methylating agents. MMR, TMZ