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Abbreviation : uPA
Long Form : urokinase-type PA
No. Year Title Co-occurring Abbreviation
2018 Effects of 17beta-estradiol, Interleukin-1beta, and Human Chorionic Gonadotropin on Activity and mRNA Expression of Plasminogen Activators in Porcine Endometrial Cells. hCG, IL-1beta, PAs
2018 Effects of gestational hypertension and pre-eclampsia in mRNA expression of fibrinolysis genes in primary cultured human umbilical vein endothelial cells. HD, HUVEC, PAI-1, PRE
2018 Effects of Progesterone and 17beta-Estradiol under Presence or Absence of FBS on Plasminogen Activators Activity in Porcine Uterine Epithelial Cells. FBS, PAs, pUECs, tPA, uPAR
2017 Kallistatin Suppresses Cell Proliferation and Invasion and Promotes Apoptosis in Cervical Cancer Through Blocking NF-kappaB Signaling. EMT, VEGF
2017 PAI-1 is a critical regulator of FGF23 homeostasis. FGF23, PAI-1, PAs, tPA
2015 Proteolytic regulation of epithelial sodium channels by urokinase plasminogen activator: cutting edge and cleavage sites. ENaC, PAI-1, tPA
2014 Vascular aneurysms: a perspective. MMPs, PAI-1, tPA
2013 LRP-1: a checkpoint for the extracellular matrix proteolysis. ECM, MMP
2013 Regulation of plasminogen activator activity and expression by cyclic mechanical stress in rat mandibular condylar chondrocytes. MCCs, PA, TMJ, tPA, uPAR
10  2013 Tissue-type plasminogen activator and plasminogen embedded in casein rule its degradation under physiological situations: manipulation with casein hydrolysate. Pg, tPA
11  2012 Mice deficient in urokinase-type plasminogen activator have delayed healing of tympanic membrane perforations. PAs, TM, tPA
12  2012 Tumor necrosis factor alpha stimulates expression and secretion of urokinase plasminogen activator in human dental pulp cells. PA, TNF-alpha, tPA
13  2011 Beneficial and detrimental effects of plasmin(ogen) during infection and sepsis in mice. tPA, WT
14  2011 Development of inhibitors of plasminogen activator inhibitor-1. HTS, PAI-1
15  2010 Characterization of a novel class of polyphenolic inhibitors of plasminogen activator inhibitor-1. PAI-1
16  2010 Effects of intra-articular administration of sodium hyaluronate on plasminogen activator system in temporomandibular joints with osteoarthritis. OA, PA, PAI-1, SH, suPAR, TMJ
17  2010 Hyperfibrinolysis, uPA/suPAR system, kynurenines, and the prevalence of cardiovascular disease in patients with chronic renal failure on conservative treatment. CRF, CVD, KYN, PAP, QA, suPAR, Trp
18  2010 Regulation of airway contractility by plasminogen activators through N-methyl-D-aspartate receptor-1. ACh, PAs, tPA
19  2009 Role of hypoxia-inducible factor-1 alpha in the regulation of plasminogen activator activity in rat knee joint chondrocytes. ChIP, ELISA, HIF-1alpha, HRE, IL-1beta, PA, PAI-1, RT-PCR, t-PA, uPAR
20  2009 Two distinct expression patterns of urokinase, urokinase receptor and plasminogen activator inhibitor-1 in colon cancer liver metastases. PAI-1
21  2008 Components of the plasminogen activator system and their complexes in renal cell and bladder cancer: comparison between normal and matched cancerous tissues. PA, PAI, RCC, tPA
22  2008 Effects of different molecular weight hyaluronan products on the expression of urokinase plasminogen activator and inhibitor and gelatinases during the early stage of osteoarthritis. HA, MMP, MW, OA, PA, PAI-1
23  2008 Naproxen, meloxicam and methylprednisolone inhibit urokinase plasminogen activator and inhibitor and gelatinases expression during the early stage of osteoarthritis. ELISA, MMP, OA, PA, PAI-1
24  2008 Protein kinase C synergistically stimulates tumor necrosis factor-alpha-induced secretion of urokinase-type plasminogen activator in human dental pulp cells. PA, PKC, PMA, TNF-alpha, tPA
25  2007 Changes to plasminogen activators and matrix metalloproteinase-9 in dogs with toxocarosis. MMP-9, PAs, tPA
26  2007 IL-1beta stimulates urokinase-type plasminogen activator expression and secretion in human dental pulp cells. IL-1beta, PA, tPA
27  2007 Involvement of plasminogen activator and plasminogen activator inhibitor type 1 in spermatogenesis, sperm capacitation, and fertilization. PA, PAI-1, tPA, uPAR
28  2006 Activity and nature of plasminogen activators associated with the casein micelle. PA, PL, tPA
29  2006 Glucosamine sulfate suppresses the expressions of urokinase plasminogen activator and inhibitor and gelatinases during the early stage of osteoarthritis. MMP-2 and -9, OA, PA, PAI-1
30  2006 Nicotine treatment induces expression of matrix metalloproteinases in human osteoblastic Saos-2 cells. M-CSF, MMPs, PAI-1, PCR, PGE2, TIMPs, tPA
31  2006 Plasminogen activation independent of uPA and tPA maintains wound healing in gene-deficient mice. MMP, pKal, PLG
32  2006 The effect of tissue type-plasminogen activator deletion and associated fibrin(ogen) deposition on macrophage localization in peritoneal inflammation. PAs, t-PA
33  2006 Urokinase-type plasminogen activator supports liver repair independent of its cellular receptor. PLG, uPAR
34  2006 Urokinase-type plasminogen activator, receptor, and inhibitor correlating with gelatinase-B (MMP-9) contribute to inflammation in gouty arthritis of the knee. MMP-2, OA, PA, PAI-1, SF, suPAR
35  2005 Expression of plasminogen activators in preimplantation rat embryos developed in vivo and in vitro. PAs
36  2005 Inhibition of human trophoblast invasiveness by high glucose concentrations. PA
37  2005 mRNA analysis of several components of the plasminogen activator and matrix metalloproteinase systems in endometriosis using a real-time quantitative RT-PCR assay. MMP, PA, PAI-1
38  2005 Plasminogen activator system in smokers and non-smokers with and without periodontal disease. GCF, PA, PAI-1, PAI-2, t-PA
39  2005 The gp130 ligand oncostatin M regulates tissue inhibitor of metalloproteinases-1 through ERK1/2 and p38 in human adult cardiac myocytes and in human adult cardiac fibroblasts: a possible role for the gp130/gp130 ligand system in the modulation of extracellular matrix degradation in the human heart. CT-1, IL-6, LIF, MMPs, OSM, TIMPs
40  2005 The plasminogen activator/plasmin system is essential for development of the joint inflammatory phase of collagen type II-induced arthritis. CII, PA
41  2004 Compartment- and cell-specific expression of coagulation and fibrinolysis factors in the murine lung undergoing inhalational versus intravenous endotoxin application. AM, EC, LPS, PAI-1, PBC, SMC, TF, TFPI, tPA
42  2004 Differences in the implantation rates of rat embryos developed in vivo and in vitro: possible role for plasminogen activators. ---
43  2004 Expression of active plasminogen activator inhibitor-1 reduces cell migration and invasion in breast and gynecological cancer cells. PAI-1
44  2004 Plasminogen activator/plasminogen activator inhibitors in ovarian physiology. CL, ECM, PA, PAI, tPA
45  2004 [How chronic prostatitis affects plasminogen activator system]. PA, tPA
46  2003 A Kunitz-type protease inhibitor, bikunin, inhibits ovarian cancer cell invasion by blocking the calcium-dependent transforming growth factor-beta 1 signaling cascade. PA, PAI-1, TGF-beta1
47  2003 Endogenous alpha2-antiplasmin does not enhance glomerular fibrin deposition or injury in glomerulonephritis. alpha2-AP, GN, tPA
48  2003 Enhancement of fibrinolytic activity of bovine aortic endothelial cells by ginsenoside Rb2. BAEC, PA, PAI-1, uPAR
49  2003 Expression of several components of the plasminogen activator and matrix metalloproteinase systems in endometriosis. MMP, PA, PAI-1, TIMP-1
50  2003 Expression of type-1 plasminogen activator inhibitor in the kidney of diabetic rat models. LETO, OLETF, STZ, tPA
51  2003 Expression pattern and functional studies of matrix degrading proteases and their inhibitors in the mouse corpus luteum. CL, MMPs, MT1-MMP, PAs, TIMP-3
52  2003 Inhibition of cell surface mediated plasminogen activation by a monoclonal antibody against alpha-Enolase. mAb
53  2003 Overexpression of Hsp27 in a human melanoma cell line: regulation of E-cadherin, MUC18/MCAM, and plasminogen activator (PA) system. FACS, IF, PA
54  2003 Proteases in brain tumour progression. Cats, MMPs, PAs, tPA
55  2002 Biphasic regulation of plasminogen activator/inhibitor by LDL in mesangial cells. HMC, LDL, PA, PAI-1, PKC, tPA
56  2002 Interaction of plasminogen activator inhibitor type-1 (PAI-1) with vitronectin (Vn): mapping the binding sites on PAI-1 and Vn. PAI-1, SMB, VN
57  2002 Interaction of plasminogen activator inhibitor type-1 (PAI-1) with vitronectin. Hep, PAI-1, VN
58  2002 Pituitary adenylate cyclase-activating polypeptide modulates plasminogen activator expression in rat granulosa cell. PACAP, PAs, tPA, VIP
59  2002 Plasminogen activator inhibitor 1 expression is regulated by the inflammatory mediators interleukin-1alpha, tumor necrosis factor-alpha, transforming growth factor-beta and oncostatin M in human cardiac myocytes. HACM, IL-1 alpha, OSM, PA, PAI-1, t-PA, TGF-beta, TNF-alpha
60  2002 Thyroid follicular cells secrete plasminogen activators and can form angiostatin from plasminogen. ---
61  2001 Control of mouse cumulus cell-oocyte complex integrity before and after ovulation: plasminogen activator synthesis and matrix degradation. CCs, COC, PA
62  2001 Elements of the fibrinolytic system. MMP, PA, PAI, t-PA, u-PAR
63  2001 Functional evaluation of plasmin formation in primary breast cancer. PA, tPA
64  2001 Plasmin-dependent and -independent effects of plasminogen activators and inhibitor-1 on ex vivo angiogenesis. PA, PLG, tPA
65  2001 Plasmin-mediated fibroblast growth factor-2 mobilisation supports smooth muscle cell proliferation in human saphenous vein. FGF-2, NALME
66  2001 Polyphyenolics increase t-PA and u-PA gene transcription in cultured human endothelial cells. HUVECs, RT-PCR
67  2001 Prognostic significance of the combined expression of matrix metalloproteinase-9, urokinase type plasminogen activator and its receptor in breast cancer as measured by Northern blot analysis. ---
68  2001 Reciprocal regulation of tissue-type and urokinase-type plasminogen activators in the differentiation of murine preadipocyte line 3T3-L1 and the hormonal regulation of fibrinolytic factors in the mature adipocytes. GLUT4, GPDH, IBMX, tPA
69  2001 Response of bovine endothelial cells to FGF-2 and VEGF is dependent on their site of origin: Relevance to the regulation of angiogenesis. BAE, BME, PA, TSP-1, VEGF
70  2001 Synergistic induction of t-PA by vascular endothelial growth factor and basic fibroblast growth factor and localization of t-PA to Weibel-Palade bodies in bovine microvascular endothelial cells. BAE cells, bFGF, BME cells, PA, tPA, tPA, VEGF
71  2001 The plasminogen activator inhibitor PAI-1 controls in vivo tumor vascularization by interaction with proteases, not vitronectin. Implications for antiangiogenic strategies. PA, PAI-1, PLG, tPA, VN
72  2001 [Source of plasminogen activator in rhesus monkey semen and its possible role in sperm capacitation]. AR, PA, PAI-1, t-PA, TE
73  2000 Fibrinolysis: an unfinished agenda. tPA
74  2000 High tPA-expression in primary melanoma of the limb correlates with good prognosis. PA
75  2000 Increased TIMP/MMP ratio in varicose veins: a possible explanation for extracellular matrix accumulation. PAI-1, PAs
76  2000 Modulation of urokinase-type and tissue-type plasminogen activator occurs at an early stage of progressing stages of chronic venous insufficiency. CVI, tPA
77  2000 Pocket protein-independent repression of urokinase-type plasminogen activator and plasminogen activator inhibitor 1 gene expression by E2F1. PA, PAI-1
78  1999 Antisense oligonucleotide of tissue inhibitor of metalloproteinase-1 induces the plasminogen activator activity in periodontal ligament cells. MMPs, PA, PDL, TIMPs
79  1999 Co-localization of urokinase and its receptor on established human umbilical vein endothelial cell. PAI-1, PAs, PMA, tPA, uPAR
80  1999 Depressed urokinase activity in bronchoalveolar lavage fluid from patients with sarcoidosis, silicosis or idiopathic pulmonary Rbrosis: relationship to disease severity. BALF, ILD, IPF, PAs, tPA
81  1999 Effect of retinoic acid on plasminogen activator expression in human melanoma cells. ELISA, RA, RAR
82  1999 ELISA for complexes of urokinase-type and tissue-type plasminogen activators with their type-1 inhibitor (uPA-PAI-1 and tPA-PAI-1). t-PA
83  1999 Hepatocyte growth factor increases expression of vascular endothelial growth factor and plasminogen activator inhibitor-1 in human keratinocytes and the vascular endothelial growth factor receptor flk-1 in human endothelial cells. HGF/SF, MSP, PA, PAI-1, tPA, VEGF
84  1999 Implications of decidualization-associated protease expression in implantation and menstruation. DZ, ECM, HESCs, MMPs, MPA, PAs, tPA
85  1999 Production of plasminogen activators (PAs) in bovine cumulus-oocyte complexes during maturation in vitro: effects of epidermal growth factor on production of PAs in oocytes and cumulus cells. COCs, EGF, PAs, tPA, tPA-PAI
86  1999 Regulation of the plasminogen activator system in the ovary. CL, ECM, PA, PAI, tPA
87  1998 Irsogladine maleate inhibits angiogenesis in wild-type and plasminogen activator-deficient mice. bFGF, IM, PA
88  1998 Mouse trophoblastic cell lines: II--Relationship between invasive potential and proteases. CE, CM
89  1998 Patterns of expression of fibrinolytic genes and matrix metalloproteinase-9 in dissecting aortic aneurysms. MMP-9, PAI-1, tPA
90  1998 Reduced transplant arteriosclerosis in plasminogen-deficient mice. MMPs, PA, tPA
91  1998 The crystal structure of the novel snake venom plasminogen activator TSV-PA: a prototype structure for snake venom serine proteinases. TSV-PA
92  1998 The effects of sex steroids on plasma levels of marker proteins of endothelial cell functioning. big ET-1, PAI-1, tPA, vWF
93  1998 The plasminogen activator system in pancreas cancer: role of t-PA in the invasive potential in vitro. PAs, tPA
94  1998 Upregulation of urokinase in alveolar macrophages and lung tissue in response to silica particles. BAL, PA
95  1997 Effect of transforming growth factor-beta on the plasminogen activator system in cultured first trimester human cytotrophoblasts. ELISA, PAI-1, PAs, TGF-beta
96  1997 Evidence for a role of the ovarian surface epithelium in the ovulatory mechanism of the sheep: secretion of urokinase-type plasminogen activator. LHRH
97  1997 Expression of urokinase-type plasminogen activator and its receptor during ovarian follicular development. PAI-1, tPA
98  1997 Stimulation of plasminogen activator/plasmin system in gingival fibroblast cells by oxygen radicals. Gin cells, HX, PA, XOD
99  1997 Studies of mice lacking plasminogen activator gene function suggest that plasmin production prior to ovulation exceeds the amount needed for optimal ovulation efficiency. PA, PAI-1, tPA
100  1997 Upregulation of urokinase-type plasminogen activator by endogenous and exogenous HIV-1 Tat protein in tumour cell lines derived from BK virus/tat-transgenic mice. BKV, CAT, LTR, PA, PAI